Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 120


Neutrophils enhance early Trypanosoma brucei infection onset.

Caljon G, Mabille D, Stijlemans B, De Trez C, Mazzone M, Tacchini-Cottier F, Malissen M, A Van Ginderachter J, Magez S, De Baetselier P, Van Den Abbeele J.

Sci Rep. 2018 Jul 25;8(1):11203. doi: 10.1038/s41598-018-29527-y.


LatY136F knock-in mouse model for human IgG4-related disease.

Yamada K, Zuka M, Ito K, Mizuguchi K, Kakuchi Y, Onoe T, Suzuki Y, Yamagishi M, Izui S, Malissen M, Malissen B, Kawano M.

PLoS One. 2018 Jun 14;13(6):e0198417. doi: 10.1371/journal.pone.0198417. eCollection 2018.


Tumor-associated neutrophils suppress pro-tumoral IL-17+ γδ T cells through induction of oxidative stress.

Mensurado S, Rei M, Lança T, Ioannou M, Gonçalves-Sousa N, Kubo H, Malissen M, Papayannopoulos V, Serre K, Silva-Santos B.

PLoS Biol. 2018 May 11;16(5):e2004990. doi: 10.1371/journal.pbio.2004990. eCollection 2018 May.


Diversity of innate immune cell subsets across spatial and temporal scales in an EAE mouse model.

Caravagna C, Jaouën A, Desplat-Jégo S, Fenrich KK, Bergot E, Luche H, Grenot P, Rougon G, Malissen M, Debarbieux F.

Sci Rep. 2018 Mar 23;8(1):5146. doi: 10.1038/s41598-018-22872-y.


In Utero Administration of Drugs Targeting Microglia Improves the Neurodevelopmental Outcome Following Cytomegalovirus Infection of the Rat Fetal Brain.

Cloarec R, Bauer S, Teissier N, Schaller F, Luche H, Courtens S, Salmi M, Pauly V, Bois E, Pallesi-Pocachard E, Buhler E, Michel FJ, Gressens P, Malissen M, Stamminger T, Streblow DN, Bruneau N, Szepetowski P.

Front Cell Neurosci. 2018 Mar 6;12:55. doi: 10.3389/fncel.2018.00055. eCollection 2018.


Unveiling skin macrophage dynamics explains both tattoo persistence and strenuous removal.

Baranska A, Shawket A, Jouve M, Baratin M, Malosse C, Voluzan O, Vu Manh TP, Fiore F, Bajénoff M, Benaroch P, Dalod M, Malissen M, Henri S, Malissen B.

J Exp Med. 2018 Apr 2;215(4):1115-1133. doi: 10.1084/jem.20171608. Epub 2018 Mar 6.


Atp6ap2 ablation in adult mice impairs viability through multiple organ deficiencies.

Wendling O, Champy MF, Jaubert S, Pavlovic G, Dubos A, Lindner L, Jacobs H, Mark M, Combe R, Da Cruz IG, Luche H, Mudgett JS, Rosahl T, Sorg T, Malissen M, Reilly PT, Hérault Y.

Sci Rep. 2017 Aug 29;7(1):9618. doi: 10.1038/s41598-017-08845-7.


Innate Immune Basis for Rift Valley Fever Susceptibility in Mouse Models.

Lathan R, Simon-Chazottes D, Jouvion G, Godon O, Malissen M, Flamand M, Bruhns P, Panthier JJ.

Sci Rep. 2017 Aug 2;7(1):7096. doi: 10.1038/s41598-017-07543-8.


Natural Killer Defective Maturation Is Associated with Adverse Clinical Outcome in Patients with Acute Myeloid Leukemia.

Chretien AS, Fauriat C, Orlanducci F, Galseran C, Rey J, Bouvier Borg G, Gautherot E, Granjeaud S, Hamel-Broza JF, Demerle C, Ifrah N, Lacombe C, Cornillet-Lefebvre P, Delaunay J, Toubert A, Gregori E, Luche H, Malissen M, Arnoulet C, Nunes JA, Vey N, Olive D.

Front Immunol. 2017 May 29;8:573. doi: 10.3389/fimmu.2017.00573. eCollection 2017.


Erratum: Reply to "Neutrophils are not required for resolution of acute gouty arthritis in mice".

