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Items: 35

1.

Identification of mesothelial cells in intraoperative blood salvage.

Santise G, Maselli D, Malanga D, Di Vito A, Mandarino N, Boccadamo G, Zeppa P, Amorosi A, Viglietto G, Rizzuto A, Mignogna C.

Am J Transl Res. 2019 Mar 15;11(3):1771-1779. eCollection 2019.

2.

Inhibition of histone methyltransferase DOT1L silences ERα gene and blocks proliferation of antiestrogen-resistant breast cancer cells.

Nassa G, Salvati A, Tarallo R, Gigantino V, Alexandrova E, Memoli D, Sellitto A, Rizzo F, Malanga D, Mirante T, Morelli E, Nees M, Åkerfelt M, Kangaspeska S, Nyman TA, Milanesi L, Giurato G, Weisz A.

Sci Adv. 2019 Feb 6;5(2):eaav5590. doi: 10.1126/sciadv.aav5590. eCollection 2019 Feb.

3.

The T197A Knock-in Model of Cdkn1b Gene to Study the Effects of p27 Restoration In Vivo.

De Marco C, Rinaldo N, De Vita F, Forzati F, Caira E, Iovane V, Paciello O, Montanaro D, D'Andrea S, Baldassarre G, Papparella S, Malanga D, Baldi A, Viglietto G.

Mol Cancer Ther. 2019 Feb;18(2):482-493. doi: 10.1158/1535-7163.MCT-18-0134. Epub 2018 Nov 13.

PMID:
30425132
4.

Correction to: Next-generation sequencing analysis of receptor-type tyrosine kinase genes in surgically resected colon cancer: identification of gain-of-function mutations in the RET proto-oncogene.

Oliveira DM, Grillone K, Mignogna C, De Falco V, Laudanna C, Biamonte F, Locane R, Corcione F, Fabozzi M, Sacco R, Viglietto G, Malanga D, Rizzuto A.

J Exp Clin Cancer Res. 2018 Jun 1;37(1):112. doi: 10.1186/s13046-018-0776-5.

5.

Simultaneous identification of clinically relevant single nucleotide variants, copy number alterations and gene fusions in solid tumors by targeted next-generation sequencing.

Oliveira DM, Mirante T, Mignogna C, Scrima M, Migliozzi S, Rocco G, Franco R, Corcione F, Viglietto G, Malanga D, Rizzuto A.

Oncotarget. 2018 Apr 27;9(32):22749-22768. doi: 10.18632/oncotarget.25229. eCollection 2018 Apr 27.

6.

Identification of different mutational profiles in cancers arising in specific colon segments by next generation sequencing.

Oliveira DM, Laudanna C, Migliozzi S, Zoppoli P, Santamaria G, Grillone K, Elia L, Mignogna C, Biamonte F, Sacco R, Corcione F, Viglietto G, Malanga D, Rizzuto A.

Oncotarget. 2018 May 8;9(35):23960-23974. doi: 10.18632/oncotarget.25251. eCollection 2018 May 8.

7.

Centrosome Linker-induced Tetraploid Segregation Errors Link Rhabdoid Phenotypes and Lethal Colorectal Cancers.

Remo A, Manfrin E, Parcesepe P, Ferrarini A, Han HS, Mickys U, Laudanna C, Simbolo M, Malanga D, Oliveira DM, Baritono E, Colangelo T, Sabatino L, Giuliani J, Molinari E, Garonzi M, Xumerle L, Delledonne M, Giordano G, Ghimenton C, Lonardo F, D'angelo F, Grillo F, Mastracci L, Viglietto G, Ceccarelli M, Colantuoni V, Scarpa A, Pancione M.

Mol Cancer Res. 2018 Sep;16(9):1385-1395. doi: 10.1158/1541-7786.MCR-18-0062. Epub 2018 May 21.

8.

Identification of copy number alterations in colon cancer from analysis of amplicon-based next generation sequencing data.

Oliveira DM, Santamaria G, Laudanna C, Migliozzi S, Zoppoli P, Quist M, Grasso C, Mignogna C, Elia L, Faniello MC, Marinaro C, Sacco R, Corcione F, Viglietto G, Malanga D, Rizzuto A.

