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Items: 10


A Mucin 16 bispecific T cell-engaging antibody for the treatment of ovarian cancer.

Crawford A, Haber L, Kelly MP, Vazzana K, Canova L, Ram P, Pawashe A, Finney J, Jalal S, Chiu D, Colleton CA, Garnova E, Makonnen S, Hickey C, Krueger P, DelFino F, Potocky T, Kuhnert J, Godin S, Retter MW, Duramad P, MacDonald D, Olson WC, Fairhurst J, Huang T, Martin J, Lin JC, Smith E, Thurston G, Kirshner JR.

Sci Transl Med. 2019 Jun 19;11(497). pii: eaau7534. doi: 10.1126/scitranslmed.aau7534.


Antibody drug conjugates of cleavable amino-alkyl and aryl maytansinoids.

Nittoli T, Kelly MP, Delfino F, Rudge J, Kunz A, Markotan T, Spink J, Chen Z, Shan J, Navarro E, Tait M, Provoncha K, Giurleo J, Zhao F, Jiang X, Hylton D, Makonnen S, Hickey C, Kirshner JR, Thurston G, Papadopoulos N.

Bioorg Med Chem. 2018 May 15;26(9):2271-2279. doi: 10.1016/j.bmc.2018.02.025. Epub 2018 Feb 21.


Preclinical Activity of the Novel Anti-Prolactin Receptor (PRLR) Antibody-Drug Conjugate REGN2878-DM1 in PRLR-Positive Breast Cancers.

Kelly MP, Hickey C, Makonnen S, Coetzee S, Jalal S, Wang Y, Delfino F, Shan J, Potocky TB, Chatterjee I, Andreev J, Kunz A, D'Souza C, Giurleo JT, Nittoli T, Trail PA, Thurston G, Kirshner JR.

Mol Cancer Ther. 2017 Jul;16(7):1299-1311. doi: 10.1158/1535-7163.MCT-16-0839. Epub 2017 Apr 4.


Oxygen pressures in the interstitial space of skeletal muscle and tumors in vivo.

Wilson DF, Lee WM, Makonnen S, Apreleva S, Vinogradov SA.

Adv Exp Med Biol. 2008;614:53-62. doi: 10.1007/978-0-387-74911-2_7.


Hemodynamic responses to antivascular therapy and ionizing radiation assessed by diffuse optical spectroscopies.

Sunar U, Makonnen S, Zhou C, Durduran T, Yu G, Wang HW, Lee WM, Yodh AG.

Opt Express. 2007 Nov 12;15(23):15507-16.


Inhibition of tumor endothelial ERK activation, angiogenesis, and tumor growth by sorafenib (BAY43-9006).

Murphy DA, Makonnen S, Lassoued W, Feldman MD, Carter C, Lee WM.

Am J Pathol. 2006 Nov;169(5):1875-85.


Oxygen pressures in the interstitial space and their relationship to those in the blood plasma in resting skeletal muscle.

Wilson DF, Lee WM, Makonnen S, Finikova O, Apreleva S, Vinogradov SA.

J Appl Physiol (1985). 2006 Dec;101(6):1648-56. Epub 2006 Aug 3.


Ionizing radiation inhibits tumor neovascularization by inducing ineffective angiogenesis.

Tsai JH, Makonnen S, Feldman M, Sehgal CM, Maity A, Lee WM.

Cancer Biol Ther. 2005 Dec;4(12):1395-1400.


Selective cytokine inhibitory drugs with enhanced antiangiogenic activity control tumor growth through vascular inhibition.

Gee MS, Makonnen S, al-Kofahi K, Roysam B, Payvandi F, Man HW, Muller GW, Lee WM.

Cancer Res. 2003 Dec 1;63(23):8073-8.


Tumor vessel development and maturation impose limits on the effectiveness of anti-vascular therapy.

Gee MS, Procopio WN, Makonnen S, Feldman MD, Yeilding NM, Lee WM.

Am J Pathol. 2003 Jan;162(1):183-93.

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