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Items: 1 to 50 of 118

1.

Prevalence of self-medication with antibiotics and associated factors in the community of Asmara, Eritrea: a descriptive cross sectional survey.

Ateshim Y, Bereket B, Major F, Emun Y, Woldai B, Pasha I, Habte E, Russom M.

BMC Public Health. 2019 Jun 10;19(1):726. doi: 10.1186/s12889-019-7020-x.

2.

Apoptotic endothelial cells release small extracellular vesicles loaded with immunostimulatory viral-like RNAs.

Hardy MP, Audemard É, Migneault F, Feghaly A, Brochu S, Gendron P, Boilard É, Major F, Dieudé M, Hébert MJ, Perreault C.

Sci Rep. 2019 May 10;9(1):7203. doi: 10.1038/s41598-019-43591-y.

3.

The sequence features that define efficient and specific hAGO2-dependent miRNA silencing guides.

Yan Y, Acevedo M, Mignacca L, Desjardins P, Scott N, Imane R, Quenneville J, Robitaille J, Feghaly A, Gagnon E, Ferbeyre G, Major F.

Nucleic Acids Res. 2018 Sep 19;46(16):8181-8196. doi: 10.1093/nar/gky546.

4.

RNA-MoIP: prediction of RNA secondary structure and local 3D motifs from sequence data.

Yao J, Reinharz V, Major F, Waldispühl J.

Nucleic Acids Res. 2017 Jul 3;45(W1):W573. doi: 10.1093/nar/gkx575. No abstract available.

5.

RNA-MoIP: prediction of RNA secondary structure and local 3D motifs from sequence data.

Yao J, Reinharz V, Major F, Waldispühl J.

Nucleic Acids Res. 2017 Jul 3;45(W1):W440-W444. doi: 10.1093/nar/gkx429.

6.

RNA-Puzzles Round III: 3D RNA structure prediction of five riboswitches and one ribozyme.

Miao Z, Adamiak RW, Antczak M, Batey RT, Becka AJ, Biesiada M, Boniecki MJ, Bujnicki JM, Chen SJ, Cheng CY, Chou FC, Ferré-D'Amaré AR, Das R, Dawson WK, Ding F, Dokholyan NV, Dunin-Horkawicz S, Geniesse C, Kappel K, Kladwang W, Krokhotin A, Łach GE, Major F, Mann TH, Magnus M, Pachulska-Wieczorek K, Patel DJ, Piccirilli JA, Popenda M, Purzycka KJ, Ren A, Rice GM, Santalucia J Jr, Sarzynska J, Szachniuk M, Tandon A, Trausch JJ, Tian S, Wang J, Weeks KM, Williams B 2nd, Xiao Y, Xu X, Zhang D, Zok T, Westhof E.

RNA. 2017 May;23(5):655-672. doi: 10.1261/rna.060368.116. Epub 2017 Jan 30.

7.

Exploring Alternative RNA Structure Sets Using MC-Flashfold and db2cm.

Dallaire P, Major F.

Methods Mol Biol. 2016;1490:237-51. doi: 10.1007/978-1-4939-6433-8_15.

PMID:
27665603
8.

Structural dynamics control the MicroRNA maturation pathway.

Dallaire P, Tan H, Szulwach K, Ma C, Jin P, Major F.

Nucleic Acids Res. 2016 Nov 16;44(20):9956-9964. Epub 2016 Sep 19.

9.

MiRBooking simulates the stoichiometric mode of action of microRNAs.

Weill N, Lisi V, Scott N, Dallaire P, Pelloux J, Major F.

Nucleic Acids Res. 2015 Aug 18;43(14):6730-8. doi: 10.1093/nar/gkv619. Epub 2015 Jun 18.

10.

RNA-Puzzles Round II: assessment of RNA structure prediction programs applied to three large RNA structures.

Miao Z, Adamiak RW, Blanchet MF, Boniecki M, Bujnicki JM, Chen SJ, Cheng C, Chojnowski G, Chou FC, Cordero P, Cruz JA, Ferré-D'Amaré AR, Das R, Ding F, Dokholyan NV, Dunin-Horkawicz S, Kladwang W, Krokhotin A, Lach G, Magnus M, Major F, Mann TH, Masquida B, Matelska D, Meyer M, Peselis A, Popenda M, Purzycka KJ, Serganov A, Stasiewicz J, Szachniuk M, Tandon A, Tian S, Wang J, Xiao Y, Xu X, Zhang J, Zhao P, Zok T, Westhof E.

