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Items: 1 to 50 of 139

1.

Corrigendum: A 28-Year History of HIV-1 Drug Resistance and Transmission in Washington, DC.

Gibson KM, Steiner MC, Kassaye S, Maldarelli F, Grossman Z, Pérez-Losada M, Crandall KA.

Front Microbiol. 2019 Nov 12;10:2590. doi: 10.3389/fmicb.2019.02590. eCollection 2019.

2.

Combined HIV-1 sequence and integration site analysis informs viral dynamics and allows reconstruction of replicating viral ancestors.

Patro SC, Brandt LD, Bale MJ, Halvas EK, Joseph KW, Shao W, Wu X, Guo S, Murrell B, Wiegand A, Spindler J, Raley C, Hautman C, Sobolewski M, Fennessey CM, Hu WS, Luke B, Hasson JM, Niyongabo A, Capoferri AA, Keele BF, Milush J, Hoh R, Deeks SG, Maldarelli F, Hughes SH, Coffin JM, Rausch JW, Mellors JW, Kearney MF.

Proc Natl Acad Sci U S A. 2019 Nov 27. pii: 201910334. doi: 10.1073/pnas.1910334116. [Epub ahead of print]

PMID:
31776247
3.

Principles Governing Establishment versus Collapse of HIV-1 Cellular Spread.

Hataye JM, Casazza JP, Best K, Liang CJ, Immonen TT, Ambrozak DR, Darko S, Henry AR, Laboune F, Maldarelli F, Douek DC, Hengartner NW, Yamamoto T, Keele BF, Perelson AS, Koup RA.

Cell Host Microbe. 2019 Dec 11;26(6):748-763.e20. doi: 10.1016/j.chom.2019.10.006. Epub 2019 Nov 21.

PMID:
31761718
4.

HIV Infected T Cells Can Proliferate in vivo Without Inducing Expression of the Integrated Provirus.

Musick A, Spindler J, Boritz E, Pérez L, Crespo-Vélez D, Patro SC, Sobolewski MD, Bale MJ, Reid C, Keele BF, Capoferri A, Shao W, Wiegand A, Simonetti FR, Mellors JW, Hughes SH, Coffin JM, Maldarelli F, Kearney MF.

Front Microbiol. 2019 Oct 1;10:2204. doi: 10.3389/fmicb.2019.02204. eCollection 2019.

5.

Pilot Trial AMC-063: Safety and Efficacy of Bortezomib in AIDS-associated Kaposi Sarcoma.

Reid EG, Suazo A, Lensing SY, Dittmer DP, Ambinder RF, Maldarelli F, Gorelick RJ, Aboulafia DM, Mitsuyasu R, Dickson MA, Wachsman W.

Clin Cancer Res. 2019 Oct 17. pii: clincanres.1044.2019. doi: 10.1158/1078-0432.CCR-19-1044. [Epub ahead of print]

PMID:
31624104
6.

Effector memory differentiation increases detection of replication-competent HIV-l in resting CD4+ T cells from virally suppressed individuals.

Wonderlich ER, Subramanian K, Cox B, Wiegand A, Lackman-Smith C, Bale MJ, Stone M, Hoh R, Kearney MF, Maldarelli F, Deeks SG, Busch MP, Ptak RG, Kulpa DA.

PLoS Pathog. 2019 Oct 14;15(10):e1008074. doi: 10.1371/journal.ppat.1008074. eCollection 2019 Oct.

7.

No evidence of ongoing HIV replication or compartmentalization in tissues during combination antiretroviral therapy: Implications for HIV eradication.

Bozzi G, Simonetti FR, Watters SA, Anderson EM, Gouzoulis M, Kearney MF, Rote P, Lange C, Shao W, Gorelick R, Fullmer B, Kumar S, Wank S, Hewitt S, Kleiner DE, Hattori J, Bale MJ, Hill S, Bell J, Rehm C, Grossman Z, Yarchoan R, Uldrick T, Maldarelli F.

