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A validated natural language processing algorithm for brain imaging phenotypes from radiology reports in UK electronic health records.

Wheater E, Mair G, Sudlow C, Alex B, Grover C, Whiteley W.

BMC Med Inform Decis Mak. 2019 Sep 9;19(1):184. doi: 10.1186/s12911-019-0908-7.


Functional genetic evaluation of DNA house-cleaning enzymes in the malaria parasite: dUTPase and Ap4AH are essential in Plasmodium berghei but ITPase and NDH are dispensable.

Kumar H, Kehrer J, Singer M, Reinig M, Santos JM, Mair GR, Frischknecht F.

Expert Opin Ther Targets. 2019 Mar;23(3):251-261. doi: 10.1080/14728222.2019.1575810. Epub 2019 Feb 13.


Manually-parcellated gyral data accounting for all known anatomical variability.

Mikhael SS, Mair G, Valdes-Hernandez M, Hoogendoorn C, Wardlaw JM, Bastin ME, Pernet C.

Sci Data. 2019 Jan 29;6:190001. doi: 10.1038/sdata.2019.1.


Transmission of the malaria parasite requires ferlin for gamete egress from the red blood cell.

Obrova K, Cyrklaff M, Frank R, Mair GR, Mueller AK.

Cell Microbiol. 2019 May;21(5):e12999. doi: 10.1111/cmi.12999. Epub 2019 Jan 18.


Effect of IV alteplase on the ischemic brain lesion at 24-48 hours after ischemic stroke.

Mair G, von Kummer R, Morris Z, von Heijne A, Bradey N, Cala L, Peeters A, Farrall AJ, Adami A, Potter G, Sandercock PAG, Lindley RI, Wardlaw JM; IST-3 Collaborative Group.

Neurology. 2018 Nov 27;91(22):e2067-e2077. doi: 10.1212/WNL.0000000000006575. Epub 2018 Oct 26.


Machine learning of neuroimaging for assisted diagnosis of cognitive impairment and dementia: A systematic review.

Pellegrini E, Ballerini L, Hernandez MDCV, Chappell FM, González-Castro V, Anblagan D, Danso S, Muñoz-Maniega S, Job D, Pernet C, Mair G, MacGillivray TJ, Trucco E, Wardlaw JM.

Alzheimers Dement (Amst). 2018 Aug 11;10:519-535. doi: 10.1016/j.dadm.2018.07.004. eCollection 2018.


Nuclear Pore Complex Components in the Malaria Parasite Plasmodium berghei.

Kehrer J, Kuss C, Andres-Pons A, Reustle A, Dahan N, Devos D, Kudryashev M, Beck M, Mair GR, Frischknecht F.

Sci Rep. 2018 Jul 26;8(1):11249. doi: 10.1038/s41598-018-29590-5.


Rapid Automated Quantification of Cerebral Leukoaraiosis on CT Images: A Multicenter Validation Study.

Chen L, Carlton Jones AL, Mair G, Patel R, Gontsarova A, Ganesalingam J, Math N, Dawson A, Aweid B, Cohen D, Mehta A, Wardlaw J, Rueckert D, Bentley P; IST-3 Collaborative Group.

Radiology. 2018 Aug;288(2):573-581. doi: 10.1148/radiol.2018171567. Epub 2018 May 15.


Identification of a Golgi apparatus protein complex important for the asexual erythrocytic cycle of the malaria parasite Plasmodium falciparum.

Hallée S, Thériault C, Gagnon D, Kehrer J, Frischknecht F, Mair GR, Richard D.

Cell Microbiol. 2018 Aug;20(8):e12843. doi: 10.1111/cmi.12843. Epub 2018 Apr 24.


Plasmodium UIS3 sequesters host LC3 to avoid elimination by autophagy in hepatocytes.

Real E, Rodrigues L, Cabal GG, Enguita FJ, Mancio-Silva L, Mello-Vieira J, Beatty W, Vera IM, Zuzarte-Luís V, Figueira TN, Mair GR, Mota MM.

Nat Microbiol. 2018 Jan;3(1):17-25. doi: 10.1038/s41564-017-0054-x. Epub 2017 Nov 6.