Reinwald C, Schauer C, Csepregi JZ, Kienhöfer D, Weidner D, Malissen M, Mocsai A, Schett G, Herrmann M, Hoffmann M.

Nat Med. 2017 Apr 7;23(4):526. doi: 10.1038/nm0417-526b. No abstract available.


Precise Temporal Profiling of Signaling Complexes in Primary Cells Using SWATH Mass Spectrometry.

Caron E, Roncagalli R, Hase T, Wolski WE, Choi M, Menoita MG, Durand S, García-Blesa A, Fierro-Monti I, Sajic T, Heusel M, Weiss T, Malissen M, Schlapbach R, Collins BC, Ghosh S, Kitano H, Aebersold R, Malissen B, Gstaiger M.

Cell Rep. 2017 Mar 28;18(13):3219-3226. doi: 10.1016/j.celrep.2017.03.019.


Reply to "Neutrophils are not required for resolution of acute gouty arthritis in mice".

Reinwald C, Schauer C, Csepregi JZ, Kienhöfer D, Weidner D, Malissen M, Mocsai A, Schett G, Herrmann M, Hoffmann M.

Nat Med. 2016 Dec 6;22(12):1384-1386. doi: 10.1038/nm.4217. No abstract available. Erratum in: Nat Med. 2017 Apr 7;23 (4):526.


Dual T cell- and B cell-intrinsic deficiency in humans with biallelic RLTPR mutations.

Wang Y, Ma CS, Ling Y, Bousfiha A, Camcioglu Y, Jacquot S, Payne K, Crestani E, Roncagalli R, Belkadi A, Kerner G, Lorenzo L, Deswarte C, Chrabieh M, Patin E, Vincent QB, Müller-Fleckenstein I, Fleckenstein B, Ailal F, Quintana-Murci L, Fraitag S, Alyanakian MA, Leruez-Ville M, Picard C, Puel A, Bustamante J, Boisson-Dupuis S, Malissen M, Malissen B, Abel L, Hovnanian A, Notarangelo LD, Jouanguy E, Tangye SG, Béziat V, Casanova JL.

J Exp Med. 2016 Oct 17;213(11):2413-2435. Epub 2016 Sep 19.


The scaffolding function of the RLTPR protein explains its essential role for CD28 co-stimulation in mouse and human T cells.

Roncagalli R, Cucchetti M, Jarmuzynski N, Grégoire C, Bergot E, Audebert S, Baudelet E, Menoita MG, Joachim A, Durand S, Suchanek M, Fiore F, Zhang L, Liang Y, Camoin L, Malissen M, Malissen B.

J Exp Med. 2016 Oct 17;213(11):2437-2457. Epub 2016 Sep 19.


The transcriptional repressor Gfi1 prevents lupus autoimmunity by restraining TLR7 signaling.

Desnues B, Macedo AB, Ordoñez-Rueda D, Roussel-Queval A, Malissen B, Bruhns P, Malissen M, Alexopoulou L.

Eur J Immunol. 2016 Dec;46(12):2801-2811. doi: 10.1002/eji.201646573. Epub 2016 Oct 4.


Co-recruitment analysis of the CBL and CBLB signalosomes in primary T cells identifies CD5 as a key regulator of TCR-induced ubiquitylation.

Voisinne G, García-Blesa A, Chaoui K, Fiore F, Bergot E, Girard L, Malissen M, Burlet-Schiltz O, Gonzalez de Peredo A, Malissen B, Roncagalli R.

Mol Syst Biol. 2016 Jul 29;12(7):876. doi: 10.15252/msb.20166837.


Cytomegalovirus Infection of the Rat Developing Brain In Utero Prominently Targets Immune Cells and Promotes Early Microglial Activation.

Cloarec R, Bauer S, Luche H, Buhler E, Pallesi-Pocachard E, Salmi M, Courtens S, Massacrier A, Grenot P, Teissier N, Watrin F, Schaller F, Adle-Biassette H, Gressens P, Malissen M, Stamminger T, Streblow DN, Bruneau N, Szepetowski P.

PLoS One. 2016 Jul 29;11(7):e0160176. doi: 10.1371/journal.pone.0160176. eCollection 2016.


CD6 modulates thymocyte selection and peripheral T cell homeostasis.