Sci Adv. 2019 Sep 25;5(9):eaav2045. doi: 10.1126/sciadv.aav2045. eCollection 2019 Sep.

8.

Transmission Dynamics of HIV Subtype A in Tel Aviv, Israel: Implications for HIV Spread and Eradication.

Grossman Z, Avidor B, Girshengoren S, Katchman E, Maldarelli F, Turner D.

Open Forum Infect Dis. 2019 Jul 1;6(7). pii: ofz304. doi: 10.1093/ofid/ofz304.

9.

8-Day Inpatient Directly Observed Therapy for ART Failure: A Tool For Preventing Unnecessary ART Changes and Optimizing Adherence Support.

Winchester NE, Maldarelli F, Mejia Y, Dee N, Dewar R, Laidlaw E, Kuriakose SS, Stoll P, Proschan M, Lane HC, Pau AK.

Clin Infect Dis. 2019 Jul 11. pii: ciz590. doi: 10.1093/cid/ciz590. [Epub ahead of print]

PMID:
31298273
10.

Clones of infected cells arise early in HIV-infected individuals.

Coffin JM, Wells DW, Zerbato JM, Kuruc JD, Guo S, Luke BT, Eron JJ, Bale M, Spindler J, Simonetti FR, Hill S, Kearney MF, Maldarelli F, Wu X, Mellors JW, Hughes SH.

JCI Insight. 2019 Jun 20;4(12). pii: 128432. doi: 10.1172/jci.insight.128432. eCollection 2019 Jun 20.

11.

Donor Small-Droplet Macrovesicular Steatosis Affects Liver Transplant Outcome in HCV-Negative Recipients.

Ferri F, Lai Q, Molinaro A, Poli E, Parlati L, Lattanzi B, Mennini G, Melandro F, Pugliese F, Maldarelli F, Corsi A, Riminucci M, Merli M, Rossi M, Ginanni Corradini S.

Can J Gastroenterol Hepatol. 2019 May 2;2019:5862985. doi: 10.1155/2019/5862985. eCollection 2019.

12.

Low-level alternative tRNA priming of reverse transcription of HIV-1 and SIV in vivo.

Fennessey CM, Camus C, Immonen TT, Reid C, Maldarelli F, Lifson JD, Keele BF.

Retrovirology. 2019 Apr 4;16(1):11. doi: 10.1186/s12977-019-0473-2.

13.

A 28-Year History of HIV-1 Drug Resistance and Transmission in Washington, DC.

Gibson KM, Steiner MC, Kassaye S, Maldarelli F, Grossman Z, Pérez-Losada M, Crandall KA.

Front Microbiol. 2019 Mar 8;10:369. doi: 10.3389/fmicb.2019.00369. eCollection 2019. Erratum in: Front Microbiol. 2019 Nov 12;10:2590.

14.

Safety and efficacy of an oncolytic viral strategy using bortezomib with ICE/R in relapsed/refractory HIV-positive lymphomas.

Reid EG, Looney D, Maldarelli F, Noy A, Henry D, Aboulafia D, Ramos JC, Sparano J, Ambinder RF, Lee J, Cesarman E, Yahyaei S, Mitsuyasu R, Wachsman W; AIDS Malignancy Consortium.

Blood Adv. 2018 Dec 26;2(24):3618-3626. doi: 10.1182/bloodadvances.2018022095.

15.

Rapid Development of High-Level Resistance to Dolutegravir With Emergence of T97A Mutation in 2 Treatment-Experienced Individuals With Baseline Partial Sensitivity to Dolutegravir.

George JM, Kuriakose SS, Dee N, Stoll P, Lalani T, Dewar R, Khan MA, Rehman MT, Grossman Z, Maldarelli F, Pau AK.

Open Forum Infect Dis. 2018 Sep 8;5(10):ofy221. doi: 10.1093/ofid/ofy221. eCollection 2018 Oct.

