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Impact of aromatase inhibitor treatment on global gene expression and its association with antiproliferative response in ER+ breast cancer in postmenopausal patients.

Gao Q, López-Knowles E, Cheang MCU, Morden J, Ribas R, Sidhu K, Evans D, Martins V, Dodson A, Skene A, Holcombe C, Mallon E, Evans A, Bliss JM, Robertson J, Smith I, Martin LA, Dowsett M; POETIC Trial Management Group and Trialists.

Breast Cancer Res. 2019 Dec 31;22(1):2. doi: 10.1186/s13058-019-1223-z.


In silico Identification of a Molecular Circadian System With Novel Features in the Crustacean Model Organism Parhyale hawaiensis.

Hunt BJ, Mallon EB, Rosato E.

Front Physiol. 2019 Oct 18;10:1325. doi: 10.3389/fphys.2019.01325. eCollection 2019.


Methylation and gene expression differences between reproductive and sterile bumblebee workers.

Marshall H, Lonsdale ZN, Mallon EB.

Evol Lett. 2019 Aug 5;3(5):485-499. doi: 10.1002/evl3.129. eCollection 2019 Oct.


The effects of the neonicotinoid imidacloprid on gene expression and DNA methylation in the buff-tailed bumblebee Bombus terrestris.

Bebane PSA, Hunt BJ, Pegoraro M, Jones ARC, Marshall H, Rosato E, Mallon EB.

Proc Biol Sci. 2019 Jun 26;286(1905):20190718. doi: 10.1098/rspb.2019.0718. Epub 2019 Jun 19.


Deleterious Mutation Accumulation in Arabidopsis thaliana Pollen Genes: A Role for a Recent Relaxation of Selection.

Harrison MC, Mallon EB, Twell D, Hammond RL.

Genome Biol Evol. 2019 Jul 1;11(7):1939-1951. doi: 10.1093/gbe/evz127.


A paediatric puzzle: pulsating, pruritic papules and plaques.

Nicholson P, Wilmot MC, Chan I, Mallon E, Carton J, Hewitt C.

Clin Exp Dermatol. 2019 Aug;44(6):699-700. doi: 10.1111/ced.13830. Epub 2018 Nov 12. No abstract available.


Predictive Biomarkers for Endocrine Therapy: Retrospective Study in Tamoxifen and Exemestane Adjuvant Multinational (TEAM) Trial.

Roseweir AK, Bennett L, Dickson A, Cheng K, Quintayo MA, Bayani J, McMillan DC, Horgan PG, van de Velde CJH, Seynaeve C, Hasenburg A, Kieback DG, Markopoulos C, Dirix LY, Rea DW, Mallon EA, Bartlett JMS, Edwards J.

J Natl Cancer Inst. 2018 Jun 1;110(6):616-627. doi: 10.1093/jnci/djx255.


Major Impact of Sampling Methodology on Gene Expression in Estrogen Receptor-Positive Breast Cancer.

Gao Q, López-Knowles E, U Cheang MC, Morden J, Ribas R, Sidhu K, Evans D, Martins V, Dodson A, Skene A, Holcombe C, Mallon E, Evans A, Bliss JM, Robertson J, Smith I, Martin LA, Dowsett M; POETIC Trial Management Group and Trialists.

JNCI Cancer Spectr. 2018 May 22;2(2):pky005. doi: 10.1093/jncics/pky005. eCollection 2018 Apr.


Population-based study of the sensitivity of axillary ultrasound imaging in the preoperative staging of node-positive invasive lobular carcinoma of the breast.

Morrow E, Lannigan A, Doughty J, Litherland J, Mansell J, Stallard S, Mallon E, Romics L.

Br J Surg. 2018 Jul;105(8):987-995. doi: 10.1002/bjs.10791. Epub 2018 Apr 5.


Comparison of the Performance of 6 Prognostic Signatures for Estrogen Receptor-Positive Breast Cancer: A Secondary Analysis of a Randomized Clinical Trial.

Sestak I, Buus R, Cuzick J, Dubsky P, Kronenwett R, Denkert C, Ferree S, Sgroi D, Schnabel C, Baehner FL, Mallon E, Dowsett M.

JAMA Oncol. 2018 Apr 1;4(4):545-553. doi: 10.1001/jamaoncol.2017.5524.


Cave Pearl Data Logger: A Flexible Arduino-Based Logging Platform for Long-Term Monitoring in Harsh Environments.

Beddows PA, Mallon EK.