Blood pressure variability and leukoaraiosis in acute ischemic stroke.

Dickie DA, Aribisala B, Mair G, Berge E, Lindley RI, Sandercock P, von Kummer R, von Heijne A, Peeters A, Cala L, Farrall A, Morris Z, Bradey N, Potter G, Adami A, Wardlaw JM.

Int J Stroke. 2018 Jul;13(5):473-480. doi: 10.1177/1747493017729267. Epub 2017 Sep 5.


Penumbra and re-canalization acute computed tomography in ischemic stroke evaluation: PRACTISE study protocol.

El-Tawil S, Wardlaw J, Ford I, Mair G, Robinson T, Kalra L, Muir KW.

Int J Stroke. 2017 Aug;12(6):671-678. doi: 10.1177/1747493017696099. Epub 2017 Mar 14.


Malaria parasite LIMP protein regulates sporozoite gliding motility and infectivity in mosquito and mammalian hosts.

Santos JM, Egarter S, Zuzarte-Luís V, Kumar H, Moreau CA, Kehrer J, Pinto A, Costa MD, Franke-Fayard B, Janse CJ, Frischknecht F, Mair GR.

Elife. 2017 May 2;6. pii: e24109. doi: 10.7554/eLife.24109.


Cerebral White Matter Hypoperfusion Increases with Small-Vessel Disease Burden. Data From the Third International Stroke Trial.

Arba F, Mair G, Carpenter T, Sakka E, Sandercock PAG, Lindley RI, Inzitari D, Wardlaw JM; IST-3 Trial Collaborators.

J Stroke Cerebrovasc Dis. 2017 Jul;26(7):1506-1513. doi: 10.1016/j.jstrokecerebrovasdis.2017.03.002. Epub 2017 Mar 15.


Arterial Obstruction on Computed Tomographic or Magnetic Resonance Angiography and Response to Intravenous Thrombolytics in Ischemic Stroke.

Mair G, von Kummer R, Adami A, White PM, Adams ME, Yan B, Demchuk AM, Farrall AJ, Sellar RJ, Sakka E, Palmer J, Perry D, Lindley RI, Sandercock PA, Wardlaw JM; IST-3 Collaborative Group.

Stroke. 2017 Feb;48(2):353-360. doi: 10.1161/STROKEAHA.116.015164. Epub 2016 Dec 22.


A Putative Small Solute Transporter Is Responsible for the Secretion of G377 and TRAP-Containing Secretory Vesicles during Plasmodium Gamete Egress and Sporozoite Motility.

Kehrer J, Singer M, Lemgruber L, Silva PA, Frischknecht F, Mair GR.

PLoS Pathog. 2016 Jul 18;12(7):e1005734. doi: 10.1371/journal.ppat.1005734. eCollection 2016 Jul.


Translational repression of the cpw-wpc gene family in the malaria parasite Plasmodium.

Rao PN, Santos JM, Pain A, Templeton TJ, Mair GR.

Parasitol Int. 2016 Oct;65(5 Pt A):463-71. doi: 10.1016/j.parint.2016.06.007. Epub 2016 Jun 14.


Maternally supplied S-acyl-transferase is required for crystalloid organelle formation and transmission of the malaria parasite.

Santos JM, Duarte N, Kehrer J, Ramesar J, Avramut MC, Koster AJ, Dessens JT, Frischknecht F, Chevalley-Maurel S, Janse CJ, Franke-Fayard B, Mair GR.

Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):7183-8. doi: 10.1073/pnas.1522381113. Epub 2016 Jun 14.


Integrated transcriptomic and proteomic analyses of P. falciparum gametocytes: molecular insight into sex-specific processes and translational repression.

Lasonder E, Rijpma SR, van Schaijk BC, Hoeijmakers WA, Kensche PR, Gresnigt MS, Italiaander A, Vos MW, Woestenenk R, Bousema T, Mair GR, Khan SM, Janse CJ, Bártfai R, Sauerwein RW.

