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Items: 26

1.

Hitting the sweet spot.

Malins LR.

Nat Chem. 2018 Jun;10(6):578-580. doi: 10.1038/s41557-018-0071-2. No abstract available.

PMID:
29784990
2.

Peptide modification and cyclization via transition-metal catalysis.

Malins LR.

Curr Opin Chem Biol. 2018 Apr 12;46:25-32. doi: 10.1016/j.cbpa.2018.03.019. [Epub ahead of print] Review.

PMID:
29656180
3.

CITU: A Peptide and Decarboxylative Coupling Reagent.

deGruyter JN, Malins LR, Wimmer L, Clay KJ, Lopez-Ogalla J, Qin T, Cornella J, Liu Z, Che G, Bao D, Stevens JM, Qiao JX, Allen MP, Poss MA, Baran PS.

Org Lett. 2017 Nov 17;19(22):6196-6199. doi: 10.1021/acs.orglett.7b03121. Epub 2017 Nov 8.

PMID:
29115835
4.

Residue-Specific Peptide Modification: A Chemist's Guide.

deGruyter JN, Malins LR, Baran PS.

Biochemistry. 2017 Aug 1;56(30):3863-3873. doi: 10.1021/acs.biochem.7b00536. Epub 2017 Jul 17. Review.

5.

Decarboxylative Alkynylation.

Smith JM, Qin T, Merchant RR, Edwards JT, Malins LR, Liu Z, Che G, Shen Z, Shaw SA, Eastgate MD, Baran PS.

Angew Chem Int Ed Engl. 2017 Sep 18;56(39):11906-11910. doi: 10.1002/anie.201705107. Epub 2017 Aug 1.

PMID:
28636185
6.

Decarboxylative alkenylation.

Edwards JT, Merchant RR, McClymont KS, Knouse KW, Qin T, Malins LR, Vokits B, Shaw SA, Bao DH, Wei FL, Zhou T, Eastgate MD, Baran PS.

Nature. 2017 May 11;545(7653):213-218. doi: 10.1038/nature22307. Epub 2017 Apr 19.

7.

Peptide Macrocyclization Inspired by Non-Ribosomal Imine Natural Products.

Malins LR, deGruyter JN, Robbins KJ, Scola PM, Eastgate MD, Ghadiri MR, Baran PS.

J Am Chem Soc. 2017 Mar 31. doi: 10.1021/jacs.7b01624. [Epub ahead of print]

8.

Strain-Release Heteroatom Functionalization: Development, Scope, and Stereospecificity.

Lopchuk JM, Fjelbye K, Kawamata Y, Malins LR, Pan CM, Gianatassio R, Wang J, Prieto L, Bradow J, Brandt TA, Collins MR, Elleraas J, Ewanicki J, Farrell W, Fadeyi OO, Gallego GM, Mousseau JJ, Oliver R, Sach NW, Smith JK, Spangler JE, Zhu H, Zhu J, Baran PS.

J Am Chem Soc. 2017 Mar 1;139(8):3209-3226. doi: 10.1021/jacs.6b13229. Epub 2017 Feb 20.

9.

Nickel-Catalyzed Barton Decarboxylation and Giese Reactions: A Practical Take on Classic Transforms.

Qin T, Malins LR, Edwards JT, Merchant RR, Novak AJ, Zhong JZ, Mills RB, Yan M, Yuan C, Eastgate MD, Baran PS.

Angew Chem Int Ed Engl. 2017 Jan 2;56(1):260-265. doi: 10.1002/anie.201609662. Epub 2016 Dec 16.

10.

One-Pot Ligation-Oxidative Deselenization at Selenocysteine and Selenocystine.

Mitchell NJ, Kulkarni SS, Malins LR, Wang S, Payne RJ.

Chemistry. 2017 Jan 18;23(4):946-952. doi: 10.1002/chem.201604709. Epub 2016 Dec 14.

PMID:
27859731
11.

Single addition of an allylamine monomer enables access to end-functionalized RAFT polymers for native chemical ligation.

Isahak N, Gody G, Malins LR, Mitchell NJ, Payne RJ, Perrier S.

Chem Commun (Camb). 2016 Oct 27;52(88):12952-12955.

PMID:
27722654
12.

A general alkyl-alkyl cross-coupling enabled by redox-active esters and alkylzinc reagents.

Qin T, Cornella J, Li C, Malins LR, Edwards JT, Kawamura S, Maxwell BD, Eastgate MD, Baran PS.

Science. 2016 May 13;352(6287):801-5. doi: 10.1126/science.aaf6123. Epub 2016 Apr 21.

13.

Organic chemistry. Strain-release amination.

