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Items: 33

1.

Zika virus alters DNA methylation status of genes involved in Hippo signaling pathway in human neural progenitor cells.

Kandilya D, Maskomani S, Shyamasundar S, Tambyah PA, Shiao Yng C, Lee RCH, Hande MP, Mallilankaraman K, Chu JJH, Dheen ST.

Epigenomics. 2019 Aug;11(10):1143-1161. doi: 10.2217/epi-2018-0180. Epub 2019 Jun 25.

PMID:
31234652
2.

Increased Akt-Driven Glycolysis Is the Basis for the Higher Potency of CD137L-DCs.

Zeng Q, Mallilankaraman K, Schwarz H.

Front Immunol. 2019 Apr 24;10:868. doi: 10.3389/fimmu.2019.00868. eCollection 2019.

3.

Negative Conditioning of Mitochondrial Dysfunction in Age-related Neurodegenerative Diseases.

Selvaraji S, Poh L, Natarajan V, Mallilankaraman K, Arumugam TV.

Cond Med. 2019 Feb;2(1):30-39.

4.

Microglial SMAD4 regulated by microRNA-146a promotes migration of microglia which support tumor progression in a glioma environment.

Karthikeyan A, Gupta N, Tang C, Mallilankaraman K, Silambarasan M, Shi M, Lu L, Ang BT, Ling EA, Dheen ST.

Oncotarget. 2018 May 18;9(38):24950-24969. doi: 10.18632/oncotarget.25116. eCollection 2018 May 18.

5.

Tissue-selective restriction of RNA editing of CaV1.3 by splicing factor SRSF9.

Huang H, Kapeli K, Jin W, Wong YP, Arumugam TV, Koh JH, Srimasorn S, Mallilankaraman K, Chua JJE, Yeo GW, Soong TW.

Nucleic Acids Res. 2018 Aug 21;46(14):7323-7338. doi: 10.1093/nar/gky348.

6.

Transcriptome analysis reveals intermittent fasting-induced genetic changes in ischemic stroke.

Kim J, Kang SW, Mallilankaraman K, Baik SH, Lim JC, Balaganapathy P, She DT, Lok KZ, Fann DY, Thambiayah U, Tang SC, Stranahan AM, Dheen ST, Gelderblom M, Seet RC, Karamyan VT, Vemuganti R, Sobey CG, Mattson MP, Jo DG, Arumugam TV.

Hum Mol Genet. 2018 Jul 1;27(13):2405. doi: 10.1093/hmg/ddy138. No abstract available.

7.

Transcriptome analysis reveals intermittent fasting-induced genetic changes in ischemic stroke.

Kim J, Kang SW, Mallilankaraman K, Baik SH, Lim JC, Balaganapathy P, She DT, Lok KZ, Fann DY, Thambiayah U, Tang SC, Stranahan AM, Dheen ST, Gelderblom M, Seet RC, Karamyan VT, Vemuganti R, Sobey CG, Mattson MP, Jo DG, Arumugam TV.

Hum Mol Genet. 2018 May 1;27(9):1497-1513. doi: 10.1093/hmg/ddy057. Erratum in: Hum Mol Genet. 2018 Jul 1;27(13):2405.

8.

Interplay between Notch and p53 promotes neuronal cell death in ischemic stroke.

Balaganapathy P, Baik SH, Mallilankaraman K, Sobey CG, Jo DG, Arumugam TV.

J Cereb Blood Flow Metab. 2018 Oct;38(10):1781-1795. doi: 10.1177/0271678X17715956. Epub 2017 Jun 15.

9.

EMRE Is a Matrix Ca(2+) Sensor that Governs Gatekeeping of the Mitochondrial Ca(2+) Uniporter.

Vais H, Mallilankaraman K, Mak DD, Hoff H, Payne R, Tanis JE, Foskett JK.

Cell Rep. 2016 Jan 26;14(3):403-410. doi: 10.1016/j.celrep.2015.12.054. Epub 2016 Jan 7.

10.

MCUR1, CCDC90A, Is a Regulator of the Mitochondrial Calcium Uniporter.

Vais H, Tanis JE, Müller M, Payne R, Mallilankaraman K, Foskett JK.

Cell Metab. 2015 Oct 6;22(4):533-5. doi: 10.1016/j.cmet.2015.09.015. No abstract available.

11.

MCUR1 is an essential component of mitochondrial Ca(2+) uptake that regulates cellular metabolism.

Mallilankaraman K, Cárdenas C, Doonan PJ, Chandramoorthy HC, Irrinki KM, Golenár T, Csordás G, Madireddi P, Yang J, Müller M, Miller R, Kolesar JE, Molgó J, Kaufman B, Hajnóczky G, Foskett JK, Madesh M.

Nat Cell Biol. 2015 Jul;17(7):953. doi: 10.1038/ncb3202. No abstract available.

PMID:
26123113
12.

Immunogenicity of a novel enhanced consensus DNA vaccine encoding the leptospiral protein LipL45.

Vijayachari P, Vedhagiri K, Mallilankaraman K, Mathur PP, Sardesai NY, Weiner DB, Ugen KE, Muthumani K.

