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Items: 1 to 50 of 91

1.

Chagas disease vaccine design: the search for an efficient Trypanosoma cruzi immune-mediated control.

Bivona AE, Alberti AS, Cerny N, Trinitario SN, Malchiodi EL.

Biochim Biophys Acta Mol Basis Dis. 2020 Jan 2:165658. doi: 10.1016/j.bbadis.2019.165658. [Epub ahead of print] Review.

PMID:
31904415
2.

Oxidation of proline from the cyclin-binding motif in maize CDKA;1 results in lower affinity with its cyclin regulatory subunit.

Méndez AAE, Pena LB, Curto LM, Fernández MM, Malchiodi EL, Garza-Aguilar SM, Vázquez-Ramos JM, Gallego SM.

Phytochemistry. 2020 Jan;169:112165. doi: 10.1016/j.phytochem.2019.112165. Epub 2019 Oct 11.

PMID:
31610323
3.

Recombinant Cysteine Proteinase B from Leishmania braziliensis and Its Domains: Promising Antigens for Serodiagnosis of Cutaneous and Visceral Leishmaniasis in Dogs.

Bivona AE, Czentner L, Sanchez Alberti A, Cerny N, Cardoso Landaburu AC, Nevot C, Estévez O, Marco JD, Basombrio MA, Malchiodi EL, Cazorla SI.

J Clin Microbiol. 2019 Oct 23;57(11). pii: e00819-19. doi: 10.1128/JCM.00819-19. Print 2019 Nov.

PMID:
31434727
4.

Activity of Estafietin and Analogues on Trypanosoma cruzi and Leishmania braziliensis.

Sülsen VP, Lizarraga EF, Elso OG, Cerny N, Sanchez Alberti A, Bivona AE, Malchiodi EL, Cazorla SI, Catalán CAN.

Molecules. 2019 Mar 28;24(7). pii: E1209. doi: 10.3390/molecules24071209.

5.

Preparation of Sesquiterpene Lactone Derivatives: Cytotoxic Activity and Selectivity of Action.

Beer MF, Bivona AE, Sánchez Alberti A, Cerny N, Reta GF, Martín VS, Padrón JM, Malchiodi EL, Sülsen VP, Donadel OJ.

Molecules. 2019 Mar 20;24(6). pii: E1113. doi: 10.3390/molecules24061113.

6.

Trypanosoma cruzi 80 kDa prolyl oligopeptidase (Tc80) as a novel immunogen for Chagas disease vaccine.

Bivona AE, Sánchez Alberti A, Matos MN, Cerny N, Cardoso AC, Morales C, González G, Cazorla SI, Malchiodi EL.

PLoS Negl Trop Dis. 2018 Mar 30;12(3):e0006384. doi: 10.1371/journal.pntd.0006384. eCollection 2018 Mar.

7.

Engineered trivalent immunogen adjuvanted with a STING agonist confers protection against Trypanosoma cruzi infection.

Sanchez Alberti A, Bivona AE, Cerny N, Schulze K, Weißmann S, Ebensen T, Morales C, Padilla AM, Cazorla SI, Tarleton RL, Guzmán CA, Malchiodi EL.

NPJ Vaccines. 2017 Apr 10;2:9. doi: 10.1038/s41541-017-0010-z. eCollection 2017.

8.

Evidence of size-dependent effect of silica micro- and nano-particles on basal and specialized monocyte functions.

De Marzi MC, Saraceno M, Mitarotonda R, Todone M, Fernandez M, Malchiodi EL, Desimone MF.

Ther Deliv. 2017 Dec;8(12):1035-1049. doi: 10.4155/tde-2017-0053.

PMID:
29125067
9.

Assessment of sesquiterpene lactones isolated from Mikania plants species for their potential efficacy against Trypanosoma cruzi and Leishmania sp.

Laurella LC, Cerny N, Bivona AE, Sánchez Alberti A, Giberti G, Malchiodi EL, Martino VS, Catalan CA, Alonso MR, Cazorla SI, Sülsen VP.

PLoS Negl Trop Dis. 2017 Sep 25;11(9):e0005929. doi: 10.1371/journal.pntd.0005929. eCollection 2017 Sep.

10.

