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Items: 17

1.

Efficacy of a new intravenous β2-adrenergic agonist (bedoradrine, MN-221) for patients with an acute exacerbation of asthma.

House SL, Matsuda K, O'Brien G, Makhay M, Iwaki Y, Ferguson I, Lovato LM, Lewis LM.

Respir Med. 2015 Oct;109(10):1268-73. doi: 10.1016/j.rmed.2015.08.003. Epub 2015 Aug 14.

2.

Evaluation of bedoradrine sulfate (MN-221), a novel, highly selective beta2-adrenergic receptor agonist for the treatment of asthma via intravenous infusion.

Matsuda K, Makhay M, Johnson K, Iwaki Y.

J Asthma. 2012 Dec;49(10):1071-8. doi: 10.3109/02770903.2012.729631. Epub 2012 Oct 25.

PMID:
23094708
3.

Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inverse agonist.

Vanover KE, Weiner DM, Makhay M, Veinbergs I, Gardell LR, Lameh J, Del Tredici AL, Piu F, Schiffer HH, Ott TR, Burstein ES, Uldam AK, Thygesen MB, Schlienger N, Andersson CM, Son TY, Harvey SC, Powell SB, Geyer MA, Tolf BR, Brann MR, Davis RE.

J Pharmacol Exp Ther. 2006 May;317(2):910-8. Epub 2006 Feb 9.

PMID:
16469866
4.

Pharmacological characterization of AC-90179 [2-(4-methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide hydrochloride]: a selective serotonin 2A receptor inverse agonist.

Vanover KE, Harvey SC, Son T, Bradley SR, Kold H, Makhay M, Veinbergs I, Spalding TA, Weiner DM, Andersson CM, Tolf BR, Brann MR, Hacksell U, Davis RE.

J Pharmacol Exp Ther. 2004 Sep;310(3):943-51. Epub 2004 Apr 21.

PMID:
15102927
5.

Discriminative stimulus effects of the type-4 phosphodiesterase inhibitor rolipram in rats.

Makhay MM, Houslay MD, O'Donnell JM.

Psychopharmacology (Berl). 2001 Nov;158(3):297-304.

PMID:
11713620
6.

Discriminative stimulus effects of centrally administered isoproterenol in rats: mediation by beta-1 adrenergic receptors.

Crissman AM, Makhay MM, O'Donnell JM.

Psychopharmacology (Berl). 2001 Feb;154(1):70-5.

PMID:
11292008
7.

Noradrenergic lesions differentially alter the expression of two subtypes of low Km cAMP-sensitive phosphodiesterase type 4 (PDE4A and PDE4B) in rat brain.

Farooqui SM, Zhang K, Makhay M, Jackson K, Farooqui SQ, Cherry JA, O'Donnell JM.

Brain Res. 2000 Jun 9;867(1-2):52-61.

PMID:
10837797
8.

Effects of antidepressants in rats trained to discriminate the beta-2 adrenergic agonist clenbuterol.

Makhay MM, O'Donnell JM.

Pharmacol Biochem Behav. 1999 Jun;63(2):319-24.

PMID:
10371662
9.

Establishing morphine and U-50,488H as discriminative stimuli in a three-choice assay with pigeons.

Makhay MM, Young AM, Poling A.

Exp Clin Psychopharmacol. 1998 Feb;6(1):3-9.

PMID:
9526141
10.

Behavioral contingencies modulate tolerance to discriminative stimulus effects of morphine.

Young AM, McMullen WJ, Makhay MM, Goushaw PJ.

Psychopharmacology (Berl). 1996 Jun;125(3):220-30.

PMID:
8815957
11.

Effects of (+)-fenfluramine on 3,4-methylenedioxymethamphetamine (MDMA) discrimination in rats.

Baker LE, Makhay MM.

Pharmacol Biochem Behav. 1996 Feb;53(2):455-61.

PMID:
8808158
12.

In vivo apparent pA2 analysis for naltrexone antagonism of discriminative stimulus and analgesic effects of opiate agonists in rats.

Walker EA, Makhay MM, House JD, Young AM.

J Pharmacol Exp Ther. 1994 Nov;271(2):959-68.

PMID:
7965818
13.

The effects of d-amphetamine and diazepam on schedule-induced defecation in rats.

LeSage M, Makhay M, DeLeon I, Poling A.

Pharmacol Biochem Behav. 1994 Jul;48(3):787-90.

PMID:
7938136
14.

Effects of cocaine on fixed-ratio responding of rats: modulation by required response force.

Makhay M, Alling K, Poling A.

Pharmacol Biochem Behav. 1994 Jun;48(2):511-4.

PMID:
8090823
15.

Effects of d-amphetamine and ethosuximide on responding under delayed-matching-to-sample procedures with differential and nondifferential outcomes.

Poling A, Alling K, Makhay M, Nickel M, Blakely E, Roman M, Schlinger H.

Pharmacol Biochem Behav. 1992 Aug;42(4):871-7.

PMID:
1513870
16.

Onset of tolerance to discriminative stimulus effects of morphine.

Young AM, Steigerwald ES, Makhay MM, Kapitsopoulos G.

Pharmacol Biochem Behav. 1991 Jun;39(2):487-93.

PMID:
1658819
17.

Tolerance to morphine-like stimulus effects of mu opioid agonists.

Young AM, Kapitsopoulos G, Makhay MM.

J Pharmacol Exp Ther. 1991 May;257(2):795-805.

PMID:
2033521

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