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Beyond Neurotransmission: Acetylcholine in Immunity and Inflammation.

Cox MA, Bassi C, Saunders ME, Nechanitzky R, Morgado-Palacin I, Zheng C, Mak TW.

J Intern Med. 2019 Nov 11. doi: 10.1111/joim.13006. [Epub ahead of print] Review.


iRhom2 inhibits bile duct obstruction-induced liver fibrosis.

Sundaram B, Behnke K, Belancic A, Al-Salihi MA, Thabet Y, Polz R, Pellegrino R, Zhuang Y, Shinde PV, Xu HC, Vasilevska J, Longerich T, Herebian D, Mayatepek E, Bock HH, May P, Kordes C, Aghaeepour N, Mak TW, Keitel V, Häussinger D, Scheller J, Pandyra AA, Lang KS, Lang PA.

Sci Signal. 2019 Oct 29;12(605). pii: eaax1194. doi: 10.1126/scisignal.aax1194.


The role of attentional focus on walking efficiency among older fallers and non-fallers.

Mak TCT, Young WR, Lam WK, Tse ACY, Wong TWL.

Age Ageing. 2019 Nov 1;48(6):811-816. doi: 10.1093/ageing/afz113.


Cu14 Cluster with Partial Cu(0) Character: Difference in Electronic Structure from Isostructural Silver Analog.

Li YL, Wang J, Luo P, Ma XH, Dong XY, Wang ZY, Du CX, Zang SQ, Mak TCW.

Adv Sci (Weinh). 2019 Jul 26;6(18):1900833. doi: 10.1002/advs.201900833. eCollection 2019 Sep 18.


Neutrophils homing into the retina trigger pathology in early age-related macular degeneration.

Ghosh S, Padmanabhan A, Vaidya T, Watson AM, Bhutto IA, Hose S, Shang P, Stepicheva N, Yazdankhah M, Weiss J, Das M, Gopikrishna S, Aishwarya, Yadav N, Berger T, Mak TW, Xia S, Qian J, Lutty GA, Jayagopal A, Zigler JS Jr, Sethu S, Handa JT, Watkins SC, Ghosh A, Sinha D.

Commun Biol. 2019 Sep 20;2:348. doi: 10.1038/s42003-019-0588-y. eCollection 2019.


Diet Diversity and Micronutrient Adequacy among Filipino School-Age Children.

Mak TN, Angeles-Agdeppa I, Lenighan YM, Capanzana MV, Montoliu I.

Nutrients. 2019 Sep 12;11(9). pii: E2197. doi: 10.3390/nu11092197.


Author Correction: Fcmr regulates mononuclear phagocyte control of anti-tumor immunity.

Kubli SP, Vornholz L, Duncan G, Zhou W, Ramachandran P, Fortin J, Cox M, Han S, Nechanitzky R, Nechanitzky D, Snow BE, Jones L, Li WY, Haight J, Wakeham A, Bray MR, Mak TW.

Nat Commun. 2019 Sep 3;10(1):4069. doi: 10.1038/s41467-019-12106-8.


Emerging roles of HECT-type E3 ubiquitin ligases in autophagy regulation.

Melino G, Cecconi F, Pelicci PG, Mak TW, Bernassola F.

Mol Oncol. 2019 Oct;13(10):2033-2048. doi: 10.1002/1878-0261.12567. Epub 2019 Sep 5. Review.


Acupuncture for overactive bladder in adults: a systematic review and meta-analysis.

Mak TC, Cho WC, Chen HY.

Acupunct Med. 2019 Aug 21:acupmed2017011528. doi: 10.1136/acupmed-2017-011528. [Epub ahead of print]


Porphyrinic Silver Cluster Assembled Material for Simultaneous Capture and Photocatalysis of Mustard-Gas Simulant.

Cao M, Pang R, Wang QY, Han Z, Wang ZY, Dong XY, Li SF, Zang SQ, Mak TCW.

J Am Chem Soc. 2019 Sep 18;141(37):14505-14509. doi: 10.1021/jacs.9b05952. Epub 2019 Aug 20.


