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Items: 1 to 50 of 1308

1.

Reactive oxygen species modulate macrophage immunosuppressive phenotype through the up-regulation of PD-L1.

Roux C, Jafari SM, Shinde R, Duncan G, Cescon DW, Silvester J, Chu MF, Hodgson K, Berger T, Wakeham A, Palomero L, Garcia-Valero M, Pujana MA, Mak TW, McGaha TL, Cappello P, Gorrini C.

Proc Natl Acad Sci U S A. 2019 Feb 15. pii: 201819473. doi: 10.1073/pnas.1819473116. [Epub ahead of print]

PMID:
30770442
2.

Glutathione Metabolism: An Achilles' Heel of ARID1A-Deficient Tumors.

Gorrini C, Mak TW.

Cancer Cell. 2019 Feb 11;35(2):161-163. doi: 10.1016/j.ccell.2019.01.017.

PMID:
30753819
3.

Choline acetyltransferase-expressing T cells are required to control chronic viral infection.

Cox MA, Duncan GS, Lin GHY, Steinberg BE, Yu LX, Brenner D, Buckler LN, Elia AJ, Wakeham AC, Nieman B, Dominguez-Brauer C, Elford AR, Gill KT, Kubli SP, Haight J, Berger T, Ohashi PS, Tracey KJ, Olofsson PS, Mak TW.

Science. 2019 Feb 8;363(6427):639-644. doi: 10.1126/science.aau9072.

PMID:
30733420
4.

AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer.

Kubli SP, Bassi C, Roux C, Wakeham A, Göbl C, Zhou W, Jafari SM, Snow B, Jones L, Palomero L, Thu KL, Cassetta L, Soong D, Berger T, Ramachandran P, Baniasadi SP, Duncan G, Lindzen M, Yarden Y, Herranz C, Lazaro C, Chu MF, Haight J, Tinto P, Silvester J, Cescon DW, Petit A, Pettersson S, Pollard JW, Mak TW, Pujana MA, Cappello P, Gorrini C.

Proc Natl Acad Sci U S A. 2019 Feb 7. pii: 201815126. doi: 10.1073/pnas.1815126116. [Epub ahead of print]

PMID:
30733286
5.

Revisiting the Relationship Between Internal Focus and Balance Control in Young and Older Adults.

Chow VWK, Ellmers TJ, Young WR, Mak TCT, Wong TWL.

Front Neurol. 2019 Jan 9;9:1131. doi: 10.3389/fneur.2018.01131. eCollection 2018.

6.

Luminescent cyclic trinuclear coinage metal complexes with aggregation-induced emission (AIE) performance.

Tian Y, Wang ZY, Zang SQ, Li D, Mak TCW.

Dalton Trans. 2019 Feb 12;48(7):2275-2279. doi: 10.1039/c8dt04898c.

PMID:
30667424
7.

Hippo pathway controls cell adhesion and context-dependent cell competition to influence skin engraftment efficiency.

Nishio M, Miyachi Y, Otani J, Tane S, Omori H, Ueda F, Togashi H, Sasaki T, Mak TW, Nakao K, Fujita Y, Nishina H, Maehama T, Suzuki A.

FASEB J. 2019 Jan 14:fj201802005R. doi: 10.1096/fj.201802005R. [Epub ahead of print]

PMID:
30640535
8.

Adenylyl Cyclase 6 Mediates Inhibition of TNF in the Inflammatory Reflex.

Tarnawski L, Reardon C, Caravaca AS, Rosas-Ballina M, Tusche MW, Drake AR, Hudson LK, Hanes WM, Li JH, Parrish WR, Ojamaa K, Al-Abed Y, Faltys M, Pavlov VA, Andersson U, Chavan SS, Levine YA, Mak TW, Tracey KJ, Olofsson PS.

Front Immunol. 2018 Nov 27;9:2648. doi: 10.3389/fimmu.2018.02648. eCollection 2018.

9.

Parasitic Behavior of Leukemic Cells in Systemic Host Metabolism.

Leca J, Berger T, Mak TW.

Cell Metab. 2018 Dec 4;28(6):811-813. doi: 10.1016/j.cmet.2018.11.011.

PMID:
30517895
10.

Extended theory of planned behaviour for promoting construction waste recycling in Hong Kong.

Mak TMW, Yu IKM, Wang L, Hsu SC, Tsang DCW, Li CN, Yeung TLY, Zhang R, Poon CS.

Waste Manag. 2019 Jan;83:161-170. doi: 10.1016/j.wasman.2018.11.016.