Nucleic Acids Res. 2016 Jul 27;44(13):6087-101. doi: 10.1093/nar/gkw536. Epub 2016 Jun 13.


A small mitochondrial protein present in myzozoans is essential for malaria transmission.

Klug D, Mair GR, Frischknecht F, Douglas RG.

Open Biol. 2016 Apr;6(4):160034. doi: 10.1098/rsob.160034.


The physiological expression of scavenger receptor SR-B1 in canine endometrial and placental epithelial cells and its potential involvement in pathogenesis of pyometra.

Gabriel C, Becher-Deichsel A, Hlavaty J, Mair G, Walter I.

Theriogenology. 2016 Jun;85(9):1599-1609.e2. doi: 10.1016/j.theriogenology.2016.01.021. Epub 2016 Jan 30.


Translational Control of UIS4 Protein of the Host-Parasite Interface Is Mediated by the RNA Binding Protein Puf2 in Plasmodium berghei Sporozoites.

Silva PA, Guerreiro A, Santos JM, Braks JA, Janse CJ, Mair GR.

PLoS One. 2016 Jan 25;11(1):e0147940. doi: 10.1371/journal.pone.0147940. eCollection 2016.


Effect of X-Ray Attenuation of Arterial Obstructions on Intravenous Thrombolysis and Outcome after Ischemic Stroke.

Mair G, von Kummer R, Lindley RI, Sandercock PA, Wardlaw JM; IST-3 Collaborative Group.

PLoS One. 2015 Dec 23;10(12):e0145683. doi: 10.1371/journal.pone.0145683. eCollection 2015.


Effect of alteplase on the CT hyperdense artery sign and outcome after ischemic stroke.

Mair G, von Kummer R, Morris Z, von Heijne A, Bradey N, Cala L, Peeters A, Farrall AJ, Adami A, Potter G, Cohen G, Sandercock PA, Lindley RI, Wardlaw JM; IST-3 Collaborative Group.

Neurology. 2016 Jan 12;86(2):118-25. doi: 10.1212/WNL.0000000000002236. Epub 2015 Dec 9.


Zinc finger nuclease-based double-strand breaks attenuate malaria parasites and reveal rare microhomology-mediated end joining.

Singer M, Marshall J, Heiss K, Mair GR, Grimm D, Mueller AK, Frischknecht F.

Genome Biol. 2015 Nov 17;16:249. doi: 10.1186/s13059-015-0811-1.


The Plasmodium palmitoyl-S-acyl-transferase DHHC2 is essential for ookinete morphogenesis and malaria transmission.

Santos JM, Kehrer J, Franke-Fayard B, Frischknecht F, Janse CJ, Mair GR.

Sci Rep. 2015 Nov 3;5:16034. doi: 10.1038/srep16034.


In silico identification of genetically attenuated vaccine candidate genes for Plasmodium liver stage.

Kumar H, Frischknecht F, Mair GR, Gomes J.

Infect Genet Evol. 2015 Dec;36:72-81. doi: 10.1016/j.meegid.2015.09.002. Epub 2015 Sep 6.


Parasite-induced ER stress response in hepatocytes facilitates Plasmodium liver stage infection.

Inácio P, Zuzarte-Luís V, Ruivo MT, Falkard B, Nagaraj N, Rooijers K, Mann M, Mair G, Fidock DA, Mota MM.

EMBO Rep. 2015 Aug;16(8):955-64. doi: 10.15252/embr.201439979. Epub 2015 Jun 25.


Lack of flow on time-of-flight MR angiography does not always indicate occlusion.

Mair G.

BJR Case Rep. 2015 Jun 10;2(1):20150187. doi: 10.1259/bjrcr.20150187. eCollection 2016.


Sensitivity and specificity of the hyperdense artery sign for arterial obstruction in acute ischemic stroke.

Mair G, Boyd EV, Chappell FM, von Kummer R, Lindley RI, Sandercock P, Wardlaw JM; IST-3 Collaborative Group.

Stroke. 2015 Jan;46(1):102-7. doi: 10.1161/STROKEAHA.114.007036. Epub 2014 Dec 4. Review.


