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Items: 36

1.

Efficacy and safety of dihydroartemisinin-piperaquine for treatment of Plasmodium falciparum uncomplicated malaria in adult patients on antiretroviral therapy in Malawi and Mozambique: an open label non-randomized interventional trial.

Sevene E, Banda CG, Mukaka M, Maculuve S, Macuacua S, Vala A, Piqueras M, Kalilani-Phiri L, Mallewa J, Terlouw DJ, Khoo SH, Lalloo DG, Mwapasa V.

Malar J. 2019 Aug 20;18(1):277. doi: 10.1186/s12936-019-2909-5.

2.

HIV-Related Arterial Stiffness in Malawian Adults Is Associated With the Proportion of PD-1-Expressing CD8+ T Cells and Reverses With Antiretroviral Therapy.

Kelly C, Mwandumba HC, Heyderman RS, Jambo K, Kamng'ona R, Chammudzi M, Sheha I, Peterson I, Rapala A, Mallewa J, Walker AS, Klein N, Khoo S.

J Infect Dis. 2019 May 24;219(12):1948-1958. doi: 10.1093/infdis/jiz015.

3.

Etiology and Risk Factors for Mortality in an Adult Community-acquired Pneumonia Cohort in Malawi.

Aston SJ, Ho A, Jary H, Huwa J, Mitchell T, Ibitoye S, Greenwood S, Joekes E, Daire A, Mallewa J, Everett D, Nyirenda M, Faragher B, Mwandumba HC, Heyderman RS, Gordon SB.

Am J Respir Crit Care Med. 2019 Aug 1;200(3):359-369. doi: 10.1164/rccm.201807-1333OC.

4.

Five-year single-centre experience of carcinoma of the oesophagus from Blantyre, Malawi.

Chetwood JD, Finch PJ, Kankwatira A, Mallewa J, Gordon MA, Masamba L.

BMJ Open Gastroenterol. 2018 Oct 15;5(1):e000232. doi: 10.1136/bmjgast-2018-000232. eCollection 2018. Erratum in: BMJ Open Gastroenterol. 2018 Dec 30;5(1):e000232corr1.

5.

HIV infection has a profound effect on hematological factors but not on electrolyte profile of Malawian adults presenting with uncomplicated malaria and severe malaria.

Munyenyembe AU, Gausi K, Nyirenda TS, Hiestand J, Mallewa J, Mandala WL.

J Blood Med. 2018 Oct 4;9:153-162. doi: 10.2147/JBM.S172869. eCollection 2018.

6.

Impact of Efavirenz-, Ritonavir-Boosted Lopinavir-, and Nevirapine-Based Antiretroviral Regimens on the Pharmacokinetics of Lumefantrine and Safety of Artemether-Lumefantrine in Plasmodium falciparum-Negative HIV-Infected Malawian Adults Stabilized on Antiretroviral Therapy.

Banda CG, Dzinjalamala F, Mukaka M, Mallewa J, Maiden V, Terlouw DJ, Lalloo DG, Khoo SH, Mwapasa V.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e01162-18. doi: 10.1128/AAC.01162-18. Print 2018 Nov.

7.

Epidemiology of Severe Acute Respiratory Illness and Risk Factors for Influenza Infection and Clinical Severity among Adults in Malawi, 2011-2013.

Ho A, Mallewa J, Peterson I, SanJoaquin M, Garg S, Bar-Zeev N, Menyere M, Alaerts M, Mapurisa G, Chilombe M, Nyirenda M, Lalloo DG, Rothe C, Widdowson MA, McMorrow M, French N, Everett D, Heyderman RS.

Am J Trop Med Hyg. 2018 Sep;99(3):772-779. doi: 10.4269/ajtmh.17-0905. Epub 2018 Jul 19.

8.

Pharmacokinetics of Piperaquine and Safety Profile of Dihydroartemisinin-Piperaquine Coadministered with Antiretroviral Therapy in Malaria-Uninfected HIV-Positive Malawian Adults.

Banda CG, Dzinjalamala F, Mukaka M, Mallewa J, Maiden V, Terlouw DJ, Lalloo DG, Khoo SH, Mwapasa V.

Antimicrob Agents Chemother. 2018 Jul 27;62(8). pii: e00634-18. doi: 10.1128/AAC.00634-18. Print 2018 Aug.

9.

