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Items: 1 to 50 of 147

1.

Functional metagenomics-guided discovery of potent Cas9 inhibitors in the human microbiome.

Forsberg KJ, Bhatt IV, Schmidtke DT, Javanmardi K, Dillard KE, Stoddard BL, Finkelstein IJ, Kaiser BK, Malik HS.

Elife. 2019 Sep 10;8. pii: e46540. doi: 10.7554/eLife.46540.

2.

Density-dependent resistance protects Legionella pneumophila from its own antimicrobial metabolite, HGA.

Levin TC, Goldspiel BP, Malik HS.

Elife. 2019 May 28;8. pii: e46086. doi: 10.7554/eLife.46086.

3.

Clinico-Haematologic association and prognostic relevance of NPM1 and FLT3-ITD mutations in acute Myeloid Leukaemia.

Mahmood R, Altaf C, Malik HS, Khan SA.

Pak J Med Sci. 2019 Jan-Feb;35(1):23-28. doi: 10.12669/pjms.35.1.285.

4.

The PLOS Biology XV Collection: 15 Years of Exceptional Science Highlighted across 12 Months.

Richardson LA, Schmid SL, Bhandoola A, Harly C, Hedenström A, Laub MT, Mace GM, Sengupta P, Stock AM, Read AF, Malik HS, Estelle M, Lowell S, Kimmelman J.

PLoS Biol. 2019 Feb 27;17(2):e3000180. doi: 10.1371/journal.pbio.3000180. eCollection 2019 Feb. No abstract available.

5.

Clinicohematological parameters and outcomes in a cohort of chronic lymphocytic leukemia patients with Deletion 17p from Pakistan.

Mahmood R, Khan SA, Altaf C, Malik HS, Khadim MT.

Blood Res. 2018 Dec;53(4):276-280. doi: 10.5045/br.2018.53.4.276. Epub 2018 Dec 17.

6.

Thiamine Responsive Megaloblastic Anaemia, Diabetes Mellitus and Sensorineural Hearing Loss in a Child.

Khurshid A, Fatima S, Altaf C, Malik HS, Sajjad Z, Khadim MT.

J Coll Physicians Surg Pak. 2018 Sep;28(9):S169-S171. doi: 10.29271/jcpsp.2018.09.S169.

PMID:
30173687
7.

Kindr Motors Drive in Meiosis.

Schroeder CM, Malik HS.

Cell. 2018 May 3;173(4):813-815. doi: 10.1016/j.cell.2018.04.021.

8.

Berardinelli-Seip Congenital Generalised Lipodystrophy.

Cheema HA, Malik HS, Waheed N, Mushtaq I, Fayyaz Z, Anjum MN.

J Coll Physicians Surg Pak. 2018 May;28(5):406-408. doi: 10.29271/jcpsp.2018.05.406.

PMID:
29690976
9.

Microbial Genomics: The Expanding Universe of Bacterial Defense Systems.

Forsberg KJ, Malik HS.

Curr Biol. 2018 Apr 23;28(8):R361-R364. doi: 10.1016/j.cub.2018.02.053.

10.

Evolutionary origins and diversification of testis-specific short histone H2A variants in mammals.

Molaro A, Young JM, Malik HS.

Genome Res. 2018 Apr;28(4):460-473. doi: 10.1101/gr.229799.117. Epub 2018 Mar 16.

11.

Electrocardiographic Manifestations In Paediatric Wilson Disease.

Batool Hamdani SS, Cheema HA, Saeed A, Malik HS, Sehar T.

J Ayub Med Coll Abbottabad. 2018 Jan-Mar;30(1):22-25.

12.

The cellular mechanisms and consequences of centromere drive.

Kursel LE, Malik HS.

Curr Opin Cell Biol. 2018 Jun;52:58-65. doi: 10.1016/j.ceb.2018.01.011. Epub 2018 Feb 16. Review.

13.

Culture shock.