Orta-Mascaró M, Consuegra-Fernández M, Carreras E, Roncagalli R, Carreras-Sureda A, Alvarez P, Girard L, Simões I, Martínez-Florensa M, Aranda F, Merino R, Martínez VG, Vicente R, Merino J, Sarukhan A, Malissen M, Malissen B, Lozano F.

J Exp Med. 2016 Jul 25;213(8):1387-97. doi: 10.1084/jem.20151785. Epub 2016 Jul 4.


Phenotypic dynamics of microglial and monocyte-derived cells in glioblastoma-bearing mice.

Ricard C, Tchoghandjian A, Luche H, Grenot P, Figarella-Branger D, Rougon G, Malissen M, Debarbieux F.

Sci Rep. 2016 May 19;6:26381. doi: 10.1038/srep26381.


Revisiting the Timing of Action of the PAG Adaptor Using Quantitative Proteomics Analysis of Primary T Cells.

Reginald K, Chaoui K, Roncagalli R, Beau M, Goncalves Menoita M, Monsarrat B, Burlet-Schiltz O, Malissen M, Gonzalez de Peredo A, Malissen B.

J Immunol. 2015 Dec 1;195(11):5472-81. doi: 10.4049/jimmunol.1501300. Epub 2015 Oct 28.


Rapid Sequestration of Leishmania mexicana by Neutrophils Contributes to the Development of Chronic Lesion.

Hurrell BP, Schuster S, Grün E, Coutaz M, Williams RA, Held W, Malissen B, Malissen M, Yousefi S, Simon HU, Müller AJ, Tacchini-Cottier F.

PLoS Pathog. 2015 May 28;11(5):e1004929. doi: 10.1371/journal.ppat.1004929. eCollection 2015 May.


In the absence of its cytosolic domain, the CD28 molecule still contributes to T cell activation.

Morin SO, Giroux V, Favre C, Bechah Y, Auphan-Anezin N, Roncagalli R, Mège JL, Olive D, Malissen M, Nunès JA.

Cell Mol Life Sci. 2015 Jul;72(14):2739-48. doi: 10.1007/s00018-015-1873-7. Epub 2015 Mar 1.


Evaluating the efficiency of isotope transmission for improved panel design and a comparison of the detection sensitivities of mass cytometer instruments.

Tricot S, Meyrand M, Sammicheli C, Elhmouzi-Younes J, Corneau A, Bertholet S, Malissen M, Le Grand R, Nuti S, Luche H, Cosma A.

Cytometry A. 2015 Apr;87(4):357-68. doi: 10.1002/cyto.a.22648. Epub 2015 Feb 20.


Sox17 regulates liver lipid metabolism and adaptation to fasting.

Rommelaere S, Millet V, Vu Manh TP, Gensollen T, Andreoletti P, Cherkaoui-Malki M, Bourges C, Escalière B, Du X, Xia Y, Imbert J, Beutler B, Kanai Y, Malissen B, Malissen M, Tailleux A, Staels B, Galland F, Naquet P.

PLoS One. 2014 Aug 20;9(8):e104925. doi: 10.1371/journal.pone.0104925. eCollection 2014.


Integrative biology of T cell activation.

Malissen B, Grégoire C, Malissen M, Roncagalli R.

Nat Immunol. 2014 Sep;15(9):790-7. doi: 10.1038/ni.2959. Review.


Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hub.

Roncagalli R, Hauri S, Fiore F, Liang Y, Chen Z, Sansoni A, Kanduri K, Joly R, Malzac A, Lähdesmäki H, Lahesmaa R, Yamasaki S, Saito T, Malissen M, Aebersold R, Gstaiger M, Malissen B.

Nat Immunol. 2014 Apr;15(4):384-392. doi: 10.1038/ni.2843. Epub 2014 Mar 2.


The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells.

Liang Y, Cucchetti M, Roncagalli R, Yokosuka T, Malzac A, Bertosio E, Imbert J, Nijman IJ, Suchanek M, Saito T, Wülfing C, Malissen B, Malissen M.

Nat Immunol. 2013 Aug;14(8):858-66. doi: 10.1038/ni.2634. Epub 2013 Jun 23.


Neutrophils exert a suppressive effect on Th1 responses to intracellular pathogen Brucella abortus.

Barquero-Calvo E, Martirosyan A, Ordoñez-Rueda D, Arce-Gorvel V, Alfaro-Alarcón A, Lepidi H, Malissen B, Malissen M, Gorvel JP, Moreno E.