Pharmacokinetics and Safety Profile of Artesunate-Amodiaquine Coadministered with Antiretroviral Therapy in Malaria-Uninfected HIV-Positive Malawian Adults.

Banda CG, Dzinjalamala F, Mukaka M, Mallewa J, Maiden V, Terlouw DJ, Lalloo DG, Khoo SH, Mwapasa V.

Antimicrob Agents Chemother. 2018 Jun 26;62(7). pii: e00412-18. doi: 10.1128/AAC.00412-18. Print 2018 Jul.

10.

Effect of ready-to-use supplementary food on mortality in severely immunocompromised HIV-infected individuals in Africa initiating antiretroviral therapy (REALITY): an open-label, parallel-group, randomised controlled trial.

Mallewa J, Szubert AJ, Mugyenyi P, Chidziva E, Thomason MJ, Chepkorir P, Abongomera G, Baleeta K, Etyang A, Warambwa C, Melly B, Mudzingwa S, Kelly C, Agutu C, Wilkes H, Nkomani S, Musiime V, Lugemwa A, Pett SL, Bwakura-Dangarembizi M, Prendergast AJ, Gibb DM, Walker AS, Berkley JA; REALITY trial team.

Lancet HIV. 2018 May;5(5):e231-e240. doi: 10.1016/S2352-3018(18)30038-9. Epub 2018 Apr 10. Erratum in: Lancet HIV. 2018 Jul;5(7):e340.

11.

Late Presentation With HIV in Africa: Phenotypes, Risk, and Risk Stratification in the REALITY Trial.

Siika A, McCabe L, Bwakura-Dangarembizi M, Kityo C, Mallewa J, Berkley J, Maitland K, Griffiths A, Baleeta K, Mudzingwa S, Abach J, Nathoo K, Thomason MJ, Prendergast AJ, Walker AS, Gibb DM; REALITY Trial Team .

Clin Infect Dis. 2018 Mar 4;66(suppl_2):S140-S146. doi: 10.1093/cid/cix1142.

12.

Causes and Timing of Mortality and Morbidity Among Late Presenters Starting Antiretroviral Therapy in the REALITY Trial.

Post FA, Szubert AJ, Prendergast AJ, Johnston V, Lyall H, Fitzgerald F, Musiime V, Musoro G, Chepkorir P, Agutu C, Mallewa J, Rajapakse C, Wilkes H, Hakim J, Mugyenyi P, Walker AS, Gibb DM, Pett SL; Reduction of EArly mortaLITY in HIV-infected adults and children starting antiretroviral therapy (REALITY) Trial Team .

Clin Infect Dis. 2018 Mar 4;66(suppl_2):S132-S139. doi: 10.1093/cid/cix1141.

13.

A targeted approach for routine viral load monitoring in Malawian adults on antiretroviral therapy.

Mungwira RG, Divala TH, Nyirenda OM, Kanjala M, Muwalo F, Mkandawire FA, Choko A, Taylor TE, Mallewa J, van Oosterhout JJ, Laufer MK, Laurens MB.

Trop Med Int Health. 2018 May;23(5):526-532. doi: 10.1111/tmi.13047. Epub 2018 Mar 30.

14.

Household air pollution, chronic respiratory disease and pneumonia in Malawian adults: A case-control study.

Jary HR, Aston S, Ho A, Giorgi E, Kalata N, Nyirenda M, Mallewa J, Peterson I, Gordon SB, Mortimer K.

Wellcome Open Res. 2017 Oct 24;2:103. doi: 10.12688/wellcomeopenres.12621.1. eCollection 2017.

15.

Impact of Human Immunodeficiency Virus on the Burden and Severity of Influenza Illness in Malawian Adults: A Prospective Cohort and Parallel Case-Control Study.

Ho A, Aston SJ, Jary H, Mitchell T, Alaerts M, Menyere M, Mallewa J, Nyirenda M, Everett D, Heyderman RS, French N.

Clin Infect Dis. 2018 Mar 5;66(6):865-876. doi: 10.1093/cid/cix903.

16.

Challenges of stroke management in resource-limited settings: A case-based reflection.

Gadama YG, Mwangalika G, Kinley LB, Jackson B, Mwandumba HC, Mallewa J, Solomon T, Simister R, Benjamin LA, Vargas MI, Kamtchum-Tatuene J, Phiri T.

Malawi Med J. 2017 Jun;29(2):189-193.

17.