Lysergic acid diethylamide-associated intoxication in Hong Kong: a case series.

Li C, Tang MHY, Chong YK, Chan TYC, Mak TWL.

Hong Kong Med J. 2019 Aug;25(4):323-325. doi: 10.12809/hkmj197942. No abstract available.


Macrophages in Renal Fibrosis.

Meng XM, Mak TS, Lan HY.

Adv Exp Med Biol. 2019;1165:285-303. doi: 10.1007/978-981-13-8871-2_13. Review.


Tyrosine Threonine Kinase Inhibition Eliminates Lung Cancers by Augmenting Apoptosis and Polyploidy.

Zheng L, Chen Z, Kawakami M, Chen Y, Roszik J, Mustachio LM, Kurie JM, Villalobos P, Lu W, Behrens C, Mino B, Solis LM, Silvester J, Thu KL, Cescon DW, Rodriguez-Canales J, Wistuba II, Mak TW, Liu X, Dmitrovsky E.

Mol Cancer Ther. 2019 Oct;18(10):1775-1786. doi: 10.1158/1535-7163.MCT-18-0864. Epub 2019 Jul 29.


Safety and tolerability of CFI-400945, a first-in-class, selective PLK4 inhibitor in advanced solid tumours: a phase 1 dose-escalation trial.

Veitch ZW, Cescon DW, Denny T, Yonemoto LM, Fletcher G, Brokx R, Sampson P, Li SW, Pugh TJ, Bruce J, Bray MR, Slamon DJ, Mak TW, Wainberg ZA, Bedard PL.

Br J Cancer. 2019 Aug;121(4):318-324. doi: 10.1038/s41416-019-0517-3. Epub 2019 Jul 15.


The 100 most cited manuscripts in coronary artery bypass grafting.

Chan J, Mak TLA, Chu TSM, Hui TLY, Kwan LYA.

J Card Surg. 2019 Sep;34(9):782-787. doi: 10.1111/jocs.14138. Epub 2019 Jul 3.


Fcmr regulates mononuclear phagocyte control of anti-tumor immunity.

Kubli SP, Vornholz L, Duncan G, Zhou W, Ramachandran P, Fortin J, Cox M, Han S, Nechanitzky R, Nechanitzky D, Snow BE, Jones L, Li WY, Haight J, Wakeham A, Bray MR, Mak TW.

Nat Commun. 2019 Jun 18;10(1):2678. doi: 10.1038/s41467-019-10619-w. Erratum in: Nat Commun. 2019 Sep 3;10(1):4069.


Role of Hepatic Glucocorticoid Receptor in Metabolism in Models of 5αR1 Deficiency in Male Mice.

Mak TCS, Livingstone DEW, Nixon M, Walker BR, Andrew R.

Endocrinology. 2019 Sep 1;160(9):2061-2073. doi: 10.1210/en.2019-00236.


Evaluating the effectiveness of the influenza vaccine during respiratory outbreaks in Singapore's long term care facilities, 2017.

Ng Y, Nandar K, Chua LAV, Mak TM, Foo K, Muhammad IR, Low CKK, Ma S, Ooi SP, Lin RTP, James L, Lee VJM.

Vaccine. 2019 Jun 27;37(29):3925-3931. doi: 10.1016/j.vaccine.2019.03.054. Epub 2019 May 31.


MOB1 regulates thymocyte egress and T-cell survival in mice in a YAP1-independent manner.

Kato W, Nishio M, To Y, Togashi H, Mak TW, Takada H, Ohga S, Maehama T, Suzuki A.

Genes Cells. 2019 Jul;24(7):485-495. doi: 10.1111/gtc.12704. Epub 2019 May 24.


Role for polo-like kinase 4 in mediation of cytokinesis.

Press MF, Xie B, Davenport S, Zhou Y, Guzman R, Nolan GP, O'Brien N, Palazzolo M, Mak TW, Brugge JS, Slamon DJ.

Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11309-11318. doi: 10.1073/pnas.1818820116. Epub 2019 May 16.


Dendritic cells are crucial for cardiovascular remodeling and modulate neutrophil gelatinase-associated lipocalin expression upon mineralocorticoid receptor activation.

