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Prospective phase II study of prophylactic low-dose azacitidine and donor lymphocyte infusions following allogeneic hematopoietic stem cell transplantation for high-risk acute myeloid leukemia and myelodysplastic syndrome.

Guillaume T, Malard F, Magro L, Labopin M, Tabrizi R, Borel C, Chevallier P, Vigouroux S, Peterlin P, Garnier A, Rubio MT, Huynh A, Milpied N, Moreau P, Gaugler B, Yakoub-Agha I, Mohty M.

Bone Marrow Transplant. 2019 May 14. doi: 10.1038/s41409-019-0536-y. [Epub ahead of print]


Current status of autologous stem cell transplantation for multiple myeloma.

Al Hamed R, Bazarbachi AH, Malard F, Harousseau JL, Mohty M.

Blood Cancer J. 2019 Apr 8;9(4):44. doi: 10.1038/s41408-019-0205-9. Review.


Impact of cyclosporine A concentration on acute graft-vs-host disease incidence after haploidentical hematopoietic cell transplantation.

Stocker N, Duléry R, Battipaglia G, Brissot E, Médiavilla C, Sestili S, Paviglianiti A, Ledraa T, Mohty R, Bazarbachi A, Belhocine R, Vekhoff A, Ruggeri A, Mohty M, Malard F.

Eur J Haematol. 2019 Jul;103(1):10-17. doi: 10.1111/ejh.13233. Epub 2019 May 14.


IL-7 receptor influences anti-TNF responsiveness and T cell gut homing in inflammatory bowel disease.

Belarif L, Danger R, Kermarrec L, Nerrière-Daguin V, Pengam S, Durand T, Mary C, Kerdreux E, Gauttier V, Kucik A, Thepenier V, Martin JC, Chang C, Rahman A, Guen NS, Braudeau C, Abidi A, David G, Malard F, Takoudju C, Martinet B, Gérard N, Neveu I, Neunlist M, Coron E, MacDonald TT, Desreumaux P, Mai HL, Le Bas-Bernardet S, Mosnier JF, Merad M, Josien R, Brouard S, Soulillou JP, Blancho G, Bourreille A, Naveilhan P, Vanhove B, Poirier N.

J Clin Invest. 2019 Apr 2;129(5):1910-1925. doi: 10.1172/JCI121668. eCollection 2019 Apr 2.


Thiotepa, Busulfan, and Fludarabine Conditioning Regimen in T Cell-Replete HLA-Haploidentical Hematopoietic Stem Cell Transplantation.

Duléry R, Bastos J, Paviglianiti A, Malard F, Brissot E, Battipaglia G, Médiavilla C, Giannotti F, Banet A, de Wyngaert ZV, Ledraa T, Belhocine R, Sestili S, Adaeva R, Lapusan S, Isnard F, Legrand O, Vekhoff A, Rubio MT, Ruggeri A, Mohty M.

Biol Blood Marrow Transplant. 2019 Jul;25(7):1407-1415. doi: 10.1016/j.bbmt.2019.02.025. Epub 2019 Mar 11.


Circulating follicular helper T cells are increased in systemic sclerosis and promote plasmablast differentiation through the IL-21 pathway which can be inhibited by ruxolitinib.

Ricard L, Jachiet V, Malard F, Ye Y, Stocker N, Rivière S, Senet P, Monfort JB, Fain O, Mohty M, Gaugler B, Mekinian A.

Ann Rheum Dis. 2019 Apr;78(4):539-550. doi: 10.1136/annrheumdis-2018-214382. Epub 2019 Feb 13.


Fecal microbiota transplantation before or after allogeneic hematopoietic transplantation in patients with hematologic malignancies carrying multidrug-resistance bacteria.

Battipaglia G, Malard F, Rubio MT, Ruggeri A, Mamez AC, Brissot E, Giannotti F, Dulery R, Joly AC, Baylatry MT, Kossmann MJ, Tankovic J, Beaugerie L, Sokol H, Mohty M.

Haematologica. 2019 Aug;104(8):1682-1688. doi: 10.3324/haematol.2018.198549. Epub 2019 Feb 7.


Erratum: Life History Traits Impact the Nuclear Rate of Substitution but Not the Mitochondrial Rate in Isopods.