16.

Metagenomic Discovery of 83 New Human Papillomavirus Types in Patients with Immunodeficiency.

Pastrana DV, Peretti A, Welch NL, Borgogna C, Olivero C, Badolato R, Notarangelo LD, Gariglio M, FitzGerald PC, McIntosh CE, Reeves J, Starrett GJ, Bliskovsky V, Velez D, Brownell I, Yarchoan R, Wyvill KM, Uldrick TS, Maldarelli F, Lisco A, Sereti I, Gonzalez CM, Androphy EJ, McBride AA, Van Doorslaer K, Garcia F, Dvoretzky I, Liu JS, Han J, Murphy PM, McDermott DH, Buck CB.

mSphere. 2018 Dec 12;3(6). pii: e00645-18. doi: 10.1128/mSphereDirect.00645-18.

17.

The role of integration and clonal expansion in HIV infection: live long and prosper.

Anderson EM, Maldarelli F.

Retrovirology. 2018 Oct 23;15(1):71. doi: 10.1186/s12977-018-0448-8. Review.

18.

Ongoing HIV Replication During ART Reconsidered.

Kearney MF, Wiegand A, Shao W, McManus WR, Bale MJ, Luke B, Maldarelli F, Mellors JW, Coffin JM.

Open Forum Infect Dis. 2017 Sep 19;4(3):ofx173. doi: 10.1093/ofid/ofx173. eCollection 2017 Summer.

19.

Quantification of HIV DNA Using Droplet Digital PCR Techniques.

Anderson EM, Maldarelli F.

Curr Protoc Microbiol. 2018 Nov;51(1):e62. doi: 10.1002/cpmc.62. Epub 2018 Sep 25.

20.

Early Presence of HIV-1 Subtype C in Washington, D.C.

Grossman Z, Rico SV, Cone K, Shao W, Rehm C, Jones S, Bozzi G, Dean S, Dewar R, Rehman T, Purdy J, Hadigan C, Pau AK, Maldarelli F.

AIDS Res Hum Retroviruses. 2018 Aug;34(8):680-684. doi: 10.1089/AID.2018.0041.

21.

Collaborative update of a rule-based expert system for HIV-1 genotypic resistance test interpretation.

Paredes R, Tzou PL, van Zyl G, Barrow G, Camacho R, Carmona S, Grant PM, Gupta RK, Hamers RL, Harrigan PR, Jordan MR, Kantor R, Katzenstein DA, Kuritzkes DR, Maldarelli F, Otelea D, Wallis CL, Schapiro JM, Shafer RW.

PLoS One. 2017 Jul 28;12(7):e0181357. doi: 10.1371/journal.pone.0181357. eCollection 2017.

22.

Decreased Absorption of Dolutegravir and Tenofovir Disoproxil Fumarate, But Not Emtricitabine, in an HIV-Infected Patient Following Oral and Jejunostomy-Tube Administration.

Brooks KM, Garrett KL, Kuriakose SS, George JM, Balba G, Bailey B, Anderson M, Lane HC, Maldarelli F, Pau AK.

Pharmacotherapy. 2017 Aug;37(8):e82-e89. doi: 10.1002/phar.1960. Epub 2017 Jul 18.

23.

Ultrasensitive single-genome sequencing: accurate, targeted, next generation sequencing of HIV-1 RNA.

Boltz VF, Rausch J, Shao W, Hattori J, Luke B, Maldarelli F, Mellors JW, Kearney MF, Coffin JM.

Retrovirology. 2016 Dec 20;13(1):87. doi: 10.1186/s12977-016-0321-6.

24.

Pomalidomide for Symptomatic Kaposi's Sarcoma in People With and Without HIV Infection: A Phase I/II Study.