Araos P, Prado C, Lozano M, Figueroa S, Espinoza A, Berger T, Mak TW, Jaisser F, Pacheco R, Michea L, Amador CA.

J Hypertens. 2019 Jul;37(7):1482-1492. doi: 10.1097/HJH.0000000000002067.


Ketamine analogues multiplying in Hong Kong.

Li C, Lai CK, Tang MHY, Chan CCK, Chong YK, Mak TWL.

Hong Kong Med J. 2019 Apr;25(2):169. doi: 10.12809/hkmj197863. No abstract available.


Poisoning by toxic plants in Hong Kong: a 15-year review.

Ng WY, Hung LY, Lam YH, Chan SS, Pang KS, Chong YK, Ching CK, Mak TWL.

Hong Kong Med J. 2019 Apr;25(2):102-112. doi: 10.12809/hkmj187745. Epub 2019 Apr 10.


Development of an HPLC-based guanosine monophosphate kinase assay and application to Plasmodium vivax guanylate kinase.

Pedro L, Cross M, Hofmann A, Mak T, Quinn RJ.

Anal Biochem. 2019 Jun 15;575:63-69. doi: 10.1016/j.ab.2019.03.022. Epub 2019 Mar 31.


YAP/Yorkie in the germline modulates the age-related decline of germline stem cells and niche cells.

Francis D, Chanana B, Fernandez B, Gordon B, Mak T, Palacios IM.

PLoS One. 2019 Apr 3;14(4):e0213327. doi: 10.1371/journal.pone.0213327. eCollection 2019.


Differential age-specific distribution of influenza virus types and subtypes in tropical Singapore, 2011 to 2017.

Ang LW, Cui L, Mak TM, Ng Y, Leo YS, Lee VJM, Lin RT.

J Med Virol. 2019 Aug;91(8):1415-1422. doi: 10.1002/jmv.25473. Epub 2019 Apr 9.


HDAC2 Regulates Site-Specific Acetylation of MDM2 and Its Ubiquitination Signaling in Tumor Suppression.

Patel N, Wang J, Shiozawa K, Jones KB, Zhang Y, Prokop JW, Davenport GG, Nihira NT, Hao Z, Wong D, Brandsmeier L, Meadows SK, Sampaio AV, Werff RV, Endo M, Capecchi MR, McNagny KM, Mak TW, Nielsen TO, Underhill TM, Myers RM, Kondo T, Su L.

iScience. 2019 Mar 29;13:43-54. doi: 10.1016/j.isci.2019.02.008. Epub 2019 Feb 15.


Reactive oxygen species modulate macrophage immunosuppressive phenotype through the up-regulation of PD-L1.

Roux C, Jafari SM, Shinde R, Duncan G, Cescon DW, Silvester J, Chu MF, Hodgson K, Berger T, Wakeham A, Palomero L, Garcia-Valero M, Pujana MA, Mak TW, McGaha TL, Cappello P, Gorrini C.

Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4326-4335. doi: 10.1073/pnas.1819473116. Epub 2019 Feb 15.


Glutathione Metabolism: An Achilles' Heel of ARID1A-Deficient Tumors.

Gorrini C, Mak TW.

Cancer Cell. 2019 Feb 11;35(2):161-163. doi: 10.1016/j.ccell.2019.01.017.


Choline acetyltransferase-expressing T cells are required to control chronic viral infection.

Cox MA, Duncan GS, Lin GHY, Steinberg BE, Yu LX, Brenner D, Buckler LN, Elia AJ, Wakeham AC, Nieman B, Dominguez-Brauer C, Elford AR, Gill KT, Kubli SP, Haight J, Berger T, Ohashi PS, Tracey KJ, Olofsson PS, Mak TW.

Science. 2019 Feb 8;363(6427):639-644. doi: 10.1126/science.aau9072.


AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer.

