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Application of Invertase Immobilized on Chitosan Using Glutaraldehyde or Tris(Hydroxymethyl)Phosphine as Cross-Linking Agent to Produce Bioethanol.

Malhotra I, Basir SF.

Appl Biochem Biotechnol. 2020 Jan 6. doi: 10.1007/s12010-019-03162-3. [Epub ahead of print]


Immobilization of invertase in calcium alginate and calcium alginate-kappa-carrageenan beads and its application in bioethanol production.

Malhotra I, Basir SF.

Prep Biochem Biotechnol. 2020 Jan 3:1-10. doi: 10.1080/10826068.2019.1709979. [Epub ahead of print]


Mobile obstacles accelerate and inhibit the bundle formation in two-patch colloidal particle.

Malhotra I, Babu SB.

J Chem Phys. 2019 Aug 28;151(8):084901. doi: 10.1063/1.5110777.


Early Childhood Anemia in a Birth Cohort in Coastal Kenya: Links to Infection and Nutrition.

Kao J, Mutuku F, Martin S, Lee J, Mwandi J, Mukoko D, Malhotra I, King CH, LaBeaud AD.

Am J Trop Med Hyg. 2019 Jul;101(1):242-252. doi: 10.4269/ajtmh.17-0688.


Encoding biological recognition in a bicomponent cell-membrane mimic.

Rodriguez-Emmenegger C, Xiao Q, Kostina NY, Sherman SE, Rahimi K, Partridge BE, Li S, Sahoo D, Reveron Perez AM, Buzzacchera I, Han H, Kerzner M, Malhotra I, Möller M, Wilson CJ, Good MC, Goulian M, Baumgart T, Klein ML, Percec V.

Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5376-5382. doi: 10.1073/pnas.1821924116. Epub 2019 Feb 28.


Parasitic infections during pregnancy need not affect infant antibody responses to early vaccination against Streptococcus pneumoniae, diphtheria, or Haemophilus influenzae type B.

McKittrick ND, Malhotra IJ, Vu DM, Boothroyd DB, Lee J, Krystosik AR, Mutuku FM, King CH, LaBeaud AD.

PLoS Negl Trop Dis. 2019 Feb 28;13(2):e0007172. doi: 10.1371/journal.pntd.0007172. eCollection 2019 Feb.


HIV, Cytomegalovirus, and Malaria Infections during Pregnancy Lead to Inflammation and Shifts in Memory B Cell Subsets in Kenyan Neonates.

Yeo KT, Embury P, Anderson T, Mungai P, Malhotra I, King C, Kazura J, Dent A.

J Immunol. 2019 Mar 1;202(5):1465-1478. doi: 10.4049/jimmunol.1801024. Epub 2019 Jan 23.


Nasopharyngeal Carriage of Streptococcus pneumoniae in Children in Coastal Kenya.

Heath CJ, Nayakwadi-Singer M, King CH, Malhotra I, Mutuku F, Mukoko D, LaBeaud AD.

Am J Trop Med Hyg. 2018 Apr;98(4):1046-1050. doi: 10.4269/ajtmh.16-0813. Epub 2018 Feb 22.


Cord Blood Antiparasite Interleukin 10 as a Risk Marker for Compromised Vaccine Immunogenicity in Early Childhood.

Malhotra I, LaBeaud AD, Morris N, McKibben M, Mungai P, Muchiri E, King CL, King CH.

J Infect Dis. 2018 Apr 11;217(9):1426-1434. doi: 10.1093/infdis/jiy047.


Identification of highly-protective combinations of Plasmodium vivax recombinant proteins for vaccine development.

França CT, White MT, He WQ, Hostetler JB, Brewster J, Frato G, Malhotra I, Gruszczyk J, Huon C, Lin E, Kiniboro B, Yadava A, Siba P, Galinski MR, Healer J, Chitnis C, Cowman AF, Takashima E, Tsuboi T, Tham WH, Fairhurst RM, Rayner JC, King CL, Mueller I.

Elife. 2017 Sep 26;6. pii: e28673. doi: 10.7554/eLife.28673.


Syndrome of Inappropriate Antidiuretic Hormone Consecutive to treatment with Ciprofloxacin.

Kumar V, Malhotra I, Shankar S, Kupfer Y.

Am J Ther. 2018 Nov/Dec;25(6):e684-e685. doi: 10.1097/MJT.0000000000000642. No abstract available.


Parasitic Infections in Pregnancy Decrease Placental Transfer of Antipneumococcus Antibodies.

