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Items: 10

1.

Optimization of Canalicular ABC Transporter Function in HuH-7 Cells by Modification of Culture Conditions.

Kang HE, Malinen MM, Saran C, Honkakoski P, Brouwer KLR.

Drug Metab Dispos. 2019 Oct;47(10):1222-1230. doi: 10.1124/dmd.119.087676. Epub 2019 Aug 1.

PMID:
31371422
2.

Protein expression and function of organic anion transporters in short-term and long-term cultures of Huh7 human hepatoma cells.

Malinen MM, Ito K, Kang HE, Honkakoski P, Brouwer KLR.

Eur J Pharm Sci. 2019 Mar 15;130:186-195. doi: 10.1016/j.ejps.2019.01.022. Epub 2019 Jan 24.

PMID:
30685239
3.

Novel in Vitro Method Reveals Drugs That Inhibit Organic Solute Transporter Alpha/Beta (OSTα/β).

Malinen MM, Kauttonen A, Beaudoin JJ, Sjöstedt N, Honkakoski P, Brouwer KLR.

Mol Pharm. 2019 Jan 7;16(1):238-246. doi: 10.1021/acs.molpharmaceut.8b00966. Epub 2018 Dec 14.

PMID:
30481467
4.

Organic solute transporter OSTα/β is overexpressed in nonalcoholic steatohepatitis and modulated by drugs associated with liver injury.

Malinen MM, Ali I, Bezençon J, Beaudoin JJ, Brouwer KLR.

Am J Physiol Gastrointest Liver Physiol. 2018 May 1;314(5):G597-G609. doi: 10.1152/ajpgi.00310.2017. Epub 2018 Feb 8.

5.

Regulation of Human Pluripotent Stem Cell-Derived Hepatic Cell Phenotype by Three-Dimensional Hydrogel Models.

Toivonen S, Malinen MM, Küblbeck J, Petsalo A, Urtti A, Honkakoski P, Otonkoski T.

Tissue Eng Part A. 2016 Jul;22(13-14):971-84. doi: 10.1089/ten.TEA.2016.0127. Epub 2016 Jul 7.

PMID:
27329070
6.

Hepatic differentiation of human pluripotent stem cells on human liver progenitor HepaRG-derived acellular matrix.

Kanninen LK, Porola P, Niklander J, Malinen MM, Corlu A, Guguen-Guillouzo C, Urtti A, Yliperttula ML, Lou YR.

Exp Cell Res. 2016 Feb 15;341(2):207-17. doi: 10.1016/j.yexcr.2016.02.006. Epub 2016 Feb 8.

PMID:
26854693
7.

Differentiation of liver progenitor cell line to functional organotypic cultures in 3D nanofibrillar cellulose and hyaluronan-gelatin hydrogels.

Malinen MM, Kanninen LK, Corlu A, Isoniemi HM, Lou YR, Yliperttula ML, Urtti AO.

Biomaterials. 2014 Jun;35(19):5110-21. doi: 10.1016/j.biomaterials.2014.03.020. Epub 2014 Apr 1.

8.

Nanofibrillar cellulose hydrogel promotes three-dimensional liver cell culture.

Bhattacharya M, Malinen MM, Lauren P, Lou YR, Kuisma SW, Kanninen L, Lille M, Corlu A, GuGuen-Guillouzo C, Ikkala O, Laukkanen A, Urtti A, Yliperttula M.

J Control Release. 2012 Dec 28;164(3):291-8. doi: 10.1016/j.jconrel.2012.06.039. Epub 2012 Jul 7.

9.

Peptide nanofiber hydrogel induces formation of bile canaliculi structures in three-dimensional hepatic cell culture.

Malinen MM, Palokangas H, Yliperttula M, Urtti A.

Tissue Eng Part A. 2012 Dec;18(23-24):2418-25. doi: 10.1089/ten.TEA.2012.0046. Epub 2012 Jul 30.

PMID:
22712588
10.

Modulation of cancer cell survival pathways using multivalent liposomal therapeutic antibody constructs.

Chiu GN, Edwards LA, Kapanen AI, Malinen MM, Dragowska WH, Warburton C, Chikh GG, Fang KY, Tan S, Sy J, Tucker C, Waterhouse DN, Klasa R, Bally MB.

Mol Cancer Ther. 2007 Mar;6(3):844-55. Epub 2007 Mar 5.

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