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Items: 8


Comparison of Analytical Methods for Antibody-Drug Conjugates Produced by Chemical Site-Specific Conjugation: First-Generation AJICAP.

Matsuda Y, Robles V, Malinao MC, Song J, Mendelsohn BA.

Anal Chem. 2019 Oct 15;91(20):12724-12732. doi: 10.1021/acs.analchem.9b02192. Epub 2019 Sep 3.


Metabolism of an Oxime-Linked Antibody Drug Conjugate, AGS62P1, and Characterization of Its Identified Metabolite.

Snyder JT, Malinao MC, Dugal-Tessier J, Atkinson JE, Anand BS, Okada A, Mendelsohn BA.

Mol Pharm. 2018 Jun 4;15(6):2384-2390. doi: 10.1021/acs.molpharmaceut.8b00225. Epub 2018 May 14.


A Potential Mechanism for ADC-Induced Neutropenia: Role of Neutrophils in Their Own Demise.

Zhao H, Gulesserian S, Malinao MC, Ganesan SK, Song J, Chang MS, Williams MM, Zeng Z, Mattie M, Mendelsohn BA, Stover DR, DoƱate F.

Mol Cancer Ther. 2017 Sep;16(9):1866-1876. doi: 10.1158/1535-7163.MCT-17-0133. Epub 2017 May 18.


A functional approach reveals a genetic and physical interaction between ribonucleotide reductase and CHK1 in mammalian cells.

Taricani L, Shanahan F, Malinao MC, Beaumont M, Parry D.

PLoS One. 2014 Nov 6;9(11):e111714. doi: 10.1371/journal.pone.0111714. eCollection 2014.


The identification of novel 5'-amino gemcitabine analogs as potent RRM1 inhibitors.

Labroli MA, Dwyer MP, Shen R, Popovici-Muller J, Pu Q, Wyss D, McCoy M, Barrett D, Davis N, Seghezzi W, Shanahan F, Taricani L, Beaumont M, Malinao MC, Parry D, Guzi TJ.

Bioorg Med Chem. 2014 Apr 1;22(7):2303-10. doi: 10.1016/j.bmc.2014.02.007. Epub 2014 Feb 15.


Biomarkers of Therapeutic Response in the IL-23 Pathway in Inflammatory Bowel Disease.

Cayatte C, Joyce-Shaikh B, Vega F, Boniface K, Grein J, Murphy E, Blumenschein WM, Chen S, Malinao MC, Basham B, Pierce RH, Bowman EP, McKenzie BS, Elson CO, Faubion WA, Malefyt Rde W, Kastelein RA, Cua D, McClanahan TK, Beaumont M.

Clin Transl Gastroenterol. 2012 Feb 16;3:e10. doi: 10.1038/ctg.2012.2.


Biomarkers of disease and treatment in murine and cynomolgus models of chronic asthma.

Louten J, Mattson JD, Malinao MC, Li Y, Emson C, Vega F, Wardle RL, Van Scott MR, Fick RB, McClanahan TK, de Waal Malefyt R, Beaumont M.

Biomark Insights. 2012;7:87-104. doi: 10.4137/BMI.S9776. Epub 2012 Jul 10.


Differential expression of monocyte/macrophage- selective markers in human idiopathic pulmonary fibrosis.

Desai B, Mattson J, Paintal H, Nathan M, Shen F, Beaumont M, Malinao MC, Li Y, Canfield J, Basham B, de Waal Malefyt R, McClanahan T, Krishna G, Fick R Jr.

Exp Lung Res. 2011 May;37(4):227-38. doi: 10.3109/01902148.2010.538132. Epub 2011 Feb 11.


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