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Items: 1 to 50 of 90

1.

Establishment of the Dual Humanized TK-NOG Mouse Model for HIV-associated Liver Pathogenesis.

Dagur RS, Wang W, Makarov E, Sun Y, Poluektova LY.

J Vis Exp. 2019 Sep 11;(151). doi: 10.3791/58645.

2.

Acetaldehyde suppresses the display of HBV-MHC class I complexes on HBV-expressing hepatocytes.

Ganesan M, Krutik VM, Makarov E, Mathews S, Kharbanda KK, Poluektova LY, Casey CA, Osna NA.

Am J Physiol Gastrointest Liver Physiol. 2019 Aug 1;317(2):G127-G140. doi: 10.1152/ajpgi.00064.2019. Epub 2019 May 29.

PMID:
31141391
3.

Presence and distribution of progerin in HGPS cells is ameliorated by drugs that impact on the mevalonate and mTOR pathways.

Clements CS, Bikkul MU, Ofosu W, Eskiw C, Tree D, Makarov E, Kill IR, Bridger JM.

Biogerontology. 2019 Jun;20(3):337-358. doi: 10.1007/s10522-019-09807-4. Epub 2019 Apr 30.

4.

Full-length human surfactant protein A inhibits influenza A virus infection of A549 lung epithelial cells: A recombinant form containing neck and lectin domains promotes infectivity.

Al-Qahtani AA, Murugaiah V, Bashir HA, Pathan AA, Abozaid SM, Makarov E, Nal-Rogier B, Kishore U, Al-Ahdal MN.

Immunobiology. 2019 May;224(3):408-418. doi: 10.1016/j.imbio.2019.02.006. Epub 2019 Feb 11.

5.

Human Interleukin-34 facilitates microglia-like cell differentiation and persistent HIV-1 infection in humanized mice.

Mathews S, Branch Woods A, Katano I, Makarov E, Thomas MB, Gendelman HE, Poluektova LY, Ito M, Gorantla S.

Mol Neurodegener. 2019 Mar 5;14(1):12. doi: 10.1186/s13024-019-0311-y.

6.

Relationship between serologic profile (ANCA type) and clinical features of renal involvement in ANCA-associated vasculitides.

Bulanov NM, Makarov EA, Shchegoleva EM, Zykova AS, Vinogradova ES, Novikov PI, Lysenko Kozlovskaya LV, Moiseev SV.

Ter Arkh. 2018 Jun 20;90(6):15-21. doi: 10.26442/terarkh201890615-21.

PMID:
30701899
7.

Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson-Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform.

Bikkul MU, Faragher RGA, Worthington G, Meinke P, Kerr ARW, Sammy A, Riyahi K, Horton D, Schirmer EC, Hubank M, Kill IR, Anderson RM, Slijepcevic P, Makarov E, Bridger JM.

Genes Chromosomes Cancer. 2019 Jun;58(6):341-356. doi: 10.1002/gcc.22711. Epub 2019 Jan 7.

8.

Human Properdin Modulates Macrophage: Mycobacterium bovis BCG Interaction via Thrombospondin Repeats 4 and 5.

Al-Mozaini MA, Tsolaki AG, Abdul-Aziz M, Abozaid SM, Al-Ahdal MN, Pathan AA, Murugaiah V, Makarov EM, Kaur A, Sim RB, Kishore U, Kouser L.

Front Immunol. 2018 May 8;9:533. doi: 10.3389/fimmu.2018.00533. eCollection 2018.

9.

Matrix stiffness regulate apoptotic cell death in HIV-HCV co-infected hepatocytes: Importance for liver fibrosis progression.

Ganesan M, Dagur RS, Makarov E, Poluektova LI, Kidambi S, Osna NA.

Biochem Biophys Res Commun. 2018 Jun 7;500(3):717-722. doi: 10.1016/j.bbrc.2018.04.142. Epub 2018 Apr 22.

PMID:
29679566
10.

Antiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG Mice.

McMillan JM, Cobb DA, Lin Z, Banoub MG, Dagur RS, Branch Woods AA, Wang W, Makarov E, Kocher T, Joshi PS, Quadros RM, Harms DW, Cohen SM, Gendelman HE, Gurumurthy CB, Gorantla S, Poluektova LY.

J Pharmacol Exp Ther. 2018 May;365(2):272-280. doi: 10.1124/jpet.117.247288. Epub 2018 Feb 23.

11.

Human hepatocyte depletion in the presence of HIV-1 infection in dual reconstituted humanized mice.

Dagur RS, Wang W, Cheng Y, Makarov E, Ganesan M, Suemizu H, Gebhart CL, Gorantla S, Osna N, Poluektova LY.

