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Items: 1 to 50 of 529

1.

Alveolar Stretch Activation of Endothelial Piezo1 Protects Adherens Junctions and Lung Vascular Barrier.

Zhong M, Wu W, Kang H, Hong Z, Xiong S, Gao X, Rehman J, Komarova YA, Malik AB.

Am J Respir Cell Mol Biol. 2019 Aug 13. doi: 10.1165/rcmb.2019-0024OC. [Epub ahead of print]

PMID:
31409093
2.

STAT6 induces expression of Gas6 in macrophages to clear apoptotic neutrophils and resolve inflammation.

Nepal S, Tiruppathi C, Tsukasaki Y, Farahany J, Mittal M, Rehman J, Prockop DJ, Malik AB.

Proc Natl Acad Sci U S A. 2019 Aug 13;116(33):16513-16518. doi: 10.1073/pnas.1821601116. Epub 2019 Jul 30.

3.

Caspase-11 Mediates Pyroptosis of Tubular Epithelial Cells and Septic Acute Kidney Injury.

Ye Z, Zhang L, Li R, Dong W, Liu S, Li Z, Liang H, Wang L, Shi W, Malik AB, Cheng KT, Liang X.

Kidney Blood Press Res. 2019;44(4):465-478. doi: 10.1159/000499685. Epub 2019 Jun 21.

4.

Endothelial cell Piezo1 mediates pressure-induced lung vascular hyperpermeability via disruption of adherens junctions.

Friedrich EE, Hong Z, Xiong S, Zhong M, Di A, Rehman J, Komarova YA, Malik AB.

Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):12980-12985. doi: 10.1073/pnas.1902165116. Epub 2019 Jun 11.

5.

Time-Variant SRC Kinase Activation Determines Endothelial Permeability Response.

Klomp JE, Shaaya M, Matsche J, Rebiai R, Aaron JS, Collins KB, Huyot V, Gonzalez AM, Muller WA, Chew TL, Malik AB, Karginov AV.

Cell Chem Biol. 2019 Aug 15;26(8):1081-1094.e6. doi: 10.1016/j.chembiol.2019.04.007. Epub 2019 May 23.

PMID:
31130521
6.

Sox17 is required for endothelial regeneration following inflammation-induced vascular injury.

Liu M, Zhang L, Marsboom G, Jambusaria A, Xiong S, Toth PT, Benevolenskaya EV, Rehman J, Malik AB.

Nat Commun. 2019 May 9;10(1):2126. doi: 10.1038/s41467-019-10134-y.

7.

VE-PTP stabilizes VE-cadherin junctions and the endothelial barrier via a phosphatase-independent mechanism.

Juettner VV, Kruse K, Dan A, Vu VH, Khan Y, Le J, Leckband D, Komarova Y, Malik AB.

J Cell Biol. 2019 May 6;218(5):1725-1742. doi: 10.1083/jcb.201807210. Epub 2019 Apr 4.

8.

A Tie2-Notch1 signaling axis regulates regeneration of the endothelial bone marrow niche.

Shao L, Sottoriva K, Palasiewicz K, Zhang J, Hyun J, Soni SS, Paik NY, Gao X, Cuervo H, Malik AB, Rehman J, Lucas D, Pajcini KV.

Haematologica. 2019 Nov;104(11):2164-2177. doi: 10.3324/haematol.2018.208660. Epub 2019 Mar 28.

9.

Dlk1-Mediated Temporal Regulation of Notch Signaling Is Required for Differentiation of Alveolar Type II to Type I Cells during Repair.

Finn J, Sottoriva K, Pajcini KV, Kitajewski JK, Chen C, Zhang W, Malik AB, Liu Y.

Cell Rep. 2019 Mar 12;26(11):2942-2954.e5. doi: 10.1016/j.celrep.2019.02.046.

10.

N-cadherin signaling via Trio assembles adherens junctions to restrict endothelial permeability.

Kruse K, Lee QS, Sun Y, Klomp J, Yang X, Huang F, Sun MY, Zhao S, Hong Z, Vogel SM, Shin JW, Leckband DE, Tai LM, Malik AB, Komarova YA.

J Cell Biol. 2019 Jan 7;218(1):299-316. doi: 10.1083/jcb.201802076. Epub 2018 Nov 21.

11.