Saclier N, François CM, Konecny-Dupré L, Lartillot N, Guéguen L, Duret L, Malard F, Douady CJ, Lefébure T.

Mol Biol Evol. 2019 Mar 1;36(3):641. doi: 10.1093/molbev/msy247. No abstract available.


Rhino-orbital Mucormycosis presenting as facial cellulitis in a patient with high-risk acute myeloid leukemia in relapse.

Debureaux PE, Paccoud O, Guitard J, Baujat B, Ruggeri A, Battipaglia G, Duléry R, Giannotti F, Malard F, Mohty M, Brissot E.

Curr Res Transl Med. 2019 May;67(2):76-78. doi: 10.1016/j.retram.2019.01.004. Epub 2019 Jan 25. No abstract available.


CD34+-selected stem cell "Boost" for poor graft function after allogeneic hematopoietic stem cell transplantation.

Mohty R, Brissot E, Battipaglia G, Ruggeri A, Sestili S, Mediavilla C, Belhocine R, Dulery R, Mohty M, Malard F.

Curr Res Transl Med. 2019 Aug;67(3):112-114. doi: 10.1016/j.retram.2018.12.003. Epub 2018 Dec 25. No abstract available.


Cutaneous lupus with Kikuchi disease-like inflammatory pattern associated with myelodysplastic syndrome.

Delplanque M, Chasset F, Hirsch P, Malard F, Ditchi Y, Fain O, Mekinian A.

Rheumatology (Oxford). 2019 Mar 1;58(3):554-556. doi: 10.1093/rheumatology/key413. No abstract available.


[Second allogeneic hematopoietic stem cell transplant: Guidelines from the francophone Society of bone marrow transplantation and cellular therapy (SFGM-TC)].

Yafour N, Couturier MA, Azarnoush S, Girault S, Hermet E, Masouridi Levrat S, Schmidt A, Michallet M, Etancelin P, Guillaume T, Malard F, Sirvent A, Yakoub-Agha I, Poiré X.

Bull Cancer. 2019 Jan;106(1S):S40-S51. doi: 10.1016/j.bulcan.2018.05.018. Epub 2018 Nov 6. Review. French.


Ex vivo and in vivo T cell-depleted allogeneic stem cell transplantation in patients with acute myeloid leukemia in first complete remission resulted in similar overall survival: on behalf of the ALWP of the EBMT and the MSKCC.

Malard F, Labopin M, Cho C, Blaise D, Papadopoulos EB, Passweg J, O'Reilly R, Forcade E, Maloy M, Volin L, Castro-Malaspina H, Hicheri Y, Jakubowski AA, Orvain C, Giralt S, Mohty M, Nagler A, Perales MA.

J Hematol Oncol. 2018 Oct 20;11(1):127. doi: 10.1186/s13045-018-0668-3.


Life History Traits Impact the Nuclear Rate of Substitution but Not the Mitochondrial Rate in Isopods.

Saclier N, François CM, Konecny-Dupré L, Lartillot N, Guéguen L, Duret L, Malard F, Douady CJ, Lefébure T.

Mol Biol Evol. 2018 Dec 1;35(12):2900-2912. doi: 10.1093/molbev/msy184. Erratum in: Mol Biol Evol. 2019 Mar 1;36(3):641.


High gastrointestinal microbial diversity and clinical outcome in graft-versus-host disease patients.

Malard F, Gasc C, Plantamura E, Doré J.

Bone Marrow Transplant. 2018 Dec;53(12):1493-1497. doi: 10.1038/s41409-018-0254-x. Epub 2018 Jun 14. Review. No abstract available.


Quantitative and functional alterations of 6-sulfo LacNac dendritic cells in multiple myeloma.

Lamarthée B, de Vassoigne F, Malard F, Stocker N, Boussen I, Médiavilla C, Tang R, Fava F, Garderet L, Marjanovic Z, Brissot E, Mohty M, Gaugler B.

Oncoimmunology. 2018 Mar 19;7(7):e1444411. doi: 10.1080/2162402X.2018.1444411. eCollection 2018.


Prevention and treatment of relapse after stem cell transplantation by cellular therapies.

