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Items: 40

1.

Polyanionic carbosilane dendrimers prevent hepatitis C virus infection in cell culture.

Sepúlveda-Crespo D, Jiménez JL, Gómez R, De La Mata FJ, Majano PL, Muñoz-Fernández MÁ, Gastaminza P.

Nanomedicine. 2017 Jan;13(1):49-58. doi: 10.1016/j.nano.2016.08.018. Epub 2016 Aug 22.

PMID:
27562210
2.

Mesothelial-to-mesenchymal transition in the pathogenesis of post-surgical peritoneal adhesions.

Sandoval P, Jiménez-Heffernan JA, Guerra-Azcona G, Pérez-Lozano ML, Rynne-Vidal Á, Albar-Vizcaíno P, Gil-Vera F, Martín P, Coronado MJ, Barcena C, Dotor J, Majano PL, Peralta AA, López-Cabrera M.

J Pathol. 2016 May;239(1):48-59. doi: 10.1002/path.4695. Epub 2016 Mar 23.

PMID:
27071481
3.

Apolipoprotein E, but Not Apolipoprotein B, Is Essential for Efficient Cell-to-Cell Transmission of Hepatitis C Virus.

Gondar V, Molina-Jiménez F, Hishiki T, García-Buey L, Koutsoudakis G, Shimotohno K, Benedicto I, Majano PL.

J Virol. 2015 Oct;89(19):9962-73. doi: 10.1128/JVI.00577-15. Epub 2015 Jul 22.

4.

Clathrin mediates infectious hepatitis C virus particle egress.

Benedicto I, Gondar V, Molina-Jiménez F, García-Buey L, López-Cabrera M, Gastaminza P, Majano PL.

J Virol. 2015 Apr;89(8):4180-90. doi: 10.1128/JVI.03620-14. Epub 2015 Jan 28.

5.

Apicobasal polarity controls lymphocyte adhesion to hepatic epithelial cells.

Reglero-Real N, Álvarez-Varela A, Cernuda-Morollón E, Feito J, Marcos-Ramiro B, Fernández-Martín L, Gómez-Lechón MJ, Muntané J, Sandoval P, Majano PL, Correas I, Alonso MA, Millán J.

Cell Rep. 2014 Sep 25;8(6):1879-1893. doi: 10.1016/j.celrep.2014.08.007. Epub 2014 Sep 18.

6.

Modulation of PI3K-LXRα-dependent lipogenesis mediated by oxidative/nitrosative stress contributes to inhibition of HCV replication by quercetin.

Pisonero-Vaquero S, García-Mediavilla MV, Jorquera F, Majano PL, Benet M, Jover R, González-Gallego J, Sánchez-Campos S.

Lab Invest. 2014 Mar;94(3):262-74. doi: 10.1038/labinvest.2013.156. Epub 2014 Feb 3.

7.

Carcinoma-associated fibroblasts derive from mesothelial cells via mesothelial-to-mesenchymal transition in peritoneal metastasis.

Sandoval P, Jiménez-Heffernan JA, Rynne-Vidal Á, Pérez-Lozano ML, Gilsanz Á, Ruiz-Carpio V, Reyes R, García-Bordas J, Stamatakis K, Dotor J, Majano PL, Fresno M, Cabañas C, López-Cabrera M.

J Pathol. 2013 Dec;231(4):517-31. doi: 10.1002/path.4281.

8.

Functional relevance of the switch of VEGF receptors/co-receptors during peritoneal dialysis-induced mesothelial to mesenchymal transition.

Pérez-Lozano ML, Sandoval P, Rynne-Vidal A, Aguilera A, Jiménez-Heffernan JA, Albar-Vizcaíno P, Majano PL, Sánchez-Tomero JA, Selgas R, López-Cabrera M.

PLoS One. 2013 Apr 9;8(4):e60776. doi: 10.1371/journal.pone.0060776. Print 2013.

9.

Role of tight junctions in hepatitis C virus infection.

Benedicto I, Molina-Jiménez F, García-Buey L, Gondar V, López-Cabrera M, Moreno-Otero R, Majano PL.

Rev Esp Enferm Dig. 2012 May;104(5):255-63. Review. No abstract available.

10.