RNA. 2015 Jun;21(6):1066-84. doi: 10.1261/rna.049502.114. Epub 2015 Apr 16.

11.

Noncoding regions of C. elegans mRNA undergo selective adenosine to inosine deamination and contain a small number of editing sites per transcript.

Wheeler EC, Washburn MC, Major F, Rusch DB, Hundley HA.

RNA Biol. 2015;12(2):162-74. doi: 10.1080/15476286.2015.1017220.

12.

Computational identification of RNA functional determinants by three-dimensional quantitative structure-activity relationships.

Blanchet MF, St-Onge K, Lisi V, Robitaille J, Hamel S, Major F.

Nucleic Acids Res. 2014;42(17):11261-71. doi: 10.1093/nar/gku816. Epub 2014 Sep 8.

13.

Autism-related deficits via dysregulated eIF4E-dependent translational control.

Gkogkas CG, Khoutorsky A, Ran I, Rampakakis E, Nevarko T, Weatherill DB, Vasuta C, Yee S, Truitt M, Dallaire P, Major F, Lasko P, Ruggero D, Nader K, Lacaille JC, Sonenberg N.

Nature. 2013 Jan 17;493(7432):371-7. doi: 10.1038/nature11628. Epub 2012 Nov 21.

14.

Towards 3D structure prediction of large RNA molecules: an integer programming framework to insert local 3D motifs in RNA secondary structure.

Reinharz V, Major F, Waldispühl J.

Bioinformatics. 2012 Jun 15;28(12):i207-14. doi: 10.1093/bioinformatics/bts226.

15.

Determining RNA three-dimensional structures using low-resolution data.

Parisien M, Major F.

J Struct Biol. 2012 Sep;179(3):252-60. doi: 10.1016/j.jsb.2011.12.024. Epub 2012 Feb 23.

16.

RNA-Puzzles: a CASP-like evaluation of RNA three-dimensional structure prediction.

Cruz JA, Blanchet MF, Boniecki M, Bujnicki JM, Chen SJ, Cao S, Das R, Ding F, Dokholyan NV, Flores SC, Huang L, Lavender CA, Lisi V, Major F, Mikolajczak K, Patel DJ, Philips A, Puton T, Santalucia J, Sijenyi F, Hermann T, Rother K, Rother M, Serganov A, Skorupski M, Soltysinski T, Sripakdeevong P, Tuszynska I, Weeks KM, Waldsich C, Wildauer M, Leontis NB, Westhof E.

RNA. 2012 Apr;18(4):610-25. doi: 10.1261/rna.031054.111. Epub 2012 Feb 23.

17.

Approaches targeting K(V)10.1 open a novel window for cancer diagnosis and therapy.

Pardo LA, Gómez-Varela D, Major F, Sansuk K, Leurs R, Downie BR, Tietze LF, Stühmer W.

Curr Med Chem. 2012;19(5):675-82. Review.

PMID:
22204340
18.

Structural messenger RNA contains cytokeratin polymerization and depolymerization signals.

Kloc M, Dallaire P, Reunov A, Major F.

Cell Tissue Res. 2011 Nov;346(2):209-22. doi: 10.1007/s00441-011-1255-x. Epub 2011 Oct 11.

PMID:
21987223
19.

NMR structure of a 4 x 4 nucleotide RNA internal loop from an R2 retrotransposon: identification of a three purine-purine sheared pair motif and comparison to MC-SYM predictions.

Lerman YV, Kennedy SD, Shankar N, Parisien M, Major F, Turner DH.

RNA. 2011 Sep;17(9):1664-77. doi: 10.1261/rna.2641911. Epub 2011 Jul 21.

20.

RNA G-Quadruplexes in the model plant species Arabidopsis thaliana: prevalence and possible functional roles.

Mullen MA, Olson KJ, Dallaire P, Major F, Assmann SM, Bevilacqua PC.

Nucleic Acids Res. 2010 Dec;38(22):8149-63. doi: 10.1093/nar/gkq804. Epub 2010 Sep 21.

21.

RNA structure determination using SAXS data.