Molaro A, Malik HS.

Elife. 2017 Dec 18;6. pii: e33312. doi: 10.7554/eLife.33312.

14.

Delta-Beta Thalassaemia in a Pathan Family.

Ahmad SQ, Zafar SI, Malik HS, Ahmed S.

J Coll Physicians Surg Pak. 2017 Nov;27(11):722-724. doi: 2752.

PMID:
29132487
15.

Genetics: Master Regulator or Master of Disguise?

Ailion M, Malik HS.

Curr Biol. 2017 Sep 11;27(17):R844-R847. doi: 10.1016/j.cub.2017.07.030.

16.

Waddington Redux: De Novo Mutations Underlie the Genetic Assimilation of Stress-Induced Phenocopies in Drosophila melanogaster.

Kasinathan B, Ahmad K, Malik HS.

Genetics. 2017 Sep;207(1):49-51. doi: 10.1534/genetics.117.205039. No abstract available.

17.

The gene drive bubble: New realities.

Bull JJ, Malik HS.

PLoS Genet. 2017 Jul 20;13(7):e1006850. doi: 10.1371/journal.pgen.1006850. eCollection 2017 Jul. No abstract available.

18.

Spontaneous Perforation Of Bile Duct, Clinical Presentation, Laboratory Work Up, Treatment And Outcome.

Malik HS, Cheema HA, Fayyaz Z, Hashmi MA, Parkash A, Waheed N, Mushtaq I, Anjum N.

J Ayub Med Coll Abbottabad. 2016 Jul-Sep;28(3):518-522.

19.

Causes Of Chronic Non-Infectious Diarrhoea In Infants Less Than 6 Months Of Age: Rarely Recognized Entities.

Mushtaq I, Cheema HA, Malik HS, Waheed N, Hashmi MA, Malik HS.

J Ayub Med Coll Abbottabad. 2017 Jan-Mar;29(1):78-82.

20.

Clinical Spectrum Of Solitary Rectal Ulcer In Children Presenting With Per-Rectal Bleed.

Anjum MN, Cheema HA, Malik HS, Hashmi MA.

J Ayub Med Coll Abbottabad. 2017 Jan-Mar;29(1):74-77.

21.

wtf genes are prolific dual poison-antidote meiotic drivers.

Nuckolls NL, Bravo Núñez MA, Eickbush MT, Young JM, Lange JJ, Yu JS, Smith GR, Jaspersen SL, Malik HS, Zanders SE.

Elife. 2017 Jun 20;6. pii: e26033. doi: 10.7554/eLife.26033.

22.

Myelodysplastic Syndrome in Pakistan: Clinicohematological Characteristics, Cytogenetic Profile, and Risk Stratification.

Mahmood R, Altaf C, Ahmed P, Khan SA, Malik HS.

Turk J Haematol. 2018 May 25;35(2):109-115. doi: 10.4274/tjh.2017.0130. Epub 2017 Jun 7.

23.

Rapidly Evolving Toll-3/4 Genes Encode Male-Specific Toll-Like Receptors in Drosophila.

Levin TC, Malik HS.

Mol Biol Evol. 2017 Sep 1;34(9):2307-2323. doi: 10.1093/molbev/msx168.

24.

Corrigendum: Evolution of a transcriptional regulator from a transmembrane nucleoporin.

Franks TM, Benner C, Narvaiza I, Marchetto MCN, Young JM, Malik HS, Gage FH, Hetzer MW.

Genes Dev. 2017 Apr 15;31(8):845. doi: 10.1101/gad.300699.117. No abstract available.

25.

Recurrent Gene Duplication Leads to Diverse Repertoires of Centromeric Histones in Drosophila Species.

Kursel LE, Malik HS.

Mol Biol Evol. 2017 Jun 1;34(6):1445-1462. doi: 10.1093/molbev/msx091.

26.

Mucopolysaccharidoses - Clinical Spectrum and Frequency of Different Types.

