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Computationally guided identification of Akt-3, a serine/threonine kinase inhibitors: Insights from homology modelling, structure-based screening, molecular dynamics and quantum mechanical calculations.

Srivastava S, Mehta P, Sharma O, Sharma M, Malik R.

J Biomol Struct Dyn. 2019 Oct 8:1-11. doi: 10.1080/07391102.2019.1675536. [Epub ahead of print]


Cryo-EM structure and dynamics of eukaryotic DNA polymerase δ holoenzyme.

Jain R, Rice WJ, Malik R, Johnson RE, Prakash L, Prakash S, Ubarretxena-Belandia I, Aggarwal AK.

Nat Struct Mol Biol. 2019 Oct;26(10):955-962. doi: 10.1038/s41594-019-0305-z. Epub 2019 Oct 3.


Hepatopulmonary Syndrome in a Thirteen Year Old Boy: A Case Report.

Shahid M, Tameez Ud Din A, Chaudhary FMD, Malik R, Tameez-Ud-Din A.

Cureus. 2019 Aug 1;11(8):e5295. doi: 10.7759/cureus.5295.


Identification of the environmental source of infection for a domestic ferret with cryptococcosis.

Schmertmann LJ, Wardman A, Setyo L, Kan A, Meyer W, Malik R, Krockenberger MB.

J Vet Diagn Invest. 2019 Sep 24:1040638719876968. doi: 10.1177/1040638719876968. [Epub ahead of print]


The mycobiome of Australian tree hollows in relation to the Cryptococcus gattii and C. neoformans species complexes.

Schmertmann LJ, Irinyi L, Malik R, Powell JR, Meyer W, Krockenberger MB.

Ecol Evol. 2019 Aug 7;9(17):9684-9700. doi: 10.1002/ece3.5498. eCollection 2019 Sep.


Sickle Cell Intrahepatic Cholestasis with Acute Liver Failure and Acute Kidney Injury: Favourable Outcome with Exchange Transfusion.

Maji P, Malik R, Lodha R, Bagga A.

Indian J Pediatr. 2019 Sep 13. doi: 10.1007/s12098-019-03071-7. [Epub ahead of print] No abstract available.


Expression of p-16, Ki-67 and p-53 markers in dysplastic and malignant lesions of the oral cavity and oropharynx.

Yadav P, Malik R, Balani S, Nigam RK, Jain P, Tandon P.

J Oral Maxillofac Pathol. 2019 May-Aug;23(2):224-230. doi: 10.4103/jomfp.JOMFP_299_18.


Male sexual dysfunction in obesity: The role of sex hormones and small fibre neuropathy.

Ho JH, Adam S, Azmi S, Ferdousi M, Liu Y, Kalteniece A, Dhage SS, Keevil BG, Syed AA, Ammori BJ, Ahern T, Donn R, Malik RA, Soran H.

PLoS One. 2019 Sep 11;14(9):e0221992. doi: 10.1371/journal.pone.0221992. eCollection 2019.


Myelopreservation with the CDK4/6 inhibitor trilaciclib in patients with small cell lung cancer receiving 1st-line chemotherapy: a Phase 1b/randomized Phase 2 trial.

Weiss JM, Csoszi T, Maglakelidze M, Hoyer RJ, Beck JT, Gomez MD, Lowczak A, Aljumaily R, Lima CMR, Boccia RV, Hanna W, Nikolinakos P, Chiu VK, Owonikoko TK, Schuster SR, Hussein MA, Richards DA, Sawrycki P, Bulat I, Hamm JT, Hart LL, Adler S, Antal JM, Lai AY, Sorrentino JA, Yang Z, Malik RK, Morris SR, Roberts PJ, Dragnev KH; G1T28-02 Study Group.

Ann Oncol. 2019 Aug 27. pii: mdz278. doi: 10.1093/annonc/mdz278. [Epub ahead of print]


Incidence of Intraocular Lens Exchange after Cataract Surgery.