PMID:
30514463
11.

Localisation of Colorectal Polyps by Convolutional Neural Network Features Learnt from White Light and Narrow Band Endoscopic Images of Multiple Databases.

Zheng Y, Zhang R, Yu R, Jiang Y, Mak TWC, Wong SH, Lau JYW, Poon CCY.

Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:4142-4145. doi: 10.1109/EMBC.2018.8513337.

PMID:
30441267
12.

The Antiarrhythmic Drug, Dronedarone, Demonstrates Cytotoxic Effects in Breast Cancer Independent of Thyroid Hormone Receptor Alpha 1 (THRα1) Antagonism.

Elliott MJ, Jerzak KJ, Cockburn JG, Safikhani Z, Gwynne WD, Hassell JA, Bane A, Silvester J, Thu KL, Haibe-Kains B, Mak TW, Cescon DW.

Sci Rep. 2018 Nov 8;8(1):16562. doi: 10.1038/s41598-018-34348-0.

13.

TAp73-induced phosphofructokinase-1 transcription promotes the Warburg effect and enhances cell proliferation.

Li L, Li L, Li W, Chen T, Bin Zou, Zhao L, Wang H, Wang X, Xu L, Liu X, Wang D, Li B, Mak TW, Du W, Yang X, Jiang P.

Nat Commun. 2018 Nov 8;9(1):4683. doi: 10.1038/s41467-018-07127-8.

14.

p53 mutants cooperate with HIF-1 in transcriptional regulation of extracellular matrix components to promote tumor progression.

Amelio I, Mancini M, Petrova V, Cairns RA, Vikhreva P, Nicolai S, Marini A, Antonov AA, Le Quesne J, Baena Acevedo JD, Dudek K, Sozzi G, Pastorino U, Knight RA, Mak TW, Melino G.

Proc Natl Acad Sci U S A. 2018 Nov 13;115(46):E10869-E10878. doi: 10.1073/pnas.1808314115. Epub 2018 Oct 31.

15.

Reply to Oegema et al.: CFI-400945 and Polo-like kinase 4 inhibition.

Kawakami M, Mustachio LM, Zheng L, Chen Y, Rodriguez-Canales J, Mino B, Kurie JM, Roszik J, Villalobos PA, Thu KL, Silvester J, Cescon DW, Wistuba II, Mak TW, Liu X, Dmitrovsky E.

Proc Natl Acad Sci U S A. 2018 Nov 13;115(46):E10810-E10811. doi: 10.1073/pnas.1813967115. Epub 2018 Oct 30. No abstract available.

PMID:
30377273
16.

A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening.

Yan HHN, Siu HC, Law S, Ho SL, Yue SSK, Tsui WY, Chan D, Chan AS, Ma S, Lam KO, Bartfeld S, Man AHY, Lee BCH, Chan ASY, Wong JWH, Cheng PSW, Chan AKW, Zhang J, Shi J, Fan X, Kwong DLW, Mak TW, Yuen ST, Clevers H, Leung SY.

Cell Stem Cell. 2018 Dec 6;23(6):882-897.e11. doi: 10.1016/j.stem.2018.09.016. Epub 2018 Oct 18.

PMID:
30344100
17.

Overview of wastewater treatment methods with special focus on biopolymer chitin-chitosan.

Sarode S, Upadhyay P, Khosa MA, Mak T, Shakir A, Song S, Ullah A.

Int J Biol Macromol. 2019 Jan;121:1086-1100. doi: 10.1016/j.ijbiomac.2018.10.089. Epub 2018 Oct 18. Review.

PMID:
30342936
18.

Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicine.

Carbone M, Amelio I, Affar EB, Brugarolas J, Cannon-Albright LA, Cantley LC, Cavenee WK, Chen Z, Croce CM, Andrea A, Gandara D, Giorgi C, Jia W, Lan Q, Mak TW, Manley JL, Mikoshiba K, Onuchic JN, Pass HI, Pinton P, Prives C, Rothman N, Sebti SM, Turkson J, Wu X, Yang H, Yu H, Melino G.

Cell Death Differ. 2018 Nov;25(11):1885-1904. doi: 10.1038/s41418-018-0213-5. Epub 2018 Oct 15.

PMID:
30323273
19.

Gait Stability in Older Adults during Level-ground Walking: The Attentional Focus Approach.

Mak TCT, Young WR, Chan DCL, Wong TWL.

J Gerontol B Psychol Sci Soc Sci. 2018 Oct 8. doi: 10.1093/geronb/gby115. [Epub ahead of print]

PMID:
30299520
20.