Cheema HA, Malik HS, Hashmi MA, Fayyaz Z, Mushtaq I, Shahzadi N.

J Coll Physicians Surg Pak. 2017 Feb;27(2):80-83.

PMID:
28292383
27.

The piggyBac transposon-derived genes TPB1 and TPB6 mediate essential transposon-like excision during the developmental rearrangement of key genes in Tetrahymena thermophila.

Cheng CY, Young JM, Lin CG, Chao JL, Malik HS, Yao MC.

Genes Dev. 2016 Dec 15;30(24):2724-2736. doi: 10.1101/gad.290460.116.

28.

Genetic conflicts: the usual suspects and beyond.

McLaughlin RN Jr, Malik HS.

J Exp Biol. 2017 Jan 1;220(Pt 1):6-17. doi: 10.1242/jeb.148148. Review.

29.

Did a Single Amino Acid Change Make Ebola Virus More Virulent?

Bedford T, Malik HS.

Cell. 2016 Nov 3;167(4):892-894. doi: 10.1016/j.cell.2016.10.032.

30.

A Diversified Portfolio.

Goodin MM, Hatfull GF, Malik HS.

Annu Rev Virol. 2016 Sep 29;3(1):vi-viii. doi: 10.1146/annurev-vi-3-100316-100011. No abstract available.

PMID:
29092666
31.
32.

A mitochondrial DNA hypomorph of cytochrome oxidase specifically impairs male fertility in Drosophila melanogaster.

Patel MR, Miriyala GK, Littleton AJ, Yang H, Trinh K, Young JM, Kennedy SR, Yamashita YM, Pallanck LJ, Malik HS.

Elife. 2016 Aug 2;5. pii: e16923. doi: 10.7554/eLife.16923.

33.

Spectrum of Inherited Metabolic Disorders in Pakistani Children Presenting at a Tertiary Care Centre.

Cheema HA, Malik HS, Parkash A, Fayyaz Z.

J Coll Physicians Surg Pak. 2016 Jun;26(6):498-502. doi: 2350.

PMID:
27353988
34.

Centromeres.

Kursel LE, Malik HS.

Curr Biol. 2016 Jun 20;26(12):R487-R490. doi: 10.1016/j.cub.2016.05.031.

35.

Evolution-guided functional analyses reveal diverse antiviral specificities encoded by IFIT1 genes in mammals.

Daugherty MD, Schaller AM, Geballe AP, Malik HS.

Elife. 2016 May 31;5. pii: e14228. doi: 10.7554/eLife.14228.

36.

Evolution of a transcriptional regulator from a transmembrane nucleoporin.

Franks TM, Benner C, Narvaiza I, Marchetto MC, Young JM, Malik HS, Gage FH, Hetzer MW.

Genes Dev. 2016 May 15;30(10):1155-71. doi: 10.1101/gad.280941.116. Epub 2016 May 19. Erratum in: Genes Dev. 2017 Apr 15;31(8):845.

37.

Conservation and Innovation of APOBEC3A Restriction Functions during Primate Evolution.

McLaughlin RN Jr, Gable JT, Wittkopp CJ, Emerman M, Malik HS.

Mol Biol Evol. 2016 Aug;33(8):1889-901. doi: 10.1093/molbev/msw070. Epub 2016 Apr 6.

38.

Recurrent Gene Duplication Diversifies Genome Defense Repertoire in Drosophila.

Levine MT, Vander Wende HM, Hsieh E, Baker EP, Malik HS.

Mol Biol Evol. 2016 Jul;33(7):1641-53. doi: 10.1093/molbev/msw053. Epub 2016 Mar 14.

39.

Evolutionary Turnover of Kinetochore Proteins: A Ship of Theseus?

Drinnenberg IA, Henikoff S, Malik HS.