Abdalla Elsayed MEA, Ahmad K, Al-Abdullah AA, Malik R, Khandekar R, Martinez-Osorio H, Mura M, Schatz P.

Sci Rep. 2019 Sep 9;9(1):12877. doi: 10.1038/s41598-019-49030-2.


The Atherosclerosis Risk Variant rs2107595 Mediates Allele-Specific Transcriptional Regulation of HDAC9 via E2F3 and Rb1.

Prestel M, Prell-Schicker C, Webb T, Malik R, Lindner B, Ziesch N, Rex-Haffner M, Röh S, Viturawong T, Lehm M, Mokry M, den Ruijter H, Haitjema S, Asare Y, Söllner F, Najafabadi MG, Aherrahrou R, Civelek M, Samani NJ, Mann M, Haffner C, Dichgans M.

Stroke. 2019 Oct;50(10):2651-2660. doi: 10.1161/STROKEAHA.119.026112. Epub 2019 Sep 10.


Successful use of secnidazole to manage a giardiosis outbreak in a shelter.

Cheung W, Russo C, Maher S, Malik R, Šlapeta J.

Vet Parasitol. 2019 Aug 14;274:108911. doi: 10.1016/j.vetpar.2019.08.005. [Epub ahead of print]


High-dose etoposide and cyclophosphamide in adults and children with primary refractory and multiply relapsed acute leukaemias: The Royal Marsden experience.

Carceller F, Hirsch SG, Khabra K, Petterson T, Malik R, Guerra-García P, Moreno L, Marshall LV, Taj M, Atra A, Ethell M, Potter M, Lancaster D.

Leuk Res. 2019 Aug 13;85:106217. doi: 10.1016/j.leukres.2019.106217. [Epub ahead of print]


Circulating Monocyte Chemoattractant Protein-1 and Risk of Stroke: Meta-Analysis of Population-Based Studies Involving 17 180 Individuals.

Georgakis MK, Malik R, Björkbacka H, Pana TA, Demissie S, Ayers C, Elhadad MA, Fornage M, Beiser AS, Benjamin EJ, Boekholdt MS, Engström G, Herder C, Hoogeveen RC, Koenig W, Melander O, Orho-Melander M, Schiopu A, Söderholm M, Wareham N, Ballantyne CM, Peters A, Seshadri S, Myint PK, Nilsson J, de Lemos JA, Dichgans M.

Circ Res. 2019 Sep 27;125(8):773-782. doi: 10.1161/CIRCRESAHA.119.315380. Epub 2019 Sep 3.


Commentary: Retrospective and prospective perspectives on zoonotic brucellosis.

Kneipp C, Malik R, Mor SM, Wiethoelter AK.

Front Microbiol. 2019 Aug 14;10:1859. doi: 10.3389/fmicb.2019.01859. eCollection 2019. No abstract available.


Improvements in skilled walking associated with kinematic adaptations in people with spinal cord injury.

Malik RN, Eginyan G, Lynn AK, Lam T.

J Neuroeng Rehabil. 2019 Aug 28;16(1):107. doi: 10.1186/s12984-019-0575-z.


Genome-wide association study of cerebral small vessel disease reveals established and novel loci.

Chung J, Marini S, Pera J, Norrving B, Jimenez-Conde J, Roquer J, Fernandez-Cadenas I, Tirschwell DL, Selim M, Brown DL, Silliman SL, Worrall BB, Meschia JF, Demel S, Greenberg SM, Slowik A, Lindgren A, Schmidt R, Traylor M, Sargurupremraj M, Tiedt S, Malik R, Debette S, Dichgans M, Langefeld CD, Woo D, Rosand J, Anderson CD.

Brain. 2019 Oct 1;142(10):3176-3189. doi: 10.1093/brain/awz233.


Using Gamification to Understand Accreditation in Postgraduate Medical Education.