McKittrick ND, Vu DM, Malhotra I, King CH, Mutuku F, LaBeaud AD.

Clin Vaccine Immunol. 2017 Jun 5;24(6). pii: e00039-17. doi: 10.1128/CVI.00039-17. Print 2017 Jun.


Pneumococcal Vaccine Response After Exposure to Parasites in Utero, in Infancy, or Mid-Childhood.

Nayakwadi Singer M, Heath C, Muinde J, Gildengorin V, Mutuku FM, Vu D, Mukoko D, King CL, Malhotra IJ, King CH, LaBeaud AD.

Pediatrics. 2017 Apr;139(4). pii: e20162781. doi: 10.1542/peds.2016-2781. Epub 2017 Mar 16.


Protective Effect of Chronic Schistosomiasis in Baboons Coinfected with Schistosoma mansoni and Plasmodium knowlesi.

Nyakundi RK, Nyamongo O, Maamun J, Akinyi M, Mulei I, Farah IO, Blankenship D, Grimberg B, Hau J, Malhotra I, Ozwara H, King CL, Kariuki TM.

Infect Immun. 2016 Apr 22;84(5):1320-1330. doi: 10.1128/IAI.00490-15. Print 2016 May.


Contrasting Patterns of Serologic and Functional Antibody Dynamics to Plasmodium falciparum Antigens in a Kenyan Birth Cohort.

Dent AE, Malhotra I, Wang X, Babineau D, Yeo KT, Anderson T, Kimmel RJ, Angov E, Lanar DE, Narum D, Dutta S, Richards J, Beeson JG, Crabb BS, Cowman AF, Horii T, Muchiri E, Mungai PL, King CL, Kazura JW.

Clin Vaccine Immunol. 2015 Dec 9;23(2):104-16. doi: 10.1128/CVI.00452-15. Print 2016 Feb.


Parasitism in Children Aged Three Years and Under: Relationship between Infection and Growth in Rural Coastal Kenya.

LaBeaud AD, Nayakwadi Singer M, McKibben M, Mungai P, Muchiri EM, McKibben E, Gildengorin G, Sutherland LJ, King CH, King CL, Malhotra I.

PLoS Negl Trop Dis. 2015 May 21;9(5):e0003721. doi: 10.1371/journal.pntd.0003721. eCollection 2015 May.


Age-Stratified Profiles of Serum IL-6, IL-10, and TNF-α Cytokines Among Kenyan Children with Schistosoma haematobium, Plasmodium falciparum, and Other Chronic Parasitic Co-Infections.

Bustinduy AL, Sutherland LJ, Chang-Cojulun A, Malhotra I, DuVall AS, Fairley JK, Mungai PL, Muchiri EM, Mutuku FM, Kitron U, King CH.

Am J Trop Med Hyg. 2015 May;92(5):945-51. doi: 10.4269/ajtmh.14-0444. Epub 2015 Mar 9.


Effect of antenatal parasitic infections on anti-vaccine IgG levels in children: a prospective birth cohort study in Kenya.

Malhotra I, McKibben M, Mungai P, McKibben E, Wang X, Sutherland LJ, Muchiri EM, King CH, King CL, LaBeaud AD.

PLoS Negl Trop Dis. 2015 Jan 15;9(1):e0003466. doi: 10.1371/journal.pntd.0003466. eCollection 2015 Jan.


The association of parasitic infections in pregnancy and maternal and fetal anemia: a cohort study in coastal Kenya.

McClure EM, Meshnick SR, Mungai P, Malhotra I, King CL, Goldenberg RL, Hudgens MG, Siega-Riz AM, Dent AE.

PLoS Negl Trop Dis. 2014 Feb 27;8(2):e2724. doi: 10.1371/journal.pntd.0002724. eCollection 2014 Feb.


Development of a specimen-sparing multichannel bead assay to detect antiparasite IgG4 for the diagnosis of Schistosoma and Wuchereria infections on the coast of Kenya.

DuVall AS, Fairley JK, Sutherland L, Bustinduy AL, Mungai PL, Muchiri EM, Malhotra I, Kitron U, King CH.

Am J Trop Med Hyg. 2014 Apr;90(4):638-45. doi: 10.4269/ajtmh.13-0292. Epub 2014 Feb 10.


Unpredictable nature of tolvaptan in treatment of hypervolemic hyponatremia: case review on role of vaptans.

Malhotra I, Gopinath S, Janga KC, Greenberg S, Sharma SK, Tarkovsky R.

Case Rep Endocrinol. 2014;2014:807054. doi: 10.1155/2014/807054. Epub 2014 Jan 8.