Immunization with Tc52 or its amino terminal domain adjuvanted with c-di-AMP induces Th17+Th1 specific immune responses and confers protection against Trypanosoma cruzi.

Matos MN, Cazorla SI, Schulze K, Ebensen T, Guzmán CA, Malchiodi EL.

PLoS Negl Trop Dis. 2017 Feb 24;11(2):e0005300. doi: 10.1371/journal.pntd.0005300. eCollection 2017 Feb.

11.

Kinetic and thermodynamic studies of the interaction between activating and inhibitory Ly49 natural killer receptors and MHC class I molecules.

Romasanta PN, Curto LM, Sarratea MB, Noli Truant S, Antonoglou MB, Fernández Lynch MJ, Delfino JM, Mariuzza RA, Fernández MM, Malchiodi EL.

Biochem J. 2017 Jan 1;474(1):179-194. doi: 10.1042/BCJ20160876. Epub 2016 Nov 9.

PMID:
27831490
12.

MutS regulates access of the error-prone DNA polymerase Pol IV to replication sites: a novel mechanism for maintaining replication fidelity.

Margara LM, Fernández MM, Malchiodi EL, Argaraña CE, Monti MR.

Nucleic Acids Res. 2016 Sep 19;44(16):7700-13. doi: 10.1093/nar/gkw494. Epub 2016 Jun 1.

13.

A prime-boost immunization with Tc52 N-terminal domain DNA and the recombinant protein expressed in Pichia pastoris protects against Trypanosoma cruzi infection.

Matos MN, Sánchez Alberti A, Morales C, Cazorla SI, Malchiodi EL.

Vaccine. 2016 Jun 14;34(28):3243-51. doi: 10.1016/j.vaccine.2016.05.011. Epub 2016 May 10.

PMID:
27177947
14.

Glycosylation-dependent binding of galectin-8 to activated leukocyte cell adhesion molecule (ALCAM/CD166) promotes its surface segregation on breast cancer cells.

Fernández MM, Ferragut F, Cárdenas Delgado VM, Bracalente C, Bravo AI, Cagnoni AJ, Nuñez M, Morosi LG, Quinta HR, Espelt MV, Troncoso MF, Wolfenstein-Todel C, Mariño KV, Malchiodi EL, Rabinovich GA, Elola MT.

Biochim Biophys Acta. 2016 Oct;1860(10):2255-68. doi: 10.1016/j.bbagen.2016.04.019. Epub 2016 Apr 26.

PMID:
27130882
15.

Attenuated Salmonella sp. as a DNA Delivery System for Trypanosoma cruzi Antigens.

Bivona AE, Cerny N, Alberti AS, Cazorla SI, Malchiodi EL.

Methods Mol Biol. 2016;1404:683-95. doi: 10.1007/978-1-4939-3389-1_44.

PMID:
27076330
16.

Coadministration of cruzipain and GM-CSF DNAs, a new immunotherapeutic vaccine against Trypanosoma cruzi infection.

Cerny N, Sánchez Alberti A, Bivona AE, De Marzi MC, Frank FM, Cazorla SI, Malchiodi EL.

Hum Vaccin Immunother. 2016;12(2):438-50. doi: 10.1080/21645515.2015.1078044.

17.

A positive cooperativity binding model between Ly49 natural killer cell receptors and the viral immunoevasin m157. KINETIC AND THERMODYNAMIC STUDIES.

Romasanta PN, Curto LM, Urtasun N, Sarratea MB, Chiappini S, Miranda MV, Delfino JM, Mariuzza RA, Fernández MM, Malchiodi EL.

J Biol Chem. 2015 Aug 14;290(33):20098-9. doi: 10.1074/jbc.A113.532929. No abstract available.

18.

Peptidoglycan recognition protein-peptidoglycan complexes increase monocyte/macrophage activation and enhance the inflammatory response.

De Marzi MC, Todone M, Ganem MB, Wang Q, Mariuzza RA, Fernández MM, Malchiodi EL.

Immunology. 2015 Jul;145(3):429-42. doi: 10.1111/imm.12460. Epub 2015 Apr 16.

19.

Oral multicomponent DNA vaccine delivered by attenuated Salmonella elicited immunoprotection against American trypanosomiasis.