Falkenburg F, Ruggiero E, Bonini C, Porter D, Miller J, Malard F, Mohty M, Kröger N, Kolb HJ.

Bone Marrow Transplant. 2019 Jan;54(1):26-34. doi: 10.1038/s41409-018-0227-0. Epub 2018 May 24.


Conformational Ensemble and Biological Role of the TCTP Intrinsically Disordered Region: Influence of Calcium and Phosphorylation.

Malard F, Assrir N, Alami M, Messaoudi S, Lescop E, Ha-Duong T.

J Mol Biol. 2018 May 25;430(11):1621-1639. doi: 10.1016/j.jmb.2018.04.024. Epub 2018 Apr 30.


Defibrotide for Sinusoidal Obstruction Syndrome/Veno-Occlusive Disease Prophylaxis in High-Risk Adult Patients: A Single-Center Experience Study.

Picod A, Bonnin A, Battipaglia G, Giannotti F, Ruggeri A, Brissot E, Malard F, Médiavilla C, Belhocine R, Vekhoff A, Gueye MS, Lapusan S, Adaeva R, Isnard F, Legrand O, Baylatry MT, Joly AC, Labopin M, Duléry R, Mohty M.

Biol Blood Marrow Transplant. 2018 Jul;24(7):1471-1475. doi: 10.1016/j.bbmt.2018.02.015. Epub 2018 Mar 1.


Reply to J.J. Boelens et al.

Mohty M, Malard F.

J Clin Oncol. 2018 Apr 10;36(11):1177-1178. doi: 10.1200/JCO.2017.77.2947. Epub 2018 Feb 7. No abstract available.


Biomarkers in chronic graft-versus-host disease: quo vadis?

Wolff D, Greinix H, Lee SJ, Gooley T, Paczesny S, Pavletic S, Hakim F, Malard F, Jagasia M, Lawitschka A, Hansen JA, Pulanic D, Holler E, Dickinson A, Weissinger E, Edinger M, Sarantopoulos S, Schultz KR.

Bone Marrow Transplant. 2018 Jul;53(7):832-837. doi: 10.1038/s41409-018-0092-x. Epub 2018 Jan 24.


Sequential Conditioning with Thiotepa in T Cell- Replete Hematopoietic Stem Cell Transplantation for the Treatment of Refractory Hematologic Malignancies: Comparison with Matched Related, Haplo-Mismatched, and Unrelated Donors.

Duléry R, Ménard AL, Chantepie S, El-Cheikh J, François S, Delage J, Giannotti F, Ruggeri A, Brissot E, Battipaglia G, Malard F, Belhocine R, Sestili S, Vekhoff A, Delhommeau F, Reman O, Legrand O, Labopin M, Rubio MT, Mohty M.

Biol Blood Marrow Transplant. 2018 May;24(5):1013-1021. doi: 10.1016/j.bbmt.2018.01.005. Epub 2018 Jan 11.


Cryptic species as a window into the paradigm shift of the species concept.

Fišer C, Robinson CT, Malard F.

Mol Ecol. 2018 Feb;27(3):613-635. doi: 10.1111/mec.14486. Epub 2018 Feb 16. Review.


Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration.

Wertheimer T, Velardi E, Tsai J, Cooper K, Xiao S, Kloss CC, Ottmüller KJ, Mokhtari Z, Brede C, deRoos P, Kinsella S, Palikuqi B, Ginsberg M, Young LF, Kreines F, Lieberman SR, Lazrak A, Guo P, Malard F, Smith OM, Shono Y, Jenq RR, Hanash AM, Nolan DJ, Butler JM, Beilhack A, Manley NR, Rafii S, Dudakov JA, van den Brink MRM.

Sci Immunol. 2018 Jan 12;3(19). pii: eaal2736. doi: 10.1126/sciimmunol.aal2736.


Structural Insights into TCTP and Its Interactions with Ligands and Proteins.

Assrir N, Malard F, Lescop E.

Results Probl Cell Differ. 2017;64:9-46. doi: 10.1007/978-3-319-67591-6_2. Review.


Antithymocyte Globulin for Graft-Versus-Host Disease Prophylaxis After Allogeneic Hematopoietic Stem-Cell Transplantation.