The GTPase Rab1 Is Required for NLRP3 Inflammasome Activation and Inflammatory Lung Injury.

Zhang Y, Wang L, Lv Y, Jiang C, Wu G, Dull RO, Minshall RD, Malik AB, Hu G.

J Immunol. 2019 Jan 1;202(1):194-206. doi: 10.4049/jimmunol.1800777. Epub 2018 Nov 19.

PMID:
30455398
12.

Piezo1 mediates angiogenesis through activation of MT1-MMP signaling.

Kang H, Hong Z, Zhong M, Klomp J, Bayless KJ, Mehta D, Karginov AV, Hu G, Malik AB.

Am J Physiol Cell Physiol. 2019 Jan 1;316(1):C92-C103. doi: 10.1152/ajpcell.00346.2018. Epub 2018 Nov 14.

PMID:
30427721
13.

Renal toxicity with liposomal doxorubicin in metastatic breast cancer.

Yemm KE, Alwan LM, Malik AB, Salazar LG.

J Oncol Pharm Pract. 2019 Oct;25(7):1738-1742. doi: 10.1177/1078155218798157. Epub 2018 Aug 31.

PMID:
30170515
14.

The TWIK2 Potassium Efflux Channel in Macrophages Mediates NLRP3 Inflammasome-Induced Inflammation.

Di A, Xiong S, Ye Z, Malireddi RKS, Kometani S, Zhong M, Mittal M, Hong Z, Kanneganti TD, Rehman J, Malik AB.

Immunity. 2018 Jul 17;49(1):56-65.e4. doi: 10.1016/j.immuni.2018.04.032. Epub 2018 Jun 26.

15.

A computational approach to identify cellular heterogeneity and tissue-specific gene regulatory networks.

Jambusaria A, Klomp J, Hong Z, Rafii S, Dai Y, Malik AB, Rehman J.

BMC Bioinformatics. 2018 Jun 7;19(1):217. doi: 10.1186/s12859-018-2190-6.

16.

YAP Controls Endothelial Activation and Vascular Inflammation Through TRAF6.

Lv Y, Kim K, Sheng Y, Cho J, Qian Z, Zhao YY, Hu G, Pan D, Malik AB, Hu G.

Circ Res. 2018 Jun 22;123(1):43-56. doi: 10.1161/CIRCRESAHA.118.313143. Epub 2018 May 23.

17.

Mechanosensing Piezo channels in tissue homeostasis including their role in lungs.

Zhong M, Komarova Y, Rehman J, Malik AB.

Pulm Circ. 2018 Apr-Jun;8(2):2045894018767393. doi: 10.1177/2045894018767393. Epub 2018 Mar 9.

18.

Response by Mittal et al to Letter Regarding Article, "Neutrophil Activation of Endothelial Cell-Expressed TRPM2 Mediates Transendothelial Neutrophil Migration and Vascular Injury".

Mittal M, Nepal S, Tsukasaki Y, Hecquet CM, Soni D, Tiruppathi C, Malik AB, Rehman J.

Circ Res. 2017 Dec 8;121(12):e87. doi: 10.1161/CIRCRESAHA.117.312146. No abstract available.

19.

Caspase-11-mediated endothelial pyroptosis underlies endotoxemia-induced lung injury.

Cheng KT, Xiong S, Ye Z, Hong Z, Di A, Tsang KM, Gao X, An S, Mittal M, Vogel SM, Miao EA, Rehman J, Malik AB.

J Clin Invest. 2017 Nov 1;127(11):4124-4135. doi: 10.1172/JCI94495. Epub 2017 Oct 9.

20.

Reactive and anticipatory looking in 6-month-old infants during a visual expectation paradigm.

Quan J, Bureau JF, Abdul Malik AB, Wong J, Rifkin-Graboi A.

Data Brief. 2017 Sep 4;14:713-719. doi: 10.1016/j.dib.2017.08.049. eCollection 2017 Oct.

21.

Neutrophil Activation of Endothelial Cell-Expressed TRPM2 Mediates Transendothelial Neutrophil Migration and Vascular Injury.

Mittal M, Nepal S, Tsukasaki Y, Hecquet CM, Soni D, Rehman J, Tiruppathi C, Malik AB.

Circ Res. 2017 Oct 13;121(9):1081-1091. doi: 10.1161/CIRCRESAHA.117.311747. Epub 2017 Aug 8.

