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Items: 1 to 50 of 137

1.

Causal roles of mitochondrial dynamics in longevity and healthy aging.

Sharma A, Smith HJ, Yao P, Mair WB.

EMBO Rep. 2019 Dec 5;20(12):e48395. doi: 10.15252/embr.201948395. Epub 2019 Oct 31. Review.

PMID:
31667999
2.

Neuronal TORC1 modulates longevity via AMPK and cell nonautonomous regulation of mitochondrial dynamics in C. elegans.

Zhang Y, Lanjuin A, Chowdhury SR, Mistry M, Silva-García CG, Weir HJ, Lee CL, Escoubas CC, Tabakovic E, Mair WB.

Elife. 2019 Aug 14;8. pii: e49158. doi: 10.7554/eLife.49158.

3.

Single-Copy Knock-In Loci for Defined Gene Expression in Caenorhabditis elegans.

Silva-García CG, Lanjuin A, Heintz C, Dutta S, Clark NM, Mair WB.

G3 (Bethesda). 2019 Jul 9;9(7):2195-2198. doi: 10.1534/g3.119.400314.

4.

Ultra-performance liquid chromatography-mass spectrometry for precise fatty acid profiling of oilseed crops.

Chernova A, Mazin P, Goryunova S, Goryunov D, Demurin Y, Gorlova L, Vanyushkina A, Mair W, Anikanov N, Yushina E, Pavlova A, Martynova E, Garkusha S, Mukhina Z, Savenko E, Khaitovich P.

PeerJ. 2019 Mar 6;7:e6547. doi: 10.7717/peerj.6547. eCollection 2019.

5.

LINC00116 codes for a mitochondrial peptide linking respiration and lipid metabolism.

Chugunova A, Loseva E, Mazin P, Mitina A, Navalayeu T, Bilan D, Vishnyakova P, Marey M, Golovina A, Serebryakova M, Pletnev P, Rubtsova M, Mair W, Vanyushkina A, Khaitovich P, Belousov V, Vysokikh M, Sergiev P, Dontsova O.

Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):4940-4945. doi: 10.1073/pnas.1809105116. Epub 2019 Feb 22.

6.

UPLC⁻MS Triglyceride Profiling in Sunflower and Rapeseed Seeds.

Chernova A, Gubaev R, Mazin P, Goryunova S, Demurin Y, Gorlova L, Vanushkina A, Mair W, Anikanov N, Martynova E, Goryunov D, Garkusha S, Mukhina Z, Khaytovich P.

Biomolecules. 2018 Dec 27;9(1). pii: E9. doi: 10.3390/biom9010009.

7.

Deregulation of CRTCs in Aging and Age-Related Disease Risk: (Trends in Genetics, 33, 303-321, 2017).

Escoubas CC, Silva-García CG, Mair WB.

Trends Genet. 2018 Apr;34(4):326. doi: 10.1016/j.tig.2018.01.008. Epub 2018 Mar 7. No abstract available.

PMID:
29398010
8.

Dietary Restriction and AMPK Increase Lifespan via Mitochondrial Network and Peroxisome Remodeling.

Weir HJ, Yao P, Huynh FK, Escoubas CC, Goncalves RL, Burkewitz K, Laboy R, Hirschey MD, Mair WB.

Cell Metab. 2017 Dec 5;26(6):884-896.e5. doi: 10.1016/j.cmet.2017.09.024. Epub 2017 Oct 26.

9.

Corrigendum: Splicing factor 1 modulates dietary restriction and TORC1 pathway longevity in C. elegans.

Heintz C, Doktor TK, Lanjuin A, Escoubas CC, Zhang Y, Weir HJ, Dutta S, Silva-García CG, Bruun GH, Morantte I, Hoxhaj G, Manning BD, Andresen BS, Mair WB.

Nature. 2017 Jul 27;547(7664):476. doi: 10.1038/nature23313. Epub 2017 Jul 12.

PMID:
28700577
10.

Mono-unsaturated fatty acids link H3K4me3 modifiers to C. elegans lifespan.

Han S, Schroeder EA, Silva-García CG, Hebestreit K, Mair WB, Brunet A.