Biol Open. 2018 Feb 13;7(2). pii: bio029785. doi: 10.1242/bio.029785.

12.

The rare nonsense mutation in p53 triggers alternative splicing to produce a protein capable of inducing apoptosis.

Makarov EM, Shtam TA, Kovalev RA, Pantina RA, Varfolomeeva EY, Filatov MV.

PLoS One. 2017 Sep 29;12(9):e0185126. doi: 10.1371/journal.pone.0185126. eCollection 2017.

13.

[The frequency of ophthalmologic manifestations of granulomatosis with polyangiitis (Wegener's) and their relationship to systemic diseases].

Ismailova DS, Novikov PI, Grusha YO, Abramova YV, Bulanov NM, Makarov EA.

Ter Arkh. 2017;89(5):69-73. doi: 10.17116/terarkh201789569-73. Russian.

PMID:
28631702
14.

[Correction of functional state of divers during training camps].

Dudelzon VA, Makarov EV, Kalmanov AS, Bulavin VV, Shishkin AN.

Voen Med Zh. 2017 Feb;338(2):49-56. Russian.

PMID:
30593095
15.

Generation of high-intensity spectral supercontinuum of more than two octaves in a water jet.

Tcypkin AN, Putilin SE, Melnik MV, Makarov EA, Bespalov VG, Kozlov SA.

Appl Opt. 2016 Oct 10;55(29):8390-8394. doi: 10.1364/AO.55.008390.

PMID:
27828091
16.

Nanogel-Conjugated Reverse Transcriptase Inhibitors and Their Combinations as Novel Antiviral Agents with Increased Efficacy against HIV-1 Infection.

Senanayake TH, Gorantla S, Makarov E, Lu Y, Warren G, Vinogradov SV.

Mol Pharm. 2015 Dec 7;12(12):4226-36. doi: 10.1021/acs.molpharmaceut.5b00424. Epub 2015 Nov 13.

17.

Influence of age, irradiation and humanization on NSG mouse phenotypes.

Knibbe-Hollinger JS, Fields NR, Chaudoin TR, Epstein AA, Makarov E, Akhter SP, Gorantla S, Bonasera SJ, Gendelman HE, Poluektova LY.

Biol Open. 2015 Sep 9;4(10):1243-52. doi: 10.1242/bio.013201.

18.

Manganese-Enhanced Magnetic Resonance Imaging Reflects Brain Pathology During Progressive HIV-1 Infection of Humanized Mice.

Bade AN, Gorantla S, Dash PK, Makarov E, Sajja BR, Poluektova LY, Luo J, Gendelman HE, Boska MD, Liu Y.

Mol Neurobiol. 2016 Jul;53(5):3286-3297. doi: 10.1007/s12035-015-9258-3. Epub 2015 Jun 11.

19.

[Histone deacetylase inhibitors cause the TP53-dependent induction of p21/Waf1 in tumor cells carrying mutations in TP53].

Kovalev RA, Shtam TA, Karelov DV, Burdakov VS, Volnitskiy AV, Makarov EM, Filatov MV.

Tsitologiia. 2015;57(3):204-11. Russian.

PMID:
26021170
20.

The 35S U5 snRNP Is Generated from the Activated Spliceosome during In vitro Splicing.

Makarova OV, Makarov EM.

PLoS One. 2015 May 28;10(5):e0128430. doi: 10.1371/journal.pone.0128430. eCollection 2015.

21.

Amphiphilic cationic nanogels as brain-targeted carriers for activated nucleoside reverse transcriptase inhibitors.

Warren G, Makarov E, Lu Y, Senanayake T, Rivera K, Gorantla S, Poluektova LY, Vinogradov SV.

J Neuroimmune Pharmacol. 2015 Mar;10(1):88-101. doi: 10.1007/s11481-014-9576-7. Epub 2015 Jan 6.

22.

Associations between brain microstructures, metabolites, and cognitive deficits during chronic HIV-1 infection of humanized mice.

Boska MD, Dash PK, Knibbe J, Epstein AA, Akhter SP, Fields N, High R, Makarov E, Bonasera S, Gelbard HA, Poluektova LY, Gendelman HE, Gorantla S.

Mol Neurodegener. 2014 Dec 18;9:58. doi: 10.1186/1750-1326-9-58.

23.

Venous thromboembolic events in systemic vasculitis.

Novikov P, Makarov E, Moiseev S, Meshkov A, Strizhakov L.

Ann Rheum Dis. 2015 Mar;74(3):e27. doi: 10.1136/annrheumdis-2014-206849. Epub 2014 Nov 7. No abstract available.

PMID:
25381230
24.

Exosomes are natural carriers of exogenous siRNA to human cells in vitro.