Mohty M, Malard F.

J Clin Oncol. 2017 Dec 20;35(36):3993-3995. doi: 10.1200/JCO.2017.76.0512. Epub 2017 Oct 31. No abstract available.


Rituximab-based first-line treatment of cGVHD after allogeneic SCT: results of a phase 2 study.

Malard F, Labopin M, Yakoub-Agha I, Chantepie S, Guillaume T, Blaise D, Tabrizi R, Magro L, Vanhove B, Blancho G, Moreau P, Gaugler B, Chevallier P, Mohty M.

Blood. 2017 Nov 16;130(20):2186-2195. doi: 10.1182/blood-2017-05-786137. Epub 2017 Sep 1.


Less effective selection leads to larger genomes.

Lefébure T, Morvan C, Malard F, François C, Konecny-Dupré L, Guéguen L, Weiss-Gayet M, Seguin-Orlando A, Ermini L, Sarkissian C, Charrier NP, Eme D, Mermillod-Blondin F, Duret L, Vieira C, Orlando L, Douady CJ.

Genome Res. 2017 Jun;27(6):1016-1028. doi: 10.1101/gr.212589.116. Epub 2017 Apr 19.


Posttransplant maintenance therapy in multiple myeloma: the changing landscape.

Sengsayadeth S, Malard F, Savani BN, Garderet L, Mohty M.

Blood Cancer J. 2017 Mar 24;7(3):e545. doi: 10.1038/bcj.2017.23. Review.


Interferon-Alpha Promotes Th1 Response and Epithelial Apoptosis via Inflammasome Activation in Human Intestinal Mucosa.

Jarry A, Malard F, Bou-Hanna C, Meurette G, Mohty M, Mosnier JF, Laboisse CL, Bossard C.

Cell Mol Gastroenterol Hepatol. 2016 Sep 20;3(1):72-81. doi: 10.1016/j.jcmgh.2016.09.007. eCollection 2017 Jan.


Immune Reconstitution after Allogeneic Hematopoietic Stem Cell Transplantation: Time To T Up the Thymus.

Chaudhry MS, Velardi E, Malard F, van den Brink MR.

J Immunol. 2017 Jan 1;198(1):40-46. Review.


Multiple myeloma treatment at relapse after autologous stem cell transplantation: A practical analysis.

Malard F, Harousseau JL, Mohty M.

Cancer Treat Rev. 2017 Jan;52:41-47. doi: 10.1016/j.ctrv.2016.11.005. Epub 2016 Nov 15. Review.


Sequential Intensified Conditioning Regimen Allogeneic Hematopoietic Stem Cell Transplantation in Adult Patients with Intermediate- or High-Risk Acute Myeloid Leukemia in Complete Remission: A Study from the Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation.

Malard F, Labopin M, Stuhler G, Bittenbring J, Ganser A, Tischer J, Michallet M, Kröger N, Schmid C, Huynh A, Hallek M, Savani BN, Mohty M, Nagler A.

Biol Blood Marrow Transplant. 2017 Feb;23(2):278-284. doi: 10.1016/j.bbmt.2016.11.002. Epub 2016 Nov 2.


Impact of KIR/HLA genetic combinations on double umbilical cord blood transplantation outcomes. Results of a French multicentric retrospective study on behalf of the Société Francophone de Greffe de Moelle et de Thérapie Cellulaire (SFGM-TC) and the Société Francophone d'Histocompatibilité et d'Immunogénétique (SFHI).

Rettman P, Malard F, Legrand N, Avinens O, Eliaou JF, Picard C, Dormoy A, Lafarge X, de Matteis M, Kennel A, Loiseau P, Devys A, Boudifa A, Absi L, Fort M, Masson D, Quainon F, Theodorou I, Batho A, Parissiadis A, Delbos F, Drouet M, Senitzer D, Marry E, Raus N, Yakoub-Agha I, Cesbron A, Retière C, Gagne K.

Bone Marrow Transplant. 2016 Nov;51(11):1499-1503. doi: 10.1038/bmt.2016.151. Epub 2016 Jun 6. No abstract available.


Post-transplant cyclophosphamide versus anti-thymocyte globulin as graft- versus-host disease prophylaxis in haploidentical transplant.