Nature. 2017 Apr 13;544(7649):185-190. doi: 10.1038/nature21686. Epub 2017 Apr 5.

11.

Deregulation of CRTCs in Aging and Age-Related Disease Risk.

Escoubas CC, Silva-García CG, Mair WB.

Trends Genet. 2017 May;33(5):303-321. doi: 10.1016/j.tig.2017.03.002. Epub 2017 Mar 30. Review. Erratum in: Trends Genet. 2018 Feb 1;:.

12.

Splicing factor 1 modulates dietary restriction and TORC1 pathway longevity in C. elegans.

Heintz C, Doktor TK, Lanjuin A, Escoubas C, Zhang Y, Weir HJ, Dutta S, Silva-García CG, Bruun GH, Morantte I, Hoxhaj G, Manning BD, Andresen BS, Mair WB.

Nature. 2017 Jan 5;541(7635):102-106. doi: 10.1038/nature20789. Epub 2016 Dec 5. Erratum in: Nature. 2017 Jul 27;547(7664):476.

13.

AMPK as a Pro-longevity Target.

Burkewitz K, Weir HJ, Mair WB.

Exp Suppl. 2016;107:227-256. Review.

PMID:
27812983
14.

Demethylase Inhibitor Fungicide Resistance in Pyrenophora teres f. sp. teres Associated with Target Site Modification and Inducible Overexpression of Cyp51.

Mair WJ, Deng W, Mullins JG, West S, Wang P, Besharat N, Ellwood SR, Oliver RP, Lopez-Ruiz FJ.

Front Microbiol. 2016 Aug 19;7:1279. doi: 10.3389/fmicb.2016.01279. eCollection 2016.

15.

Human iPSC-Derived Neuronal Model of Tau-A152T Frontotemporal Dementia Reveals Tau-Mediated Mechanisms of Neuronal Vulnerability.

Silva MC, Cheng C, Mair W, Almeida S, Fong H, Biswas MHU, Zhang Z, Huang Y, Temple S, Coppola G, Geschwind DH, Karydas A, Miller BL, Kosik KS, Gao FB, Steen JA, Haggarty SJ.

Stem Cell Reports. 2016 Sep 13;7(3):325-340. doi: 10.1016/j.stemcr.2016.08.001. Epub 2016 Sep 1.

16.

SnapShot: Neuronal Regulation of Aging.

Weir HJ, Mair WB.

Cell. 2016 Jul 28;166(3):784-784.e1. doi: 10.1016/j.cell.2016.07.022.

17.

Synthetic Ligands of Cannabinoid Receptors Affect Dauer Formation in the Nematode Caenorhabditis elegans.

Reis Rodrigues P, Kaul TK, Ho JH, Lucanic M, Burkewitz K, Mair WB, Held JM, Bohn LM, Gill MS.

G3 (Bethesda). 2016 Jun 1;6(6):1695-705. doi: 10.1534/g3.116.026997.

18.

Proposal for a unified nomenclature for target-site mutations associated with resistance to fungicides.

Mair W, Lopez-Ruiz F, Stammler G, Clark W, Burnett F, Hollomon D, Ishii H, Thind TS, Brown JK, Fraaije B, Cools H, Shaw M, Fillinger S, Walker AS, Mellado E, Schnabel G, Mehl A, Oliver RP.

Pest Manag Sci. 2016 Aug;72(8):1449-59. doi: 10.1002/ps.4301. Epub 2016 Jun 16.

19.

A Systems Approach to Reverse Engineer Lifespan Extension by Dietary Restriction.

Hou L, Wang D, Chen D, Liu Y, Zhang Y, Cheng H, Xu C, Sun N, McDermott J, Mair WB, Han JD.

Cell Metab. 2016 Mar 8;23(3):529-40. doi: 10.1016/j.cmet.2016.02.002.

20.

FLEXITau: Quantifying Post-translational Modifications of Tau Protein in Vitro and in Human Disease.

Mair W, Muntel J, Tepper K, Tang S, Biernat J, Seeley WW, Kosik KS, Mandelkow E, Steen H, Steen JA.

Anal Chem. 2016 Apr 5;88(7):3704-14. doi: 10.1021/acs.analchem.5b04509. Epub 2016 Mar 7.