Shtam TA, Kovalev RA, Varfolomeeva EY, Makarov EM, Kil YV, Filatov MV.

Cell Commun Signal. 2013 Nov 18;11:88. doi: 10.1186/1478-811X-11-88.

25.

Human hepatocytes and hematolymphoid dual reconstitution in treosulfan-conditioned uPA-NOG mice.

Gutti TL, Knibbe JS, Makarov E, Zhang J, Yannam GR, Gorantla S, Sun Y, Mercer DF, Suemizu H, Wisecarver JL, Osna NA, Bronich TK, Poluektova LY.

Am J Pathol. 2014 Jan;184(1):101-9. doi: 10.1016/j.ajpath.2013.09.008. Epub 2013 Nov 6.

26.

Nano-NRTIs demonstrate low neurotoxicity and high antiviral activity against HIV infection in the brain.

Gerson T, Makarov E, Senanayake TH, Gorantla S, Poluektova LY, Vinogradov SV.

Nanomedicine. 2014 Jan;10(1):177-85. doi: 10.1016/j.nano.2013.06.012. Epub 2013 Jul 9.

27.

Antiviral peptide nanocomplexes as a potential therapeutic modality for HIV/HCV co-infection.

Zhang J, Mulvenon A, Makarov E, Wagoner J, Knibbe J, Kim JO, Osna N, Bronich TK, Poluektova LY.

Biomaterials. 2013 May;34(15):3846-57. doi: 10.1016/j.biomaterials.2013.01.026. Epub 2013 Feb 10.

28.

Multi-terawatt picoseconds 10-μm СО2 laser system: design and parameters' control.

Bravy BG, Chernyshev YA, Gordienko VM, Makarov EF, Panchenko VY, Platonenko VT, Vasil'ev GK.

Opt Express. 2012 Nov 5;20(23):25536-44. doi: 10.1364/OE.20.025536.

PMID:
23187371
29.

Post-transcriptional spliceosomes are retained in nuclear speckles until splicing completion.

Girard C, Will CL, Peng J, Makarov EM, Kastner B, Lemm I, Urlaub H, Hartmuth K, Lührmann R.

Nat Commun. 2012;3:994. doi: 10.1038/ncomms1998.

PMID:
22871813
30.

Functional mammalian spliceosomal complex E contains SMN complex proteins in addition to U1 and U2 snRNPs.

Makarov EM, Owen N, Bottrill A, Makarova OV.

Nucleic Acids Res. 2012 Mar;40(6):2639-52. doi: 10.1093/nar/gkr1056. Epub 2011 Nov 21.

31.

Progeria Research Day at Brunel University.

Bridger JM, Eskiw CH, Makarov EM, Tree D, Kill IR.

Nucleus. 2011 Nov-Dec;2(6):517-22. doi: 10.4161/nucl.2.6.17605. Epub 2011 Nov 1. Review.

32.

Loss of neuronal integrity during progressive HIV-1 infection of humanized mice.

Dash PK, Gorantla S, Gendelman HE, Knibbe J, Casale GP, Makarov E, Epstein AA, Gelbard HA, Boska MD, Poluektova LY.

J Neurosci. 2011 Mar 2;31(9):3148-57. doi: 10.1523/JNEUROSCI.5473-10.2011.

33.

Links between progressive HIV-1 infection of humanized mice and viral neuropathogenesis.

Gorantla S, Makarov E, Finke-Dwyer J, Castanedo A, Holguin A, Gebhart CL, Gendelman HE, Poluektova L.

Am J Pathol. 2010 Dec;177(6):2938-49. doi: 10.2353/ajpath.2010.100536. Epub 2010 Nov 18.

34.

Nano-NRTIs: efficient inhibitors of HIV type-1 in macrophages with a reduced mitochondrial toxicity.

Vinogradov SV, Poluektova LY, Makarov E, Gerson T, Senanayake MT.

Antivir Chem Chemother. 2010 Oct 28;21(1):1-14. doi: 10.3851/IMP1680.

35.

Immunoregulation of a CB2 receptor agonist in a murine model of neuroAIDS.

Gorantla S, Makarov E, Roy D, Finke-Dwyer J, Murrin LC, Gendelman HE, Poluektova L.

J Neuroimmune Pharmacol. 2010 Sep;5(3):456-68. doi: 10.1007/s11481-010-9225-8. Epub 2010 Jun 12.

36.

CD8+ cell depletion accelerates HIV-1 immunopathology in humanized mice.

Gorantla S, Makarov E, Finke-Dwyer J, Gebhart CL, Domm W, Dewhurst S, Gendelman HE, Poluektova LY.