Polizzotto MN, Uldrick TS, Wyvill KM, Aleman K, Peer CJ, Bevans M, Sereti I, Maldarelli F, Whitby D, Marshall V, Goncalves PH, Khetani V, Figg WD, Steinberg SM, Zeldis JB, Yarchoan R.

J Clin Oncol. 2016 Dec;34(34):4125-4131. Epub 2016 Oct 31. Erratum in: J Clin Oncol. 2018 Jul 1;36(19):2008.

25.

Multiple Origins of Virus Persistence during Natural Control of HIV Infection.

Boritz EA, Darko S, Swaszek L, Wolf G, Wells D, Wu X, Henry AR, Laboune F, Hu J, Ambrozak D, Hughes MS, Hoh R, Casazza JP, Vostal A, Bunis D, Nganou-Makamdop K, Lee JS, Migueles SA, Koup RA, Connors M, Moir S, Schacker T, Maldarelli F, Hughes SH, Deeks SG, Douek DC.

Cell. 2016 Aug 11;166(4):1004-1015. doi: 10.1016/j.cell.2016.06.039. Epub 2016 Jul 21.

26.

APOBEC3 proteins can copackage and comutate HIV-1 genomes.

Desimmie BA, Burdick RC, Izumi T, Doi H, Shao W, Alvord WG, Sato K, Koyanagi Y, Jones S, Wilson E, Hill S, Maldarelli F, Hu WS, Pathak VK.

Nucleic Acids Res. 2016 Sep 19;44(16):7848-65. doi: 10.1093/nar/gkw653. Epub 2016 Jul 20.

27.

Sequential CCR5-Tropic HIV-1 Reactivation from Distinct Cellular Reservoirs following Perturbation of Elite Control.

Watters SA, Mlcochova P, Maldarelli F, Goonetilleke N, Pillay D, Gupta RK.

PLoS One. 2016 Jul 12;11(7):e0158854. doi: 10.1371/journal.pone.0158854. eCollection 2016.

28.

Retrovirus Integration Database (RID): a public database for retroviral insertion sites into host genomes.

Shao W, Shan J, Kearney MF, Wu X, Maldarelli F, Mellors JW, Luke B, Coffin JM, Hughes SH.

Retrovirology. 2016 Jul 4;13(1):47. doi: 10.1186/s12977-016-0277-6.

29.

Transmitted HIV Drug Resistance Is High and Longstanding in Metropolitan Washington, DC.

Kassaye SG, Grossman Z, Balamane M, Johnston-White B, Liu C, Kumar P, Young M, Sneller MC, Sereti I, Dewar R, Rehm C, Meyer W 3rd, Shafer R, Katzenstein D, Maldarelli F.

Clin Infect Dis. 2016 Sep 15;63(6):836-843. doi: 10.1093/cid/ciw382. Epub 2016 Jun 15.

30.

Tenofovir alafenamide as part of a salvage regimen in a patient with multi-drug resistant HIV and tenofovir-DF-associated renal tubulopathy.

Mikula JM, Manion MM, Maldarelli F, Suarez LM, Norman-Wheeler JF, Ober AG, Dewar RL, Kopp JB, Lane HC, Pau AK.

Antivir Ther. 2016;21(6):553-558. doi: 10.3851/IMP3040. Epub 2016 Mar 8.

31.

Clonally expanded CD4+ T cells can produce infectious HIV-1 in vivo.

Simonetti FR, Sobolewski MD, Fyne E, Shao W, Spindler J, Hattori J, Anderson EM, Watters SA, Hill S, Wu X, Wells D, Su L, Luke BT, Halvas EK, Besson G, Penrose KJ, Yang Z, Kwan RW, Van Waes C, Uldrick T, Citrin DE, Kovacs J, Polis MA, Rehm CA, Gorelick R, Piatak M, Keele BF, Kearney MF, Coffin JM, Hughes SH, Mellors JW, Maldarelli F.

Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1883-8. doi: 10.1073/pnas.1522675113. Epub 2016 Feb 8.