Genome-wide RIP-Chip analysis of translational repressor-bound mRNAs in the Plasmodium gametocyte.

Guerreiro A, Deligianni E, Santos JM, Silva PA, Louis C, Pain A, Janse CJ, Franke-Fayard B, Carret CK, Siden-Kiamos I, Mair GR.

Genome Biol. 2014 Nov 3;15(11):493. doi: 10.1186/s13059-014-0493-0.


Observer reliability of CT angiography in the assessment of acute ischaemic stroke: data from the Third International Stroke Trial.

Mair G, von Kummer R, Adami A, White PM, Adams ME, Yan B, Demchuk AM, Farrall AJ, Sellar RJ, Ramaswamy R, Mollison D, Boyd EV, Rodrigues MA, Samji K, Baird AJ, Cohen G, Sakka E, Palmer J, Perry D, Lindley R, Sandercock PA, Wardlaw JM; IST-3 Collaborative Group.

Neuroradiology. 2015 Jan;57(1):1-9. doi: 10.1007/s00234-014-1441-0. Epub 2014 Oct 7.


Intense illumination in the morning hours improved mood and alertness but not mental performance.

Leichtfried V, Mair-Raggautz M, Schaeffer V, Hammerer-Lercher A, Mair G, Bartenbach C, Canazei M, Schobersberger W.

Appl Ergon. 2015 Jan;46 Pt A:54-9. doi: 10.1016/j.apergo.2014.07.001. Epub 2014 Aug 5.


Sports in LCHAD Deficiency: Maximal Incremental and Endurance Exercise Tests in a 13-Year-Old Patient with Long-Chain 3-Hydroxy Acyl-CoA Dehydrogenase Deficiency (LCHADD) and Heptanoate Treatment.

Karall D, Mair G, Albrecht U, Niedermayr K, Karall T, Schobersberger W, Scholl-Bürgi S.

JIMD Rep. 2014;17:7-12. doi: 10.1007/8904_2014_313. Epub 2014 Jul 6.


Imaging of acute stroke prior to treatment: current practice and evolving techniques.

Mair G, Wardlaw JM.

Br J Radiol. 2014 Aug;87(1040):20140216. doi: 10.1259/bjr.20140216. Epub 2014 Jun 17. Review.


Genetic crosses and complementation reveal essential functions for the Plasmodium stage-specific actin2 in sporogonic development.

Andreadaki M, Morgan RN, Deligianni E, Kooij TW, Santos JM, Spanos L, Matuschewski K, Louis C, Mair GR, Siden-Kiamos I.

Cell Microbiol. 2014 May;16(5):751-67. doi: 10.1111/cmi.12274. Epub 2014 Feb 20.


Human osteosarcoma cells respond to sorafenib chemotherapy by downregulation of the tumor progression factors S100A4, CXCR4 and the oncogene FOS.

Walter I, Wolfesberger B, Miller I, Mair G, Burger S, Gallè B, Steinborn R.

Oncol Rep. 2014 Mar;31(3):1147-56. doi: 10.3892/or.2013.2954. Epub 2013 Dec 30.


Triapine and a more potent dimethyl derivative induce endoplasmic reticulum stress in cancer cells.

Trondl R, Flocke LS, Kowol CR, Heffeter P, Jungwirth U, Mair GE, Steinborn R, Enyedy ÉA, Jakupec MA, Berger W, Keppler BK.

Mol Pharmacol. 2014 Mar;85(3):451-9. doi: 10.1124/mol.113.090605. Epub 2013 Dec 30.


Stress granules and Plasmodium liver stage infection.

Hanson KK, Mair GR.

Biol Open. 2014 Jan 15;3(1):103-7. doi: 10.1242/bio.20136833.


Catechol conjugates are in vivo metabolites of Salicis cortex.

Knuth S, Abdelsalam RM, Khayyal MT, Schweda F, Heilmann J, Kees MG, Mair G, Kees F, Jürgenliemk G.

Planta Med. 2013 Nov;79(16):1489-94. doi: 10.1055/s-0033-1350898. Epub 2013 Oct 21.


Acute Stroke Imaging Research Roadmap II.