Akdemir N, Malik RF, Walters T, Taber S, Hamstra SJ, Philibert I, Scheele F.

J Grad Med Educ. 2019 Aug;11(4 Suppl):207-210. doi: 10.4300/JGME-D-19-00051. No abstract available.


Posterior Compartment Prolapse Occurrence After Anterior Vaginal Wall Suspension.

Malik RD, Christie AL, Zimmern PE.

Urology. 2019 Aug 16. pii: S0090-4295(19)30718-6. doi: 10.1016/j.urology.2019.08.010. [Epub ahead of print]


Identifying Barriers to the Treatmentof Chronic Hepatitis C Infection.

Al-Khazraji A, Patel I, Saleh M, Ashraf A, Lieber J, Malik R.

Dig Dis. 2019 Aug 16:1-7. doi: 10.1159/000501821. [Epub ahead of print]


Ocular coherence tomography for the diagnosis of Descemet's detachment after deep sclerectomy and resolution after intracameral air injection.

AlZaid A, AlDarrab A, Malik R, Owaidhah O.

Am J Ophthalmol Case Rep. 2019 Jul 8;15:100509. doi: 10.1016/j.ajoc.2019.100509. eCollection 2019 Sep.


Small Fibre Neuropathy in Parkinson's Disease: Comparison of Skin Biopsies from the More Affected and Less Affected Sides.

Jeziorska M, Atkinson A, Kass-Iliyya L, Kobylecki C, Gosal D, Marshall A, Malik RA, Silverdale M.

J Parkinsons Dis. 2019 Jul 29. doi: 10.3233/JPD-191697. [Epub ahead of print]


Current policies and practicing surgeon perspectives on parental leave.

Gaines T, Harkhani N, Chen H, Malik RD.

Am J Surg. 2019 Oct;218(4):772-779. doi: 10.1016/j.amjsurg.2019.07.019. Epub 2019 Jul 19.


Reduction of skin innervation is associated with a severe fibromyalgia phenotype.

Evdokimov D, Frank J, Klitsch A, Unterecker S, Warrings B, Serra J, Papagianni A, Saffer N, Meyer Zu Altenschildesche C, Kampik D, Malik RA, Sommer C, Üçeyler N.

Ann Neurol. 2019 Oct;86(4):504-516. doi: 10.1002/ana.25565. Epub 2019 Aug 21.


Gender Disparities in Urology: How Can We Close the Gap?

Malik RD.

Urology. 2019 Jul 30. pii: S0090-4295(19)30686-7. doi: 10.1016/j.urology.2019.05.057. [Epub ahead of print] No abstract available.


Heart V5 predicts cardiac events in unresectable lung cancer patients undergoing chemoradiation.

Ni L, Koshy M, Connell P, Pitroda S, Golden DW, Al-Hallaq H, Hubert G, Kauffman G, McCall A, Malik R.

J Thorac Dis. 2019 Jun;11(6):2229-2239. doi: 10.21037/jtd.2019.06.29.


Pediatric chylous ascites treatment with combined ultrasound and fluoroscopy-guided intranodal lymphangiography.

Vora ZA, Kandasamy D, Naranje P, Malik R.

Indian J Radiol Imaging. 2019 Apr-Jun;29(2):226-228. doi: 10.4103/ijri.IJRI_424_18.


Effect of temperature and pH on the probiotication of Punica granatum juice using Lactobacillus species.

Mustafa SM, Chua LS, El-Enshasy HA, Abd Majid FA, Hanapi SZ, Abdul Malik R.

J Food Biochem. 2019 Apr;43(4):e12805. doi: 10.1111/jfbc.12805. Epub 2019 Feb 11.


The impact of caregiver health literacy on healthcare outcomes for low income minority children with asthma.

Belice PJ, Mosnaim G, Galant S, Kim Y, Shin HW, Pires-Barracosa N, Hall JP, Malik R, Becker E.