Cazorla SI, Matos MN, Cerny N, Ramirez C, Alberti AS, Bivona AE, Morales C, Guzmán CA, Malchiodi EL.

J Infect Dis. 2015 Mar 1;211(5):698-707. doi: 10.1093/infdis/jiu480. Epub 2014 Aug 25.

PMID:
25160983
20.

Galectin-3 is essential for early wound healing and ventricular remodeling after myocardial infarction in mice.

González GE, Cassaglia P, Noli Truant S, Fernández MM, Wilensky L, Volberg V, Malchiodi EL, Morales C, Gelpi RJ.

Int J Cardiol. 2014 Oct 20;176(3):1423-5. doi: 10.1016/j.ijcard.2014.08.011. Epub 2014 Aug 8. No abstract available.

PMID:
25150483
21.

Tc52 amino-terminal-domain DNA carried by attenuated Salmonella enterica serovar Typhimurium induces protection against a Trypanosoma cruzi lethal challenge.

Matos MN, Cazorla SI, Bivona AE, Morales C, Guzmán CA, Malchiodi EL.

Infect Immun. 2014 Oct;82(10):4265-75. doi: 10.1128/IAI.02190-14. Epub 2014 Jul 28.

22.

A positive cooperativity binding model between Ly49 natural killer cell receptors and the viral immunoevasin m157: kinetic and thermodynamic studies.

Romasanta PN, Curto LM, Urtasun N, Sarratea MB, Chiappini S, Miranda MV, Delfino JM, Mariuzza RA, Fernández MM, Malchiodi EL.

J Biol Chem. 2014 Feb 21;289(8):5083-96. doi: 10.1074/jbc.M113.532929. Epub 2013 Dec 30. Erratum in: J Biol Chem. 2015 Aug 14;290(33):20098-9.

23.

Novel evidence for the specific interaction between cholesterol and α-haemolysin of Escherichia coli.

Vazquez RF, Maté SM, Bakás LS, Fernández MM, Malchiodi EL, Herlax VS.

Biochem J. 2014 Mar 15;458(3):481-9. doi: 10.1042/BJ20131432.

PMID:
24351077
24.

Wingless-type family member 3A triggers neuronal polarization via cross-activation of the insulin-like growth factor-1 receptor pathway.

Bernis ME, Oksdath M, Dupraz S, Nieto Guil A, Fernández MM, Malchiodi EL, Rosso SB, Quiroga S.

Front Cell Neurosci. 2013 Oct 25;7:194. doi: 10.3389/fncel.2013.00194. eCollection 2013.

25.

Natural terpenoids from Ambrosia species are active in vitro and in vivo against human pathogenic trypanosomatids.

Sülsen VP, Cazorla SI, Frank FM, Laurella LC, Muschietti LV, Catalán CA, Martino VS, Malchiodi EL.

PLoS Negl Trop Dis. 2013 Oct 10;7(10):e2494. doi: 10.1371/journal.pntd.0002494. eCollection 2013.

26.

Trypanocidal Activity of Smallanthus sonchifolius: Identification of Active Sesquiterpene Lactones by Bioassay-Guided Fractionation.

Frank FM, Ulloa J, Cazorla SI, Maravilla G, Malchiodi EL, Grau A, Martino V, Catalán C, Muschietti LV.

Evid Based Complement Alternat Med. 2013;2013:627898. doi: 10.1155/2013/627898. Epub 2013 Jun 6.

27.

Plasma membrane calcium ATPase activity is regulated by actin oligomers through direct interaction.

Dalghi MG, Fernández MM, Ferreira-Gomes M, Mangialavori IC, Malchiodi EL, Strehler EE, Rossi JP.

J Biol Chem. 2013 Aug 9;288(32):23380-93. doi: 10.1074/jbc.M113.470542. Epub 2013 Jun 26.

28.

Uptake and intracellular trafficking of superantigens in dendritic cells.

Ganem MB, De Marzi MC, Fernández-Lynch MJ, Jancic C, Vermeulen M, Geffner J, Mariuzza RA, Fernández MM, Malchiodi EL.

PLoS One. 2013 Jun 14;8(6):e66244. doi: 10.1371/journal.pone.0066244. Print 2013.

29.

Trypanosoma cruzi, the causative agent of Chagas disease, modulates interleukin-6-induced STAT3 phosphorylation via gp130 cleavage in different host cells.