Oncotarget. 2018 Apr 17;9(29):20409-20425. doi: 10.18632/oncotarget.24912. eCollection 2018 Apr 17.

9.

Next-generation sequencing analysis of receptor-type tyrosine kinase genes in surgically resected colon cancer: identification of gain-of-function mutations in the RET proto-oncogene.

Mendes Oliveira D, Grillone K, Mignogna C, De Falco V, Laudanna C, Biamonte F, Locane R, Corcione F, Fabozzi M, Sacco R, Viglietto G, Malanga D, Rizzuto A.

J Exp Clin Cancer Res. 2018 Apr 17;37(1):84. doi: 10.1186/s13046-018-0746-y. Erratum in: J Exp Clin Cancer Res. 2018 Jun 1;37(1):112.

10.

Ferritin Heavy Subunit Silencing Blocks the Erythroid Commitment of K562 Cells via miR-150 up-Regulation and GATA-1 Repression.

Zolea F, Battaglia AM, Chiarella E, Malanga D, De Marco C, Bond HM, Morrone G, Costanzo F, Biamonte F.

Int J Mol Sci. 2017 Oct 17;18(10). pii: E2167. doi: 10.3390/ijms18102167.

11.

Epithelial-to-mesenchymal transition in FHC-silenced cells: the role of CXCR4/CXCL12 axis.

Aversa I, Zolea F, Ieranò C, Bulotta S, Trotta AM, Faniello MC, De Marco C, Malanga D, Biamonte F, Viglietto G, Cuda G, Scala S, Costanzo F.

J Exp Clin Cancer Res. 2017 Aug 3;36(1):104. doi: 10.1186/s13046-017-0571-8.

12.

Specific gene expression signatures induced by the multiple oncogenic alterations that occur within the PTEN/PI3K/AKT pathway in lung cancer.

De Marco C, Laudanna C, Rinaldo N, Oliveira DM, Ravo M, Weisz A, Ceccarelli M, Caira E, Rizzuto A, Zoppoli P, Malanga D, Viglietto G.

PLoS One. 2017 Jun 29;12(6):e0178865. doi: 10.1371/journal.pone.0178865. eCollection 2017.

13.

Aberrant Signaling through the HER2-ERK1/2 Pathway is Predictive of Reduced Disease-Free and Overall Survival in Early Stage Non-Small Cell Lung Cancer (NSCLC) Patients.

Scrima M, Zito Marino F, Oliveira DM, Marinaro C, La Mantia E, Rocco G, De Marco C, Malanga D, De Rosa N, Rizzuto A, Botti G, Franco R, Zoppoli P, Viglietto G.

J Cancer. 2017 Jan 15;8(2):227-239. doi: 10.7150/jca.17093. eCollection 2017.

14.

Analysis of miRNA profiles identified miR-196a as a crucial mediator of aberrant PI3K/AKT signaling in lung cancer cells.

Guerriero I, D'Angelo D, Pallante P, Santos M, Scrima M, Malanga D, De Marco C, Ravo M, Weisz A, Laudanna C, Ceccarelli M, Falco G, Rizzuto A, Viglietto G.

Oncotarget. 2017 Mar 21;8(12):19172-19191. doi: 10.18632/oncotarget.13432.

15.

Detection of Natural Resistance-Associated Substitutions by Ion Semiconductor Technology in HCV1b Positive, Direct-Acting Antiviral Agents-Naïve Patients.

Marascio N, Pavia G, Strazzulla A, Dierckx T, Cuypers L, Vrancken B, Barreca GS, Mirante T, Malanga D, Oliveira DM, Vandamme AM, Torti C, Liberto MC, Focà A; The SINERGIE-UMG Study Group.

Int J Mol Sci. 2016 Aug 27;17(9). pii: E1416. doi: 10.3390/ijms17091416.

16.

Multivisceral resection for occlusive colorectal cancer: Is it justified?

Rizzuto A, Palaia I, Vescio G, Serra R, Malanga D, Sacco R.

Int J Surg. 2016 Sep;33 Suppl 1:S142-7. doi: 10.1016/j.ijsu.2016.06.021. Epub 2016 Jul 8.

17.

AKT1E¹⁷K Is Oncogenic in Mouse Lung and Cooperates with Chemical Carcinogens in Inducing Lung Cancer.