PLoS Pathog. 2013 Feb;9(2):e1003167. doi: 10.1371/journal.ppat.1003167. Epub 2013 Feb 14.


A hypomorphic mutation in the Gfi1 transcriptional repressor results in a novel form of neutropenia.

Ordoñez-Rueda D, Jönsson F, Mancardi DA, Zhao W, Malzac A, Liang Y, Bertosio E, Grenot P, Blanquet V, Sabrautzki S, de Angelis MH, Méresse S, Duprez E, Bruhns P, Malissen B, Malissen M.

Eur J Immunol. 2012 Sep;42(9):2395-408. doi: 10.1002/eji.201242589.


Dominant Role of CD80-CD86 Over CD40 and ICOSL in the Massive Polyclonal B Cell Activation Mediated by LAT(Y136F) CD4(+) T Cells.

Chevrier S, Genton C, Malissen B, Malissen M, Acha-Orbea H.

Front Immunol. 2012 Feb 24;3:27. doi: 10.3389/fimmu.2012.00027. eCollection 2012.


Neutrophil depletion impairs natural killer cell maturation, function, and homeostasis.

Jaeger BN, Donadieu J, Cognet C, Bernat C, Ordoñez-Rueda D, Barlogis V, Mahlaoui N, Fenis A, Narni-Mancinelli E, Beaupain B, Bellanné-Chantelot C, Bajénoff M, Malissen B, Malissen M, Vivier E, Ugolini S.

J Exp Med. 2012 Mar 12;209(3):565-80. doi: 10.1084/jem.20111908. Epub 2012 Mar 5.


Tuning of natural killer cell reactivity by NKp46 and Helios calibrates T cell responses.

Narni-Mancinelli E, Jaeger BN, Bernat C, Fenis A, Kung S, De Gassart A, Mahmood S, Gut M, Heath SC, Estellé J, Bertosio E, Vely F, Gastinel LN, Beutler B, Malissen B, Malissen M, Gut IG, Vivier E, Ugolini S.

Science. 2012 Jan 20;335(6066):344-8. doi: 10.1126/science.1215621.


DelK32-lamin A/C has abnormal location and induces incomplete tissue maturation and severe metabolic defects leading to premature death.

Bertrand AT, Renou L, Papadopoulos A, Beuvin M, Lacène E, Massart C, Ottolenghi C, Decostre V, Maron S, Schlossarek S, Cattin ME, Carrier L, Malissen M, Arimura T, Bonne G.

Hum Mol Genet. 2012 Mar 1;21(5):1037-48. doi: 10.1093/hmg/ddr534. Epub 2011 Nov 16.


LAT signaling pathology: an "autoimmune" condition without T cell self-reactivity.

Roncagalli R, Mingueneau M, Grégoire C, Malissen M, Malissen B.

Trends Immunol. 2010 Jul;31(7):253-9. doi: 10.1016/ Epub 2010 Jun 9. Review.


Lymphoproliferative disorders involving T helper effector cells with defective LAT signalosomes.

Roncagalli R, Mingueneau M, Grégoire C, Langlet C, Malissen B, Malissen M.

Semin Immunopathol. 2010 Jun;32(2):117-25. doi: 10.1007/s00281-009-0195-y. Epub 2010 Jan 28. Review.


A hypomorphic allele of ZAP-70 reveals a distinct thymic threshold for autoimmune disease versus autoimmune reactivity.

Hsu LY, Tan YX, Xiao Z, Malissen M, Weiss A.

J Exp Med. 2009 Oct 26;206(11):2527-41. doi: 10.1084/jem.20082902. Epub 2009 Oct 19.


Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor.

Mingueneau M, Roncagalli R, Grégoire C, Kissenpfennig A, Miazek A, Archambaud C, Wang Y, Perrin P, Bertosio E, Sansoni A, Richelme S, Locksley RM, Aguado E, Malissen M, Malissen B.

Immunity. 2009 Aug 21;31(2):197-208. doi: 10.1016/j.immuni.2009.05.013. Epub 2009 Aug 13.


Thymus-specific serine protease regulates positive selection of a subset of CD4+ thymocytes.

Gommeaux J, Grégoire C, Nguessan P, Richelme M, Malissen M, Guerder S, Malissen B, Carrier A.