Ponce NE, Carrera-Silva EA, Pellegrini AV, Cazorla SI, Malchiodi EL, Lima AP, Gea S, Aoki MP.

Biochim Biophys Acta. 2013 Mar;1832(3):485-94. doi: 10.1016/j.bbadis.2012.12.003. Epub 2012 Dec 16.

30.

Antiparasitic Effect of Vitamin B12 on Trypanosoma cruzi.

Ciccarelli AB, Frank FM, Puente V, Malchiodi EL, Batlle A, Lombardo ME.

Antimicrob Agents Chemother. 2012 Oct;56(10):5315-20. doi: 10.1128/AAC.00481-12. Epub 2012 Aug 6.

31.

Synthesis, trypanocidal activity and molecular modeling studies of 2-alkylaminomethylquinoline derivatives.

Muscia GC, Cazorla SI, Frank FM, Borosky GL, Buldain GY, Asís SE, Malchiodi EL.

Eur J Med Chem. 2011 Sep;46(9):3696-703. doi: 10.1016/j.ejmech.2011.05.035. Epub 2011 May 20.

PMID:
21664012
32.

Psilostachyin C: a natural compound with trypanocidal activity.

Sülsen VP, Frank FM, Cazorla SI, Barrera P, Freixa B, Vila R, Sosa MA, Malchiodi EL, Muschietti LV, Martino VS.

Int J Antimicrob Agents. 2011 Jun;37(6):536-43. doi: 10.1016/j.ijantimicag.2011.02.003. Epub 2011 Apr 15.

PMID:
21497061
33.

Crystal structure of staphylococcal enterotoxin G (SEG) in complex with a mouse T-cell receptor {beta} chain.

Fernández MM, Cho S, De Marzi MC, Kerzic MC, Robinson H, Mariuzza RA, Malchiodi EL.

J Biol Chem. 2011 Jan 14;286(2):1189-95. doi: 10.1074/jbc.M110.142471. Epub 2010 Nov 8.

34.

Differential effects of paromomycin on ribosomes of Leishmania mexicana and mammalian cells.

Fernández MM, Malchiodi EL, Algranati ID.

Antimicrob Agents Chemother. 2011 Jan;55(1):86-93. doi: 10.1128/AAC.00506-10. Epub 2010 Oct 18.

35.

Modulation of endothelial cell migration and angiogenesis: a novel function for the "tandem-repeat" lectin galectin-8.

Delgado VM, Nugnes LG, Colombo LL, Troncoso MF, Fernández MM, Malchiodi EL, Frahm I, Croci DO, Compagno D, Rabinovich GA, Wolfenstein-Todel C, Elola MT.

FASEB J. 2011 Jan;25(1):242-54. doi: 10.1096/fj.09-144907. Epub 2010 Sep 27.

PMID:
20876211
36.

Redirection of the immune response to the functional catalytic domain of the cystein proteinase cruzipain improves protective immunity against Trypanosoma cruzi infection.

Cazorla SI, Frank FM, Becker PD, Arnaiz M, Mirkin GA, Corral RS, Guzmán CA, Malchiodi EL.

J Infect Dis. 2010 Jul 1;202(1):136-44. doi: 10.1086/652872.

PMID:
20497050
37.

Inhibition of HIV-1 replication in human monocyte-derived macrophages by parasite Trypanosoma cruzi.

Andreani G, Celentano AM, Solana ME, Cazorla SI, Malchiodi EL, Martínez Peralta LA, Dolcini GL.

PLoS One. 2009 Dec 14;4(12):e8246. doi: 10.1371/journal.pone.0008246.

38.

Distinct conformations of Ly49 natural killer cell receptors mediate MHC class I recognition in trans and cis.

Back J, Malchiodi EL, Cho S, Scarpellino L, Schneider P, Kerzic MC, Mariuzza RA, Held W.

Immunity. 2009 Oct 16;31(4):598-608. doi: 10.1016/j.immuni.2009.07.007. Epub 2009 Oct 8.

39.

Vaccination approaches against Trypanosoma cruzi infection.

Cazorla SI, Frank FM, Malchiodi EL.

Expert Rev Vaccines. 2009 Jul;8(7):921-35. doi: 10.1586/erv.09.45. Review.