Sensors (Basel). 2018 Feb 9;18(2). pii: E530. doi: 10.3390/s18020530.


Alternative splicing associated with phenotypic plasticity in the bumble bee Bombus terrestris.

Price J, Harrison MC, Hammond RL, Adams S, Gutierrez-Marcos JF, Mallon EB.

Mol Ecol. 2018 Feb;27(4):1036-1043. doi: 10.1111/mec.14495. Epub 2018 Feb 11.


Allele specific expression and methylation in the bumblebee, Bombus terrestris.

Lonsdale Z, Lee K, Kiriakidu M, Amarasinghe H, Nathanael D, O'Connor CJ, Mallon EB.

PeerJ. 2017 Sep 13;5:e3798. doi: 10.7717/peerj.3798. eCollection 2017.


Do social insects support Haig's kin theory for the evolution of genomic imprinting?

Pegoraro M, Marshall H, Lonsdale ZN, Mallon EB.

Epigenetics. 2017 Sep;12(9):725-742. doi: 10.1080/15592294.2017.1348445. Review.


HER2 status predicts for upfront AI benefit: A TRANS-AIOG meta-analysis of 12,129 patients from ATAC, BIG 1-98 and TEAM with centrally determined HER2.

Bartlett JMS, Ahmed I, Regan MM, Sestak I, Mallon EA, Dell'Orto P, Thürlimann B, Seynaeve C, Putter H, Van de Velde CJH, Brookes CL, Forbes JF, Viale G, Cuzick J, Dowsett M, Rea DW; Translational Aromatase Inhibitor Overview Group (Trans-AIOG).

Eur J Cancer. 2017 Jul;79:129-138. doi: 10.1016/j.ejca.2017.03.033. Epub 2017 May 8.


The relationship between members of the canonical NF-κB pathway, components of tumour microenvironment and survival in patients with invasive ductal breast cancer.

Bennett L, Mallon EA, Horgan PG, Paul A, McMillan DC, Edwards J.

Oncotarget. 2017 May 16;8(20):33002-33013. doi: 10.18632/oncotarget.16031.


Phosphorylation of androgen receptors at serine 515 is a potential prognostic marker for triple negative breast cancer.

Roseweir AK, McCall P, Scott A, Liew B, Lim Z, Mallon EA, Edwards J.

Oncotarget. 2017 Jun 6;8(23):37172-37185. doi: 10.18632/oncotarget.16420.


Oncoplastic breast conservation surgery is oncologically safe when compared to wide local excision and mastectomy.

Mansell J, Weiler-Mithoff E, Stallard S, Doughty JC, Mallon E, Romics L.

Breast. 2017 Apr;32:179-185. doi: 10.1016/j.breast.2017.02.006. Epub 2017 Feb 17.


Oncological Outcomes and Complications After Volume Replacement Oncoplastic Breast Conservations-The Glasgow Experience.

Ho W, Stallard S, Doughty J, Mallon E, Romics L.

Breast Cancer (Auckl). 2016 Dec 19;10:223-228. doi: 10.4137/BCBCR.S41017. eCollection 2016.


High IKKα expression is associated with reduced time to recurrence and cancer specific survival in oestrogen receptor (ER)-positive breast cancer.

Bennett L, Quinn J, McCall P, Mallon EA, Horgan PG, McMillan DC, Paul A, Edwards J.

Int J Cancer. 2017 Apr 1;140(7):1633-1644. doi: 10.1002/ijc.30578. Epub 2017 Jan 6.


Acute and chronic gregarisation are associated with distinct DNA methylation fingerprints in desert locusts.

Mallon EB, Amarasinghe HE, Ott SR.

Sci Rep. 2016 Oct 18;6:35608. doi: 10.1038/srep35608.


The combined endocrine receptor in breast cancer, a novel approach to traditional hormone receptor interpretation and a better discriminator of outcome than ER and PR alone.

Campbell EJ, Tesson M, Doogan F, Mohammed ZMA, Mallon E, Edwards J.

Br J Cancer. 2016 Oct 11;115(8):967-973. doi: 10.1038/bjc.2016.206. Epub 2016 Sep 22.


Radiotherapy-associated Pemphigus - a Rare Cause of Grade 4 Skin Toxicity.

O'Leary B, Alarcon L, Mallon E, Kirby A.

Clin Oncol (R Coll Radiol). 2017 Jan;29(1):e50. doi: 10.1016/j.clon.2016.08.013. Epub 2016 Sep 8. No abstract available.