Trends in antimicrobial resistance in bloodstream infection isolates at a large urban hospital in Malawi (1998-2016): a surveillance study.

Musicha P, Cornick JE, Bar-Zeev N, French N, Masesa C, Denis B, Kennedy N, Mallewa J, Gordon MA, Msefula CL, Heyderman RS, Everett DB, Feasey NA.

Lancet Infect Dis. 2017 Oct;17(10):1042-1052. doi: 10.1016/S1473-3099(17)30394-8. Epub 2017 Aug 14.

18.

Enhanced Prophylaxis plus Antiretroviral Therapy for Advanced HIV Infection in Africa.

Hakim J, Musiime V, Szubert AJ, Mallewa J, Siika A, Agutu C, Walker S, Pett SL, Bwakura-Dangarembizi M, Lugemwa A, Kaunda S, Karoney M, Musoro G, Kabahenda S, Nathoo K, Maitland K, Griffiths A, Thomason MJ, Kityo C, Mugyenyi P, Prendergast AJ, Walker AS, Gibb DM; REALITY Trial Team.

N Engl J Med. 2017 Jul 20;377(3):233-245. doi: 10.1056/NEJMoa1615822.

19.

Frequent malaria illness episodes in two Malawian patients on antiretroviral therapy soon after stopping cotrimoxazole preventive therapy.

Nyangulu WJ, Mwinjiwa E, Divala TH, Mungwira RG, Nyirenda O, Kanjala M, Mbambo G, Mallewa J, Taylor TE, Laurens MB, Laufer MK, van Oosterhout JJ.

Malawi Med J. 2017 Mar;29(1):57-60.

20.

The burden of hypertension, diabetes mellitus, and cardiovascular risk factors among adult Malawians in HIV care: consequences for integrated services.

Divala OH, Amberbir A, Ismail Z, Beyene T, Garone D, Pfaff C, Singano V, Akello H, Joshua M, Nyirenda MJ, Matengeni A, Berman J, Mallewa J, Chinomba GS, Kayange N, Allain TJ, Chan AK, Sodhi SK, van Oosterhout JJ.

BMC Public Health. 2016 Dec 12;16(1):1243.

21.

TSCQ study: a randomized, controlled, open-label trial of daily trimethoprim-sulfamethoxazole or weekly chloroquine among adults on antiretroviral therapy in Malawi: study protocol for a randomized controlled trial.

Laurens MB, Mungwira RG, Nyirenda OM, Divala TH, Kanjala M, Muwalo F, Mkandawire FA, Tsirizani L, Nyangulu W, Mwinjiwa E, Taylor TE, Mallewa J, Blackwelder WC, Plowe CV, Laufer MK, van Oosterhout JJ.

Trials. 2016 Jul 18;17(1):322. doi: 10.1186/s13063-016-1392-3.

22.

Unstructured treatment interruption: an important risk factor for arterial stiffness in adult Malawian patients with antiretroviral treatment.

Peterson I, Ming D, Kelly C, Malisita K, Mallewa J, Mwandumba HC, Lalloo DG, Heyderman RS.

AIDS. 2016 Sep 24;30(15):2373-8. doi: 10.1097/QAD.0000000000001198.

PMID:
27428743
23.

Challenges with targeted viral load testing for medical inpatients at Queen Elizabeth Central Hospital in Blantyre, Malawi.

Craik A, Patel P, Patel P, Mallewa J, Malisita K, Bitilinyu-Bangoh J, van Oosterhout JJ, Kelly C.

Malawi Med J. 2016 Dec;28(4):179-181.

24.

Three Epidemics of Invasive Multidrug-Resistant Salmonella Bloodstream Infection in Blantyre, Malawi, 1998-2014.

Feasey NA, Masesa C, Jassi C, Faragher EB, Mallewa J, Mallewa M, MacLennan CA, Msefula C, Heyderman RS, Gordon MA.

Clin Infect Dis. 2015 Nov 1;61 Suppl 4:S363-71. doi: 10.1093/cid/civ691.

25.

Mathematical Modeling to Assess the Drivers of the Recent Emergence of Typhoid Fever in Blantyre, Malawi.

Pitzer VE, Feasey NA, Msefula C, Mallewa J, Kennedy N, Dube Q, Denis B, Gordon MA, Heyderman RS.

Clin Infect Dis. 2015 Nov 1;61 Suppl 4:S251-8. doi: 10.1093/cid/civ710.

