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Items: 34

1.

Development of the clinical candidate PBD-C06, a humanized pGlu3-Aβ-specific antibody against Alzheimer's disease with reduced complement activation.

Hettmann T, Gillies SD, Kleinschmidt M, Piechotta A, Makioka K, Lemere CA, Schilling S, Rahfeld JU, Lues I.

Sci Rep. 2020 Feb 24;10(1):3294. doi: 10.1038/s41598-020-60319-5.

2.

A Case of Anti-LRP4 Antibody-associated Myasthenia Gravis with a Rare Complication of Thymoma Successfully Treated by Thymectomy.

Aoki S, Nagashima K, Furuta M, Makioka K, Fujita Y, Saito K, Kashima T, Nakajima N, Ikota H, Higuchi O, Ikeda Y.

Intern Med. 2020 Feb 12. doi: 10.2169/internalmedicine.3828-19. [Epub ahead of print]

3.

Clinical usefulness of scales for evaluating cognitive impairment in patients with amyotrophic lateral sclerosis.

Nagashima K, Makioka K, Fujita Y, Ikeda M, Ikeda Y.

J Neurol Sci. 2019 Oct 15;405:116414. doi: 10.1016/j.jns.2019.07.032. Epub 2019 Jul 31.

PMID:
31419623
4.

Deep White Matter Lesions Are Associated with Early Recognition of Dementia in Alzheimer's Disease.

Kasahara H, Ikeda M, Nagashima K, Fujita Y, Makioka K, Tsukagoshi S, Yamazaki T, Takai E, Sanada E, Kobayashi A, Kishi K, Suto T, Higuchi T, Tsushima Y, Ikeda Y.

J Alzheimers Dis. 2019;68(2):797-808. doi: 10.3233/JAD-180939.

PMID:
30775989
5.

Temporal Changes on 123I-Iomazenil and Cerebral Blood Flow Single-photon Emission Computed Tomography in a Patient with Anti-N-methyl-D-aspartate Receptor Encephalitis.

Kasahara H, Sato M, Nagamine S, Makioka K, Tanaka K, Ikeda Y.

Intern Med. 2019 May 15;58(10):1501-1505. doi: 10.2169/internalmedicine.0987-18. Epub 2019 Feb 1.

6.

Progressive Pseudolithiasis Associated with the Intravenous Administration of Ceftriaxone in Patients with Central Nervous System Infections.

Tsukagoshi S, Ishizawa K, Hirayanagi K, Nagamine S, Makioka K, Fujita Y, Ikeda Y.

Intern Med. 2017 Dec 1;56(23):3189-3192. doi: 10.2169/internalmedicine.8826-17. Epub 2017 Oct 11.

7.

Bilateral striatal necrosis caused by a founder mitochondrial 14459G>A mutation in two independent Japanese families.

Hirayanagi K, Okamoto Y, Takai E, Ishizawa K, Makioka K, Fujita Y, Kaneko Y, Tanaka M, Takashima H, Ikeda Y.

J Neurol Sci. 2017 Jul 15;378:177-181. doi: 10.1016/j.jns.2017.05.015. Epub 2017 May 10.

PMID:
28566160
8.

The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis.

Imamura K, Izumi Y, Watanabe A, Tsukita K, Woltjen K, Yamamoto T, Hotta A, Kondo T, Kitaoka S, Ohta A, Tanaka A, Watanabe D, Morita M, Takuma H, Tamaoka A, Kunath T, Wray S, Furuya H, Era T, Makioka K, Okamoto K, Fujisawa T, Nishitoh H, Homma K, Ichijo H, Julien JP, Obata N, Hosokawa M, Akiyama H, Kaneko S, Ayaki T, Ito H, Kaji R, Takahashi R, Yamanaka S, Inoue H.

Sci Transl Med. 2017 May 24;9(391). pii: eaaf3962. doi: 10.1126/scitranslmed.aaf3962.

9.

An analysis of prognostic factors after percutaneous endoscopic gastrostomy placement in Japanese patients with amyotrophic lateral sclerosis.

Nagashima K, Furuta N, Makioka K, Fujita Y, Ikeda M, Ikeda Y.

J Neurol Sci. 2017 May 15;376:202-205. doi: 10.1016/j.jns.2017.03.029. Epub 2017 Mar 21.

PMID:
28431613
10.

A case of severe chronic inflammatory demyelinating polyradiculoneuropathy with monoclonal gammopathy of undetermined significance with alternating immunoglobulin class to IgM from IgA.

Hayashi S, Nagamine S, Makioka K, Kusunoki S, Okamoto K.

Rinsho Shinkeigaku. 2016 Sep 29;56(9):593-9. doi: 10.5692/clinicalneurol.cn-000889. Epub 2016 Aug 31. Japanese.

PMID:
27580763
11.

Immunolocalization of Tom1 in relation to protein degradation systems in Alzheimer's disease.

Makioka K, Yamazaki T, Takatama M, Ikeda M, Murayama S, Okamoto K, Ikeda Y.

J Neurol Sci. 2016 Jun 15;365:101-7. doi: 10.1016/j.jns.2016.03.035. Epub 2016 Apr 13.