21.

Hepatic Bmal1 Regulates Rhythmic Mitochondrial Dynamics and Promotes Metabolic Fitness.

Jacobi D, Liu S, Burkewitz K, Kory N, Knudsen NH, Alexander RK, Unluturk U, Li X, Kong X, Hyde AL, Gangl MR, Mair WB, Lee CH.

Cell Metab. 2015 Oct 6;22(4):709-20. doi: 10.1016/j.cmet.2015.08.006. Epub 2015 Sep 10.

22.

Neuronal CRTC-1 governs systemic mitochondrial metabolism and lifespan via a catecholamine signal.

Burkewitz K, Morantte I, Weir HJM, Yeo R, Zhang Y, Huynh FK, Ilkayeva OR, Hirschey MD, Grant AR, Mair WB.

Cell. 2015 Feb 26;160(5):842-855. doi: 10.1016/j.cell.2015.02.004.

23.

Endogenous hydrogen sulfide production is essential for dietary restriction benefits.

Hine C, Harputlugil E, Zhang Y, Ruckenstuhl C, Lee BC, Brace L, Longchamp A, Treviño-Villarreal JH, Mejia P, Ozaki CK, Wang R, Gladyshev VN, Madeo F, Mair WB, Mitchell JR.

Cell. 2015 Jan 15;160(1-2):132-44. doi: 10.1016/j.cell.2014.11.048. Epub 2014 Dec 23.

24.

Feedback regulation via AMPK and HIF-1 mediates ROS-dependent longevity in Caenorhabditis elegans.

Hwang AB, Ryu EA, Artan M, Chang HW, Kabir MH, Nam HJ, Lee D, Yang JS, Kim S, Mair WB, Lee C, Lee SS, Lee SJ.

Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):E4458-67. doi: 10.1073/pnas.1411199111. Epub 2014 Oct 6.

25.

AMPK at the nexus of energetics and aging.

Burkewitz K, Zhang Y, Mair WB.

Cell Metab. 2014 Jul 1;20(1):10-25. doi: 10.1016/j.cmet.2014.03.002. Epub 2014 Apr 10. Review.

26.

You are what you host: microbiome modulation of the aging process.

Heintz C, Mair W.

Cell. 2014 Jan 30;156(3):408-11. doi: 10.1016/j.cell.2014.01.025. Review.

27.

Diaminothiazoles modify Tau phosphorylation and improve the tauopathy in mouse models.

Zhang X, Hernandez I, Rei D, Mair W, Laha JK, Cornwell ME, Cuny GD, Tsai LH, Steen JA, Kosik KS.

J Biol Chem. 2013 Jul 26;288(30):22042-56. doi: 10.1074/jbc.M112.436402. Epub 2013 Jun 4.

28.

Integrin-mediated signaling induced by simian virus 40 leads to transient uncoupling of cortical actin and the plasma membrane.

Stergiou L, Bauer M, Mair W, Bausch-Fluck D, Drayman N, Wollscheid B, Oppenheim A, Pelkmans L.

PLoS One. 2013;8(2):e55799. doi: 10.1371/journal.pone.0055799. Epub 2013 Feb 7.

29.

Tipping the energy balance toward longevity.

Mair W.

Cell Metab. 2013 Jan 8;17(1):5-6. doi: 10.1016/j.cmet.2012.11.011.

30.

SIP-ing the elixir of youth.

Mair W, Steffen KK, Dillin A.

Cell. 2011 Sep 16;146(6):859-60. doi: 10.1016/j.cell.2011.08.026.

31.

Doubling the dose.

Mair W.

PLoS Biol. 2011 Feb 8;9(2):e1001017. doi: 10.1371/journal.pbio.1001017. No abstract available.

32.

Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB.

Mair W, Morantte I, Rodrigues AP, Manning G, Montminy M, Shaw RJ, Dillin A.

Nature. 2011 Feb 17;470(7334):404-8. doi: 10.1038/nature09706.

33.

Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy.

Egan DF, Shackelford DB, Mihaylova MM, Gelino S, Kohnz RA, Mair W, Vasquez DS, Joshi A, Gwinn DM, Taylor R, Asara JM, Fitzpatrick J, Dillin A, Viollet B, Kundu M, Hansen M, Shaw RJ.