J Immunol. 2010 Jun 15;184(12):7082-91. doi: 10.4049/jimmunol.1000438. Epub 2010 May 21.

37.

A novel splice variant of the DNA-PKcs gene is associated with clinical and cellular radiosensitivity in a patient with xeroderma pigmentosum.

Abbaszadeh F, Clingen PH, Arlett CF, Plowman PN, Bourton EC, Themis M, Makarov EM, Newbold RF, Green MH, Parris CN.

J Med Genet. 2010 Mar;47(3):176-81. doi: 10.1136/jmg.2009.068866. Epub 2009 Sep 24.

38.

Isoforms of U1-70k control subunit dynamics in the human spliceosomal U1 snRNP.

Hernández H, Makarova OV, Makarov EM, Morgner N, Muto Y, Krummel DP, Robinson CV.

PLoS One. 2009 Sep 28;4(9):e7202. doi: 10.1371/journal.pone.0007202.

39.

Study of gene-targeted mouse models of splicing factor gene Prpf31 implicated in human autosomal dominant retinitis pigmentosa (RP).

Bujakowska K, Maubaret C, Chakarova CF, Tanimoto N, Beck SC, Fahl E, Humphries MM, Kenna PF, Makarov E, Makarova O, Paquet-Durand F, Ekström PA, van Veen T, Leveillard T, Humphries P, Seeliger MW, Bhattacharya SS.

Invest Ophthalmol Vis Sci. 2009 Dec;50(12):5927-33. doi: 10.1167/iovs.08-3275. Epub 2009 Jul 2.

PMID:
19578015
40.

Effects of alpha1-acid glycoprotein on hemostasis in experimental septic peritonitis.

Osikov MV, Makarov EV, Krivokhizhina LV.

Bull Exp Biol Med. 2007 Aug;144(2):178-80.

PMID:
18399274
41.

[Influence of alpha-1-acid glycoprotein on blood rheology].

Osikov MV, Krivokhizhina LV, Makarov EV.

Patol Fiziol Eksp Ter. 2007 Jul-Sep;(3):20-1. Russian.

PMID:
17929498
42.
43.

Ceruloplasmin prevents hemostatic disorders during experimental hyperammonemia.

Osikov MV, Makarov EV, Krivokhizhina LV.

Bull Exp Biol Med. 2006 Oct;142(4):416-8. English, Russian.

PMID:
17415425
44.

Organization of core spliceosomal components U5 snRNA loop I and U4/U6 Di-snRNP within U4/U6.U5 Tri-snRNP as revealed by electron cryomicroscopy.

Sander B, Golas MM, Makarov EM, Brahms H, Kastner B, Lührmann R, Stark H.

Mol Cell. 2006 Oct 20;24(2):267-78.

45.

Chromatographic quantitation at losses of analyte during sample preparation. Application of the modified method of double internal standard.

Zenkevich IG, Makarov ED.

J Chromatogr A. 2007 May 25;1150(1-2):117-23. Epub 2006 Sep 25.

PMID:
16996525
46.

Muramyl peptides augment cytotoxic effect of tumor necrosis factor-alpha in combination with cytotoxic drugs on tumor cells.

Petrova EE, Valyakina TI, Simonova MA, Komaleva RL, Khaidukov SV, Makarov EA, Blokhin DY, Ivanov PK, Andronova TM, Nesmeyanov VA.

Int Immunopharmacol. 2006 Sep;6(9):1377-86. Epub 2006 Jan 18.

PMID:
16846831
47.

The human U5 snRNP 52K protein (CD2BP2) interacts with U5-102K (hPrp6), a U4/U6.U5 tri-snRNP bridging protein, but dissociates upon tri-snRNP formation.

Laggerbauer B, Liu S, Makarov E, Vornlocher HP, Makarova O, Ingelfinger D, Achsel T, Lührmann R.

RNA. 2005 May;11(5):598-608.

48.

A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing.

Makarova OV, Makarov EM, Urlaub H, Will CL, Gentzel M, Wilm M, Lührmann R.

EMBO J. 2004 Jun 16;23(12):2381-91. Epub 2004 Jun 3.

49.

[Psychological services in the professional training of the NES (nuclear energy station) operators].

Basov VI, Ipatov PL, Sorokin AV, Makarov EB.

Med Tr Prom Ekol. 2004;(3):17-20. Russian.

PMID:
15124390
50.

Three-dimensional structure of a pre-catalytic human spliceosomal complex B.

Boehringer D, Makarov EM, Sander B, Makarova OV, Kastner B, Lührmann R, Stark H.

Nat Struct Mol Biol. 2004 May;11(5):463-8. Epub 2004 Apr 18.

PMID:
15098019

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