Malanga D, Belmonte S, Colelli F, Scarfò M, De Marco C, Oliveira DM, Mirante T, Camastra C, Gagliardi M, Rizzuto A, Mignogna C, Paciello O, Papparella S, Fagman H, Viglietto G.

PLoS One. 2016 Feb 9;11(2):e0147334. doi: 10.1371/journal.pone.0147334. eCollection 2016.

18.

The Akt1/IL-6/STAT3 pathway regulates growth of lung tumor initiating cells.

Malanga D, De Marco C, Guerriero I, Colelli F, Rinaldo N, Scrima M, Mirante T, De Vitis C, Zoppoli P, Ceccarelli M, Riccardi M, Ravo M, Weisz A, Federico A, Franco R, Rocco G, Mancini R, Rizzuto A, Gulletta E, Ciliberto G, Viglietto G.

Oncotarget. 2015 Dec 15;6(40):42667-86. doi: 10.18632/oncotarget.5626.

19.

Mutant AKT1-E17K is oncogenic in lung epithelial cells.

De Marco C, Malanga D, Rinaldo N, De Vita F, Scrima M, Lovisa S, Fabris L, Carriero MV, Franco R, Rizzuto A, Baldassarre G, Viglietto G.

Oncotarget. 2015 Nov 24;6(37):39634-50. doi: 10.18632/oncotarget.4022.

20.

Co-regulated expression of alpha and beta mRNAs encoding HLA-DR surface heterodimers is mediated by the MHCII RNA operon.

Pisapia L, Cicatiello V, Barba P, Malanga D, Maffei A, Hamilton RS, Del Pozzo G.

Nucleic Acids Res. 2013 Apr 1;41(6):3772-86. doi: 10.1093/nar/gkt059. Epub 2013 Feb 7.

21.

Nonredundant and locus-specific gene repression functions of PRC1 paralog family members in human hematopoietic stem/progenitor cells.

van den Boom V, Rozenveld-Geugien M, Bonardi F, Malanga D, van Gosliga D, Heijink AM, Viglietto G, Morrone G, Fusetti F, Vellenga E, Schuringa JJ.

Blood. 2013 Mar 28;121(13):2452-61. doi: 10.1182/blood-2012-08-451666. Epub 2013 Jan 24.

PMID:
23349393
22.

PKC-dependent phosphorylation of p27 at T198 contributes to p27 stabilization and cell cycle arrest.

De Vita F, Riccardi M, Malanga D, Scrima M, De Marco C, Viglietto G.

Cell Cycle. 2012 Apr 15;11(8):1583-92. doi: 10.4161/cc.20003. Epub 2012 Apr 15.

PMID:
22441823
23.

Signaling networks associated with AKT activation in non-small cell lung cancer (NSCLC): new insights on the role of phosphatydil-inositol-3 kinase.

Scrima M, De Marco C, Fabiani F, Franco R, Pirozzi G, Rocco G, Ravo M, Weisz A, Zoppoli P, Ceccarelli M, Botti G, Malanga D, Viglietto G.

PLoS One. 2012;7(2):e30427. doi: 10.1371/journal.pone.0030427. Epub 2012 Feb 17.

24.

The nonreceptor-type tyrosine phosphatase PTPN13 is a tumor suppressor gene in non-small cell lung cancer.

Scrima M, De Marco C, De Vita F, Fabiani F, Franco R, Pirozzi G, Rocco G, Malanga D, Viglietto G.

Am J Pathol. 2012 Mar;180(3):1202-14. doi: 10.1016/j.ajpath.2011.11.038. Epub 2012 Jan 13.

PMID:
22245727
25.

Functional characterization of a rare germline mutation in the gene encoding the cyclin-dependent kinase inhibitor p27Kip1 (CDKN1B) in a Spanish patient with multiple endocrine neoplasia-like phenotype.

Malanga D, De Gisi S, Riccardi M, Scrima M, De Marco C, Robledo M, Viglietto G.

Eur J Endocrinol. 2012 Mar;166(3):551-60. doi: 10.1530/EJE-11-0929. Epub 2011 Nov 30.

PMID:
22129891
26.

Spheres derived from lung adenocarcinoma pleural effusions: molecular characterization and tumor engraftment.