Photoluminescence modulation of an atomically precise silver(i)-thiolate cluster via site-specific surface engineering.

Li YL, Zhang WM, Wang J, Tian Y, Wang ZY, Du CX, Zang SQ, Mak TCW.

Dalton Trans. 2018 Oct 30;47(42):14884-14888. doi: 10.1039/c8dt03165g.

PMID:
30284574
21.

Gelsemium poisoning mediated by the non-toxic plant Cassytha filiformis parasitizing Gelsemium elegans.

Cheung WL, Law CY, Lee HCH, Tang CO, Lam YH, Ng SW, Chan SS, Chow TC, Pang KS, Mak TWL.

Toxicon. 2018 Nov;154:42-49. doi: 10.1016/j.toxicon.2018.09.009. Epub 2018 Sep 28.

PMID:
30273705
22.

Loss of the adipokine lipocalin-2 impairs satellite cell activation and skeletal muscle regeneration.

Rebalka IA, Monaco CMF, Varah NE, Berger T, D'souza DM, Zhou S, Mak TW, Hawke TJ.

Am J Physiol Cell Physiol. 2018 Nov 1;315(5):C714-C721. doi: 10.1152/ajpcell.00195.2017. Epub 2018 Sep 26.

PMID:
30257107
23.

Trans-Ethnic Polygenic Analysis Supports Genetic Overlaps of Lumbar Disc Degeneration With Height, Body Mass Index, and Bone Mineral Density.

Zhou X, Cheung CL, Karasugi T, Karppinen J, Samartzis D, Hsu YH, Mak TS, Song YQ, Chiba K, Kawaguchi Y, Li Y, Chan D, Cheung KM, Ikegawa S, Cheah KS, Sham PC.

Front Genet. 2018 Aug 3;9:267. doi: 10.3389/fgene.2018.00267. eCollection 2018.

24.

A powerful conditional gene-based association approach implicated functionally important genes for schizophrenia.

Li M, Jiang L, Mak TSH, Kwan JSH, Xue C, Chen P, Leung HC, Cui L, Li T, Sham PC.

Bioinformatics. 2019 Feb 15;35(4):628-635. doi: 10.1093/bioinformatics/bty682.

PMID:
30101339
25.

Global metabolomic responses in urine from atm deficient mice in response to LD50/30 gamma irradiation doses.

Laiakis EC, Mak TD, Strawn SJ, Wang YW, Moon BH, Ake P, Fornace AJ Jr.

Environ Mol Mutagen. 2018 Aug;59(7):576-585. doi: 10.1002/em.22202. Epub 2018 Aug 10.

PMID:
30095186
26.

Cluster of acute poisonings associated with an emerging ketamine analogue, 2-oxo-PCE.

Tang MHY, Chong YK, Chan CY, Ching CK, Lai CK, Li YK, Mak TWL.

Forensic Sci Int. 2018 Sep;290:238-243. doi: 10.1016/j.forsciint.2018.07.014. Epub 2018 Jul 24.

PMID:
30081327
27.

Targeting the cell cycle in breast cancer: towards the next phase.

Thu KL, Soria-Bretones I, Mak TW, Cescon DW.

Cell Cycle. 2018;17(15):1871-1885. doi: 10.1080/15384101.2018.1502567. Epub 2018 Sep 11.

PMID:
30078354
28.

RASAL2 promotes tumor progression through LATS2/YAP1 axis of hippo signaling pathway in colorectal cancer.

Pan Y, Tong JHM, Lung RWM, Kang W, Kwan JSH, Chak WP, Tin KY, Chung LY, Wu F, Ng SSM, Mak TWC, Yu J, Lo KW, Chan AWH, To KF.

Mol Cancer. 2018 Jul 23;17(1):102. doi: 10.1186/s12943-018-0853-6.

29.

Coverage and diagnostic yield of Whole Exome Sequencing for the Evaluation of Cases with Dilated and Hypertrophic Cardiomyopathy.

Mak TSH, Lee YK, Tang CS, Hai JSH, Ran X, Sham PC, Tse HF.

Sci Rep. 2018 Jul 18;8(1):10846. doi: 10.1038/s41598-018-29263-3.

30.

Creating a Mass Spectral Reference Library for Oligosaccharides in Human Milk.

Remoroza CA, Mak TD, De Leoz MLA, Mirokhin YA, Stein SE.

Anal Chem. 2018 Aug 7;90(15):8977-8988. doi: 10.1021/acs.analchem.8b01176. Epub 2018 Jul 17.