Six-year follow-up of patients treated with oncoplastic reduction mammoplasty: A cohort study.

Kabir SA, Stallard S, Weiler-Mithoff E, Mansell J, Mallon E, Doughty JC, Romics L Jr.

Int J Surg. 2016 Feb;26:38-42. doi: 10.1016/j.ijsu.2016.01.001. Epub 2016 Jan 4.


Large-scale structure of brown rat (Rattus norvegicus) populations in England: effects on rodenticide resistance.

Haniza MZ, Adams S, Jones EP, MacNicoll A, Mallon EB, Smith RH, Lambert MS.

PeerJ. 2015 Dec 7;3:e1458. doi: 10.7717/peerj.1458. eCollection 2015.


Outcomes of special histotypes of breast cancer after adjuvant endocrine therapy with letrozole or tamoxifen in the monotherapy cohort of the BIG 1-98 trial.

Munzone E, Giobbie-Hurder A, Gusterson BA, Mallon E, Viale G, Thürlimann B, Ejlertsen B, MacGrogan G, Bibeau F, Lelkaitis G, Price KN, Gelber RD, Coates AS, Goldhirsch A, Colleoni M; International Breast Cancer Study Group and the BIG 1-98 Collaborative Group.

Ann Oncol. 2015 Dec;26(12):2442-9. doi: 10.1093/annonc/mdv391. Epub 2015 Sep 19.


An International Multicenter Review of the Malignancy Rate of Excised Papillomatous Breast Lesions.

Foley NM, Racz JM, Al-Hilli Z, Livingstone V, Cil T, Holloway CM, Romics L Jr, Matrai Z, Bennett MW, Duddy L, Nofech-Mozes S, Slodkowska E, Mallon EA, Dawson N, Roche T, Relihan N, Hill AD, Redmond HP, Corrigan MA.

Ann Surg Oncol. 2015 Dec;22 Suppl 3:S385-90. doi: 10.1245/s10434-015-4773-z. Epub 2015 Aug 4.


Relative Effectiveness of Letrozole Compared With Tamoxifen for Patients With Lobular Carcinoma in the BIG 1-98 Trial.

Metzger Filho O, Giobbie-Hurder A, Mallon E, Gusterson B, Viale G, Winer EP, Thürlimann B, Gelber RD, Colleoni M, Ejlertsen B, Debled M, Price KN, Regan MM, Coates AS, Goldhirsch A.

J Clin Oncol. 2015 Sep 1;33(25):2772-9. doi: 10.1200/JCO.2015.60.8133. Epub 2015 Jul 27.


Allele specific expression in worker reproduction genes in the bumblebee Bombus terrestris.

Amarasinghe HE, Toghill BJ, Nathanael D, Mallon EB.

PeerJ. 2015 Jul 14;3:e1079. doi: 10.7717/peerj.1079. eCollection 2015.


Estrogen Receptor Expression in 21-Gene Recurrence Score Predicts Increased Late Recurrence for Estrogen-Positive/HER2-Negative Breast Cancer.

Dowsett M, Sestak I, Buus R, Lopez-Knowles E, Mallon E, Howell A, Forbes JF, Buzdar A, Cuzick J.

Clin Cancer Res. 2015 Jun 15;21(12):2763-70. doi: 10.1158/1078-0432.CCR-14-2842.


The potential role of DNA methylation in the pathogenesis of abdominal aortic aneurysm.

Toghill BJ, Saratzis A, Harrison SC, Verissimo AR, Mallon EB, Bown MJ.

Atherosclerosis. 2015 Jul;241(1):121-9. doi: 10.1016/j.atherosclerosis.2015.05.001. Epub 2015 May 7. Review.


Reproductive workers show queenlike gene expression in an intermediately eusocial insect, the buff-tailed bumble bee Bombus terrestris.

Harrison MC, Hammond RL, Mallon EB.

Mol Ecol. 2015 Jun;24(12):3043-63. doi: 10.1111/mec.13215. Epub 2015 May 26.


The genomes of two key bumblebee species with primitive eusocial organization.