J Asthma. 2019 Aug 8:1-7. doi: 10.1080/02770903.2019.1648507. [Epub ahead of print]


Ba5Zn4Gd8O21:Tb3+-structural characterization and the judd-ofelt parameterization from emission spectra.

Dalal J, Dalal M, Devi S, Chahar S, Hooda A, Khatkar A, Malik RK, Taxak VB, Khatkar SP.

Methods Appl Fluoresc. 2019 Jul 19. doi: 10.1088/2050-6120/ab33b6. [Epub ahead of print]


Domain Comparison Between 6 Validated Questionnaires Administered to Women With Urinary Incontinence.

Malik RD, Hess DS, Christie A, Carmel ME, Zimmern PE.

Urology. 2019 Oct;132:75-80. doi: 10.1016/j.urology.2019.07.008. Epub 2019 Jul 13.


Subtype Specificity of Genetic Loci Associated With Stroke in 16 664 Cases and 32 792 Controls.

Traylor M, Anderson CD, Rutten-Jacobs LCA, Falcone GJ, Comeau ME, Ay H, Sudlow CLM, Xu H, Mitchell BD, Cole JW, Rexrode K, Jimenez-Conde J, Schmidt R, Grewal RP, Sacco R, Ribases M, Rundek T, Rosand J, Dichgans M, Lee JM, Langefeld CD, Kittner SJ, Markus HS, Woo D, Malik R; NINDS Stroke Genetics Network (SiGN) and International Stroke Genetics Consortium (ISGC).

Circ Genom Precis Med. 2019 Jul;12(7):e002338. doi: 10.1161/CIRCGEN.118.002338. Epub 2019 Jul 15.


Taking the climate risk out of transplanted and direct seeded rice: Insights from dynamic simulation in Eastern India.

Balwinder-Singh, McDonald AJ, Kumar V, Poonia SP, Srivastava AK, Malik RK.

Field Crops Res. 2019 Jun 1;239:92-103. doi: 10.1016/j.fcr.2019.05.014.


Spectrum of Endoscopic Findings in Patients of Upper Gastrointestinal Bleeding at a Tertiary Care Hospital.

Malghani WS, Malik R, Chaudhary FMD, Tameez Ud Din A, Shahid M, Ahmad S, Tameez Ud Din A, Chaudhary SMD.

Cureus. 2019 Apr 29;11(4):e4562. doi: 10.7759/cureus.4562.


Myeloid-Specific Deletion of the AMPKα2 Subunit Alters Monocyte Protein Expression and Atherogenesis.

Fisslthaler B, Zippel N, Abdel Malik R, Delgado Lagos F, Zukunft S, Thoele J, Siuda D, Soehnlein O, Wittig I, Heidler J, Weigert A, Fleming I.

Int J Mol Sci. 2019 Jun 19;20(12). pii: E3005. doi: 10.3390/ijms20123005.


Use of Genetic Variants Related to Antihypertensive Drugs to Inform on Efficacy and Side Effects.

Gill D, Georgakis MK, Koskeridis F, Jiang L, Feng Q, Wei WQ, Theodoratou E, Elliott P, Denny JC, Malik R, Evangelou E, Dehghan A, Dichgans M, Tzoulaki I.

Circulation. 2019 Jul 23;140(4):270-279. doi: 10.1161/CIRCULATIONAHA.118.038814. Epub 2019 Jun 25.


Comparing immunochromatography with latex antigen agglutination testing for the diagnosis of cryptococcosis in cats, dogs and koalas.

Krockenberger MB, Marschner C, Martin P, Reppas G, Halliday C, Schmertmann LJ, Harvey AM, Malik R.

Med Mycol. 2019 Mar 9. pii: myz010. doi: 10.1093/mmy/myz010. [Epub ahead of print]


Current antibiotic use in the treatment of enteric fever in children.

