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Items: 7

1.

Structural Basis for Cooperative Binding of EBNA1 to the Epstein-Barr Virus Dyad Symmetry Minimal Origin of Replication.

Malecka KA, Dheekollu J, Deakyne JS, Wiedmer A, Ramirez UD, Lieberman PM, Messick TE.

J Virol. 2019 Sep 30;93(20). pii: e00487-19. doi: 10.1128/JVI.00487-19. Print 2019 Oct 15.

PMID:
31142669
2.

Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth.

Messick TE, Smith GR, Soldan SS, McDonnell ME, Deakyne JS, Malecka KA, Tolvinski L, van den Heuvel APJ, Gu BW, Cassel JA, Tran DH, Wassermann BR, Zhang Y, Velvadapu V, Zartler ER, Busson P, Reitz AB, Lieberman PM.

Sci Transl Med. 2019 Mar 6;11(482). pii: eaau5612. doi: 10.1126/scitranslmed.aau5612.

PMID:
30842315
3.

Structural and Functional Basis for an EBNA1 Hexameric Ring in Epstein-Barr Virus Episome Maintenance.

Deakyne JS, Malecka KA, Messick TE, Lieberman PM.

J Virol. 2017 Sep 12;91(19). pii: e01046-17. doi: 10.1128/JVI.01046-17. Print 2017 Oct 1.

4.

Identification and characterization of small molecule human papillomavirus E6 inhibitors.

Malecka KA, Fera D, Schultz DC, Hodawadekar S, Reichman M, Donover PS, Murphy ME, Marmorstein R.

ACS Chem Biol. 2014 Jul 18;9(7):1603-12. doi: 10.1021/cb500229d. Epub 2014 Jun 2.

5.

Synergistic activation of p21-activated kinase 1 by phosphatidylinositol 4,5-bisphosphate and Rho GTPases.

Malecka KA, Szentpetery Z, Peterson JR.

J Biol Chem. 2013 Mar 29;288(13):8887-97. doi: 10.1074/jbc.M112.428904. Epub 2013 Feb 7.

6.

Face-to-face, pak-to-pak.

Malecka KA, Peterson JR.

Structure. 2011 Dec 7;19(12):1723-4. doi: 10.1016/j.str.2011.11.007.

7.

Crystal structure of a p53 core tetramer bound to DNA.

Malecka KA, Ho WC, Marmorstein R.

Oncogene. 2009 Jan 22;28(3):325-33. doi: 10.1038/onc.2008.400. Epub 2008 Nov 3.

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