Marked decline in malaria prevalence among pregnant women and their offspring from 1996 to 2010 on the south Kenyan Coast.

Kalayjian BC, Malhotra I, Mungai P, Holding P, King CL.

Am J Trop Med Hyg. 2013 Dec;89(6):1129-34. doi: 10.4269/ajtmh.13-0250. Epub 2013 Sep 30.


Transplacentally transferred functional antibodies against Plasmodium falciparum decrease with age.

Wilson PT, Malhotra I, Mungai P, King CL, Dent AE.

Acta Trop. 2013 Oct;128(1):149-53. doi: 10.1016/j.actatropica.2013.07.018. Epub 2013 Jul 30.


Birthweight in offspring of mothers with high prevalence of helminth and malaria infection in coastal Kenya.

Fairley JK, Bisanzio D, King CH, Kitron U, Mungai P, Muchiri E, King CL, Malhotra I.

Am J Trop Med Hyg. 2013 Jan;88(1):48-53. doi: 10.4269/ajtmh.2012.12-0371. Epub 2012 Nov 19. Erratum in: Am J Trop Med Hyg. 2014 Dec;91(6):1284.


In utero activation of fetal memory T cells alters host regulatory gene expression and affects HIV susceptibility.

Steiner KL, Malhotra I, Mungai PL, Muchiri EM, Dent AE, King CL.

Virology. 2012 Mar 30;425(1):23-30. doi: 10.1016/j.virol.2012.01.003. Epub 2012 Jan 26.


Serologic evidence of arboviral infections among humans in Kenya.

Sutherland LJ, Cash AA, Huang YJ, Sang RC, Malhotra I, Moormann AM, King CL, Weaver SC, King CH, LaBeaud AD.

Am J Trop Med Hyg. 2011 Jul;85(1):158-61. doi: 10.4269/ajtmh.2011.10-0203.


Human cord blood CD4+CD25hi regulatory T cells suppress prenatally acquired T cell responses to Plasmodium falciparum antigens.

Mackroth MS, Malhotra I, Mungai P, Koech D, Muchiri E, King CL.

J Immunol. 2011 Mar 1;186(5):2780-91. doi: 10.4049/jimmunol.1001188. Epub 2011 Jan 28.


Fetal immune activation to malaria antigens enhances susceptibility to in vitro HIV infection in cord blood mononuclear cells.

Steiner K, Myrie L, Malhotra I, Mungai P, Muchiri E, Dent A, King CL.

J Infect Dis. 2010 Sep 15;202(6):899-907. doi: 10.1086/655783.


Antibody-dependent transplacental transfer of malaria blood-stage antigen using a human ex vivo placental perfusion model.

May K, Grube M, Malhotra I, Long CA, Singh S, Mandaliya K, Siegmund W, Fusch C, Schneider H, King CL.

PLoS One. 2009 Nov 24;4(11):e7986. doi: 10.1371/journal.pone.0007986.


Can prenatal malaria exposure produce an immune tolerant phenotype? A prospective birth cohort study in Kenya.

Malhotra I, Dent A, Mungai P, Wamachi A, Ouma JH, Narum DL, Muchiri E, Tisch DJ, King CL.

PLoS Med. 2009 Jul;6(7):e1000116. doi: 10.1371/journal.pmed.1000116. Epub 2009 Jul 28.


Do antenatal parasite infections devalue childhood vaccination?

Labeaud AD, Malhotra I, King MJ, King CL, King CH.

PLoS Negl Trop Dis. 2009 May 26;3(5):e442. doi: 10.1371/journal.pntd.0000442. Review.


Fine specificity of neonatal lymphocytes to an abundant malaria blood-stage antigen: epitope mapping of Plasmodium falciparum MSP1(33).

Malhotra I, Wamachi AN, Mungai PL, Mzungu E, Koech D, Muchiri E, Moormann AM, King CL.

J Immunol. 2008 Mar 1;180(5):3383-90.


Prenatal malaria immune experience affects acquisition of Plasmodium falciparum merozoite surface protein-1 invasion inhibitory antibodies during infancy.

Dent A, Malhotra I, Mungai P, Muchiri E, Crabb BS, Kazura JW, King CL.

J Immunol. 2006 Nov 15;177(10):7139-45.


Umbilical cord-blood infections with Plasmodium falciparum malaria are acquired antenatally in Kenya.

Malhotra I, Mungai P, Muchiri E, Kwiek JJ, Meshnick SR, King CL.

J Infect Dis. 2006 Jul 15;194(2):176-83. Epub 2006 Jun 12.