Hum Vaccin Immunother. 2015;11(8):1945-53. doi: 10.1080/21645515.2015.1047117.

13.

Hyperhomocysteinemia and hyperglycemia induce and potentiate endothelial dysfunction via μ-calpain activation.

Cheng Z, Jiang X, Pansuria M, Fang P, Mai J, Mallilankaraman K, Gandhirajan RK, Eguchi S, Scalia R, Madesh M, Yang X, Wang H.

Diabetes. 2015 Mar;64(3):947-59. doi: 10.2337/db14-0784. Epub 2014 Oct 28.

14.

TRPM2 channels protect against cardiac ischemia-reperfusion injury: role of mitochondria.

Miller BA, Hoffman NE, Merali S, Zhang XQ, Wang J, Rajan S, Shanmughapriya S, Gao E, Barrero CA, Mallilankaraman K, Song J, Gu T, Hirschler-Laszkiewicz I, Koch WJ, Feldman AM, Madesh M, Cheung JY.

J Biol Chem. 2014 Mar 14;289(11):7615-29. doi: 10.1074/jbc.M113.533851. Epub 2014 Feb 3.

15.

MICU1 motifs define mitochondrial calcium uniporter binding and activity.

Hoffman NE, Chandramoorthy HC, Shamugapriya S, Zhang X, Rajan S, Mallilankaraman K, Gandhirajan RK, Vagnozzi RJ, Ferrer LM, Sreekrishnanilayam K, Natarajaseenivasan K, Vallem S, Force T, Choi ET, Cheung JY, Madesh M.

Cell Rep. 2013 Dec 26;5(6):1576-1588. doi: 10.1016/j.celrep.2013.11.026. Epub 2013 Dec 12.

16.

Inhibition of the cardiomyocyte-specific kinase TNNI3K limits oxidative stress, injury, and adverse remodeling in the ischemic heart.

Vagnozzi RJ, Gatto GJ Jr, Kallander LS, Hoffman NE, Mallilankaraman K, Ballard VL, Lawhorn BG, Stoy P, Philp J, Graves AP, Naito Y, Lepore JJ, Gao E, Madesh M, Force T.

Sci Transl Med. 2013 Oct 16;5(207):207ra141. doi: 10.1126/scitranslmed.3006479.

17.

Histone 3.3 participates in a self-sustaining cascade of apoptosis that contributes to the progression of chronic obstructive pulmonary disease.

Barrero CA, Perez-Leal O, Aksoy M, Moncada C, Ji R, Lopez Y, Mallilankaraman K, Madesh M, Criner GJ, Kelsen SG, Merali S.

Am J Respir Crit Care Med. 2013 Sep 15;188(6):673-83. doi: 10.1164/rccm.201302-0342OC.

18.

The second member of transient receptor potential-melastatin channel family protects hearts from ischemia-reperfusion injury.

Miller BA, Wang J, Hirschler-Laszkiewicz I, Gao E, Song J, Zhang XQ, Koch WJ, Madesh M, Mallilankaraman K, Gu T, Chen SJ, Keefer K, Conrad K, Feldman AM, Cheung JY.

Am J Physiol Heart Circ Physiol. 2013 Apr 1;304(7):H1010-22. doi: 10.1152/ajpheart.00906.2012. Epub 2013 Feb 1.

19.

Blockade of NOX2 and STIM1 signaling limits lipopolysaccharide-induced vascular inflammation.

Gandhirajan RK, Meng S, Chandramoorthy HC, Mallilankaraman K, Mancarella S, Gao H, Razmpour R, Yang XF, Houser SR, Chen J, Koch WJ, Wang H, Soboloff J, Gill DL, Madesh M.

J Clin Invest. 2013 Feb;123(2):887-902. doi: 10.1172/JCI65647. Epub 2013 Jan 25.

20.

Inflammasomes: sensors of metabolic stresses for vascular inflammation.

Yin Y, Pastrana JL, Li X, Huang X, Mallilankaraman K, Choi ET, Madesh M, Wang H, Yang XF.

Front Biosci (Landmark Ed). 2013 Jan 1;18:638-49. Review.

21.

MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism.

Mallilankaraman K, Cárdenas C, Doonan PJ, Chandramoorthy HC, Irrinki KM, Golenár T, Csordás G, Madireddi P, Yang J, Müller M, Miller R, Kolesar JE, Molgó J, Kaufman B, Hajnóczky G, Foskett JK, Madesh M.

Nat Cell Biol. 2012 Dec;14(12):1336-43. doi: 10.1038/ncb2622. Epub 2012 Nov 25. Erratum in: Nat Cell Biol. 2013 Jan;15(1):123. Nat Cell Biol. 2015 Jul;17(7):953.

22.

MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival.

Mallilankaraman K, Doonan P, Cárdenas C, Chandramoorthy HC, Müller M, Miller R, Hoffman NE, Gandhirajan RK, Molgó J, Birnbaum MJ, Rothberg BS, Mak DO, Foskett JK, Madesh M.

