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Corrigendum: depletion of tumor-associated macrophages slows the growth of chemically induced mouse lung adenocarcinomas.

Fritz JM, Tennis MA, Orlicky DJ, Yin H, Ju C, Redente EF, Choo KS, Staab TA, Bouchard RJ, Merrick DT, Malkinson AM, Dwyer-Nield LD.

Front Immunol. 2015 Mar 3;6:88. doi: 10.3389/fimmu.2015.00088. eCollection 2015.


Depletion of tumor-associated macrophages slows the growth of chemically induced mouse lung adenocarcinomas.

Fritz JM, Tennis MA, Orlicky DJ, Lin H, Ju C, Redente EF, Choo KS, Staab TA, Bouchard RJ, Merrick DT, Malkinson AM, Dwyer-Nield LD.

Front Immunol. 2014 Nov 25;5:587. doi: 10.3389/fimmu.2014.00587. eCollection 2014. Erratum in: Front Immunol. 2015;6:88.


Silibinin modulates TNF-α and IFN-γ mediated signaling to regulate COX2 and iNOS expression in tumorigenic mouse lung epithelial LM2 cells.

Tyagi A, Agarwal C, Dwyer-Nield LD, Singh RP, Malkinson AM, Agarwal R.

Mol Carcinog. 2012 Oct;51(10):832-42. doi: 10.1002/mc.20851. Epub 2011 Aug 31.


BARD1: an independent predictor of survival in non-small cell lung cancer.

Zhang YQ, Bianco A, Malkinson AM, Leoni VP, Frau G, De Rosa N, André PA, Versace R, Boulvain M, Laurent GJ, Atzori L, Irminger-Finger I.

Int J Cancer. 2012 Jul 1;131(1):83-94. doi: 10.1002/ijc.26346. Epub 2011 Dec 21.


Silibinin prevents lung tumorigenesis in wild-type but not in iNOS-/- mice: potential of real-time micro-CT in lung cancer chemoprevention studies.

Ramasamy K, Dwyer-Nield LD, Serkova NJ, Hasebroock KM, Tyagi A, Raina K, Singh RP, Malkinson AM, Agarwal R.

Clin Cancer Res. 2011 Feb 15;17(4):753-61. doi: 10.1158/1078-0432.CCR-10-2290. Epub 2010 Dec 10.


Regulation of cytokine-induced prostanoid and nitric oxide synthesis by extracellular signal–regulated kinase 1/2 in lung epithelial cells.

Rice PL, Barrett BS, Fritz JM, Srebernak MC, Kisley LR, Malkinson AM, Dwyer-Nield LD.

Exp Lung Res. 2010 Nov;36(9):558-71. doi: 10.3109/01902148.2010.491891.


Tumor progression stage and anatomical site regulate tumor-associated macrophage and bone marrow-derived monocyte polarization.

Redente EF, Dwyer-Nield LD, Merrick DT, Raina K, Agarwal R, Pao W, Rice PL, Shroyer KR, Malkinson AM.

Am J Pathol. 2010 Jun;176(6):2972-85. doi: 10.2353/ajpath.2010.090879. Epub 2010 Apr 29.


Differential polarization of alveolar macrophages and bone marrow-derived monocytes following chemically and pathogen-induced chronic lung inflammation.

Redente EF, Higgins DM, Dwyer-Nield LD, Orme IM, Gonzalez-Juarrero M, Malkinson AM.

J Leukoc Biol. 2010 Jul;88(1):159-68. doi: 10.1189/jlb.0609378. Epub 2010 Apr 1.


The Kras mutational spectra of chemically induced lung tumors in different inbred mice mimics the spectra of KRAS mutations in adenocarcinomas in smokers versus nonsmokers.

Fritz JM, Dwyer-Nield LD, Russell BM, Malkinson AM.

J Thorac Oncol. 2010 Feb;5(2):254-7. doi: 10.1097/JTO.0b013e3181c8ce04.


Lung tumor growth is stimulated in IFN-gamma-/- mice and inhibited in IL-4Ralpha-/- mice.