22.

Embryonic Stem Cell Differentiation to Functional Arterial Endothelial Cells through Sequential Activation of ETV2 and NOTCH1 Signaling by HIF1α.

Tsang KM, Hyun JS, Cheng KT, Vargas M, Mehta D, Ushio-Fukai M, Zou L, Pajcini KV, Rehman J, Malik AB.

Stem Cell Reports. 2017 Sep 12;9(3):796-806. doi: 10.1016/j.stemcr.2017.07.001. Epub 2017 Aug 3.

23.

The influence of CHRNA4, COMT, and maternal sensitivity on orienting and executive attention in 6-month-old infants.

Quan J, Ong ML, Bureau JF, Sim LW, Sanmugam S, Abdul Malik AB, Wong E, Wong J, Chong YS, Saw SM, Kwek K, Qiu A, Holbrook JD, Rifkin-Graboi A; GUSTO Study Group.

Brain Cogn. 2017 Aug;116:17-28. doi: 10.1016/j.bandc.2017.05.002. Epub 2017 Jun 3.

PMID:
28582665
24.

Aberrant caveolin-1-mediated Smad signaling and proliferation identified by analysis of adenine 474 deletion mutation (c.474delA) in patient fibroblasts: a new perspective on the mechanism of pulmonary hypertension.

Marsboom G, Chen Z, Yuan Y, Zhang Y, Tiruppathi C, Loyd JE, Austin ED, Machado RF, Minshall RD, Rehman J, Malik AB.

Mol Biol Cell. 2017 May 1;28(9):1177-1185. doi: 10.1091/mbc.E16-11-0790.

25.

Pyk2 phosphorylation of VE-PTP downstream of STIM1-induced Ca2+ entry regulates disassembly of adherens junctions.

Soni D, Regmi SC, Wang DM, DebRoy A, Zhao YY, Vogel SM, Malik AB, Tiruppathi C.

Am J Physiol Lung Cell Mol Physiol. 2017 Jun 1;312(6):L1003-L1017. doi: 10.1152/ajplung.00008.2017. Epub 2017 Apr 6.

26.

SOX17 Regulates Conversion of Human Fibroblasts Into Endothelial Cells and Erythroblasts by Dedifferentiation Into CD34+ Progenitor Cells.

Zhang L, Jambusaria A, Hong Z, Marsboom G, Toth PT, Herbert BS, Malik AB, Rehman J.

Circulation. 2017 Jun 20;135(25):2505-2523. doi: 10.1161/CIRCULATIONAHA.116.025722. Epub 2017 Apr 5.

27.

Aberrant Caveolin-1-Mediated Smad Signaling and Proliferation Identified by Analysis of Adenine 474 Deletion Mutation (c.474delA) in Patient Fibroblasts: A New Perspective in the Mechanism of Pulmonary Hypertension.

Marsboom G, Chen Z, Yuan Y, Zhang Y, Tiruppathi C, Loyd JE, Austin ED, Machado RF, Minshall RD, Rehman J, Malik AB.

Mol Biol Cell. 2017 Mar 15. pii: mbc.E16-06-0380. doi: 10.1091/mbc.E16-06-0380. [Epub ahead of print]

PMID:
28298490
28.

Response by Komarova et al to Letter Regarding Article, "Protein Interactions at Endothelial Junctions and Signaling Mechanisms Regulating Endothelial Permeability".

Komarova Y, Kruse KJ, Mehta D, Malik AB.

Circ Res. 2017 Mar 3;120(5):e28. doi: 10.1161/CIRCRESAHA.117.310647. No abstract available.

29.

Method for Dual Viral Vector Mediated CRISPR-Cas9 Gene Disruption in Primary Human Endothelial Cells.

Gong H, Liu M, Klomp J, Merrill BJ, Rehman J, Malik AB.

Sci Rep. 2017 Feb 15;7:42127. doi: 10.1038/srep42127.

30.

Role of the phagosomal redox-sensitive TRP channel TRPM2 in regulating bactericidal activity of macrophages.

Di A, Kiya T, Gong H, Gao X, Malik AB.

J Cell Sci. 2017 Feb 15;130(4):735-744. doi: 10.1242/jcs.196014. Epub 2017 Jan 12.

31.