Yang S, Parisien M, Major F, Roux B.

J Phys Chem B. 2010 Aug 12;114(31):10039-48. doi: 10.1021/jp1057308.

22.

RKB: a Semantic Web knowledge base for RNA.

Cruz-Toledo J, Dumontier M, Parisien M, Major F.

J Biomed Semantics. 2010 Jun 22;1 Suppl 1:S2. doi: 10.1186/2041-1480-1-S1-S2.

23.

Designing small multiple-target artificial RNAs.

De Guire V, Caron M, Scott N, Ménard C, Gaumont-Leclerc MF, Chartrand P, Major F, Ferbeyre G.

Nucleic Acids Res. 2010 Jul;38(13):e140. doi: 10.1093/nar/gkq354. Epub 2010 May 7.

24.

Recognition and coupling of A-to-I edited sites are determined by the tertiary structure of the RNA.

Ensterö M, Daniel C, Wahlstedt H, Major F, Ohman M.

Nucleic Acids Res. 2009 Nov;37(20):6916-26. doi: 10.1093/nar/gkp731. Epub 2009 Sep 8.

25.

New metrics for comparing and assessing discrepancies between RNA 3D structures and models.

Parisien M, Cruz JA, Westhof E, Major F.

RNA. 2009 Oct;15(10):1875-85. doi: 10.1261/rna.1700409. Epub 2009 Aug 26.

26.

CD-spectroscopy as a powerful tool for investigating the mode of action of unmodified drugs in live cells.

Tietze LF, Krewer B, Major F, Schuberth I.

J Am Chem Soc. 2009 Sep 16;131(36):13031-6. doi: 10.1021/ja902767f.

PMID:
19697908
27.

Synthesis and biological evaluation of a novel pentagastrin-toxin conjugate designed for a targeted prodrug mono-therapy of cancer.

Tietze LF, Panknin O, Krewer B, Major F, Schuberth I.

Int J Mol Sci. 2008 May;9(5):821-37. doi: 10.3390/ijms9050821. Epub 2008 May 20.

28.

[The invention of the concept of continuing on in during difficult times].

Major FA.

Rech Soins Infirm. 2008 Dec;(95):23-36. French.

PMID:
19195342
29.

Molecular basis of TRAP-5'SL RNA interaction in the Bacillus subtilis trp operon transcription attenuation mechanism.

McGraw AP, Mokdad A, Major F, Bevilacqua PC, Babitzke P.

RNA. 2009 Jan;15(1):55-66. doi: 10.1261/rna.1314409. Epub 2008 Nov 25.

30.

Asymmetric synthesis and biological evaluation of glycosidic prodrugs for a selective cancer therapy.

Tietze LF, von Hof JM, Krewer B, Müller M, Major F, Schuster HJ, Schuberth I, Alves F.

ChemMedChem. 2008 Dec;3(12):1946-55. doi: 10.1002/cmdc.200800250.

PMID:
19021160
31.

The MC-Fold and MC-Sym pipeline infers RNA structure from sequence data.

Parisien M, Major F.

Nature. 2008 Mar 6;452(7183):51-5. doi: 10.1038/nature06684.

PMID:
18322526
32.

Role of SLV in SLI substrate recognition by the Neurospora VS ribozyme.

Bouchard P, Lacroix-Labonté J, Desjardins G, Lampron P, Lisi V, Lemieux S, Major F, Legault P.

RNA. 2008 Apr;14(4):736-48. doi: 10.1261/rna.824308. Epub 2008 Feb 26.

33.

Synthesis of a novel pentagastrin-drug conjugate for a targeted tumor therapy.

Tietze LF, Panknin O, Major F, Krewer B.

Chemistry. 2008;14(9):2811-8. doi: 10.1002/chem.200701521.

PMID:
18214880
34.
35.

Ranking the factors that contribute to protein beta-sheet folding.

Parisien M, Major F.

Proteins. 2007 Sep 1;68(4):824-9.

PMID:
17523189
36.

Staufen1 regulates diverse classes of mammalian transcripts.

Kim YK, Furic L, Parisien M, Major F, DesGroseillers L, Maquat LE.

EMBO J. 2007 Jun 6;26(11):2670-81. Epub 2007 May 17.

37.