Redente EF, Dwyer-Nield LD, Barrett BS, Riches DW, Malkinson AM.

Anticancer Res. 2009 Dec;29(12):5095-101.


Clara cell: progenitor for the bronchiolar epithelium.

Reynolds SD, Malkinson AM.

Int J Biochem Cell Biol. 2010 Jan;42(1):1-4. doi: 10.1016/j.biocel.2009.09.002. Epub 2009 Sep 9. Review.


Epistatic interactions govern chemically-induced lung tumor susceptibility and Kras mutation site in murine C57BL/6J-ChrA/J chromosome substitution strains.

Dwyer-Nield LD, McQuillan J, Hill-Baskin A, Radcliffe RA, You M, Nadeau JH, Malkinson AM.

Int J Cancer. 2010 Jan 1;126(1):125-32. doi: 10.1002/ijc.24743.


Growth inhibition and regression of lung tumors by silibinin: modulation of angiogenesis by macrophage-associated cytokines and nuclear factor-kappaB and signal transducers and activators of transcription 3.

Tyagi A, Singh RP, Ramasamy K, Raina K, Redente EF, Dwyer-Nield LD, Radcliffe RA, Malkinson AM, Agarwal R.

Cancer Prev Res (Phila). 2009 Jan;2(1):74-83. doi: 10.1158/1940-6207.CAPR-08-0095.


Misexpression of MIA disrupts lung morphogenesis and causes neonatal death.

Lin S, Ikegami M, Xu Y, Bosserhoff AK, Malkinson AM, Shannon JM.

Dev Biol. 2008 Apr 15;316(2):441-55. doi: 10.1016/j.ydbio.2008.02.003. Epub 2008 Feb 15.


A macrophage gene expression signature defines a field effect in the lung tumor microenvironment.

Stearman RS, Dwyer-Nield L, Grady MC, Malkinson AM, Geraci MW.

Cancer Res. 2008 Jan 1;68(1):34-43. doi: 10.1158/0008-5472.CAN-07-0988.


Inhibition by erlotinib of primary lung adenocarcinoma at an early stage in male mice.

Zerbe LK, Dwyer-Nield LD, Fritz JM, Redente EF, Shroyer RJ, Conklin E, Kane S, Tucker C, Eckhardt SG, Gustafson DL, Iwata KK, Malkinson AM.

Cancer Chemother Pharmacol. 2008 Sep;62(4):605-20. Epub 2007 Nov 21.


Altered expression of splicing factor, heterogeneous nuclear ribonucleoprotein A2/B1, in mouse lung neoplasia.

Peebles KA, Dwyer-Nield LD, Malkinson AM.

Mol Carcinog. 2007 Nov;46(11):887-900.


BAC consensus conference, November 4-6, 2004: epidemiology, pathogenesis, and preclinical models.

Christiani DC, Pao W, DeMartini JC, Linnoila RI, Malkinson AM, Onn A, Politi KA, Sharp M, Wong KK.

J Thorac Oncol. 2006 Nov;1(9 Suppl):S2-7. Erratum in: J Thorac Oncol. 2007 Jan;2(1):11. Kim, Kwok [corrected to Wong, Kwok-Kin].


Prostaglandin E2 receptor subtype 2 (EP2) null mice are protected against murine lung tumorigenesis.

Keith RL, Geraci MW, Nana-Sinkam SP, Breyer RM, Hudish TM, Meyer AM, Malkinson AM, Dwyer-Nield LD.

Anticancer Res. 2006 Jul-Aug;26(4B):2857-61.


Effect of silibinin on the growth and progression of primary lung tumors in mice.

Singh RP, Deep G, Chittezhath M, Kaur M, Dwyer-Nield LD, Malkinson AM, Agarwal R.

J Natl Cancer Inst. 2006 Jun 21;98(12):846-55.


Attenuation of the pulmonary inflammatory response following butylated hydroxytoluene treatment of cytosolic phospholipase A2 null mice.

Meyer AM, Dwyer-Nield LD, Hurteau G, Keith RL, Ouyang Y, Freed BM, Kisley LR, Geraci MW, Bonventre JV, Nemenoff RA, Malkinson AM.

