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DISC1 regulates N-methyl-D-aspartate receptor dynamics: abnormalities induced by a Disc1 mutation modelling a translocation linked to major mental illness.

Malavasi ELV, Economides KD, Grünewald E, Makedonopoulou P, Gautier P, Mackie S, Murphy LC, Murdoch H, Crummie D, Ogawa F, McCartney DL, O'Sullivan ST, Burr K, Torrance HS, Phillips J, Bonneau M, Anderson SM, Perry P, Pearson M, Constantinides C, Davidson-Smith H, Kabiri M, Duff B, Johnstone M, Polites HG, Lawrie SM, Blackwood DH, Semple CA, Evans KL, Didier M, Chandran S, McIntosh AM, Price DJ, Houslay MD, Porteous DJ, Millar JK.

Transl Psychiatry. 2018 Sep 6;8(1):184. doi: 10.1038/s41398-018-0228-1.


Development and validation of a direct sandwich chemiluminescence immunoassay for measuring DNA adducts of benzo[a]pyrene and other polycyclic aromatic hydrocarbons.

Georgiadis P, Kovács K, Kaila S, Makedonopoulou P, Anna L, Poirier MC, Knudsen LE, Schoket B, Kyrtopoulos SA.

Mutagenesis. 2012 Sep;27(5):589-97. doi: 10.1093/mutage/ges024. Epub 2012 May 18.


A t(1;11) translocation linked to schizophrenia and affective disorders gives rise to aberrant chimeric DISC1 transcripts that encode structurally altered, deleterious mitochondrial proteins.

Eykelenboom JE, Briggs GJ, Bradshaw NJ, Soares DC, Ogawa F, Christie S, Malavasi EL, Makedonopoulou P, Mackie S, Malloy MP, Wear MA, Blackburn EA, Bramham J, McIntosh AM, Blackwood DH, Muir WJ, Porteous DJ, Millar JK.

Hum Mol Genet. 2012 Aug 1;21(15):3374-86. doi: 10.1093/hmg/dds169. Epub 2012 Apr 30.


Development and validation of a new, sensitive immunochemical assay for O⁶-methylguanine in DNA and its application in a population study.

Georgiadis P, Kaila S, Makedonopoulou P, Fthenou E, Chatzi L, Pletsa V, Kyrtopoulos SA.

Cancer Epidemiol Biomarkers Prev. 2011 Jan;20(1):82-90. doi: 10.1158/1055-9965.EPI-10-0788. Epub 2010 Nov 16.

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