Dahiya S, Malik R, Sharma P, Sashi A, Lodha R, Kabra SK, Sood S, Das BK, Walia K, Ohri VC, Kapil A.

Indian J Med Res. 2019 Feb;149(2):263-269. doi: 10.4103/ijmr.IJMR_199_18.


In Vivo Implications of Potential Probiotic Lactobacillus reuteri LR6 on the Gut and Immunological Parameters as an Adjuvant Against Protein Energy Malnutrition.

Garg S, Singh TP, Malik RK.

Probiotics Antimicrob Proteins. 2019 Jun 19. doi: 10.1007/s12602-019-09563-4. [Epub ahead of print]


Early corneal nerve fibre damage and increased Langerhans cell density in children with type 1 diabetes mellitus.

Ferdousi M, Romanchuk K, Mah JK, Virtanen H, Millar C, Malik RA, Pacaud D.

Sci Rep. 2019 Jun 19;9(1):8758. doi: 10.1038/s41598-019-45116-z.


Early nerve fibre regeneration in individuals with type 1 diabetes after simultaneous pancreas and kidney transplantation.

Azmi S, Jeziorska M, Ferdousi M, Petropoulos IN, Ponirakis G, Marshall A, Alam U, Asghar O, Atkinson A, Jones W, Boulton AJM, Brines M, Augustine T, Malik RA.

Diabetologia. 2019 Aug;62(8):1478-1487. doi: 10.1007/s00125-019-4897-y. Epub 2019 Jun 7.


Jet-Setting Koalas Spread Cryptococcus gattii VGII in Australia.

Schmertmann LJ, Danesi P, Monroy-Nieto J, Bowers J, Engelthaler DM, Malik R, Meyer W, Krockenberger MB.

mSphere. 2019 Jun 5;4(3). pii: e00216-19. doi: 10.1128/mSphere.00216-19.


Editorial Comment.

Malik RD.

J Urol. 2019 Sep;202(3):572. doi: 10.1097/01.JU.0000558552.60504.d8. Epub 2019 Aug 8. No abstract available.


Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.

Malik R, Chauhan G, Traylor M, Sargurupremraj M, Okada Y, Mishra A, Rutten-Jacobs L, Giese AK, van der Laan SW, Gretarsdottir S, Anderson CD, Chong M, Adams HHH, Ago T, Almgren P, Amouyel P, Ay H, Bartz TM, Benavente OR, Bevan S, Boncoraglio GB, Brown RD Jr, Butterworth AS, Carrera C, Carty CL, Chasman DI, Chen WM, Cole JW, Correa A, Cotlarciuc I, Cruchaga C, Danesh J, de Bakker PIW, DeStefano AL, den Hoed M, Duan Q, Engelter ST, Falcone GJ, Gottesman RF, Grewal RP, Gudnason V, Gustafsson S, Haessler J, Harris TB, Hassan A, Havulinna AS, Heckbert SR, Holliday EG, Howard G, Hsu FC, Hyacinth HI, Ikram MA, Ingelsson E, Irvin MR, Jian X, Jiménez-Conde J, Johnson JA, Jukema JW, Kanai M, Keene KL, Kissela BM, Kleindorfer DO, Kooperberg C, Kubo M, Lange LA, Langefeld CD, Langenberg C, Launer LJ, Lee JM, Lemmens R, Leys D, Lewis CM, Lin WY, Lindgren AG, Lorentzen E, Magnusson PK, Maguire J, Manichaikul A, McArdle PF, Meschia JF, Mitchell BD, Mosley TH, Nalls MA, Ninomiya T, O'Donnell MJ, Psaty BM, Pulit SL, Rannikmäe K, Reiner AP, Rexrode KM, Rice K, Rich SS, Ridker PM, Rost NS, Rothwell PM, Rotter JI, Rundek T, Sacco RL, Sakaue S, Sale MM, Salomaa V, Sapkota BR, Schmidt R, Schmidt CO, Schminke U, Sharma P, Slowik A, Sudlow CLM, Tanislav C, Tatlisumak T, Taylor KD, Thijs VNS, Thorleifsson G, Thorsteinsdottir U, Tiedt S, Trompet S, Tzourio C, van Duijn CM, Walters M, Wareham NJ, Wassertheil-Smoller S, Wilson JG, Wiggins KL, Yang Q, Yusuf S; AFGen Consortium; Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium; International Genomics of Blood Pressure (iGEN-BP) Consortium; INVENT Consortium; STARNET, Bis JC, Pastinen T, Ruusalepp A, Schadt EE, Koplev S, Björkegren JLM, Codoni V, Civelek M, Smith NL, Trégouët DA, Christophersen IE, Roselli C, Lubitz SA, Ellinor PT, Tai ES, Kooner JS, Kato N, He J, van der Harst P, Elliott P, Chambers JC, Takeuchi F, Johnson AD; BioBank Japan Cooperative Hospital Group; COMPASS Consortium; EPIC-CVD Consortium; EPIC-InterAct Consortium; International Stroke Genetics Consortium (ISGC); METASTROKE Consortium; Neurology Working Group of the CHARGE Consortium; NINDS Stroke Genetics Network (SiGN); UK Young Lacunar DNA Study; MEGASTROKE Consortium, Sanghera DK, Melander O, Jern C, Strbian D, Fernandez-Cadenas I, Longstreth WT Jr, Rolfs A, Hata J, Woo D, Rosand J, Pare G, Hopewell JC, Saleheen D, Stefansson K, Worrall BB, Kittner SJ, Seshadri S, Fornage M, Markus HS, Howson JMM, Kamatani Y, Debette S, Dichgans M.