Trends Cell Biol. 2016 Jul;26(7):498-510. doi: 10.1016/j.tcb.2016.01.005. Epub 2016 Feb 11. Review.

40.

Hide and seek: how chromatin-based pathways silence retroelements in the mammalian germline.

Molaro A, Malik HS.

Curr Opin Genet Dev. 2016 Apr;37:51-58. doi: 10.1016/j.gde.2015.12.001. Epub 2016 Jan 26. Review.

41.

An essential cell cycle regulation gene causes hybrid inviability in Drosophila.

Phadnis N, Baker EP, Cooper JC, Frizzell KA, Hsieh E, de la Cruz AF, Shendure J, Kitzman JO, Malik HS.

Science. 2015 Dec 18;350(6267):1552-5. doi: 10.1126/science.aac7504.

42.

Evolutionary Analyses Suggest a Function of MxB Immunity Proteins Beyond Lentivirus Restriction.

Mitchell PS, Young JM, Emerman M, Malik HS.

PLoS Pathog. 2015 Dec 10;11(12):e1005304. doi: 10.1371/journal.ppat.1005304. eCollection 2015 Dec.

43.

Chromosome segregation: human female meiosis breaks all the rules.

Zanders SE, Malik HS.

Curr Biol. 2015 Aug 3;25(15):R654-6. doi: 10.1016/j.cub.2015.06.054.

44.

BIOSAFETY. Safeguarding gene drive experiments in the laboratory.

Akbari OS, Bellen HJ, Bier E, Bullock SL, Burt A, Church GM, Cook KR, Duchek P, Edwards OR, Esvelt KM, Gantz VM, Golic KG, Gratz SJ, Harrison MM, Hayes KR, James AA, Kaufman TC, Knoblich J, Malik HS, Matthews KA, O'Connor-Giles KM, Parks AL, Perrimon N, Port F, Russell S, Ueda R, Wildonger J.

Science. 2015 Aug 28;349(6251):927-9. doi: 10.1126/science.aac7932. Epub 2015 Jul 30. No abstract available.

45.

LINE-1 Retroelements Get ZAPped!

McLaughlin RN Jr, Malik HS.

PLoS Genet. 2015 Jul 16;11(7):e1005364. doi: 10.1371/journal.pgen.1005364. eCollection 2015 Jul. No abstract available.

46.

Mitotic fidelity requires transgenerational action of a testis-restricted HP1.

Levine MT, Vander Wende HM, Malik HS.

Elife. 2015 Jul 7;4:e07378. doi: 10.7554/eLife.07378.

47.

R2d2 and Hyperdrive Mechanisms (in Mouse Meiosis).

Zanders SE, Malik HS.

PLoS Genet. 2015 Feb 13;11(2):e1004950. doi: 10.1371/journal.pgen.1004950. eCollection 2015 Feb. No abstract available.

48.

Frequency of Gγ-globin promoter -158 (C>T) XmnI polymorphism in patients with homozygous/compound heterozygous beta thalassaemia.

Ali N, Ayyub M, Khan SA, Ahmed S, Abbas K, Malik HS, Tashfeen S.

Hematol Oncol Stem Cell Ther. 2015 Mar;8(1):10-5. doi: 10.1016/j.hemonc.2014.12.004. Epub 2015 Jan 6.

49.

Speciation via autoimmunity: a dangerous mix.

Phadnis N, Malik HS.

Cell. 2014 Dec 4;159(6):1247-9. doi: 10.1016/j.cell.2014.11.028.

50.

Transferred interbacterial antagonism genes augment eukaryotic innate immune function.

Chou S, Daugherty MD, Peterson SB, Biboy J, Yang Y, Jutras BL, Fritz-Laylin LK, Ferrin MA, Harding BN, Jacobs-Wagner C, Yang XF, Vollmer W, Malik HS, Mougous JD.

Nature. 2015 Feb 5;518(7537):98-101. doi: 10.1038/nature13965. Epub 2014 Nov 24.

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