Kubli SP, Bassi C, Roux C, Wakeham A, Göbl C, Zhou W, Jafari SM, Snow B, Jones L, Palomero L, Thu KL, Cassetta L, Soong D, Berger T, Ramachandran P, Baniasadi SP, Duncan G, Lindzen M, Yarden Y, Herranz C, Lazaro C, Chu MF, Haight J, Tinto P, Silvester J, Cescon DW, Petit A, Pettersson S, Pollard JW, Mak TW, Pujana MA, Cappello P, Gorrini C.

Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3604-3613. doi: 10.1073/pnas.1815126116. Epub 2019 Feb 7.


Revisiting the Relationship Between Internal Focus and Balance Control in Young and Older Adults.

Chow VWK, Ellmers TJ, Young WR, Mak TCT, Wong TWL.

Front Neurol. 2019 Jan 9;9:1131. doi: 10.3389/fneur.2018.01131. eCollection 2018.


Luminescent cyclic trinuclear coinage metal complexes with aggregation-induced emission (AIE) performance.

Tian Y, Wang ZY, Zang SQ, Li D, Mak TCW.

Dalton Trans. 2019 Feb 12;48(7):2275-2279. doi: 10.1039/c8dt04898c.


Hippo pathway controls cell adhesion and context-dependent cell competition to influence skin engraftment efficiency.

Nishio M, Miyachi Y, Otani J, Tane S, Omori H, Ueda F, Togashi H, Sasaki T, Mak TW, Nakao K, Fujita Y, Nishina H, Maehama T, Suzuki A.

FASEB J. 2019 Apr;33(4):5548-5560. doi: 10.1096/fj.201802005R. Epub 2019 Jan 14.


Adenylyl Cyclase 6 Mediates Inhibition of TNF in the Inflammatory Reflex.

Tarnawski L, Reardon C, Caravaca AS, Rosas-Ballina M, Tusche MW, Drake AR, Hudson LK, Hanes WM, Li JH, Parrish WR, Ojamaa K, Al-Abed Y, Faltys M, Pavlov VA, Andersson U, Chavan SS, Levine YA, Mak TW, Tracey KJ, Olofsson PS.

Front Immunol. 2018 Nov 27;9:2648. doi: 10.3389/fimmu.2018.02648. eCollection 2018.


Parasitic Behavior of Leukemic Cells in Systemic Host Metabolism.

Leca J, Berger T, Mak TW.

Cell Metab. 2018 Dec 4;28(6):811-813. doi: 10.1016/j.cmet.2018.11.011.


Extended theory of planned behaviour for promoting construction waste recycling in Hong Kong.

Mak TMW, Yu IKM, Wang L, Hsu SC, Tsang DCW, Li CN, Yeung TLY, Zhang R, Poon CS.

Waste Manag. 2019 Jan;83:161-170. doi: 10.1016/j.wasman.2018.11.016.


Localisation of Colorectal Polyps by Convolutional Neural Network Features Learnt from White Light and Narrow Band Endoscopic Images of Multiple Databases.

Zheng Y, Zhang R, Yu R, Jiang Y, Mak TWC, Wong SH, Lau JYW, Poon CCY.

Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:4142-4145. doi: 10.1109/EMBC.2018.8513337.


The Antiarrhythmic Drug, Dronedarone, Demonstrates Cytotoxic Effects in Breast Cancer Independent of Thyroid Hormone Receptor Alpha 1 (THRα1) Antagonism.

Elliott MJ, Jerzak KJ, Cockburn JG, Safikhani Z, Gwynne WD, Hassell JA, Bane A, Silvester J, Thu KL, Haibe-Kains B, Mak TW, Cescon DW.

Sci Rep. 2018 Nov 8;8(1):16562. doi: 10.1038/s41598-018-34348-0.


TAp73-induced phosphofructokinase-1 transcription promotes the Warburg effect and enhances cell proliferation.

Li L, Li L, Li W, Chen T, Bin Zou, Zhao L, Wang H, Wang X, Xu L, Liu X, Wang D, Li B, Mak TW, Du W, Yang X, Jiang P.

Nat Commun. 2018 Nov 8;9(1):4683. doi: 10.1038/s41467-018-07127-8.


p53 mutants cooperate with HIF-1 in transcriptional regulation of extracellular matrix components to promote tumor progression.