Protein Interactions at Endothelial Junctions and Signaling Mechanisms Regulating Endothelial Permeability.

Komarova YA, Kruse K, Mehta D, Malik AB.

Circ Res. 2017 Jan 6;120(1):179-206. doi: 10.1161/CIRCRESAHA.116.306534. Review.

32.

Inactivation of Rab11a GTPase in Macrophages Facilitates Phagocytosis of Apoptotic Neutrophils.

Jiang C, Liu Z, Hu R, Bo L, Minshall RD, Malik AB, Hu G.

J Immunol. 2017 Feb 15;198(4):1660-1672. doi: 10.4049/jimmunol.1601495. Epub 2017 Jan 4.

33.

Mimicking transient activation of protein kinases in living cells.

Klomp JE, Huyot V, Ray AM, Collins KB, Malik AB, Karginov AV.

Proc Natl Acad Sci U S A. 2016 Dec 27;113(52):14976-14981. doi: 10.1073/pnas.1609675114. Epub 2016 Dec 12.

34.

TNFα-stimulated gene-6 (TSG6) activates macrophage phenotype transition to prevent inflammatory lung injury.

Mittal M, Tiruppathi C, Nepal S, Zhao YY, Grzych D, Soni D, Prockop DJ, Malik AB.

Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):E8151-E8158. Epub 2016 Nov 28.

35.

PAR1 Scaffolds TGFβRII to Downregulate TGF-β Signaling and Activate ESC Differentiation to Endothelial Cells.

Gong H, An S, Sassmann A, Liu M, Mastej V, Mittal M, Zhang W, Hong Z, Offermanns S, Rehman J, Malik AB.

Stem Cell Reports. 2016 Dec 13;7(6):1050-1058. doi: 10.1016/j.stemcr.2016.10.006. Epub 2016 Nov 17.

36.

Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy.

Cantelmo AR, Conradi LC, Brajic A, Goveia J, Kalucka J, Pircher A, Chaturvedi P, Hol J, Thienpont B, Teuwen LA, Schoors S, Boeckx B, Vriens J, Kuchnio A, Veys K, Cruys B, Finotto L, Treps L, Stav-Noraas TE, Bifari F, Stapor P, Decimo I, Kampen K, De Bock K, Haraldsen G, Schoonjans L, Rabelink T, Eelen G, Ghesquière B, Rehman J, Lambrechts D, Malik AB, Dewerchin M, Carmeliet P.

Cancer Cell. 2016 Dec 12;30(6):968-985. doi: 10.1016/j.ccell.2016.10.006. Epub 2016 Nov 17.

37.

Antiangiogenic Therapeutic Potential of Peptides Derived from the Molecular Motor KIF13B that Transports VEGFR2 to Plasmalemma in Endothelial Cells.

Yamada KH, Kang H, Malik AB.

Am J Pathol. 2017 Jan;187(1):214-224. doi: 10.1016/j.ajpath.2016.09.010. Epub 2016 Nov 15. Erratum in: Am J Pathol. 2018 Aug;188(8):1934.

38.

Oxidant Sensing by TRPM2 Inhibits Neutrophil Migration and Mitigates Inflammation.

Wang G, Cao L, Liu X, Sieracki NA, Di A, Wen X, Chen Y, Taylor S, Huang X, Tiruppathi C, Zhao YY, Song Y, Gao X, Jin T, Bai C, Malik AB, Xu J.

Dev Cell. 2016 Sep 12;38(5):453-62. doi: 10.1016/j.devcel.2016.07.014. Epub 2016 Aug 25.

39.

Glutamine Metabolism Regulates the Pluripotency Transcription Factor OCT4.

Marsboom G, Zhang GF, Pohl-Avila N, Zhang Y, Yuan Y, Kang H, Hao B, Brunengraber H, Malik AB, Rehman J.

Cell Rep. 2016 Jul 12;16(2):323-332. doi: 10.1016/j.celrep.2016.05.089. Epub 2016 Jun 23.

40.

Using cultured endothelial cells to study endothelial barrier dysfunction: Challenges and opportunities.

Aman J, Weijers EM, van Nieuw Amerongen GP, Malik AB, van Hinsbergh VW.

Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L453-66. doi: 10.1152/ajplung.00393.2015. Epub 2016 Jun 24. Review.

41.