Gianatassio R, Lopchuk JM, Wang J, Pan CM, Malins LR, Prieto L, Brandt TA, Collins MR, Gallego GM, Sach NW, Spangler JE, Zhu H, Zhu J, Baran PS.

Science. 2016 Jan 15;351(6270):241-6. doi: 10.1126/science.aad6252.

14.

Rapid additive-free selenocystine-selenoester peptide ligation.

Mitchell NJ, Malins LR, Liu X, Thompson RE, Chan B, Radom L, Payne RJ.

J Am Chem Soc. 2015 Nov 11;137(44):14011-4. doi: 10.1021/jacs.5b07237. Epub 2015 Nov 3.

PMID:
26487084
15.

Thiazolidine-Protected β-Thiol Asparagine: Applications in One-Pot Ligation-Desulfurization Chemistry.

Sayers J, Thompson RE, Perry KJ, Malins LR, Payne RJ.

Org Lett. 2015 Oct 2;17(19):4902-5. doi: 10.1021/acs.orglett.5b02468.

PMID:
26398220
16.

Oxidative Deselenization of Selenocysteine: Applications for Programmed Ligation at Serine.

Malins LR, Mitchell NJ, McGowan S, Payne RJ.

Angew Chem Int Ed Engl. 2015 Oct 19;54(43):12716-21. doi: 10.1002/anie.201504639. Epub 2015 Sep 1.

PMID:
26384718
17.

Synthesis of β-Thiol Phenylalanine for Applications in One-Pot Ligation-Desulfurization Chemistry.

Malins LR, Giltrap AM, Dowman LJ, Payne RJ.

Org Lett. 2015 May 1;17(9):2070-3. doi: 10.1021/acs.orglett.5b00597. Epub 2015 Apr 10.

PMID:
25860301
18.

Modern extensions of native chemical ligation for chemical protein synthesis.

Malins LR, Payne RJ.

Top Curr Chem. 2015;362:27-87. doi: 10.1007/128_2014_584.

PMID:
25518971
19.

Recent extensions to native chemical ligation for the chemical synthesis of peptides and proteins.

Malins LR, Payne RJ.

Curr Opin Chem Biol. 2014 Oct;22:70-8. doi: 10.1016/j.cbpa.2014.09.021. Epub 2014 Oct 3. Review.

PMID:
25285753
20.

Site-selective solid-phase synthesis of a CCR5 sulfopeptide library to interrogate HIV binding and entry.

Liu X, Malins LR, Roche M, Sterjovski J, Duncan R, Garcia ML, Barnes NC, Anderson DA, Stone MJ, Gorry PR, Payne RJ.

ACS Chem Biol. 2014 Sep 19;9(9):2074-81. doi: 10.1021/cb500337r. Epub 2014 Jul 24.

21.

One-pot peptide ligation-desulfurization at glutamate.

Cergol KM, Thompson RE, Malins LR, Turner P, Payne RJ.

Org Lett. 2014 Jan 3;16(1):290-3. doi: 10.1021/ol403288n. Epub 2013 Dec 2.

PMID:
24294973
22.

Peptide ligation chemistry at selenol amino acids.

Malins LR, Mitchell NJ, Payne RJ.

J Pept Sci. 2014 Feb;20(2):64-77. doi: 10.1002/psc.2581. Epub 2013 Nov 28. Review.

PMID:
24285588
23.

Peptide ligation-desulfurization chemistry at arginine.

Malins LR, Cergol KM, Payne RJ.

Chembiochem. 2013 Mar 18;14(5):559-63. doi: 10.1002/cbic.201300049. Epub 2013 Feb 20.

PMID:
23426906
24.

Synthesis and utility of β-selenol-phenylalanine for native chemical ligation-deselenization chemistry.

Malins LR, Payne RJ.

Org Lett. 2012 Jun 15;14(12):3142-5. doi: 10.1021/ol3012265. Epub 2012 May 29.

PMID:
22642500
25.

Self-adjuvanting multicomponent cancer vaccine candidates combining per-glycosylated MUC1 glycopeptides and the Toll-like receptor 2 agonist Pam3CysSer.

Wilkinson BL, Day S, Malins LR, Apostolopoulos V, Payne RJ.

Angew Chem Int Ed Engl. 2011 Feb 11;50(7):1635-9. doi: 10.1002/anie.201006115. Epub 2011 Jan 7. No abstract available.

PMID:
21308921
26.

Synthesis of MUC1-lipopeptide chimeras.

Wilkinson BL, Malins LR, Chun CK, Payne RJ.

Chem Commun (Camb). 2010 Sep 14;46(34):6249-51. doi: 10.1039/c0cc01360a. Epub 2010 Jul 28.

PMID:
20664875

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