Liver X receptor α-mediated regulation of lipogenesis by core and NS5A proteins contributes to HCV-induced liver steatosis and HCV replication.

García-Mediavilla MV, Pisonero-Vaquero S, Lima-Cabello E, Benedicto I, Majano PL, Jorquera F, González-Gallego J, Sánchez-Campos S.

Lab Invest. 2012 Aug;92(8):1191-202. doi: 10.1038/labinvest.2012.88. Epub 2012 May 28.

11.

Matrigel-embedded 3D culture of Huh-7 cells as a hepatocyte-like polarized system to study hepatitis C virus cycle.

Molina-Jimenez F, Benedicto I, Dao Thi VL, Gondar V, Lavillette D, Marin JJ, Briz O, Moreno-Otero R, Aldabe R, Baumert TF, Cosset FL, Lopez-Cabrera M, Majano PL.

Virology. 2012 Mar 30;425(1):31-9. doi: 10.1016/j.virol.2011.12.021. Epub 2012 Jan 24.

12.

Blocking TGF-β1 protects the peritoneal membrane from dialysate-induced damage.

Loureiro J, Aguilera A, Selgas R, Sandoval P, Albar-Vizcaíno P, Pérez-Lozano ML, Ruiz-Carpio V, Majano PL, Lamas S, Rodríguez-Pascual F, Borras-Cuesta F, Dotor J, López-Cabrera M.

J Am Soc Nephrol. 2011 Sep;22(9):1682-95. doi: 10.1681/ASN.2010111197. Epub 2011 Jul 8.

13.

Interplay among cellular polarization, lipoprotein metabolism and hepatitis C virus entry.

Benedicto I, Molina-Jiménez F, Moreno-Otero R, López-Cabrera M, Majano PL.

World J Gastroenterol. 2011 Jun 14;17(22):2683-90. doi: 10.3748/wjg.v17.i22.2683.

14.

Expression of pituitary tumor-transforming gene 1 (PTTG1)/securin in hepatitis B virus (HBV)-associated liver diseases: evidence for an HBV X protein-mediated inhibition of PTTG1 ubiquitination and degradation.

Molina-Jiménez F, Benedicto I, Murata M, Martín-Vílchez S, Seki T, Antonio Pintor-Toro J, Tortolero M, Moreno-Otero R, Okazaki K, Koike K, Barbero JL, Matsuzaki K, Majano PL, López-Cabrera M.

Hepatology. 2010 Mar;51(3):777-87. doi: 10.1002/hep.23468.

15.

The tight junction-associated protein occludin is required for a postbinding step in hepatitis C virus entry and infection.

Benedicto I, Molina-Jiménez F, Bartosch B, Cosset FL, Lavillette D, Prieto J, Moreno-Otero R, Valenzuela-Fernández A, Aldabe R, López-Cabrera M, Majano PL.

J Virol. 2009 Aug;83(16):8012-20. doi: 10.1128/JVI.00038-09. Epub 2009 Jun 10.

16.

Hepatitis C virus NS5A and core proteins induce oxidative stress-mediated calcium signalling alterations in hepatocytes.

Dionisio N, Garcia-Mediavilla MV, Sanchez-Campos S, Majano PL, Benedicto I, Rosado JA, Salido GM, Gonzalez-Gallego J.

J Hepatol. 2009 May;50(5):872-82. doi: 10.1016/j.jhep.2008.12.026. Epub 2009 Feb 26.

PMID:
19303156
17.

Hepatitis C virus envelope components alter localization of hepatocyte tight junction-associated proteins and promote occludin retention in the endoplasmic reticulum.

Benedicto I, Molina-Jiménez F, Barreiro O, Maldonado-Rodríguez A, Prieto J, Moreno-Otero R, Aldabe R, López-Cabrera M, Majano PL.

Hepatology. 2008 Oct;48(4):1044-53. doi: 10.1002/hep.22465.

PMID:
18802961
18.

The hepatitis B virus X protein induces paracrine activation of human hepatic stellate cells.

Martín-Vílchez S, Sanz-Cameno P, Rodríguez-Muñoz Y, Majano PL, Molina-Jiménez F, López-Cabrera M, Moreno-Otero R, Lara-Pezzi E.