Prenatal T cell immunity to Wuchereria bancrofti and its effect on filarial immunity and infection susceptibility during childhood.

Malhotra I, Mungai PL, Wamachi AN, Tisch D, Kioko JM, Ouma JH, Muchiri E, Kazura JW, King CL.

J Infect Dis. 2006 Apr 1;193(7):1005-13. Epub 2006 Feb 22.


The effects of maternal helminth and malaria infections on mother-to-child HIV transmission.

Gallagher M, Malhotra I, Mungai PL, Wamachi AN, Kioko JM, Ouma JH, Muchiri E, King CL.

AIDS. 2005 Nov 4;19(16):1849-55.


Real-time quantitative PCR for determining the burden of Plasmodium falciparum parasites during pregnancy and infancy.

Malhotra I, Dent A, Mungai P, Muchiri E, King CL.

J Clin Microbiol. 2005 Aug;43(8):3630-5.


Distinct Th1- and Th2-Type prenatal cytokine responses to Plasmodium falciparum erythrocyte invasion ligands.

Malhotra I, Mungai P, Muchiri E, Ouma J, Sharma S, Kazura JW, King CL.

Infect Immun. 2005 Jun;73(6):3462-70.


How specific is the immune response to malaria in adults living in endemic areas?

Mannan BA, Patel K, Malhotra I, Ravindran B, Sharma S.

J Vector Borne Dis. 2003 Sep-Dec;40(3-4):84-91.


Influence of maternal filariasis on childhood infection and immunity to Wuchereria bancrofti in Kenya.

Malhotra I, Ouma JH, Wamachi A, Kioko J, Mungai P, Njzovu M, Kazura JW, King CL.

Infect Immun. 2003 Sep;71(9):5231-7.


Acquired immune responses to Plasmodium falciparum merozoite surface protein-1 in the human fetus.

King CL, Malhotra I, Wamachi A, Kioko J, Mungai P, Wahab SA, Koech D, Zimmerman P, Ouma J, Kazura JW.

J Immunol. 2002 Jan 1;168(1):356-64.


Schistosoma haematobium-induced urinary tract morbidity correlates with increased tumor necrosis factor-alpha and diminished interleukin-10 production.

King CL, Malhotra I, Mungai P, Wamachi A, Kioko J, Muchiri E, Ouma JH.

J Infect Dis. 2001 Nov 1;184(9):1176-82. Epub 2001 Oct 12.


Frequent umbilical cord-blood and maternal-blood infections with Plasmodium falciparum, P. malariae, and P. ovale in Kenya.

Tobian AA, Mehlotra RK, Malhotra I, Wamachi A, Mungai P, Koech D, Ouma J, Zimmerman P, King CL.

J Infect Dis. 2000 Aug;182(2):558-63. Epub 2000 Jul 19.


Helminth- and Bacillus Calmette-Guérin-induced immunity in children sensitized in utero to filariasis and schistosomiasis.

Malhotra I, Mungai P, Wamachi A, Kioko J, Ouma JH, Kazura JW, King CL.

J Immunol. 1999 Jun 1;162(11):6843-8.


B cell sensitization to helminthic infection develops in utero in humans.

King CL, Malhotra I, Mungai P, Wamachi A, Kioko J, Ouma JH, Kazura JW.

J Immunol. 1998 Apr 1;160(7):3578-84.


B7-2 requirement for helminth-induced granuloma formation and CD4 type 2 T helper cell cytokine expression.

Subramanian G, Kazura JW, Pearlman E, Jia X, Malhotra I, King CL.

J Immunol. 1997 Jun 15;158(12):5914-20.


In utero exposure to helminth and mycobacterial antigens generates cytokine responses similar to that observed in adults.

Malhotra I, Ouma J, Wamachi A, Kioko J, Mungai P, Omollo A, Elson L, Koech D, Kazura JW, King CL.

J Clin Invest. 1997 Apr 1;99(7):1759-66.


Schistosoma mansoni: protective immunity in IL-4-deficient mice.

King CL, Malhotra I, Jia X.

Exp Parasitol. 1996 Nov;84(2):245-52.


Cytokine control of parasite-specific anergy in human urinary schistosomiasis. IL-10 modulates lymphocyte reactivity.

King CL, Medhat A, Malhotra I, Nafeh M, Helmy A, Khaudary J, Ibrahim S, El-Sherbiny M, Zaky S, Stupi RJ, Brustoski K, Shehata M, Shata MT.

J Immunol. 1996 Jun 15;156(12):4715-21.


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