PMID:
27206884
12.

Juvenile-onset Sporadic Amyotrophic Lateral Sclerosis with a Frameshift FUS Gene Mutation Presenting Unique Neuroradiological Findings and Cognitive Impairment.

Hirayanagi K, Sato M, Furuta N, Makioka K, Ikeda Y.

Intern Med. 2016;55(6):689-93. doi: 10.2169/internalmedicine.55.5569. Epub 2016 Mar 15.

13.

Hypersialylation is a common feature of neurofibrillary tangles and granulovacuolar degenerations in Alzheimer's disease and tauopathy brains.

Nagamine S, Yamazaki T, Makioka K, Fujita Y, Ikeda M, Takatama M, Okamoto K, Yokoo H, Ikeda Y.

Neuropathology. 2016 Aug;36(4):333-45. doi: 10.1111/neup.12277. Epub 2015 Dec 21.

PMID:
26685795
14.

Anti-Hu Antibody-associated Paraneoplastic Neurological Syndrome Showing Peripheral Neuropathy and Atypical Multifocal Brain Lesions.

Shibata M, Uchida M, Tsukagoshi S, Yamaguchi K, Yamaguchi A, Furuta N, Makioka K, Maeno T, Fujita Y, Kurabayashi M, Ikeda Y.

Intern Med. 2015;54(23):3057-60. doi: 10.2169/internalmedicine.54.4867. Epub 2015 Dec 1.

15.

Anti-MuSK Antibody-positive Myasthenia Gravis Mimicking Amyotrophic Lateral Sclerosis.

Furuta N, Ishizawa K, Shibata M, Tsukagoshi S, Nagamine S, Makioka K, Fujita Y, Ikeda M, Yoshimura S, Motomura M, Okamoto K, Ikeda Y.

Intern Med. 2015;54(19):2497-501. doi: 10.2169/internalmedicine.54.4645. Epub 2015 Oct 1.

16.

[A case of neurolymphomatosis presenting extended involvement of spinal nerve roots].

Sato M, Furuta M, Hirayanagi K, Nagamine S, Makioka K, Ikeda Y.

Rinsho Shinkeigaku. 2015;55(5):333-8. doi: 10.5692/clinicalneurol.cn-000615. Japanese.

PMID:
26028196
17.

Reversal of leukoencephalopathy induced by liposomal amphotericin B in a patient with cryptococcal meningitis.

Sato M, Hirayanagi K, Makioka K, Ikeda Y.

J Neurol Sci. 2015 Mar 15;350(1-2):118-9. doi: 10.1016/j.jns.2015.02.024. Epub 2015 Feb 18. No abstract available.

PMID:
25724871
18.

CSF levels of Aβ1-38/Aβ1-40/Aβ1-42 and (11)C PiB-PET studies in three clinical variants of primary progressive aphasia and Alzheimer's disease.

Ikeda M, Tashiro Y, Takai E, Kurose S, Fugami N, Tsuda K, Arisaka Y, Kodaira S, Fujita Y, Makioka K, Mizuno Y, Shimada H, Harigaya Y, Takatama M, Amari M, Yamazaki T, Yamaguchi H, Higuchi T, Okamoto K, Tsushima Y, Ikeda Y.

Amyloid. 2014 Dec;21(4):238-45. doi: 10.3109/13506129.2014.949231. Epub 2014 Aug 20.

PMID:
25139672
19.

Cytoplasmic TDP-43 accumulation in cells of the adrenal medulla in individuals with or without amyotrophic lateral sclerosis.

Okamoto K, Amari M, Fujita Y, Makioka K, Fukuda T, Suzuki K, Takatama M.

Neuropathology. 2014 Dec;34(6):535-40. doi: 10.1111/neup.12139. Epub 2014 Jul 11.

PMID:
25039310
20.

Parkinson's disease presenting with oculogyric crisis in the off period.

Furuta N, Furuta M, Makioka K, Fujita Y, Okamoto K.

Intern Med. 2014;53(7):793-5. Epub 2012 Mar 1.

21.

Immunolocalization of Smurf1 in Hirano bodies.

Makioka K, Yamazaki T, Takatama M, Ikeda M, Okamoto K.

J Neurol Sci. 2014 Jan 15;336(1-2):24-8. doi: 10.1016/j.jns.2013.09.028. Epub 2013 Sep 26.

PMID:
24238996
22.

Changes in the clinical features of amyotrophic lateral sclerosis in rural Japan.

Furuta N, Makioka K, Fujita Y, Okamoto K.

Intern Med. 2013;52(15):1691-6. Epub 2012 Mar 1.

23.

Response to comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells".

Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, Ayaki T, Ito H, Yoshikawa K, Yamawaki S, Suzuki S, Watanabe D, Hioki H, Kaneko T, Makioka K, Okamoto K, Takuma H, Tamaoka A, Hasegawa K, Nonaka T, Hasegawa M, Kawata A, Yoshida M, Nakahata T, Takahashi R, Marchetto MC, Gage FH, Yamanaka S, Inoue H.