Science. 2011 Jan 28;331(6016):456-61. doi: 10.1126/science.1196371. Epub 2010 Dec 23.

34.

How normal cells can win the battle for survival against cancer cells.

Mair W.

PLoS Biol. 2010 Jul 13;8(7):e1000423. doi: 10.1371/journal.pbio.1000423. No abstract available.

35.

Dietary restriction enhances germline stem cell maintenance.

Mair W, McLeod CJ, Wang L, Jones DL.

Aging Cell. 2010 Oct;9(5):916-8. doi: 10.1111/j.1474-9726.2010.00602.x.

36.

Reinforcing reinforcement.

Mair W.

PLoS Biol. 2010 Mar 23;8(3):e1000340. doi: 10.1371/journal.pbio.1000340. No abstract available.

37.

Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes.

Capelson M, Liang Y, Schulte R, Mair W, Wagner U, Hetzer MW.

Cell. 2010 Feb 5;140(3):372-83. doi: 10.1016/j.cell.2009.12.054.

38.

Comparison of the T-tubule system in adult rat ventricular and atrial myocytes, and its role in excitation-contraction coupling and inotropic stimulation.

Smyrnias I, Mair W, Harzheim D, Walker SA, Roderick HL, Bootman MD.

Cell Calcium. 2010 Mar;47(3):210-23. doi: 10.1016/j.ceca.2009.10.001. Epub 2010 Jan 27.

PMID:
20106523
39.

"Induced" eyes suggest a path to retinal repair.

Mair W.

PLoS Biol. 2009 Aug 18;7(8):e1000175. doi: 10.1371/journal.pbio.1000175. No abstract available.

40.

Change for the better: phosphoregulation of proteins drives evolution.

Mair W.

PLoS Biol. 2009 Jun 23;7(6):e1000127. doi: 10.1371/journal.pbio.1000127. No abstract available.

41.

Optimizing dietary restriction for genetic epistasis analysis and gene discovery in C. elegans.

Mair W, Panowski SH, Shaw RJ, Dillin A.

PLoS One. 2009;4(2):e4535. doi: 10.1371/journal.pone.0004535. Epub 2009 Feb 20.

42.

A new view of embryogenesis--connective fibers join the dance.

Mair W.

PLoS Biol. 2008 Oct;6(10):1. doi: 10.1371/journal.pbio.0060268. Epub 2008 Oct 14. No abstract available.

43.

Aging and survival: the genetics of life span extension by dietary restriction.

Mair W, Dillin A.

Annu Rev Biochem. 2008;77:727-54. doi: 10.1146/annurev.biochem.77.061206.171059. Review.

PMID:
18373439
44.
46.

The effect of dietary restriction on mitochondrial protein density and flight muscle mitochondrial morphology in Drosophila.

Magwere T, Goodall S, Skepper J, Mair W, Brand MD, Partridge L.

J Gerontol A Biol Sci Med Sci. 2006 Jan;61(1):36-47.

PMID:
16456193
47.

Calories do not explain extension of life span by dietary restriction in Drosophila.

Mair W, Piper MD, Partridge L.

PLoS Biol. 2005 Jul;3(7):e223. Epub 2005 May 31.

48.

Counting the calories: the role of specific nutrients in extension of life span by food restriction.

Piper MD, Mair W, Partridge L.

J Gerontol A Biol Sci Med Sci. 2005 May;60(5):549-55. Review.

PMID:
15972601
49.

Dietary restriction in Drosophila.

Partridge L, Piper MD, Mair W.

Mech Ageing Dev. 2005 Sep;126(9):938-50. Review.

PMID:
15935441
50.

High efficacy and low toxicity of weekly docetaxel given as first-line treatment for metastatic breast cancer.

Stemmler J, Mair W, Stauch M, Papke J, Deutsch G, Abenhardt W, Dorn B, Kentenich C, Malekmohammadi M, Jackisch C, Leinung S, Brudler O, Vehling-Kaiser U, Stamp J, Heinemann V.

Oncology. 2005;68(1):71-8. Epub 2005 Mar 12.

PMID:
15809523

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