Hepatology. 2008 Jun;47(6):1872-83. doi: 10.1002/hep.22265.

PMID:
18449922
19.

AM3, a natural glycoconjugate, induces the functional maturation of human dendritic cells.

Martín-Vilchez S, Molina-Jiménez F, Alonso-Lebrero JL, Sanz-Cameno P, Rodríguez-Muñoz Y, Benedicto I, Roda-Navarro P, Trapero M, Aragoneses-Fenoll L, González S, Pivel JP, Corbí AL, López-Cabrera M, Moreno-Otero R, Majano PL.

Br J Pharmacol. 2008 Jun;154(3):698-708. doi: 10.1038/bjp.2008.87. Epub 2008 Apr 14.

20.

Differential contribution of hepatitis C virus NS5A and core proteins to the induction of oxidative and nitrosative stress in human hepatocyte-derived cells.

García-Mediavilla MV, Sánchez-Campos S, González-Pérez P, Gómez-Gonzalo M, Majano PL, López-Cabrera M, Clemente G, García-Monzón C, González-Gallego J.

J Hepatol. 2005 Oct;43(4):606-13.

PMID:
16112247
21.

Gene expression profile of T-cell-specific chemokines in human hepatocyte-derived cells: evidence for a synergistic inducer effect of cytokines and hepatitis C virus proteins.

Apolinario A, Majano PL, Lorente R, Núñez O, Clemente G, García-Monzón C.

J Viral Hepat. 2005 Jan;12(1):27-37.

PMID:
15655045
22.

Increased intrahepatic cyclooxygenase 2, matrix metalloproteinase 2, and matrix metalloproteinase 9 expression is associated with progressive liver disease in chronic hepatitis C virus infection: role of viral core and NS5A proteins.

Núñez O, Fernández-Martínez A, Majano PL, Apolinario A, Gómez-Gonzalo M, Benedicto I, López-Cabrera M, Boscá L, Clemente G, García-Monzón C, Martín-Sanz P.

Gut. 2004 Nov;53(11):1665-72.

23.

Thymidylate synthase expression pattern is a prognostic factor in patients of colorectal cancer treated with 5-fluorouracil.

Fernández-Contreras ME, Jiménez De Ayala B, García De Paredes ML, Velasco A, Majano PL, Palacios J, Gamallo C.

Int J Oncol. 2004 Oct;25(4):877-85.

PMID:
15375535
24.

N-Acetyl-cysteine modulates inducible nitric oxide synthase gene expression in human hepatocytes.

Majano PL, Medina J, Zubía I, Sunyer L, Lara-Pezzi E, Maldonado-Rodríguez A, López-Cabrera M, Moreno-Otero R.

J Hepatol. 2004 Apr;40(4):632-7.

PMID:
15030979
25.

Increased circulating and intrahepatic T-cell-specific chemokines in chronic hepatitis C: relationship with the type of virological response to peginterferon plus ribavirin combination therapy.

Apolinario A, Diago M, Lo Iacono O, Lorente R, Pérez C, Majano PL, Clemente G, García-Monzón C.

Aliment Pharmacol Ther. 2004 Mar 1;19(5):551-62.

PMID:
14987324
26.

Hepatocyte growth factor activates endothelial proangiogenic mechanisms relevant in chronic hepatitis C-associated neoangiogenesis.

Medina J, Caveda L, Sanz-Cameno P, Arroyo AG, Martín-Vílchez S, Majano PL, García-Buey L, Sánchez-Madrid F, Moreno-Otero R.

J Hepatol. 2003 May;38(5):660-7.

PMID:
12713878
27.

The mitogenic activity of the liver growth factor is mediated by tumor necrosis factor alpha in rat liver.

Díaz-Gil JJ, Majano PL, López-Cabrera M, Sánchez-López V, Rúa C, Machín C, Trilla C, García-Cañero R, Moreno-Otero R.

J Hepatol. 2003 May;38(5):598-604.

PMID:
12713870
28.

Does nitric oxide play a pathogenic role in hepatitis C virus infection?

Majano PL, Garcia-Monzon C.

Cell Death Differ. 2003 Jan;10 Suppl 1:S13-5. Review. No abstract available.

29.