Eur J Immunol. 2009 Apr;39(4):956-64. doi: 10.1002/eji.200839175.


STAT6 deletion converts the Th2 inflammatory pathology afflicting Lat(Y136F) mice into a lymphoproliferative disorder involving Th1 and CD8 effector T cells.

Archambaud C, Sansoni A, Mingueneau M, Devilard E, Delsol G, Malissen B, Malissen M.

J Immunol. 2009 Mar 1;182(5):2680-9. doi: 10.4049/jimmunol.0803257.


CD93 is required for maintenance of antibody secretion and persistence of plasma cells in the bone marrow niche.

Chevrier S, Genton C, Kallies A, Karnowski A, Otten LA, Malissen B, Malissen M, Botto M, Corcoran LM, Nutt SL, Acha-Orbea H.

Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3895-900. doi: 10.1073/pnas.0809736106. Epub 2009 Feb 19.


The proline-rich sequence of CD3epsilon controls T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytes.

Mingueneau M, Sansoni A, Grégoire C, Roncagalli R, Aguado E, Weiss A, Malissen M, Malissen B.

Nat Immunol. 2008 May;9(5):522-32. doi: 10.1038/ni.1608. Epub 2008 Apr 13.


Non-T cell activation linker promotes mast cell survival by dampening the recruitment of SHIP1 by linker for activation of T cells.

Roget K, Malissen M, Malbec O, Malissen B, Daëron M.

J Immunol. 2008 Mar 15;180(6):3689-98.


Mannosidase I inhibition rescues the human alpha-sarcoglycan R77C recurrent mutation.

Bartoli M, Gicquel E, Barrault L, Soheili T, Malissen M, Malissen B, Vincent-Lacaze N, Perez N, Udd B, Danos O, Richard I.

Hum Mol Genet. 2008 May 1;17(9):1214-21. doi: 10.1093/hmg/ddn029. Epub 2008 Feb 5.


Th2 lymphoproliferative disorder of LatY136F mutant mice unfolds independently of TCR-MHC engagement and is insensitive to the action of Foxp3+ regulatory T cells.

Wang Y, Kissenpfennig A, Mingueneau M, Richelme S, Perrin P, Chevrier S, Genton C, Lucas B, DiSanto JP, Acha-Orbea H, Malissen B, Malissen M.

J Immunol. 2008 Feb 1;180(3):1565-75.


Deletion of the LIME adaptor protein minimally affects T and B cell development and function.

Grégoire C, Simova S, Wang Y, Sansoni A, Richelme S, Schmidt-Giese A, Simeoni L, Angelisova P, Reinhold D, Schraven B, Horejsi V, Malissen B, Malissen M.

Eur J Immunol. 2007 Nov;37(11):3259-69.


Roles of the C-terminal tyrosine residues of LAT in GPVI-induced platelet activation: insights into the mechanism of PLC gamma 2 activation.

Ragab A, Séverin S, Gratacap MP, Aguado E, Malissen M, Jandrot-Perrus M, Malissen B, Ragab-Thomas J, Payrastre B.

Blood. 2007 Oct 1;110(7):2466-74. Epub 2007 Jun 19.


Impaired accumulation of antigen-specific CD8 lymphocytes in chemokine CCL25-deficient intestinal epithelium and lamina propria.

Wurbel MA, Malissen M, Guy-Grand D, Malissen B, Campbell JJ.

J Immunol. 2007 Jun 15;178(12):7598-606.


Th2 lymphoproliferative disorders resulting from defective LAT signalosomes.

Malissen B, Wang Y, Mingueneau M, Malissen M.

Novartis Found Symp. 2007;281:93-100; discussion 100-2, 208-9. Review.


The Th2 lymphoproliferation developing in LatY136F mutant mice triggers polyclonal B cell activation and systemic autoimmunity.

Genton C, Wang Y, Izui S, Malissen B, Delsol G, Fournié GJ, Malissen M, Acha-Orbea H.

J Immunol. 2006 Aug 15;177(4):2285-93.


Visualization of the earliest steps of gammadelta T cell development in the adult thymus.

Prinz I, Sansoni A, Kissenpfennig A, Ardouin L, Malissen M, Malissen B.

Nat Immunol. 2006 Sep;7(9):995-1003. Epub 2006 Jul 30.


Supplemental Content

Loading ...
Support Center