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Items: 1 to 50 of 65

1.

Characterization of pUL5, an HCMV protein interacting with the cellular protein IQGAP1.

Anselmi G, Giuliani M, Vezzani G, Ferranti R, Gentile M, Cortese M, Amendola D, Pacchiani N, D'Aurizio R, Bruno L, Uematsu Y, Merola M, Maione D.

Virology. 2019 Nov 3;540:57-65. doi: 10.1016/j.virol.2019.10.018. [Epub ahead of print]

2.

Cocrystal structure of meningococcal factor H binding protein variant 3 reveals a new crossprotective epitope recognized by human mAb 1E6.

Bianchi F, Veggi D, Santini L, Buricchi F, Bartolini E, Lo Surdo P, Martinelli M, Finco O, Masignani V, Bottomley MJ, Maione D, Cozzi R.

FASEB J. 2019 Nov;33(11):12099-12111. doi: 10.1096/fj.201900374R. Epub 2019 Oct 5.

3.

Co-administration of GM-CSF expressing RNA is a powerful tool to enhance potency of SAM-based vaccines.

Manara C, Brazzoli M, Piccioli D, Taccone M, D'Oro U, Maione D, Frigimelica E.

Vaccine. 2019 Jul 9;37(30):4204-4213. doi: 10.1016/j.vaccine.2019.04.028. Epub 2019 Jun 18.

PMID:
31227353
4.

Retrospective Identification of a Broad IgG Repertoire Differentiating Patients With S. aureus Skin and Soft Tissue Infections From Controls.

Rigat F, Bartolini E, Dalsass M, Kumar N, Marchi S, Speziale P, Maione D, Chen L, Romano MR, Alegre ML, Bagnoli F, Daum RS, David MZ.

Front Immunol. 2019 Feb 7;10:114. doi: 10.3389/fimmu.2019.00114. eCollection 2019.

5.

Human protective response induced by meningococcus B vaccine is mediated by the synergy of multiple bactericidal epitopes.

Giuliani M, Bartolini E, Galli B, Santini L, Lo Surdo P, Buricchi F, Bruttini M, Benucci B, Pacchiani N, Alleri L, Donnarumma D, Pansegrau W, Peschiera I, Ferlenghi I, Cozzi R, Norais N, Giuliani MM, Maione D, Pizza M, Rappuoli R, Finco O, Masignani V.

Sci Rep. 2018 Feb 27;8(1):3700. doi: 10.1038/s41598-018-22057-7.

6.

Immunogenicity and protective efficacy induced by self-amplifying mRNA vaccines encoding bacterial antigens.

Maruggi G, Chiarot E, Giovani C, Buccato S, Bonacci S, Frigimelica E, Margarit I, Geall A, Bensi G, Maione D.

Vaccine. 2017 Jan 5;35(2):361-368. doi: 10.1016/j.vaccine.2016.11.040. Epub 2016 Dec 7.

7.

Human cytomegalovirus pUL10 interacts with leukocytes and impairs TCR-mediated T-cell activation.

Bruno L, Cortese M, Monda G, Gentile M, Calò S, Schiavetti F, Zedda L, Cattaneo E, Piccioli D, Schaefer M, Notomista E, Maione D, Carfì A, Merola M, Uematsu Y.

Immunol Cell Biol. 2016 Oct;94(9):849-860. doi: 10.1038/icb.2016.49. Epub 2016 May 19.

PMID:
27192938
8.

Successful completion of a semi-automated enzyme-free cloning method.

Bonacci S, Buccato S, Maione D, Petracca R.

J Struct Funct Genomics. 2016 Sep;17(2-3):57-66. doi: 10.1007/s10969-016-9207-z. Epub 2016 Aug 9.

PMID:
27507291
9.

The Protective Value of Maternal Group B Streptococcus Antibodies: Quantitative and Functional Analysis of Naturally Acquired Responses to Capsular Polysaccharides and Pilus Proteins in European Maternal Sera.

Fabbrini M, Rigat F, Rinaudo CD, Passalaqua I, Khacheh S, Creti R, Baldassarri L, Carboni F, Anderloni G, Rosini R, Maione D, Grandi G, Telford JL, Margarit I.

Clin Infect Dis. 2016 Sep 15;63(6):746-753. doi: 10.1093/cid/ciw377. Epub 2016 Jul 11.

PMID:
27402816
10.

Exploring host-pathogen interactions through genome wide protein microarray analysis.