PMID:
29969231
31.

Granulin epithelin precursor promotes colorectal carcinogenesis by activating MARK/ERK pathway.

Pan Y, Cheung ST, Tong JHM, Tin KY, Kang W, Lung RWM, Wu F, Li H, Ng SSM, Mak TWC, To KF, Chan AWH.

J Transl Med. 2018 Jun 4;16(1):150. doi: 10.1186/s12967-018-1530-7.

32.

Tandem Silver Cluster Isomerism and Mixed Linkers to Modulate the Photoluminescence of Cluster-Assembled Materials.

Huang RW, Dong XY, Yan BJ, Du XS, Wei DH, Zang SQ, Mak TCW.

Angew Chem Int Ed Engl. 2018 Jul 9;57(28):8560-8566. doi: 10.1002/anie.201804059. Epub 2018 Jun 14.

PMID:
29797756
33.

Fighting Fire with Fire in Cancer.

Berger T, Saunders ME, Mak TW.

In: Nakao K, Minato N, Uemoto S, editors. Innovative Medicine: Basic Research and Development [Internet]. Tokyo: Springer; 2015.

34.

Transforming growth factor-β signalling in renal fibrosis: from Smads to non-coding RNAs.

Tang PM, Zhang YY, Mak TS, Tang PC, Huang XR, Lan HY.

J Physiol. 2018 Aug;596(16):3493-3503. doi: 10.1113/JP274492. Epub 2018 Jun 28.

PMID:
29781524
35.

Blood-induced bone loss in murine hemophilic arthropathy is prevented by blocking the iRhom2/ADAM17/TNF-α pathway.

Haxaire C, Hakobyan N, Pannellini T, Carballo C, McIlwain D, Mak TW, Rodeo S, Acharya S, Li D, Szymonifka J, Song X, Monette S, Srivastava A, Salmon JE, Blobel CP.

Blood. 2018 Sep 6;132(10):1064-1074. doi: 10.1182/blood-2017-12-820571. Epub 2018 May 18.

PMID:
29776906
36.

Immunization Elicits Antigen-Specific Antibody Sequestration in Dorsal Root Ganglia Sensory Neurons.

Gunasekaran M, Chatterjee PK, Shih A, Imperato GH, Addorisio M, Kumar G, Lee A, Graf JF, Meyer D, Marino M, Puleo C, Ashe J, Cox MA, Mak TW, Bouton C, Sherry B, Diamond B, Andersson U, Coleman TR, Metz CN, Tracey KJ, Chavan SS.

Front Immunol. 2018 Apr 16;9:638. doi: 10.3389/fimmu.2018.00638. eCollection 2018.

37.

Self-Assembly of a Stable Silver Thiolate Nanocluster Encapsulating a Lacunary Keggin Phosphotungstate Anion.

Yan BJ, Du XS, Huang RW, Yang JS, Wang ZY, Zang SQ, Mak TCW.

Inorg Chem. 2018 May 7;57(9):4828-4832. doi: 10.1021/acs.inorgchem.8b00702. Epub 2018 Apr 26.

PMID:
29697246
38.

Retrospective Study of the Characteristics of Anticoagulant-Type Rodenticide Poisoning in Hong Kong.

Ng WY, Ching CK, Chong YK, Ng SW, Cheung WL, Mak TWL.

J Med Toxicol. 2018 Sep;14(3):218-228. doi: 10.1007/s13181-018-0660-x. Epub 2018 Apr 23.

PMID:
29687220
39.

Co-inhibitory Molecule B7 Superfamily Member 1 Expressed by Tumor-Infiltrating Myeloid Cells Induces Dysfunction of Anti-tumor CD8+ T Cells.

Li J, Lee Y, Li Y, Jiang Y, Lu H, Zang W, Zhao X, Liu L, Chen Y, Tan H, Yang Z, Zhang MQ, Mak TW, Ni L, Dong C.

Immunity. 2018 Apr 17;48(4):773-786.e5. doi: 10.1016/j.immuni.2018.03.018. Epub 2018 Apr 3.

PMID:
29625896
40.

Evaluation of three rapid oral fluid test devices on the screening of multiple drugs of abuse including ketamine.

Tang MHY, Ching CK, Poon S, Chan SSS, Ng WY, Lam M, Wong CK, Pao R, Lau A, Mak TWL.

Forensic Sci Int. 2018 May;286:113-120. doi: 10.1016/j.forsciint.2018.03.004. Epub 2018 Mar 12.

PMID:
29574346
41.