Ruggeri A, Sun Y, Labopin M, Bacigalupo A, Lorentino F, Arcese W, Santarone S, Gülbas Z, Blaise D, Messina G, Ghavamzadeh A, Malard F, Bruno B, Diez-Martin JL, Koc Y, Ciceri F, Mohty M, Nagler A.

Haematologica. 2017 Feb;102(2):401-410. doi: 10.3324/haematol.2016.151779. Epub 2016 Oct 6.


Late Complications and Quality of Life after Reduced-Intensity Conditioning Allogeneic Stem Cell Transplantation.

Clavert A, Peric Z, Brissot E, Malard F, Guillaume T, Delaunay J, Dubruille V, Le Gouill S, Mahe B, Gastinne T, Blin N, Harousseau JL, Moreau P, Milpied N, Mohty M, Chevallier P.

Biol Blood Marrow Transplant. 2017 Jan;23(1):140-146. doi: 10.1016/j.bbmt.2016.10.011. Epub 2016 Oct 14.


Sequential regimen of clofarabine, cytosine arabinoside and reduced-intensity conditioned transplantation for primary refractory acute myeloid leukemia.

Mohty M, Malard F, Blaise D, Milpied N, Socié G, Huynh A, Reman O, Yakoub-Agha I, Furst S, Guillaume T, Tabrizi R, Vigouroux S, Peterlin P, El-Cheikh J, Moreau P, Labopin M, Chevallier P.

Haematologica. 2017 Jan;102(1):184-191. doi: 10.3324/haematol.2016.150326. Epub 2016 Aug 25.


No Evidence That Nitrogen Limitation Influences the Elemental Composition of Isopod Transcriptomes and Proteomes.

Francois CM, Duret L, Simon L, Mermillod-Blondin F, Malard F, Konecny-Dupré L, Planel R, Penel S, Douady CJ, Lefébure T.

Mol Biol Evol. 2016 Oct;33(10):2605-20. doi: 10.1093/molbev/msw131. Epub 2016 Jul 8.


Revised diagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a new classification from the European Society for Blood and Marrow Transplantation.

Mohty M, Malard F, Abecassis M, Aerts E, Alaskar AS, Aljurf M, Arat M, Bader P, Baron F, Bazarbachi A, Blaise D, Ciceri F, Corbacioglu S, Dalle JH, Dignan F, Fukuda T, Huynh A, Masszi T, Michallet M, Nagler A, NiChonghaile M, Okamoto S, Pagliuca A, Peters C, Petersen FB, Richardson PG, Ruutu T, Savani BN, Wallhult E, Yakoub-Agha I, Duarte RF, Carreras E.

Bone Marrow Transplant. 2016 Jul;51(7):906-12. doi: 10.1038/bmt.2016.130. Epub 2016 May 16.


Interleukin-22 in Graft-Versus-Host Disease after Allogeneic Stem Cell Transplantation.

Lamarthée B, Malard F, Saas P, Mohty M, Gaugler B.

Front Immunol. 2016 Apr 19;7:148. doi: 10.3389/fimmu.2016.00148. eCollection 2016. Review.


Larger number of invariant natural killer T cells in PBSC allografts correlates with improved GVHD-free and progression-free survival.

Malard F, Labopin M, Chevallier P, Guillaume T, Duquesne A, Rialland F, Derenne S, Peterlin P, Leauté AG, Brissot E, Gregoire M, Moreau P, Saas P, Gaugler B, Mohty M.

Blood. 2016 Apr 7;127(14):1828-35. doi: 10.1182/blood-2015-12-688739. Epub 2016 Feb 22. Erratum in: Blood. 2018 Oct 18;132(16):1726.


Translational opportunities for targeting the Th17 axis in acute graft-vs.-host disease.

Malard F, Gaugler B, Lamarthee B, Mohty M.

Mucosal Immunol. 2016 Mar;9(2):299-308. doi: 10.1038/mi.2015.143. Epub 2016 Jan 27. Review.


Impact of pre-transplant diffusion lung capacity for nitric oxide (DLNO) and of DLNO/pre-transplant diffusion lung capacity for carbon monoxide (DLNO/DLCO) ratio on pulmonary outcomes in adults receiving allogeneic stem cell transplantation for hematological diseases.