PMID:
19538117
40.

Cellular clot formation in a sipunculan worm: entrapment of foreign particles, cell death and identification of a PGRP-related protein.

Blanco GA, Malchiodi EL, De Marzi MC.

J Invertebr Pathol. 2008 Oct;99(2):156-65. doi: 10.1016/j.jip.2008.05.006. Epub 2008 Jul 14.

PMID:
18621387
41.

Antibody detection employing sol-gel immobilized parasites.

Copello GJ, De Marzi MC, Desimone MF, Malchiodi EL, Díaz LE.

J Immunol Methods. 2008 Jun 1;335(1-2):65-70. doi: 10.1016/j.jim.2008.02.020. Epub 2008 Mar 27.

PMID:
18448116
42.

Trypanocidal and leishmanicidal activities of sesquiterpene lactones from Ambrosia tenuifolia Sprengel (Asteraceae).

Sülsen VP, Frank FM, Cazorla SI, Anesini CA, Malchiodi EL, Freixa B, Vila R, Muschietti LV, Martino VS.

Antimicrob Agents Chemother. 2008 Jul;52(7):2415-9. doi: 10.1128/AAC.01630-07. Epub 2008 Apr 28.

43.

Molecular architecture of the major histocompatibility complex class I-binding site of Ly49 natural killer cell receptors.

Deng L, Cho S, Malchiodi EL, Kerzic MC, Dam J, Mariuzza RA.

J Biol Chem. 2008 Jun 13;283(24):16840-9. doi: 10.1074/jbc.M801526200. Epub 2008 Apr 21.

44.

Prime-boost immunization with cruzipain co-administered with MALP-2 triggers a protective immune response able to decrease parasite burden and tissue injury in an experimental Trypanosoma cruzi infection model.

Cazorla SI, Frank FM, Becker PD, Corral RS, Guzmán CA, Malchiodi EL.

Vaccine. 2008 Apr 7;26(16):1999-2009. doi: 10.1016/j.vaccine.2008.02.011. Epub 2008 Feb 22.

PMID:
18342408
45.

Trypanocidal and leishmanicidal activities of flavonoids from Argentine medicinal plants.

Sülsen VP, Cazorla SI, Frank FM, Redko FC, Anesini CA, Coussio JD, Malchiodi EL, Martino VS, Muschietti LV.

Am J Trop Med Hyg. 2007 Oct;77(4):654-9.

PMID:
17978066
46.

Oral vaccination with Salmonella enterica as a cruzipain-DNA delivery system confers protective immunity against Trypanosoma cruzi.

Cazorla SI, Becker PD, Frank FM, Ebensen T, Sartori MJ, Corral RS, Malchiodi EL, Guzmán CA.

Infect Immun. 2008 Jan;76(1):324-33. Epub 2007 Oct 29.

47.

Superantigen natural affinity maturation revealed by the crystal structure of staphylococcal enterotoxin G and its binding to T-cell receptor Vbeta8.2.

Fernández MM, Bhattacharya S, De Marzi MC, Brown PH, Kerzic M, Schuck P, Mariuzza RA, Malchiodi EL.

Proteins. 2007 Jul 1;68(1):389-402.

PMID:
17427250
48.

Rabbit IgG antibodies against phospholipase A2 from Crotalus durissus terrificus neutralize the lethal activity of the venom.

Rodriguez JP, De Marzi M, Maruñak S, Malchiodi EL, Leiva LC, Acosta O.

Medicina (B Aires). 2006;66(6):512-6.

PMID:
17240621
49.

Variable dimerization of the Ly49A natural killer cell receptor results in differential engagement of its MHC class I ligand.

Dam J, Baber J, Grishaev A, Malchiodi EL, Schuck P, Bax A, Mariuzza RA.

J Mol Biol. 2006 Sep 8;362(1):102-13. Epub 2006 Aug 8.

PMID:
16899255
50.

Crystal structure of staphylococcal enterotoxin I (SEI) in complex with a human major histocompatibility complex class II molecule.

Fernández MM, Guan R, Swaminathan CP, Malchiodi EL, Mariuzza RA.

J Biol Chem. 2006 Sep 1;281(35):25356-64. Epub 2006 Jul 6.

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