Wintermark M, Albers GW, Broderick JP, Demchuk AM, Fiebach JB, Fiehler J, Grotta JC, Houser G, Jovin TG, Lees KR, Lev MH, Liebeskind DS, Luby M, Muir KW, Parsons MW, von Kummer R, Wardlaw JM, Wu O, Yoo AJ, Alexandrov AV, Alger JR, Aviv RI, Bammer R, Baron JC, Calamante F, Campbell BC, Carpenter TC, Christensen S, Copen WA, Derdeyn CP, Haley EC Jr, Khatri P, Kudo K, Lansberg MG, Latour LL, Lee TY, Leigh R, Lin W, Lyden P, Mair G, Menon BK, Michel P, Mikulik R, Nogueira RG, Ostergaard L, Pedraza S, Riedel CH, Rowley HA, Sanelli PC, Sasaki M, Saver JL, Schaefer PW, Schellinger PD, Tsivgoulis G, Wechsler LR, White PM, Zaharchuk G, Zaidat OO, Davis SM, Donnan GA, Furlan AJ, Hacke W, Kang DW, Kidwell C, Thijs VN, Thomalla G, Warach SJ; Stroke Imaging Research (STIR) and Virtual International Stroke Trials Archive (VISTA)-Imaging Investigators.

Stroke. 2013 Sep;44(9):2628-39. doi: 10.1161/STROKEAHA.113.002015. Epub 2013 Jul 16. Review. No abstract available.


Isothermal loop-mediated amplification (LAMP) for diagnosis of contagious bovine pleuro-pneumonia.

Mair G, Vilei EM, Wade A, Frey J, Unger H.

BMC Vet Res. 2013 May 27;9:108. doi: 10.1186/1746-6148-9-108.


Cross-platform microarray meta-analysis for the mouse jejunum selects novel reference genes with highly uniform levels of expression.

Meyer FR, Grausgruber H, Binter C, Mair GE, Guelly C, Vogl C, Steinborn R.

PLoS One. 2013 May 9;8(5):e63125. doi: 10.1371/journal.pone.0063125. Print 2013.


Changes in the transcriptome of the malaria parasite Plasmodium falciparum during the initial phase of transmission from the human to the mosquito.

Ngwa CJ, Scheuermayer M, Mair GR, Kern S, Brügl T, Wirth CC, Aminake MN, Wiesner J, Fischer R, Vilcinskas A, Pradel G.

BMC Genomics. 2013 Apr 15;14:256. doi: 10.1186/1471-2164-14-256.


Loss-of-function analyses defines vital and redundant functions of the Plasmodium rhomboid protease family.

Lin JW, Meireles P, Prudêncio M, Engelmann S, Annoura T, Sajid M, Chevalley-Maurel S, Ramesar J, Nahar C, Avramut CM, Koster AJ, Matuschewski K, Waters AP, Janse CJ, Mair GR, Khan SM.

Mol Microbiol. 2013 Apr;88(2):318-38. doi: 10.1111/mmi.12187. Epub 2013 Mar 12.


Survey of UK radiology trainees in the aftermath of 'Modernising Medical Careers'.

Mair G, Ewing F, Murchison JT.

BMC Med Educ. 2012 Oct 2;12:93. doi: 10.1186/1472-6920-12-93.


Rapid mitochondrial DNA segregation in primate preimplantation embryos precedes somatic and germline bottleneck.

Lee HS, Ma H, Juanes RC, Tachibana M, Sparman M, Woodward J, Ramsey C, Xu J, Kang EJ, Amato P, Mair G, Steinborn R, Mitalipov S.

Cell Rep. 2012 May 31;1(5):506-15.


Genome wide adaptations of Plasmodium falciparum in response to lumefantrine selective drug pressure.

Mwai L, Diriye A, Masseno V, Muriithi S, Feltwell T, Musyoki J, Lemieux J, Feller A, Mair GR, Marsh K, Newbold C, Nzila A, Carret CK.

PLoS One. 2012;7(2):e31623. doi: 10.1371/journal.pone.0031623. Epub 2012 Feb 27.

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