32.

The role of HIV integration in viral persistence: no more whistling past the proviral graveyard.

Maldarelli F.

J Clin Invest. 2016 Feb;126(2):438-47. doi: 10.1172/JCI80564. Epub 2016 Feb 1. Review.

33.

Characteristics and Outcome of Patients Diagnosed With HIV at Older Age.

Asher I, Guri KM, Elbirt D, Bezalel SR, Maldarelli F, Mor O, Grossman Z, Sthoeger ZM.

Medicine (Baltimore). 2016 Jan;95(1):e2327. doi: 10.1097/MD.0000000000002327.

34.

A Population-Structured HIV Epidemic in Israel: Roles of Risk and Ethnicity.

Grossman Z, Avidor B, Mor Z, Chowers M, Levy I, Shahar E, Riesenberg K, Sthoeger Z, Maayan S, Shao W, Lorber M, Olstein-Pops K, Elbirt D, Elinav H, Asher I, Averbuch D, Istomin V, Gottesman BS, Kedem E, Girshengorn S, Kra-Oz Z, Shemer Avni Y, Radian Sade S, Turner D, Maldarelli F.

PLoS One. 2015 Aug 24;10(8):e0135061. doi: 10.1371/journal.pone.0135061. eCollection 2015.

36.

Independent lung ventilation in the postoperative management of single lung transplantation: case report.

Ruberto Franco F, Zullino V, Congi P, Magnanimi E, Bernardinetti M, Paglialunga G, Maldarelli F, Diso D, Venuta F, Pugliese F.

Transplant Proc. 2014 Sep;46(7):2357-9. doi: 10.1016/j.transproceed.2014.07.046.

PMID:
25242787
37.

Adaptive support ventilation versus synchronized intermittent mandatory ventilation with pressure support in weaning patients after orthotopic liver transplantation.

Celli P, Privato E, Ianni S, Babetto C, D'Arena C, Guglielmo N, Maldarelli F, Paglialunga G, Rossi M, Berloco PB, Ruberto F, Pugliese F.

Transplant Proc. 2014 Sep;46(7):2272-8. doi: 10.1016/j.transproceed.2014.06.046. Epub 2014 Aug 20.

PMID:
25150607
38.

HIV-1 infection leads to increased transcription of human endogenous retrovirus HERV-K (HML-2) proviruses in vivo but not to increased virion production.

Bhardwaj N, Maldarelli F, Mellors J, Coffin JM.

J Virol. 2014 Oct;88(19):11108-20. doi: 10.1128/JVI.01623-14. Epub 2014 Jul 23.

39.

HIV latency. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells.

Maldarelli F, Wu X, Su L, Simonetti FR, Shao W, Hill S, Spindler J, Ferris AL, Mellors JW, Kearney MF, Coffin JM, Hughes SH.

Science. 2014 Jul 11;345(6193):179-83. doi: 10.1126/science.1254194. Epub 2014 Jun 26.

40.

Plasma fatty acid lipidome is associated with cirrhosis prognosis and graft damage in liver transplantation.

Ginanni Corradini S, Zerbinati C, Maldarelli F, Palmaccio G, Parlati L, Bottaccioli AG, Molinaro A, Poli E, Boaz M, Serviddio G, Mennini G, Corsi A, Bianco P, Rossi M, Iuliano L.

Am J Clin Nutr. 2014 Aug;100(2):600-8. doi: 10.3945/ajcn.113.074427. Epub 2014 Jun 25.

PMID:
24965302
41.

PAPNC, a novel method to calculate nucleotide diversity from large scale next generation sequencing data.

Shao W, Kearney MF, Boltz VF, Spindler JE, Mellors JW, Maldarelli F, Coffin JM.

J Virol Methods. 2014 Jul;203:73-80. doi: 10.1016/j.jviromet.2014.03.008. Epub 2014 Mar 26.

42.