Amelio I, Mancini M, Petrova V, Cairns RA, Vikhreva P, Nicolai S, Marini A, Antonov AA, Le Quesne J, Baena Acevedo JD, Dudek K, Sozzi G, Pastorino U, Knight RA, Mak TW, Melino G.

Proc Natl Acad Sci U S A. 2018 Nov 13;115(46):E10869-E10878. doi: 10.1073/pnas.1808314115. Epub 2018 Oct 31.


Reply to Oegema et al.: CFI-400945 and Polo-like kinase 4 inhibition.

Kawakami M, Mustachio LM, Zheng L, Chen Y, Rodriguez-Canales J, Mino B, Kurie JM, Roszik J, Villalobos PA, Thu KL, Silvester J, Cescon DW, Wistuba II, Mak TW, Liu X, Dmitrovsky E.

Proc Natl Acad Sci U S A. 2018 Nov 13;115(46):E10810-E10811. doi: 10.1073/pnas.1813967115. Epub 2018 Oct 30. No abstract available.


A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening.

Yan HHN, Siu HC, Law S, Ho SL, Yue SSK, Tsui WY, Chan D, Chan AS, Ma S, Lam KO, Bartfeld S, Man AHY, Lee BCH, Chan ASY, Wong JWH, Cheng PSW, Chan AKW, Zhang J, Shi J, Fan X, Kwong DLW, Mak TW, Yuen ST, Clevers H, Leung SY.

Cell Stem Cell. 2018 Dec 6;23(6):882-897.e11. doi: 10.1016/j.stem.2018.09.016. Epub 2018 Oct 18.


Overview of wastewater treatment methods with special focus on biopolymer chitin-chitosan.

Sarode S, Upadhyay P, Khosa MA, Mak T, Shakir A, Song S, Ullah A.

Int J Biol Macromol. 2019 Jan;121:1086-1100. doi: 10.1016/j.ijbiomac.2018.10.089. Epub 2018 Oct 18. Review.


Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicine.

Carbone M, Amelio I, Affar EB, Brugarolas J, Cannon-Albright LA, Cantley LC, Cavenee WK, Chen Z, Croce CM, Andrea A, Gandara D, Giorgi C, Jia W, Lan Q, Mak TW, Manley JL, Mikoshiba K, Onuchic JN, Pass HI, Pinton P, Prives C, Rothman N, Sebti SM, Turkson J, Wu X, Yang H, Yu H, Melino G.

Cell Death Differ. 2018 Nov;25(11):1885-1904. doi: 10.1038/s41418-018-0213-5. Epub 2018 Oct 15. Review.


Gait Stability in Older Adults during Level-ground Walking: The Attentional Focus Approach.

Mak TCT, Young WR, Chan DCL, Wong TWL.

J Gerontol B Psychol Sci Soc Sci. 2018 Oct 8. doi: 10.1093/geronb/gby115. [Epub ahead of print]


Photoluminescence modulation of an atomically precise silver(i)-thiolate cluster via site-specific surface engineering.

Li YL, Zhang WM, Wang J, Tian Y, Wang ZY, Du CX, Zang SQ, Mak TCW.

Dalton Trans. 2018 Oct 30;47(42):14884-14888. doi: 10.1039/c8dt03165g.


Gelsemium poisoning mediated by the non-toxic plant Cassytha filiformis parasitizing Gelsemium elegans.

Cheung WL, Law CY, Lee HCH, Tang CO, Lam YH, Ng SW, Chan SS, Chow TC, Pang KS, Mak TWL.

Toxicon. 2018 Nov;154:42-49. doi: 10.1016/j.toxicon.2018.09.009. Epub 2018 Sep 28.


Loss of the adipokine lipocalin-2 impairs satellite cell activation and skeletal muscle regeneration.

Rebalka IA, Monaco CMF, Varah NE, Berger T, D'souza DM, Zhou S, Mak TW, Hawke TJ.

Am J Physiol Cell Physiol. 2018 Nov 1;315(5):C714-C721. doi: 10.1152/ajpcell.00195.2017. Epub 2018 Sep 26.

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