Loss of Mob1a/b in mice results in chondrodysplasia due to YAP1/TAZ-TEAD-dependent repression of SOX9.

Goto H, Nishio M, To Y, Oishi T, Miyachi Y, Maehama T, Nishina H, Akiyama H, Mak TW, Makii Y, Saito T, Yasoda A, Tsumaki N, Suzuki A.

Development. 2018 Mar 16;145(6). pii: dev159244. doi: 10.1242/dev.159244.

42.

Halogen-Bond-Mediated Assembly of a Single-Component Supramolecular Triangle and an Enantiomeric Pair of Double Helices from 2-(Iodoethynyl)pyridine Derivatives.

Ng CF, Chow HF, Mak TCW.

Angew Chem Int Ed Engl. 2018 Apr 23;57(18):4986-4990. doi: 10.1002/anie.201800469. Epub 2018 Mar 24.

PMID:
29498164
43.

High-Nuclearity Heterometallic tert-Butylethynide Clusters Assembled with tert-Butylphosphonate.

Duan GX, Xie YP, Jin JL, Bao LP, Lu X, Mak TCW.

Chemistry. 2018 May 7;24(26):6762-6768. doi: 10.1002/chem.201705906. Epub 2018 Mar 22.

PMID:
29473225
44.

A Complex Role for Lipocalin 2 in Bone Metabolism: Global Ablation in Mice Induces Osteopenia Caused by an Altered Energy Metabolism.

Capulli M, Ponzetti M, Maurizi A, Gemini-Piperni S, Berger T, Mak TW, Teti A, Rucci N.

J Bone Miner Res. 2018 Jun;33(6):1141-1153. doi: 10.1002/jbmr.3406. Epub 2018 Mar 24.

PMID:
29444358
45.

Fragment-Based Screening of a Natural Product Library against 62 Potential Malaria Drug Targets Employing Native Mass Spectrometry.

Vu H, Pedro L, Mak T, McCormick B, Rowley J, Liu M, Di Capua A, Williams-Noonan B, Pham NB, Pouwer R, Nguyen B, Andrews KT, Skinner-Adams T, Kim J, Hol WGJ, Hui R, Crowther GJ, Van Voorhis WC, Quinn RJ.

ACS Infect Dis. 2018 Apr 13;4(4):431-444. doi: 10.1021/acsinfecdis.7b00197. Epub 2018 Mar 3.

46.

Polo-like kinase 4 inhibition produces polyploidy and apoptotic death of lung cancers.

Kawakami M, Mustachio LM, Zheng L, Chen Y, Rodriguez-Canales J, Mino B, Kurie JM, Roszik J, Villalobos PA, Thu KL, Silvester J, Cescon DW, Wistuba II, Mak TW, Liu X, Dmitrovsky E.

Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):1913-1918. doi: 10.1073/pnas.1719760115. Epub 2018 Feb 6.

47.

Disruption of the anaphase-promoting complex confers resistance to TTK inhibitors in triple-negative breast cancer.

Thu KL, Silvester J, Elliott MJ, Ba-Alawi W, Duncan MH, Elia AC, Mer AS, Smirnov P, Safikhani Z, Haibe-Kains B, Mak TW, Cescon DW.

Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):E1570-E1577. doi: 10.1073/pnas.1719577115. Epub 2018 Jan 29.

48.

Holo-lipocalin-2-derived siderophores increase mitochondrial ROS and impair oxidative phosphorylation in rat cardiomyocytes.

Song E, Ramos SV, Huang X, Liu Y, Botta A, Sung HK, Turnbull PC, Wheeler MB, Berger T, Wilson DJ, Perry CGR, Mak TW, Sweeney G.

Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):1576-1581. doi: 10.1073/pnas.1720570115. Epub 2018 Jan 29.

49.

iRhom2 promotes lupus nephritis through TNF-α and EGFR signaling.

Qing X, Chinenov Y, Redecha P, Madaio M, Roelofs JJ, Farber G, Issuree PD, Donlin L, Mcllwain DR, Mak TW, Blobel CP, Salmon JE.

J Clin Invest. 2018 Apr 2;128(4):1397-1412. doi: 10.1172/JCI97650. Epub 2018 Mar 5.

50.

Author Correction: Gene isoforms as expression-based biomarkers predictive of drug response in vitro.

Safikhani Z, Smirnov P, Thu KL, Silvester J, El-Hachem N, Quevedo R, Lupien M, Mak TW, Cescon D, Haibe-Kains B.

Nat Commun. 2018 Jan 9;9(1):166. doi: 10.1038/s41467-017-02136-5.

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