Am J Physiol Lung Cell Mol Physiol. 2006 Jun;290(6):L1260-6. Epub 2006 Jan 27.


Quantitative analysis of early chemically-induced pulmonary lesions in mice of varying susceptibilities to lung tumorigenesis.

O'Donnell EP, Zerbe LK, Dwyer-Nield LD, Kisley LR, Malkinson AM.

Cancer Lett. 2006 Sep 28;241(2):197-202. Epub 2005 Dec 7.


Toll-like receptor 4 in butylated hydroxytoluene-induced mouse pulmonary inflammation and tumorigenesis.

Bauer AK, Dixon D, DeGraff LM, Cho HY, Walker CR, Malkinson AM, Kleeberger SR.

J Natl Cancer Inst. 2005 Dec 7;97(23):1778-81.


Analysis of orthologous gene expression between human pulmonary adenocarcinoma and a carcinogen-induced murine model.

Stearman RS, Dwyer-Nield L, Zerbe L, Blaine SA, Chan Z, Bunn PA Jr, Johnson GL, Hirsch FR, Merrick DT, Franklin WA, Baron AE, Keith RL, Nemenoff RA, Malkinson AM, Geraci MW.

Am J Pathol. 2005 Dec;167(6):1763-75.


Role of inflammation in mouse lung tumorigenesis: a review.

Malkinson AM.

Exp Lung Res. 2005 Jan-Feb;31(1):57-82. Review.


Cytokines differentially regulate the synthesis of prostanoid and nitric oxide mediators in tumorigenic versus non-tumorigenic mouse lung epithelial cell lines.

Dwyer-Nield LD, Srebernak MC, Barrett BS, Ahn J, Cosper P, Meyer AM, Kisley LR, Bauer AK, Thompson DC, Malkinson AM.

Carcinogenesis. 2005 Jul;26(7):1196-206. Epub 2005 Mar 3.


Relative amounts of antagonistic splicing factors, hnRNP A1 and ASF/SF2, change during neoplastic lung growth: implications for pre-mRNA processing.

Zerbe LK, Pino I, Pio R, Cosper PF, Dwyer-Nield LD, Meyer AM, Port JD, Montuenga LM, Malkinson AM.

Mol Carcinog. 2004 Dec;41(4):187-96.


Susceptibility to neoplastic and non-neoplastic pulmonary diseases in mice: genetic similarities.

Bauer AK, Malkinson AM, Kleeberger SR.

Am J Physiol Lung Cell Mol Physiol. 2004 Oct;287(4):L685-703. Review.


Mutation-selective tumor remission with Ras-targeted, whole yeast-based immunotherapy.

Lu Y, Bellgrau D, Dwyer-Nield LD, Malkinson AM, Duke RC, Rodell TC, Franzusoff A.

Cancer Res. 2004 Aug 1;64(15):5084-8.


Evidence that inflammation encourages pulmonary adenocarcinoma formation in mice: clinical implications.

Malkinson AM.

Chest. 2004 May;125(5 Suppl):154S-5S. No abstract available.


Serum levels of surfactant protein D are increased in mice with lung tumors.

Zhang F, Pao W, Umphress S, Jakowlew S, Meyer AM, Dwyer-Nield LD, Takeda K, Gelfand EW, Fisher J, Malkinson AM, Mason RJ.

Chest. 2004 May;125(5 Suppl):109S. No abstract available.


Decreased lung tumorigenesis in mice genetically deficient in cytosolic phospholipase A2.

Meyer AM, Dwyer-Nield LD, Hurteau GJ, Keith RL, O'Leary E, You M, Bonventre JV, Nemenoff RA, Malkinson AM.

Carcinogenesis. 2004 Aug;25(8):1517-24. Epub 2004 Mar 19.


Tnfa and Il-10 deficiencies have contrasting effects on lung tumor susceptibility: gender-dependent modulation of IL-10 haploinsufficiency.

Bernert H, Sekikawa K, Radcliffe RA, Iraqi F, You M, Malkinson AM.