Sadd BM, Barribeau SM, Bloch G, de Graaf DC, Dearden P, Elsik CG, Gadau J, Grimmelikhuijzen CJ, Hasselmann M, Lozier JD, Robertson HM, Smagghe G, Stolle E, Van Vaerenbergh M, Waterhouse RM, Bornberg-Bauer E, Klasberg S, Bennett AK, Câmara F, Guigó R, Hoff K, Mariotti M, Munoz-Torres M, Murphy T, Santesmasses D, Amdam GV, Beckers M, Beye M, Biewer M, Bitondi MM, Blaxter ML, Bourke AF, Brown MJ, Buechel SD, Cameron R, Cappelle K, Carolan JC, Christiaens O, Ciborowski KL, Clarke DF, Colgan TJ, Collins DH, Cridge AG, Dalmay T, Dreier S, du Plessis L, Duncan E, Erler S, Evans J, Falcon T, Flores K, Freitas FC, Fuchikawa T, Gempe T, Hartfelder K, Hauser F, Helbing S, Humann FC, Irvine F, Jermiin LS, Johnson CE, Johnson RM, Jones AK, Kadowaki T, Kidner JH, Koch V, Köhler A, Kraus FB, Lattorff HM, Leask M, Lockett GA, Mallon EB, Antonio DS, Marxer M, Meeus I, Moritz RF, Nair A, Näpflin K, Nissen I, Niu J, Nunes FM, Oakeshott JG, Osborne A, Otte M, Pinheiro DG, Rossié N, Rueppell O, Santos CG, Schmid-Hempel R, Schmitt BD, Schulte C, Simões ZL, Soares MP, Swevers L, Winnebeck EC, Wolschin F, Yu N, Zdobnov EM, Aqrawi PK, Blankenburg KP, Coyle M, Francisco L, Hernandez AG, Holder M, Hudson ME, Jackson L, Jayaseelan J, Joshi V, Kovar C, Lee SL, Mata R, Mathew T, Newsham IF, Ngo R, Okwuonu G, Pham C, Pu LL, Saada N, Santibanez J, Simmons D, Thornton R, Venkat A, Walden KK, Wu YQ, Debyser G, Devreese B, Asher C, Blommaert J, Chipman AD, Chittka L, Fouks B, Liu J, O'Neill MP, Sumner S, Puiu D, Qu J, Salzberg SL, Scherer SE, Muzny DM, Richards S, Robinson GE, Gibbs RA, Schmid-Hempel P, Worley KC.

Genome Biol. 2015 Apr 24;16:76. doi: 10.1186/s13059-015-0623-3.


Space-use behaviour of woodland caribou based on a cognitive movement model.

Avgar T, Baker JA, Brown GS, Hagens JS, Kittle AM, Mallon EE, McGreer MT, Mosser A, Newmaster SG, Patterson BR, Reid DE, Rodgers AR, Shuter J, Street GM, Thompson I, Turetsky MJ, Wiebe PA, Fryxell JM.

J Anim Ecol. 2015 Jul;84(4):1059-70. doi: 10.1111/1365-2656.12357. Epub 2015 Mar 20.


Differential gene expression and alternative splicing in insect immune specificity.

Riddell CE, Lobaton Garces JD, Adams S, Barribeau SM, Twell D, Mallon EB.

BMC Genomics. 2014 Nov 27;15:1031. doi: 10.1186/1471-2164-15-1031.


NEOCENT: a randomised feasibility and translational study comparing neoadjuvant endocrine therapy with chemotherapy in ER-rich postmenopausal primary breast cancer.

Palmieri C, Cleator S, Kilburn LS, Kim SB, Ahn SH, Beresford M, Gong G, Mansi J, Mallon E, Reed S, Mousa K, Fallowfield L, Cheang M, Morden J, Page K, Guttery DS, Rghebi B, Primrose L, Shaw JA, Thompson AM, Bliss JM, Coombes RC.

Breast Cancer Res Treat. 2014 Dec;148(3):581-90. doi: 10.1007/s10549-014-3183-4. Epub 2014 Nov 14.


Epidermal inclusion cyst following autologous breast reconstruction--an unusual cause of a breast lump.

Schaverien MV, Malyon AD, Mallon EA, Doughty JC.

Breast J. 2014 Sep-Oct;20(5):546-7. doi: 10.1111/tbj.12316. Epub 2014 Jul 12. No abstract available.


Expression of RUNX1 correlates with poor patient prognosis in triple negative breast cancer.

Ferrari N, Mohammed ZM, Nixon C, Mason SM, Mallon E, McMillan DC, Morris JS, Cameron ER, Edwards J, Blyth K.

PLoS One. 2014 Jun 26;9(6):e100759. doi: 10.1371/journal.pone.0100759. eCollection 2014.


Immune stimulation reduces sleep and memory ability in Drosophila melanogaster.