Increased expression of T cell chemokines and their receptors in chronic hepatitis C: relationship with the histological activity of liver disease.

Apolinario A, Majano PL, Alvarez-Pérez E, Saez A, Lozano C, Vargas J, García-Monzón C.

Am J Gastroenterol. 2002 Nov;97(11):2861-70.

PMID:
12425561
30.

S-Adenosylmethionine modulates inducible nitric oxide synthase gene expression in rat liver and isolated hepatocytes.

Majano PL, García-Monzón C, García-Trevijano ER, Corrales FJ, Cámara J, Ortiz P, Mato JM, Avila MA, Moreno-Otero R.

J Hepatol. 2001 Dec;35(6):692-9.

PMID:
11738094
31.

Nuclear factor-kappa B in the liver of patients with chronic hepatitis C: decreased RelA expression is associated with enhanced fibrosis progression.

Boya P, Larrea E, Sola I, Majano PL, Jiménez C, Civeira MP, Prieto J.

Hepatology. 2001 Nov;34(5):1041-8.

32.

Effect of the hepatitis B virus HBx protein on integrin-mediated adhesion to and migration on extracellular matrix.

Lara-Pezzi E, Majano PL, Yáñez-Mó M, Gómez-Gonzalo M, Carretero M, Moreno-Otero R, Sánchez-Madrid F, López-Cabrera M.

J Hepatol. 2001 Mar;34(3):409-15.

PMID:
11322202
33.

Intrahepatic expression of inducible nitric oxide synthase in acute liver allograft rejection: evidence of modulation by corticosteroids.

Romero M, García-Monzón C, Clemente G, Salcedo M, Alvarez E, Majano PL, Moreno-Otero R.

Liver Transpl. 2001 Jan;7(1):16-21.

34.

Characterization of pathogenic and prognostic factors of nonalcoholic steatohepatitis associated with obesity.

García-Monzón C, Martín-Pérez E, Iacono OL, Fernández-Bermejo M, Majano PL, Apolinario A, Larrañaga E, Moreno-Otero R.

J Hepatol. 2000 Nov;33(5):716-24. Erratum in: J Hepatol 2001 Jan;34(1):180.

PMID:
11097478
35.

Intrahepatic accumulation of nitrotyrosine in chronic viral hepatitis is associated with histological severity of liver disease.

García-Monzón C, Majano PL, Zubia I, Sanz P, Apolinario A, Moreno-Otero R.

J Hepatol. 2000 Feb;32(2):331-8.

PMID:
10707875
36.

The hepatitis B virus X protein activates nuclear factor of activated T cells (NF-AT) by a cyclosporin A-sensitive pathway.

Lara-Pezzi E, Armesilla AL, Majano PL, Redondo JM, López-Cabrera M.

EMBO J. 1998 Dec 1;17(23):7066-77.

37.

The hepatitis B virus X protein up-regulates tumor necrosis factor alpha gene expression in hepatocytes.

Lara-Pezzi E, Majano PL, Gómez-Gonzalo M, García-Monzón C, Moreno-Otero R, Levrero M, López-Cabrera M.

Hepatology. 1998 Oct;28(4):1013-21.

PMID:
9755238
38.

Intrahepatic enhanced expression of beta2-microglobulin conformational epitope in acute liver allograft rejection: evidence of modulation by glucocorticoids.

García-Monzón C, Majano PL, Solís JA, Rodríguez S, Colina F, López-Botet M, Moreno-González E, Moreno-Otero R.

Dig Dis Sci. 1998 Aug;43(8):1755-62.

PMID:
9724165
39.

Inducible nitric oxide synthase expression in chronic viral hepatitis. Evidence for a virus-induced gene upregulation.

Majano PL, García-Monzón C, López-Cabrera M, Lara-Pezzi E, Fernández-Ruiz E, García-Iglesias C, Borque MJ, Moreno-Otero R.

J Clin Invest. 1998 Apr 1;101(7):1343-52.

40.

Integrins: structure, biological functions and relevance in viral chronic hepatitis.

Garcia-Monzon C, Garcia-Buey L, Majano PL, Moreno-Otero R.

Eur J Clin Invest. 1995 Feb;25(2):71-8. Review. No abstract available.

PMID:
7737265

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