Mancini R, Giarnieri E, De Vitis C, Malanga D, Roscilli G, Noto A, Marra E, Laudanna C, Zoppoli P, De Luca P, Affuso A, Ruco L, Di Napoli A, Mesiti G, Aurisicchio L, Ricci A, Mariotta S, Pisani L, Andreetti C, Viglietto G, Rendina EA, Giovagnoli MR, Ciliberto G.

PLoS One. 2011;6(7):e21320. doi: 10.1371/journal.pone.0021320. Epub 2011 Jul 18.

27.

Contribution of PKB/AKT signaling to thyroid cancer.

Viglietto G, Amodio N, Malanga D, Scrima M, De Marco C.

Front Biosci (Landmark Ed). 2011 Jan 1;16:1461-87. Review.

PMID:
21196242
28.

Allelic variant at -79 (C>T) in CDKN1B (p27Kip1) confers an increased risk of thyroid cancer and alters mRNA levels.

Landa I, Montero-Conde C, Malanga D, De Gisi S, Pita G, Leandro-García LJ, Inglada-Pérez L, Letón R, De Marco C, Rodríguez-Antona C, Viglietto G, Robledo M.

Endocr Relat Cancer. 2010 Jun 1;17(2):317-28. doi: 10.1677/ERC-09-0016. Print 2010 Jun.

PMID:
20075119
29.

The role of CD133 in the identification and characterisation of tumour-initiating cells in non-small-cell lung cancer.

Tirino V, Camerlingo R, Franco R, Malanga D, La Rocca A, Viglietto G, Rocco G, Pirozzi G.

Eur J Cardiothorac Surg. 2009 Sep;36(3):446-53. doi: 10.1016/j.ejcts.2009.03.063. Epub 2009 May 22.

PMID:
19464919
30.

Activating E17K mutation in the gene encoding the protein kinase AKT1 in a subset of squamous cell carcinoma of the lung.

Malanga D, Scrima M, De Marco C, Fabiani F, De Rosa N, De Gisi S, Malara N, Savino R, Rocco G, Chiappetta G, Franco R, Tirino V, Pirozzi G, Viglietto G.

Cell Cycle. 2008 Mar 1;7(5):665-9. Epub 2007 Dec 26.

PMID:
18256540
31.

Loss of p27 expression through RAS-->BRAF-->MAP kinase-dependent pathway in human thyroid carcinomas.

Motti ML, De Marco C, Califano D, De Gisi S, Malanga D, Troncone G, Persico A, Losito S, Fabiani F, Santoro M, Chiappetta G, Fusco A, Viglietto G.

Cell Cycle. 2007 Nov 15;6(22):2817-25. Epub 2007 Aug 13.

PMID:
18032931
32.

The active translation of MHCII mRNA during dendritic cells maturation supplies new molecules to the cell surface pool.

Malanga D, Barba P, Harris PE, Maffei A, Del Pozzo G.

Cell Immunol. 2007 Apr;246(2):75-80. Epub 2007 Jul 27.

PMID:
17662701
33.

Overexpression of the S-phase kinase-associated protein 2 in thyroid cancer.

Chiappetta G, De Marco C, Quintiero A, Califano D, Gherardi S, Malanga D, Scrima M, Montero-Conde C, Cito L, Monaco M, Motti ML, Pasquinelli R, Agosti V, Robledo M, Fusco A, Viglietto G.

Endocr Relat Cancer. 2007 Jun;14(2):405-20.

PMID:
17639054
34.

Comparative analysis of new innovative vaccine formulations based on the use of procaryotic display systems.

D'Apice L, Sartorius R, Caivano A, Mascolo D, Del Pozzo G, Di Mase DS, Ricca E, Li Pira G, Manca F, Malanga D, De Palma R, De Berardinis P.

Vaccine. 2007 Mar 1;25(11):1993-2000. Epub 2006 Dec 5.

PMID:
17239998
35.

Effect of interferon alpha on MHC class II gene expression in ex vivo human islet tissue.

Harris PE, Malanga D, Liu Z, Hardy MA, Souza F, Del Pozzo G, Winchester RJ, Maffei A.

Biochim Biophys Acta. 2006 Jun;1762(6):627-35. Epub 2006 May 13.

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