Scietti L, Sampieri K, Pinzuti I, Bartolini E, Benucci B, Liguori A, Haag AF, Lo Surdo P, Pansegrau W, Nardi-Dei V, Santini L, Arora S, Leber X, Rindi S, Savino S, Costantino P, Maione D, Merola M, Speziale P, Bottomley MJ, Bagnoli F, Masignani V, Pizza M, Scharenberg M, Schlaeppi JM, Nissum M, Liberatori S.

Sci Rep. 2016 Jun 15;6:27996. doi: 10.1038/srep27996.

11.

The Human Cytomegalovirus UL116 Gene Encodes an Envelope Glycoprotein Forming a Complex with gH Independently from gL.

Caló S, Cortese M, Ciferri C, Bruno L, Gerrein R, Benucci B, Monda G, Gentile M, Kessler T, Uematsu Y, Maione D, Lilja AE, Carfí A, Merola M.

J Virol. 2016 Apr 29;90(10):4926-38. doi: 10.1128/JVI.02517-15. Print 2016 May 15.

12.

Crystal structure of FhuD at 1.6 Å resolution: a ferrichrome-binding protein from the animal and human pathogen Staphylococcus pseudintermedius.

Abate F, Cozzi R, Maritan M, Lo Surdo P, Maione D, Malito E, Bottomley MJ.

Acta Crystallogr F Struct Biol Commun. 2016 Mar;72(Pt 3):214-9. doi: 10.1107/S2053230X16002272. Epub 2016 Feb 19.

13.

Group B streptococcal infections in the newborn infant and the potential value of maternal vaccination.

Berardi A, Cattelani C, Creti R, Berner R, Pietrangiolillo Z, Margarit I, Maione D, Ferrari F.

Expert Rev Anti Infect Ther. 2015;13(11):1387-99. doi: 10.1586/14787210.2015.1079126. Epub 2015 Aug 20. Review.

PMID:
26295167
14.

Group B Streptococcus vaccine: state of the art.

Nuccitelli A, Rinaudo CD, Maione D.

Ther Adv Vaccines. 2015 May;3(3):76-90. doi: 10.1177/2051013615579869. Review.

15.

Expression and Characterization of Recombinant, Tetrameric and Enzymatically Active Influenza Neuraminidase for the Setup of an Enzyme-Linked Lectin-Based Assay.

Prevato M, Ferlenghi I, Bonci A, Uematsu Y, Anselmi G, Giusti F, Bertholet S, Legay F, Telford JL, Settembre EC, Maione D, Cozzi R.

PLoS One. 2015 Aug 17;10(8):e0135474. doi: 10.1371/journal.pone.0135474. eCollection 2015.

16.

Noncanonical sortase-mediated assembly of pilus type 2b in group B Streptococcus.

Lazzarin M, Cozzi R, Malito E, Martinelli M, D'Onofrio M, Maione D, Margarit I, Rinaudo CD.

FASEB J. 2015 Nov;29(11):4629-40. doi: 10.1096/fj.15-272500. Epub 2015 Jul 22.

PMID:
26202865
17.

CD8 T-cell priming upon mRNA vaccination is restricted to bone-marrow-derived antigen-presenting cells and may involve antigen transfer from myocytes.

Lazzaro S, Giovani C, Mangiavacchi S, Magini D, Maione D, Baudner B, Geall AJ, De Gregorio E, D'Oro U, Buonsanti C.

Immunology. 2015 Oct;146(2):312-26. doi: 10.1111/imm.12505. Epub 2015 Aug 28.

18.

The VO(2)-on kinetics in constant load exercise sub-anaerobic threshold reflects endothelial function and dysfunction in muscle microcirculation.

Maione D, Cicero AF, Bacchelli S, Cosentino ER, Degli Esposti D, Manners DN, Rinaldi ER, Rosticci M, Senaldi R, Ambrosioni E, Borghi C.

Physiol Res. 2015;64(6):807-19. Epub 2015 Jun 5.

19.

Structure and assembly of group B streptococcus pilus 2b backbone protein.

Cozzi R, Malito E, Lazzarin M, Nuccitelli A, Castagnetti A, Bottomley MJ, Margarit I, Maione D, Rinaudo CD.

PLoS One. 2015 May 5;10(5):e0125875. doi: 10.1371/journal.pone.0125875. eCollection 2015.

20.

Anti-Group B Streptococcus Glycan-Conjugate Vaccines Using Pilus Protein GBS80 As Carrier and Antigen: Comparing Lysine and Tyrosine-directed Conjugation.

Nilo A, Morelli L, Passalacqua I, Brogioni B, Allan M, Carboni F, Pezzicoli A, Zerbini F, Maione D, Fabbrini M, Romano MR, Hu QY, Margarit I, Berti F, Adamo R.