Mallon EB, Alghamdi A, Holdbrook RT, Rosato E.

PeerJ. 2014 Jun 10;2:e434. doi: 10.7717/peerj.434. eCollection 2014.


Methylation and worker reproduction in the bumble-bee (Bombus terrestris).

Amarasinghe HE, Clayton CI, Mallon EB.

Proc Biol Sci. 2014 Feb 12;281(1780):20132502. doi: 10.1098/rspb.2013.2502. Print 2014 Apr 7.


The relationship between lymphovascular invasion and angiogenesis, hormone receptors, cell proliferation and survival in patients with primary operable invasive ductal breast cancer.

Mohammed ZM, McMillan DC, Edwards J, Mallon E, Doughty JC, Orange C, Going JJ.

BMC Clin Pathol. 2013 Nov 25;13(1):31. doi: 10.1186/1472-6890-13-31.


SIRT2: tumour suppressor or tumour promoter in operable breast cancer?

McGlynn LM, Zino S, MacDonald AI, Curle J, Reilly JE, Mohammed ZM, McMillan DC, Mallon E, Payne AP, Edwards J, Shiels PG.

Eur J Cancer. 2014 Jan;50(2):290-301. doi: 10.1016/j.ejca.2013.10.005. Epub 2013 Oct 29.


Do type 1 receptor tyrosine kinases inform treatment choice? A prospectively planned analysis of the TEAM trial.

Bartlett JM, Brookes CL, Piper T, van de Velde CJ, Stocken D, Lyttle N, Hasenburg A, Quintayo MA, Kieback DG, Putter H, Markopoulos C, Kranenbarg EM, Mallon EA, Dirix LY, Seynaeve C, Rea DW.

Br J Cancer. 2013 Oct 29;109(9):2453-61. doi: 10.1038/bjc.2013.609. Epub 2013 Oct 3.


Antimicrobial peptides play a functional role in bumblebee anti-trypanosome defense.

Deshwal S, Mallon EB.

Dev Comp Immunol. 2014 Feb;42(2):240-3. doi: 10.1016/j.dci.2013.09.004. Epub 2013 Sep 20.


Probing the relationship between silicalite-1 defects and polyol adsorption properties.

Mallon EE, Jeon MY, Navarro M, Bhan A, Tsapatsis M.

Langmuir. 2013 Jun 4;29(22):6546-55. doi: 10.1021/la4001494. Epub 2013 May 21.


Comparison of visual and automated assessment of microvessel density and their impact on outcome in primary operable invasive ductal breast cancer.

Mohammed ZM, Orange C, McMillan DC, Mallon E, Doughty JC, Edwards J, Going JJ.

Hum Pathol. 2013 Aug;44(8):1688-95. doi: 10.1016/j.humpath.2012.11.023. Epub 2013 Apr 8.


Phosphorylation of AKT pathway proteins is not predictive of benefit of taxane therapy in early breast cancer.

Bartlett JM, A'hern R, Piper T, Ellis IO, Dowsett M, Mallon EA, Cameron DA, Johnston S, Bliss JM, Ellis P, Barrett-Lee PJ.

Breast Cancer Res Treat. 2013 Apr;138(3):773-81. doi: 10.1007/s10549-013-2489-y. Epub 2013 Mar 28.


Radiotherapy or tamoxifen after conserving surgery for breast cancers of excellent prognosis: British Association of Surgical Oncology (BASO) II trial.

Blamey RW, Bates T, Chetty U, Duffy SW, Ellis IO, George D, Mallon E, Mitchell MJ, Monypenny I, Morgan DA, Macmillan RD, Patnick J, Pinder SE.

Eur J Cancer. 2013 Jul;49(10):2294-302. doi: 10.1016/j.ejca.2013.02.031. Epub 2013 Mar 21.


Authors' reply.

Spears M, Cunningham CA, Taylor KJ, Mallon EA, Thomas JS, Kerr GR, Jack WJ, Kunkler IH, Cameron DA, Chetty U, Bartlett JM.

J Pathol. 2013 Feb;229(3):e2-3. doi: 10.1002/path.4144. No abstract available.


Comparison of visual and automated assessment of HER2 status and their impact on outcome in primary operable invasive ductal breast cancer.

Mohammed ZM, Going JJ, McMillan DC, Orange C, Mallon E, Doughty JC, Edwards J.

Histopathology. 2012 Oct;61(4):675-84. doi: 10.1111/j.1365-2559.2012.04280.x.


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