Le Bourgeois A, Malard F, Chevallier P, Urbistandoy G, Guillaume T, Delaunay J, Peterlin P, Lemarchand P, Germaud P, Mohty M, Moreau P, Chambellan A.

Bone Marrow Transplant. 2016 Apr;51(4):589-92. doi: 10.1038/bmt.2015.284. Epub 2015 Nov 23. No abstract available.


Monosomal karyotype as an adverse prognostic factor in patients with acute myeloid leukemia treated with allogeneic hematopoietic stem-cell transplantation in first complete remission: a retrospective survey on behalf of the ALWP of the EBMT.

Brands-Nijenhuis AV, Labopin M, Schouten HC, Volin L, Socié G, Cornelissen JJ, Huynh A, Ljungman P, Malard F, Esteve J, Nagler A, Mohty M.

Haematologica. 2016 Feb;101(2):248-55. doi: 10.3324/haematol.2015.132654. Epub 2015 Nov 20.


Allogeneic hematopoietic cell transplantation in acute myeloid leukemia with normal karyotype and isolated Nucleophosmin-1 (NPM1) mutation: outcome strongly correlates with disease status.

Bazarbachi A, Labopin M, Kharfan-Dabaja MA, Schwerdtfeger R, Volin L, Bourhis JH, Socié G, Daguindau E, Gedde-Dahl T, Rambaldi A, Karas M, Schlimok G, Blaise D, Chevallier P, Malard F, Schmid C, Esteve J, Nagler A, Mohty M.

Haematologica. 2016 Jan;101(1):e34-7. doi: 10.3324/haematol.2015.135681. Epub 2015 Sep 24. No abstract available.


Incidence and risk factors for hemorrhagic cystitis in unmanipulated haploidentical transplant recipients.

Ruggeri A, Roth-Guepin G, Battipaglia G, Mamez AC, Malard F, Gomez A, Brissot E, Belhocine R, Vekhoff A, Lapusan S, Isnard F, Legrand O, Gozlan J, Boutolleau D, Ledraa T, Labopin M, Rubio MT, Mohty M.

Transpl Infect Dis. 2015 Dec;17(6):822-30. doi: 10.1111/tid.12455. Epub 2015 Nov 25.


Safety and feasibility of romiplostim treatment for patients with persistent thrombocytopenia after allogeneic stem cell transplantation.

Battipaglia G, Ruggeri A, Brissot E, Mamez AC, Malard F, Belhocine R, Vekhoff A, Giannotti F, Ledraa T, Labopin M, Rubio MT, Mohty M.

Bone Marrow Transplant. 2015 Dec;50(12):1574-7. doi: 10.1038/bmt.2015.182. Epub 2015 Aug 17. No abstract available.


Donor interleukin-22 and host type I interferon signaling pathway participate in intestinal graft-versus-host disease via STAT1 activation and CXCL10.

Lamarthée B, Malard F, Gamonet C, Bossard C, Couturier M, Renauld JC, Mohty M, Saas P, Gaugler B.

Mucosal Immunol. 2016 Mar;9(2):309-21. doi: 10.1038/mi.2015.61. Epub 2015 Jul 8.


Reduced intensity conditioning allogeneic hematopoietic cell transplantation for adult acute myeloid leukemia in complete remission - a review from the Acute Leukemia Working Party of the EBMT.

Sengsayadeth S, Savani BN, Blaise D, Malard F, Nagler A, Mohty M.

Haematologica. 2015 Jul;100(7):859-69. doi: 10.3324/haematol.2015.123331. Review.


Outcome of allogeneic hematopoietic stem-cell transplantation for adult patients with AML and 11q23/MLL rearrangement (MLL-r AML).

Pigneux A, Labopin M, Maertens J, Cordonnier C, Volin L, Socié G, Blaise D, Craddock C, Milpied N, Bacher U, Malard F, Esteve J, Nagler A, Mohty M; Acute Leukemia Working Party EBMT.

Leukemia. 2015 Dec;29(12):2375-81. doi: 10.1038/leu.2015.143. Epub 2015 Jun 17.


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