ACS Chem Biol. 2015 Jul 17;10(7):1737-46. doi: 10.1021/acschembio.5b00247. Epub 2015 May 6.

PMID:
25906283
21.

Corrigendum: Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline.

Da Cunha V, Davies MR, Douarre PE, Rosinski-Chupin I, Margarit I, Spinali S, Perkins T, Lechat P, Dmytruk N, Sauvage E, Ma L, Romi B, Tichit M, Lopez-Sanchez MJ, Descorps-Declere S, Souche E, Buchrieser C, Trieu-Cuot P, Moszer I, Clermont D, Maione D, Bouchier C, McMillan DJ, Parkhill J, Telford JL, Dougan G, Walker MJ, Holden MT, Poyart C, Glaser P.

Nat Commun. 2015 Jan 28;6:6108. doi: 10.1038/ncomms7108. No abstract available.

22.

Self-amplifying mRNA vaccines.

Brito LA, Kommareddy S, Maione D, Uematsu Y, Giovani C, Berlanda Scorza F, Otten GR, Yu D, Mandl CW, Mason PW, Dormitzer PR, Ulmer JB, Geall AJ.

Adv Genet. 2015;89:179-233. doi: 10.1016/bs.adgen.2014.10.005. Epub 2014 Dec 4.

PMID:
25620012
23.

Protectome analysis: a new selective bioinformatics tool for bacterial vaccine candidate discovery.

Altindis E, Cozzi R, Di Palo B, Necchi F, Mishra RP, Fontana MR, Soriani M, Bagnoli F, Maione D, Grandi G, Liberatori S.

Mol Cell Proteomics. 2015 Feb;14(2):418-29. doi: 10.1074/mcp.M114.039362. Epub 2014 Nov 3.

24.

Apo, Zn2+-bound and Mn2+-bound structures reveal ligand-binding properties of SitA from the pathogen Staphylococcus pseudintermedius.

Abate F, Malito E, Cozzi R, Lo Surdo P, Maione D, Bottomley MJ.

Biosci Rep. 2014 Nov 24;34(6):e00154. doi: 10.1042/BSR20140088.

25.

Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline.

Da Cunha V, Davies MR, Douarre PE, Rosinski-Chupin I, Margarit I, Spinali S, Perkins T, Lechat P, Dmytruk N, Sauvage E, Ma L, Romi B, Tichit M, Lopez-Sanchez MJ, Descorps-Declere S, Souche E, Buchrieser C, Trieu-Cuot P, Moszer I, Clermont D, Maione D, Bouchier C, McMillan DJ, Parkhill J, Telford JL, Dougan G, Walker MJ; DEVANI Consortium, Holden MTG, Poyart C, Glaser P.

Nat Commun. 2014 Aug 4;5:4544. doi: 10.1038/ncomms5544. Erratum in: Nat Commun. 2015;6:6108.

26.

Acidic pH strongly enhances in vitro biofilm formation by a subset of hypervirulent ST-17 Streptococcus agalactiae strains.

D'Urzo N, Martinelli M, Pezzicoli A, De Cesare V, Pinto V, Margarit I, Telford JL, Maione D; Members of the DEVANI Study Group.

Appl Environ Microbiol. 2014 Apr;80(7):2176-85. doi: 10.1128/AEM.03627-13. Epub 2014 Jan 31.

27.

Rapidly produced SAM(®) vaccine against H7N9 influenza is immunogenic in mice.

Hekele A, Bertholet S, Archer J, Gibson DG, Palladino G, Brito LA, Otten GR, Brazzoli M, Buccato S, Bonci A, Casini D, Maione D, Qi ZQ, Gill JE, Caiazza NC, Urano J, Hubby B, Gao GF, Shu Y, De Gregorio E, Mandl CW, Mason PW, Settembre EC, Ulmer JB, Craig Venter J, Dormitzer PR, Rappuoli R, Geall AJ.

Emerg Microbes Infect. 2013 Aug;2(8):e52. doi: 10.1038/emi.2013.54. Epub 2013 Aug 14.

28.

VO2 kinetics in supra-anaerobic threshold constant tests allow the visualization and quantification of the O2 saving after cytochrome c oxidase inhibition by aerobic training or nitrate administration.

Maione D, Cicero AF, Bacchelli S, Cosentino E, Degli Esposti D, Senaldi R, Strocchi E, D'Addato S, Borghi C.

Physiol Res. 2013;62(6):671-9. Epub 2013 Jul 17.

29.

Understanding the molecular determinants driving the immunological specificity of the protective pilus 2a backbone protein of group B streptococcus.