Selective treatment of cancer: synthesis, biological evaluation and structural elucidation of novel analogues of the antibiotic CC-1065 and the duocarmycins.

Tietze LF, Major F, Schuberth I, Spiegl DA, Krewer B, Maksimenka K, Bringmann G, Magull J.

Chemistry. 2007;13(16):4396-409.

PMID:
17455190
38.

Modeling RNA tertiary structure motifs by graph-grammars.

St-Onge K, Thibault P, Hamel S, Major F.

Nucleic Acids Res. 2007;35(5):1726-36. Epub 2007 Feb 21.

39.

An E2F/miR-20a autoregulatory feedback loop.

Sylvestre Y, De Guire V, Querido E, Mukhopadhyay UK, Bourdeau V, Major F, Ferbeyre G, Chartrand P.

J Biol Chem. 2007 Jan 26;282(4):2135-43. Epub 2006 Nov 29.

40.

Antitumor agents: development of highly potent glycosidic duocarmycin analogues for selective cancer therapy.

Tietze LF, Major F, Schuberth I.

Angew Chem Int Ed Engl. 2006 Oct 6;45(39):6574-7. No abstract available.

PMID:
16960905
41.

Investigation of reactivity and selectivity of DNA-alkylating duocarmycin analogues by high-resolution mass spectrometry.

Tietze LF, Krewer B, Frauendorf H, Major F, Schuberth I.

Angew Chem Int Ed Engl. 2006 Oct 6;45(39):6570-4. No abstract available.

PMID:
16960904
42.

Automated extraction and classification of RNA tertiary structure cyclic motifs.

Lemieux S, Major F.

Nucleic Acids Res. 2006 May 5;34(8):2340-6. Print 2006.

43.

The RNA Ontology Consortium: an open invitation to the RNA community.

Leontis NB, Altman RB, Berman HM, Brenner SE, Brown JW, Engelke DR, Harvey SC, Holbrook SR, Jossinet F, Lewis SE, Major F, Mathews DH, Richardson JS, Williamson JR, Westhof E.

RNA. 2006 Apr;12(4):533-41. Epub 2006 Feb 16.

44.

Identification of two distinct intracellular localization signals in STT3-B.

Caron E, Côté C, Parisien M, Major F, Perreault C.

Arch Biochem Biophys. 2006 Jan 1;445(1):108-14. Epub 2005 Nov 2.

PMID:
16297371
45.

A 6374 unigene set corresponding to low abundance transcripts expressed following fertilization in Solanum chacoense Bitt, and characterization of 30 receptor-like kinases.

Germain H, Rudd S, Zotti C, Caron S, O'Brien M, Chantha SC, Lagacé M, Major F, Matton DP.

Plant Mol Biol. 2005 Oct;59(3):515-32.

PMID:
16235114
46.

A new catalog of protein beta-sheets.

Parisien M, Major F.

Proteins. 2005 Nov 15;61(3):545-58.

PMID:
16184601
47.

Block of delayed-rectifier potassium channels by reduced haloperidol and related compounds in mouse cortical neurons.

Yang SB, Major F, Tietze LF, Rupnik M.

J Pharmacol Exp Ther. 2005 Oct;315(1):352-62. Epub 2005 Jul 12.

PMID:
16014573
48.

Identification of a conserved RNA motif essential for She2p recognition and mRNA localization to the yeast bud.

Olivier C, Poirier G, Gendron P, Boisgontier A, Major F, Chartrand P.

Mol Cell Biol. 2005 Jun;25(11):4752-66.

49.

Genetic mapping of activity determinants within cellular prion proteins: N-terminal modules in PrPC offset pro-apoptotic activity of the Doppel helix B/B' region.

Drisaldi B, Coomaraswamy J, Mastrangelo P, Strome B, Yang J, Watts JC, Chishti MA, Marvi M, Windl O, Ahrens R, Major F, Sy MS, Kretzschmar H, Fraser PE, Mount HT, Westaway D.

J Biol Chem. 2004 Dec 31;279(53):55443-54. Epub 2004 Sep 29.

50.

Mechanism of block of hEag1 K+ channels by imipramine and astemizole.

García-Ferreiro RE, Kerschensteiner D, Major F, Monje F, Stühmer W, Pardo LA.

J Gen Physiol. 2004 Oct;124(4):301-17. Epub 2004 Sep 13.

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