Nat Genet. 2019 Jul;51(7):1192-1193. doi: 10.1038/s41588-019-0449-0.


The Diagnosis of Feline Leukaemia Virus (FeLV) Infection in Owned and Group-Housed Rescue Cats in Australia.

Westman M, Norris J, Malik R, Hofmann-Lehmann R, Harvey A, McLuckie A, Perkins M, Schofield D, Marcus A, McDonald M, Ward M, Hall E, Sheehy P, Hosie M.

Viruses. 2019 May 31;11(6). pii: E503. doi: 10.3390/v11060503.


Correction: Corneal nerve and endothelial cell damage in patients with transient ischemic attack and minor ischemic stroke.

Gad H, Khan A, Akhtar N, Kamran S, El-Sotouhy A, Dargham SR, Petropoulos IN, Ponirakis G, Shuaib A, Streletz LJ, Malik RA.

PLoS One. 2019 May 28;14(5):e0217672. doi: 10.1371/journal.pone.0217672. eCollection 2019.


Knowledge Preserving OSELM Model for Wi-Fi-Based Indoor Localization.

Al-Khaleefa AS, Ahmad MR, Isa AAM, Esa MRM, Aljeroudi Y, Jubair MA, Malik RF.

Sensors (Basel). 2019 May 25;19(10). pii: E2397. doi: 10.3390/s19102397.


Understanding the consequences of education inequality on cardiovascular disease: mendelian randomisation study.

Carter AR, Gill D, Davies NM, Taylor AE, Tillmann T, Vaucher J, Wootton RE, Munafò MR, Hemani G, Malik R, Seshadri S, Woo D, Burgess S, Davey Smith G, Holmes MV, Tzoulaki I, Howe LD, Dehghan A.

BMJ. 2019 May 22;365:l1855. doi: 10.1136/bmj.l1855.


Decreased CSF Levels of ß-Amyloid in Patients With Cortical Superficial Siderosis.

Catak C, Zedde M, Malik R, Janowitz D, Soric V, Seegerer A, Krebs A, Düring M, Opherk C, Linn J, Wollenweber FA.

Front Neurol. 2019 Apr 26;10:439. doi: 10.3389/fneur.2019.00439. eCollection 2019.

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