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Items: 16

1.

An unusual genomic variant of pancreatic ductal adenocarcinoma with an indolent clinical course.

Kohutek ZA, Rosati LM, Hong J, Poling J, Attiyeh MA, Makohon-Moore A, Herman JM, Iacobuzio-Donahue CA.

Cold Spring Harb Mol Case Stud. 2017 Jul 5;3(4). pii: a001701. doi: 10.1101/mcs.a001701. Print 2017 Jul.

2.

Tumor diversity and evolution revealed through RADseq.

Perry EB, Makohon-Moore A, Zheng C, Kaufman CK, Cai J, Iacobuzio-Donahue CA, White RM.

Oncotarget. 2017 Jun 27;8(26):41792-41805. doi: 10.18632/oncotarget.18355.

3.

Local recurrences at the anastomotic area are clonally related to the primary tumor in sporadic colorectal carcinoma.

Vakiani E, Shah RH, Berger MF, Makohon-Moore AP, Reiter JG, Ostrovnaya I, Attiyeh MA, Cercek A, Shia J, Iacobuzio-Donahue CA, Solit DB, Weiser MR.

Oncotarget. 2017 Jun 27;8(26):42487-42494. doi: 10.18632/oncotarget.17200.

4.

Transcriptional Mechanisms of Resistance to Anti-PD-1 Therapy.

Ascierto ML, Makohon-Moore A, Lipson EJ, Taube JM, McMiller TL, Berger AE, Fan J, Kaunitz GJ, Cottrell TR, Kohutek ZA, Favorov A, Makarov V, Riaz N, Chan TA, Cope L, Hruban RH, Pardoll DM, Taylor BS, Solit DB, Iacobuzio-Donahue CA, Topalian SL.

Clin Cancer Res. 2017 Jun 15;23(12):3168-3180. doi: 10.1158/1078-0432.CCR-17-0270. Epub 2017 Feb 13.

5.

Reconstructing metastatic seeding patterns of human cancers.

Reiter JG, Makohon-Moore AP, Gerold JM, Bozic I, Chatterjee K, Iacobuzio-Donahue CA, Vogelstein B, Nowak MA.

Nat Commun. 2017 Jan 31;8:14114. doi: 10.1038/ncomms14114.

6.

Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis.

McDonald OG, Li X, Saunders T, Tryggvadottir R, Mentch SJ, Warmoes MO, Word AE, Carrer A, Salz TH, Natsume S, Stauffer KM, Makohon-Moore A, Zhong Y, Wu H, Wellen KE, Locasale JW, Iacobuzio-Donahue CA, Feinberg AP.

Nat Genet. 2017 Mar;49(3):367-376. doi: 10.1038/ng.3753. Epub 2017 Jan 16.

7.

Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer.

Makohon-Moore AP, Zhang M, Reiter JG, Bozic I, Allen B, Kundu D, Chatterjee K, Wong F, Jiao Y, Kohutek ZA, Hong J, Attiyeh M, Javier B, Wood LD, Hruban RH, Nowak MA, Papadopoulos N, Kinzler KW, Vogelstein B, Iacobuzio-Donahue CA.

Nat Genet. 2017 Mar;49(3):358-366. doi: 10.1038/ng.3764. Epub 2017 Jan 16.

8.

Mutant p53 Together with TGFβ Signaling Influence Organ-Specific Hematogenous Colonization Patterns of Pancreatic Cancer.

Zhong Y, Macgregor-Das A, Saunders T, Whittle MC, Makohon-Moore A, Kohutek ZA, Poling J, Herbst BT, Javier BM, Cope L, Leach SD, Hingorani SR, Iacobuzio-Donahue CA.

Clin Cancer Res. 2017 Mar 15;23(6):1607-1620. doi: 10.1158/1078-0432.CCR-15-1615. Epub 2016 Sep 16.

9.

Pancreatic cancer biology and genetics from an evolutionary perspective.