Cell. 2012 Oct 26;151(3):630-44. doi: 10.1016/j.cell.2012.10.011.

23.

Intracellular endothelin type B receptor-driven Ca2+ signal elicits nitric oxide production in endothelial cells.

Deliu E, Brailoiu GC, Mallilankaraman K, Wang H, Madesh M, Undieh AS, Koch WJ, Brailoiu E.

J Biol Chem. 2012 Nov 30;287(49):41023-31. doi: 10.1074/jbc.M112.418533. Epub 2012 Oct 19.

24.

Visualization of vascular Ca2+ signaling triggered by paracrine derived ROS.

Mallilankaraman K, Gandhirajan RK, Hawkins BJ, Madesh M.

J Vis Exp. 2011 Dec 21;(58). pii: 3511. doi: 10.3791/3511.

25.

Hypoxia-induced acidosis uncouples the STIM-Orai calcium signaling complex.

Mancarella S, Wang Y, Deng X, Landesberg G, Scalia R, Panettieri RA, Mallilankaraman K, Tang XD, Madesh M, Gill DL.

J Biol Chem. 2011 Dec 30;286(52):44788-98. doi: 10.1074/jbc.M111.303081. Epub 2011 Nov 14.

26.

Requirement of FADD, NEMO, and BAX/BAK for aberrant mitochondrial function in tumor necrosis factor alpha-induced necrosis.

Irrinki KM, Mallilankaraman K, Thapa RJ, Chandramoorthy HC, Smith FJ, Jog NR, Gandhirajan RK, Kelsen SG, Houser SR, May MJ, Balachandran S, Madesh M.

Mol Cell Biol. 2011 Sep;31(18):3745-58. doi: 10.1128/MCB.05303-11. Epub 2011 Jul 11.

27.

Hyperhomocysteinemia impairs endothelium-derived hyperpolarizing factor-mediated vasorelaxation in transgenic cystathionine beta synthase-deficient mice.

Cheng Z, Jiang X, Kruger WD, Praticò D, Gupta S, Mallilankaraman K, Madesh M, Schafer AI, Durante W, Yang X, Wang H.

Blood. 2011 Aug 18;118(7):1998-2006. doi: 10.1182/blood-2011-01-333310. Epub 2011 Jun 8.

28.

NF-kappaB protects cells from gamma interferon-induced RIP1-dependent necroptosis.

Thapa RJ, Basagoudanavar SH, Nogusa S, Irrinki K, Mallilankaraman K, Slifker MJ, Beg AA, Madesh M, Balachandran S.

Mol Cell Biol. 2011 Jul;31(14):2934-46. doi: 10.1128/MCB.05445-11. Epub 2011 May 16.

29.

A DNA vaccine against chikungunya virus is protective in mice and induces neutralizing antibodies in mice and nonhuman primates.

Mallilankaraman K, Shedlock DJ, Bao H, Kawalekar OU, Fagone P, Ramanathan AA, Ferraro B, Stabenow J, Vijayachari P, Sundaram SG, Muruganandam N, Sarangan G, Srikanth P, Khan AS, Lewis MG, Kim JJ, Sardesai NY, Muthumani K, Weiner DB.

PLoS Negl Trop Dis. 2011 Jan 11;5(1):e928. doi: 10.1371/journal.pntd.0000928.

30.

A highly optimized DNA vaccine confers complete protective immunity against high-dose lethal lymphocytic choriomeningitis virus challenge.

Shedlock DJ, Talbott KT, Cress C, Ferraro B, Tuyishme S, Mallilankaraman K, Cisper NJ, Morrow MP, Wu SJ, Kawalekar OU, Khan AS, Sardesai NY, Muthumani K, Shen H, Weiner DB.

Vaccine. 2011 Sep 9;29(39):6755-62. doi: 10.1016/j.vaccine.2010.12.064. Epub 2011 Jan 14.

31.

Molecular characterization of Chikungunya virus during an outbreak in South India.

Srikanth P, Sarangan G, Mallilankaraman K, Nayar SA, Barani R, Mattew T, Selvaraj GF, Sheriff KA, Palani G, Muthumani K.

Indian J Med Microbiol. 2010 Oct-Dec;28(4):299-302. doi: 10.4103/0255-0857.71812.

32.

S-glutathionylation activates STIM1 and alters mitochondrial homeostasis.

Hawkins BJ, Irrinki KM, Mallilankaraman K, Lien YC, Wang Y, Bhanumathy CD, Subbiah R, Ritchie MF, Soboloff J, Baba Y, Kurosaki T, Joseph SK, Gill DL, Madesh M.

J Cell Biol. 2010 Aug 9;190(3):391-405. doi: 10.1083/jcb.201004152. Epub 2010 Aug 2.

33.

HIV-1 Vpr: regulator of viral survival.

Thieu KP, Morrow MP, Shedlock DJ, Schoenly KA, Mallilankaraman K, Choo AY, Fagone P, Weiner DB, Muthumani K.

Curr HIV Res. 2009 Mar;7(2):153-62. Review.

PMID:
19275584

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