Src-dependent phosphorylation of caveolin-1 Tyr-14 promotes swelling and release of caveolae.

Zimnicka AM, Husain YS, Shajahan AN, Sverdlov M, Chaga O, Chen Z, Toth PT, Klomp J, Karginov AV, Tiruppathi C, Malik AB, Minshall RD.

Mol Biol Cell. 2016 Jul 1;27(13):2090-106. doi: 10.1091/mbc.E15-11-0756. Epub 2016 May 11.

42.

ROS-activated calcium signaling mechanisms regulating endothelial barrier function.

Di A, Mehta D, Malik AB.

Cell Calcium. 2016 Sep;60(3):163-71. doi: 10.1016/j.ceca.2016.02.002. Epub 2016 Feb 17. Review.

43.

Endothelial p110γPI3K Mediates Endothelial Regeneration and Vascular Repair After Inflammatory Vascular Injury.

Huang X, Dai Z, Cai L, Sun K, Cho J, Albertine KH, Malik AB, Schraufnagel DE, Zhao YY.

Circulation. 2016 Mar 15;133(11):1093-103. doi: 10.1161/CIRCULATIONAHA.115.020918. Epub 2016 Feb 2.

44.

Rab11a Mediates Vascular Endothelial-Cadherin Recycling and Controls Endothelial Barrier Function.

Yan Z, Wang ZG, Segev N, Hu S, Minshall RD, Dull RO, Zhang M, Malik AB, Hu G.

Arterioscler Thromb Vasc Biol. 2016 Feb;36(2):339-49. doi: 10.1161/ATVBAHA.115.306549. Epub 2015 Dec 10.

45.

Endothelial β-Catenin Signaling Is Required for Maintaining Adult Blood-Brain Barrier Integrity and Central Nervous System Homeostasis.

Tran KA, Zhang X, Predescu D, Huang X, Machado RF, Göthert JR, Malik AB, Valyi-Nagy T, Zhao YY.

Circulation. 2016 Jan 12;133(2):177-86. doi: 10.1161/CIRCULATIONAHA.115.015982. Epub 2015 Nov 4.

46.

NOS1-derived nitric oxide promotes NF-κB transcriptional activity through inhibition of suppressor of cytokine signaling-1.

Baig MS, Zaichick SV, Mao M, de Abreu AL, Bakhshi FR, Hart PC, Saqib U, Deng J, Chatterjee S, Block ML, Vogel SM, Malik AB, Consolaro ME, Christman JW, Minshall RD, Gantner BN, Bonini MG.

J Exp Med. 2015 Sep 21;212(10):1725-38. doi: 10.1084/jem.20140654. Epub 2015 Aug 31.

47.

Histone Demethylases KDM4A and KDM4C Regulate Differentiation of Embryonic Stem Cells to Endothelial Cells.

Wu L, Wary KK, Revskoy S, Gao X, Tsang K, Komarova YA, Rehman J, Malik AB.

Stem Cell Reports. 2015 Jul 14;5(1):10-21. doi: 10.1016/j.stemcr.2015.05.016. Epub 2015 Jun 25.

48.

Microtubule-Associated Protein EB3 Regulates IP3 Receptor Clustering and Ca(2+) Signaling in Endothelial Cells.

Geyer M, Huang F, Sun Y, Vogel SM, Malik AB, Taylor CW, Komarova YA.

Cell Rep. 2015 Jul 7;12(1):79-89. doi: 10.1016/j.celrep.2015.06.001. Epub 2015 Jun 25.

49.

Rac1 functions as a reversible tension modulator to stabilize VE-cadherin trans-interaction.

Daneshjou N, Sieracki N, van Nieuw Amerongen GP, Conway DE, Schwartz MA, Komarova YA, Malik AB.

J Cell Biol. 2015 Apr 13;209(1):181. doi: 10.1083/jcb.20140910803202015c. Epub 2015 Apr 6. No abstract available.

50.

p120-catenin expressed in alveolar type II cells is essential for the regulation of lung innate immune response.

Chignalia AZ, Vogel SM, Reynolds AB, Mehta D, Dull RO, Minshall RD, Malik AB, Liu Y.

Am J Pathol. 2015 May;185(5):1251-63. doi: 10.1016/j.ajpath.2015.01.022. Epub 2015 Mar 13.

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