Nuccitelli A, Rinaudo CD, Brogioni B, Cozzi R, Ferrer-Navarro M, Yero D, Telford JL, Grandi G, Daura X, Zacharias M, Maione D.

PLoS Comput Biol. 2013;9(6):e1003115. doi: 10.1371/journal.pcbi.1003115. Epub 2013 Jun 27.

30.

Protective efficacy induced by recombinant Clostridium difficile toxin fragments.

Leuzzi R, Spencer J, Buckley A, Brettoni C, Martinelli M, Tulli L, Marchi S, Luzzi E, Irvine J, Candlish D, Veggi D, Pansegrau W, Fiaschi L, Savino S, Swennen E, Cakici O, Oviedo-Orta E, Giraldi M, Baudner B, D'Urzo N, Maione D, Soriani M, Rappuoli R, Pizza M, Douce GR, Scarselli M.

Infect Immun. 2013 Aug;81(8):2851-60. doi: 10.1128/IAI.01341-12. Epub 2013 May 28.

31.

Group B Streptococcus pilus sortase regulation: a single mutation in the lid region induces pilin protein polymerization in vitro.

Cozzi R, Zerbini F, Assfalg M, D'Onofrio M, Biagini M, Martinelli M, Nuccitelli A, Norais N, Telford JL, Maione D, Rinaudo CD.

FASEB J. 2013 Aug;27(8):3144-54. doi: 10.1096/fj.13-227793. Epub 2013 Apr 30.

PMID:
23631841
32.

High-level intracellular expression of heterologous proteins in Brevibacillus choshinensis SP3 under the control of a xylose inducible promoter.

D'Urzo N, Martinelli M, Nenci C, Brettoni C, Telford JL, Maione D.

Microb Cell Fact. 2013 Feb 1;12:12. doi: 10.1186/1475-2859-12-12.

33.

Capsular gene typing of Streptococcus agalactiae compared to serotyping by latex agglutination.

Yao K, Poulsen K, Maione D, Rinaudo CD, Baldassarri L, Telford JL, Sørensen UB; Members of the DEVANI Study Group, Kilian M.

J Clin Microbiol. 2013 Feb;51(2):503-7. doi: 10.1128/JCM.02417-12. Epub 2012 Nov 28.

34.

Structural basis for group B streptococcus pilus 1 sortases C regulation and specificity.

Cozzi R, Prigozhin D, Rosini R, Abate F, Bottomley MJ, Grandi G, Telford JL, Rinaudo CD, Maione D, Alber T.

PLoS One. 2012;7(11):e49048. doi: 10.1371/journal.pone.0049048. Epub 2012 Nov 8.

35.

The structure of Clostridium difficile toxin A glucosyltransferase domain bound to Mn2+ and UDP provides insights into glucosyltransferase activity and product release.

D'Urzo N, Malito E, Biancucci M, Bottomley MJ, Maione D, Scarselli M, Martinelli M.

FEBS J. 2012 Sep;279(17):3085-97. doi: 10.1111/j.1742-4658.2012.08688.x. Epub 2012 Jul 23.

36.

A new flow-cytometry-based opsonophagocytosis assay for the rapid measurement of functional antibody levels against Group B Streptococcus.

Fabbrini M, Sammicheli C, Margarit I, Maione D, Grandi G, Giuliani MM, Mori E, Nuti S.

J Immunol Methods. 2012 Apr 30;378(1-2):11-9. doi: 10.1016/j.jim.2012.01.011. Epub 2012 Jan 30.

37.

New insights into the role of the glutamic acid of the E-box motif in group B Streptococcus pilus 2a assembly.

Cozzi R, Nuccitelli A, D'Onofrio M, Necchi F, Rosini R, Zerbini F, Biagini M, Norais N, Beier C, Telford JL, Grandi G, Assfalg M, Zacharias M, Maione D, Rinaudo CD.

FASEB J. 2012 May;26(5):2008-18. doi: 10.1096/fj.11-196378. Epub 2012 Jan 17.

PMID:
22253480
38.

Sortase A substrate specificity in GBS pilus 2a cell wall anchoring.

Necchi F, Nardi-Dei V, Biagini M, Assfalg M, Nuccitelli A, Cozzi R, Norais N, Telford JL, Rinaudo CD, Grandi G, Maione D.

PLoS One. 2011;6(10):e25300. doi: 10.1371/journal.pone.0025300. Epub 2011 Oct 4.

39.

Structure-based approach to rationally design a chimeric protein for an effective vaccine against Group B Streptococcus infections.

Nuccitelli A, Cozzi R, Gourlay LJ, Donnarumma D, Necchi F, Norais N, Telford JL, Rappuoli R, Bolognesi M, Maione D, Grandi G, Rinaudo CD.

Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10278-83. doi: 10.1073/pnas.1106590108. Epub 2011 May 18.

40.

Structure analysis and site-directed mutagenesis of defined key residues and motives for pilus-related sortase C1 in group B Streptococcus.

Cozzi R, Malito E, Nuccitelli A, D'Onofrio M, Martinelli M, Ferlenghi I, Grandi G, Telford JL, Maione D, Rinaudo CD.

FASEB J. 2011 Jun;25(6):1874-86. doi: 10.1096/fj.10-174797. Epub 2011 Feb 25.

PMID:
21357525
41.

Simple sequence repeats and genome plasticity in Streptococcus agalactiae.

Janulczyk R, Masignani V, Maione D, Tettelin H, Grandi G, Telford JL.

J Bacteriol. 2010 Aug;192(15):3990-4000. doi: 10.1128/JB.01465-09. Epub 2010 May 21.

42.

Specific involvement of pilus type 2a in biofilm formation in group B Streptococcus.

Rinaudo CD, Rosini R, Galeotti CL, Berti F, Necchi F, Reguzzi V, Ghezzo C, Telford JL, Grandi G, Maione D.

PLoS One. 2010 Feb 15;5(2):e9216. doi: 10.1371/journal.pone.0009216.

43.

Toll-like receptor 2 dependent immunogenicity of glycoconjugate vaccines containing chemically derived zwitterionic polysaccharides.

Gallorini S, Berti F, Mancuso G, Cozzi R, Tortoli M, Volpini G, Telford JL, Beninati C, Maione D, Wack A.

Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17481-6. doi: 10.1073/pnas.0903313106. Epub 2009 Sep 29.

44.

BibA induces opsonizing antibodies conferring in vivo protection against group B Streptococcus.

Santi I, Maione D, Galeotti CL, Grandi G, Telford JL, Soriani M.

J Infect Dis. 2009 Aug 15;200(4):564-70. doi: 10.1086/603540.

PMID:
19586417
45.

Surfome analysis as a fast track to vaccine discovery: identification of a novel protective antigen for Group B Streptococcus hypervirulent strain COH1.

Doro F, Liberatori S, Rodríguez-Ortega MJ, Rinaudo CD, Rosini R, Mora M, Scarselli M, Altindis E, D'Aurizio R, Stella M, Margarit I, Maione D, Telford JL, Norais N, Grandi G.

Mol Cell Proteomics. 2009 Jul;8(7):1728-37. doi: 10.1074/mcp.M800486-MCP200. Epub 2009 Apr 28.

46.

Preventing bacterial infections with pilus-based vaccines: the group B streptococcus paradigm.

Margarit I, Rinaudo CD, Galeotti CL, Maione D, Ghezzo C, Buttazzoni E, Rosini R, Runci Y, Mora M, Buccato S, Pagani M, Tresoldi E, Berardi A, Creti R, Baker CJ, Telford JL, Grandi G.

J Infect Dis. 2009 Jan 1;199(1):108-15. doi: 10.1086/595564.

PMID:
19086816
47.

Sortase A utilizes an ancillary protein anchor for efficient cell wall anchoring of pili in Streptococcus agalactiae.

Nobbs AH, Rosini R, Rinaudo CD, Maione D, Grandi G, Telford JL.

Infect Immun. 2008 Aug;76(8):3550-60. doi: 10.1128/IAI.01613-07. Epub 2008 Jun 9.

48.

Invariant NKT cells sustain specific B cell responses and memory.

Galli G, Pittoni P, Tonti E, Malzone C, Uematsu Y, Tortoli M, Maione D, Volpini G, Finco O, Nuti S, Tavarini S, Dellabona P, Rappuoli R, Casorati G, Abrignani S.

Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):3984-9. Epub 2007 Feb 27.

49.

Use of Lactococcus lactis expressing pili from group B Streptococcus as a broad-coverage vaccine against streptococcal disease.

Buccato S, Maione D, Rinaudo CD, Volpini G, Taddei AR, Rosini R, Telford JL, Grandi G, Margarit I.

J Infect Dis. 2006 Aug 1;194(3):331-40. Epub 2006 Jun 30.

PMID:
16826481
50.

Identification of novel genomic islands coding for antigenic pilus-like structures in Streptococcus agalactiae.

Rosini R, Rinaudo CD, Soriani M, Lauer P, Mora M, Maione D, Taddei A, Santi I, Ghezzo C, Brettoni C, Buccato S, Margarit I, Grandi G, Telford JL.

Mol Microbiol. 2006 Jul;61(1):126-41.

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