Makohon-Moore A, Iacobuzio-Donahue CA.

Nat Rev Cancer. 2016 Sep;16(9):553-65. doi: 10.1038/nrc.2016.66. Epub 2016 Jul 22. Review.

10.

Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer.

Roberts NJ, Norris AL, Petersen GM, Bondy ML, Brand R, Gallinger S, Kurtz RC, Olson SH, Rustgi AK, Schwartz AG, Stoffel E, Syngal S, Zogopoulos G, Ali SZ, Axilbund J, Chaffee KG, Chen YC, Cote ML, Childs EJ, Douville C, Goes FS, Herman JM, Iacobuzio-Donahue C, Kramer M, Makohon-Moore A, McCombie RW, McMahon KW, Niknafs N, Parla J, Pirooznia M, Potash JB, Rhim AD, Smith AL, Wang Y, Wolfgang CL, Wood LD, Zandi PP, Goggins M, Karchin R, Eshleman JR, Papadopoulos N, Kinzler KW, Vogelstein B, Hruban RH, Klein AP.

Cancer Discov. 2016 Feb;6(2):166-75. doi: 10.1158/2159-8290.CD-15-0402. Epub 2015 Dec 9.

11.

Widespread somatic L1 retrotransposition occurs early during gastrointestinal cancer evolution.

Ewing AD, Gacita A, Wood LD, Ma F, Xing D, Kim MS, Manda SS, Abril G, Pereira G, Makohon-Moore A, Looijenga LH, Gillis AJ, Hruban RH, Anders RA, Romans KE, Pandey A, Iacobuzio-Donahue CA, Vogelstein B, Kinzler KW, Kazazian HH Jr, Solyom S.

Genome Res. 2015 Oct;25(10):1536-45. doi: 10.1101/gr.196238.115. Epub 2015 Aug 10.

12.

Retrotransposon insertions in the clonal evolution of pancreatic ductal adenocarcinoma.

Rodić N, Steranka JP, Makohon-Moore A, Moyer A, Shen P, Sharma R, Kohutek ZA, Huang CR, Ahn D, Mita P, Taylor MS, Barker NJ, Hruban RH, Iacobuzio-Donahue CA, Boeke JD, Burns KH.

Nat Med. 2015 Sep;21(9):1060-4. doi: 10.1038/nm.3919. Epub 2015 Aug 10.

13.

Transflip mutations produce deletions in pancreatic cancer.

Norris AL, Kamiyama H, Makohon-Moore A, Pallavajjala A, Morsberger LA, Lee K, Batista D, Iacobuzio-Donahue CA, Lin MT, Klein AP, Hruban RH, Wheelan SJ, Eshleman JR.

Genes Chromosomes Cancer. 2015 Aug;54(8):472-481. doi: 10.1002/gcc.22258. Epub 2015 May 29.

14.

Prevalence of filarioid nematodes and trypanosomes in American robins and house sparrows, Chicago USA.

Hamer GL, Anderson TK, Berry GE, Makohon-Moore AP, Crafton JC, Brawn JD, Dolinski AC, Krebs BL, Ruiz MO, Muzzall PM, Goldberg TL, Walker ED.

Int J Parasitol Parasites Wildl. 2012 Dec 12;2:42-9. doi: 10.1016/j.ijppaw.2012.11.005. eCollection 2013 Dec.

15.

Pancreatic cancer genomics: insights and opportunities for clinical translation.

Makohon-Moore A, Brosnan JA, Iacobuzio-Donahue CA.

Genome Med. 2013 Mar 28;5(3):26. doi: 10.1186/gm430. eCollection 2013. Review.

16.

Considerations for sequencing analyses of pancreatic cancer progression and metastasis.

Makohon-Moore A, Iacobuzio-Donahue CA.

Methods Mol Biol. 2013;980:121-9. doi: 10.1007/978-1-62703-287-2_6. Review.

PMID:
23359151

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