26.

Study protocol: the effects of air pollution exposure and chronic respiratory disease on pneumonia risk in urban Malawian adults--the Acute Infection of the Respiratory Tract Study (The AIR Study).

Jary H, Mallewa J, Nyirenda M, Faragher B, Heyderman R, Peterson I, Gordon S, Mortimer K.

BMC Pulm Med. 2015 Aug 20;15:96. doi: 10.1186/s12890-015-0090-3.

27.

Lumbar puncture refusal in sub-Saharan Africa: A call for further understanding and intervention.

Thakur KT, Mateyo K, Hachaambwa L, Kayamba V, Mallewa M, Mallewa J, Nwazor EO, Lawal T, Mallum CB, Atadzhanov M, Boulware DR, Birbeck GL, Siddiqi OK.

Neurology. 2015 May 12;84(19):1988-90. doi: 10.1212/WNL.0000000000001561. No abstract available.

28.

Rapid emergence of multidrug resistant, H58-lineage Salmonella typhi in Blantyre, Malawi.

Feasey NA, Gaskell K, Wong V, Msefula C, Selemani G, Kumwenda S, Allain TJ, Mallewa J, Kennedy N, Bennett A, Nyirongo JO, Nyondo PA, Zulu MD, Parkhill J, Dougan G, Gordon MA, Heyderman RS.

PLoS Negl Trop Dis. 2015 Apr 24;9(4):e0003748. doi: 10.1371/journal.pntd.0003748. eCollection 2015 Apr.

29.

Severe toxicity and polymerase-γ gene abnormalities in Malawian adults on stavudine-based antiretroviral therapy.

van Oosterhout JJ, Gardner K, Mallewa J, Kaunda S, Kampira E, Payne B, Heyderman RS, Chinnery P.

Pharmacogenet Genomics. 2013 Nov;23(11):624-6. doi: 10.1097/FPC.0b013e3283655053.

PMID:
23962909
30.

Longitudinal lactate levels from routine point-of-care monitoring in adult Malawian antiretroviral therapy patients: associations with stavudine toxicities.

Chagoma N, Mallewa J, Kaunda S, Njalale Y, Kampira E, Mukaka M, Heyderman RS, van Oosterhout JJ.

Trans R Soc Trop Med Hyg. 2013 Oct;107(10):615-9. doi: 10.1093/trstmh/trt074. Epub 2013 Aug 7.

31.

Stavudine toxicity in adult longer-term ART patients in Blantyre, Malawi.

van Oosterhout JJ, Mallewa J, Kaunda S, Chagoma N, Njalale Y, Kampira E, Mukaka M, Heyderman RS.

PLoS One. 2012;7(7):e42029. doi: 10.1371/journal.pone.0042029. Epub 2012 Jul 26.

32.

Ward round--A patient with multi-organ failure.

Stevenson A, Phiri C, Mallewa J, Molyneux M.

Malawi Med J. 2011 Mar;23(1):16-7. No abstract available.

33.

Cardiovascular disease risk management in HIV patients, experiences from Greater Manchester.

Mallewa JE, Higgins SP, Garbett S, Saxena N, Vilar FJ.

Int J STD AIDS. 2009 Jun;20(6):425-6. doi: 10.1258/ijsa.2008.008295.

PMID:
19451331
34.

HIV-associated lipodystrophy: a review of underlying mechanisms and therapeutic options.

Mallewa JE, Wilkins E, Vilar J, Mallewa M, Doran D, Back D, Pirmohamed M.

J Antimicrob Chemother. 2008 Oct;62(4):648-60. doi: 10.1093/jac/dkn251. Epub 2008 Jun 18. Review.

PMID:
18565973
35.

Evaluation of antiretroviral therapy results in Blantyre, Malawi.

van Oosterhout JJ, Bodasing N, Kumwenda JJ, Nyirenda C, Mallewa J, Cleary PR, de Baar MP, Schuurman R, Burger DM, Zijlstra EE.

Malawi Med J. 2005 Dec;17(4):112-6.

36.

Evaluation of antiretroviral therapy results in a resource-poor setting in Blantyre, Malawi.

van Oosterhout JJ, Bodasing N, Kumwenda JJ, Nyirenda C, Mallewa J, Cleary PR, de Baar MP, Schuurman R, Burger DM, Zijlstra EE.

Trop Med Int Health. 2005 May;10(5):464-70.

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