Lack of detectable HIV-1 molecular evolution during suppressive antiretroviral therapy.

Kearney MF, Spindler J, Shao W, Yu S, Anderson EM, O'Shea A, Rehm C, Poethke C, Kovacs N, Mellors JW, Coffin JM, Maldarelli F.

PLoS Pathog. 2014 Mar 20;10(3):e1004010. doi: 10.1371/journal.ppat.1004010. eCollection 2014 Mar.

43.

Activation of HIV-1 from latent infection via synergy of RUNX1 inhibitor Ro5-3335 and SAHA.

Klase Z, Yedavalli VS, Houzet L, Perkins M, Maldarelli F, Brenchley J, Strebel K, Liu P, Jeang KT.

PLoS Pathog. 2014 Mar 20;10(3):e1003997. doi: 10.1371/journal.ppat.1003997. eCollection 2014 Mar.

44.

Rational development of radiopharmaceuticals for HIV-1.

Lau CY, Maldarelli F, Eckelman WC, Neumann RD.

Nucl Med Biol. 2014 Apr;41(4):299-308. doi: 10.1016/j.nucmedbio.2014.01.005. Epub 2014 Jan 17. Review.

45.

Single-copy quantification of HIV-1 in clinical samples.

Wiegand A, Maldarelli F.

Methods Mol Biol. 2014;1087:251-60. doi: 10.1007/978-1-62703-670-2_20.

PMID:
24158828
46.

PNPLA3 I148M (rs738409) genetic variant and age at onset of at-risk alcohol consumption are independent risk factors for alcoholic cirrhosis.

Burza MA, Molinaro A, Attilia ML, Rotondo C, Attilia F, Ceccanti M, Ferri F, Maldarelli F, Maffongelli A, De Santis A, Attili AF, Romeo S, Ginanni Corradini S.

Liver Int. 2014 Apr;34(4):514-20. doi: 10.1111/liv.12310. Epub 2013 Sep 19.

47.

Limited nucleotide changes in the Rev response element (RRE) during HIV-1 infection alter overall Rev-RRE activity and Rev multimerization.

Sloan EA, Kearney MF, Gray LR, Anastos K, Daar ES, Margolick J, Maldarelli F, Hammarskjold ML, Rekosh D.

J Virol. 2013 Oct;87(20):11173-86. doi: 10.1128/JVI.01392-13. Epub 2013 Aug 7.

48.

Single cell analysis of lymph node tissue from HIV-1 infected patients reveals that the majority of CD4+ T-cells contain one HIV-1 DNA molecule.

Josefsson L, Palmer S, Faria NR, Lemey P, Casazza J, Ambrozak D, Kearney M, Shao W, Kottilil S, Sneller M, Mellors J, Coffin JM, Maldarelli F.

PLoS Pathog. 2013;9(6):e1003432. doi: 10.1371/journal.ppat.1003432. Epub 2013 Jun 20.

49.

HIV populations are large and accumulate high genetic diversity in a nonlinear fashion.

Maldarelli F, Kearney M, Palmer S, Stephens R, Mican J, Polis MA, Davey RT, Kovacs J, Shao W, Rock-Kress D, Metcalf JA, Rehm C, Greer SE, Lucey DL, Danley K, Alter H, Mellors JW, Coffin JM.

J Virol. 2013 Sep;87(18):10313-23. doi: 10.1128/JVI.01225-12. Epub 2013 May 15.

50.

Evaluation of sequence ambiguities of the HIV-1 pol gene as a method to identify recent HIV-1 infection in transmitted drug resistance surveys.

Andersson E, Shao W, Bontell I, Cham F, Cuong do D, Wondwossen A, Morris L, Hunt G, Sönnerborg A, Bertagnolio S, Maldarelli F, Jordan MR.

Infect Genet Evol. 2013 Aug;18:125-31. doi: 10.1016/j.meegid.2013.03.050. Epub 2013 Apr 11.

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