Mol Carcinog. 2003 Nov;38(3):117-23.


Serum levels of surfactant protein D are increased in mice with lung tumors.

Zhang F, Pao W, Umphress SM, Jakowlew SB, Meyer AM, Dwyer-Nield LD, Nielsen LD, Takeda K, Gelfand EW, Fisher JH, Zhang L, Malkinson AM, Mason RJ.

Cancer Res. 2003 Sep 15;63(18):5889-94.


Induction of a high incidence of lung tumors in C57BL/6 mice with multiple ethyl carbamate injections.

Miller YE, Dwyer-Nield LD, Keith RL, Le M, Franklin WA, Malkinson AM.

Cancer Lett. 2003 Aug 20;198(2):139-44.


Fine mapping and identification of candidate pulmonary adenoma susceptibility 1 genes using advanced intercross lines.

Wang M, Lemon WJ, Liu G, Wang Y, Iraqi FA, Malkinson AM, You M.

Cancer Res. 2003 Jun 15;63(12):3317-24.


Responses of tumorigenic and non-tumorigenic mouse lung epithelial cell lines to electrophilic metabolites of the tumor promoter butylated hydroxytoluene.

Sun Y, Dwyer-Nield LD, Malkinson AM, Zhang YL, Thompson JA.

Chem Biol Interact. 2003 Mar 6;145(1):41-51.


Gap junctional intercellular communication in cells isolated from urethane-induced tumors in A/J mice.

Vultur A, Tomai E, Peebles K, Malkinson AM, Grammatikakis N, Forkert PG, Raptis L.

DNA Cell Biol. 2003 Jan;22(1):33-40.


Genetic ablation of inducible nitric oxide synthase decreases mouse lung tumorigenesis.

Kisley LR, Barrett BS, Bauer AK, Dwyer-Nield LD, Barthel B, Meyer AM, Thompson DC, Malkinson AM.

Cancer Res. 2002 Dec 1;62(23):6850-6.


Morphological assessment of apoptosis in human lung cells.

Dwyer-Nield LD, Dinsdale D, Cohen JJ, Squier MK, Malkinson AM.

Methods Mol Med. 2003;74:283-97. No abstract available.


Celecoxib reduces pulmonary inflammation but not lung tumorigenesis in mice.

Kisley LR, Barrett BS, Dwyer-Nield LD, Bauer AK, Thompson DC, Malkinson AM.

Carcinogenesis. 2002 Oct;23(10):1653-60.


Specific chromosomal aberrations in mouse lung adenocarcinoma cell lines detected by spectral karyotyping: a comparison with human lung adenocarcinoma.

Sargent LM, Senft JR, Lowry DT, Jefferson AM, Tyson FL, Malkinson AM, Coleman AE, Reynolds SH.

Cancer Res. 2002 Feb 15;62(4):1152-7.


Manipulation of pulmonary prostacyclin synthase expression prevents murine lung cancer.

Keith RL, Miller YE, Hoshikawa Y, Moore MD, Gesell TL, Gao B, Malkinson AM, Golpon HA, Nemenoff RA, Geraci MW.

Cancer Res. 2002 Feb 1;62(3):734-40.


The lung tumor promoter, butylated hydroxytoluene (BHT), causes chronic inflammation in promotion-sensitive BALB/cByJ mice but not in promotion-resistant CXB4 mice.

Bauer AK, Dwyer-Nield LD, Hankin JA, Murphy RC, Malkinson AM.

Toxicology. 2001 Dec 1;169(1):1-15. Erratum in: Toxicology 2002 Jul 1;176(1-2):159-61.


Cyclin D1 as a proliferative marker regulating retinoblastoma phosphorylation in mouse lung epithelial cells.

Mamay CL, Schauer IE, Rice PL, McDoniels-Silvers A, Dwyer-Nield LD, You M, Sclafani RA, Malkinson AM.

Cancer Lett. 2001 Jul 26;168(2):165-72. Erratum in: Cancer Lett 2002 Jun 28;180(2):223.


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