Sci Transl Med. 2013 Jun 5;5(188):188lr2. doi: 10.1126/scitranslmed.3005697.

24.

Cerebrospinal fluid levels of phosphorylated tau and Aβ1-38/Aβ1-40/Aβ1-42 in Alzheimer's disease with PS1 mutations.

Ikeda M, Yonemura K, Kakuda S, Tashiro Y, Fujita Y, Takai E, Hashimoto Y, Makioka K, Furuta N, Ishiguro K, Maruki R, Yoshida J, Miyaguchi O, Tsukie T, Kuwano R, Yamazaki T, Yamaguchi H, Amari M, Takatama M, Harigaya Y, Okamoto K.

Amyloid. 2013 Jun;20(2):107-12. doi: 10.3109/13506129.2013.790810. Epub 2013 May 2.

PMID:
23638752
25.

Accumulation of phosphorylated TDP-43 in the CNS of a patient with Cockayne syndrome.

Sakurai A, Makioka K, Fukuda T, Takatama M, Okamoto K.

Neuropathology. 2013 Dec;33(6):673-7. doi: 10.1111/neup.12038. Epub 2013 Apr 14.

PMID:
23581709
26.

Reduced expression of BTBD10 in anterior horn cells with Golgi fragmentation and pTDP-43-positive inclusions in patients with sporadic amyotrophic lateral sclerosis.

Furuta N, Makioka K, Fujita Y, Ikeda M, Takatama M, Matsuoka M, Okamoto K.

Neuropathology. 2013 Aug;33(4):397-404. doi: 10.1111/neup.12010. Epub 2013 Jan 16.

PMID:
23320755
27.

Encephalopathy with amyloid angiopathy and numerous amyloid plaques with low levels of CSF Aβ1-40/Aβ1-42.

Ikeda M, Hirayanagi K, Arai M, Kakuda S, Makioka K, Furuta N, Takai E, Kasahara H, Tsukagoshi S, Fujita Y, Amari M, Takatama M, Nakazato Y, Okamoto K.

Amyloid. 2012 Dec;19(4):186-90. doi: 10.3109/13506129.2012.725113. Epub 2012 Sep 21.

PMID:
22994303
28.

Drug screening for ALS using patient-specific induced pluripotent stem cells.

Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, Ayaki T, Ito H, Yoshikawa K, Yamawaki S, Suzuki S, Watanabe D, Hioki H, Kaneko T, Makioka K, Okamoto K, Takuma H, Tamaoka A, Hasegawa K, Nonaka T, Hasegawa M, Kawata A, Yoshida M, Nakahata T, Takahashi R, Marchetto MC, Gage FH, Yamanaka S, Inoue H.

Sci Transl Med. 2012 Aug 1;4(145):145ra104. doi: 10.1126/scitranslmed.3004052.

29.

Activation and alteration of lysosomes in multiple system atrophy.

Makioka K, Yamazaki T, Takatama M, Nakazato Y, Okamoto K.

Neuroreport. 2012 Mar 28;23(5):270-6. doi: 10.1097/WNR.0b013e3283503e4f.

PMID:
22343695
30.

Involvement of endoplasmic reticulum stress defined by activated unfolded protein response in multiple system atrophy.

Makioka K, Yamazaki T, Fujita Y, Takatama M, Nakazato Y, Okamoto K.

J Neurol Sci. 2010 Oct 15;297(1-2):60-5. doi: 10.1016/j.jns.2010.06.019. Epub 2010 Jul 29.

PMID:
20667553
31.

Phosphorylation-dependent TDP-43 antibody detects intraneuronal dot-like structures showing morphological characters of granulovacuolar degeneration.

Kadokura A, Yamazaki T, Kakuda S, Makioka K, Lemere CA, Fujita Y, Takatama M, Okamoto K.

Neurosci Lett. 2009 Sep 29;463(1):87-92. doi: 10.1016/j.neulet.2009.06.024. Epub 2009 Jun 17.

PMID:
19539703
32.

Familial amyloid polyneuropathy (Finnish type) presenting multiple cranial nerve deficits with carpal tunnel syndrome and orthostatic hypotension.

Makioka K, Ikeda M, Ikeda Y, Nakasone A, Osawa T, Sasaki A, Otani T, Arai M, Okamoto K.

Neurol Res. 2010 Jun;32(5):472-5. doi: 10.1179/174313209X409007. Epub 2009 May 6.

PMID:
19422734
33.

Variations in the effects on synthesis of amyloid beta protein in modulated autophagic conditions.

Makioka K, Yamazaki T, Kakuda S, Okamoto K.

Neurol Res. 2009 Nov;31(9):959-68. doi: 10.1179/174313209X395463. Epub 2009 Feb 11.

PMID:
19215663
34.

Familial amyloid polyneuropathy (Finnish type) in a Japanese family: Clinical features and immunocytochemical studies.

Ikeda M, Mizushima K, Fujita Y, Watanabe M, Sasaki A, Makioka K, Enoki M, Nakamura M, Otani T, Takatama M, Okamoto K.

J Neurol Sci. 2007 Jan 15;252(1):4-8. Epub 2006 Nov 13.

PMID:
17097682

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