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Items: 47


The R941L mutation in MYH14 disrupts mitochondrial fission and associates with peripheral neuropathy.

Almutawa W, Smith C, Sabouny R, Smit RB, Zhao T, Wong R, Lee-Glover L, Desrochers-Goyette J, Ilamathi HS; Care4Rare Canada Consortium, Suchowersky O, Germain M, Mains PE, Parboosingh JS, Pfeffer G, Innes AM, Shutt TE.

EBioMedicine. 2019 Jul;45:379-392. doi: 10.1016/j.ebiom.2019.06.018. Epub 2019 Jun 21.


Tissue-Specific Functions of fem-2/PP2c Phosphatase and fhod-1/formin During Caenorhabditis elegans Embryonic Morphogenesis.

Refai O, Smit RB, Votra S, Pruyne D, Mains PE.

G3 (Bethesda). 2018 Jul 2;8(7):2277-2290. doi: 10.1534/g3.118.200274.


A Strategy To Isolate Modifiers of Caenorhabditis elegans Lethal Mutations: Investigating the Endoderm Specifying Ability of the Intestinal Differentiation GATA Factor ELT-2.

Wiesenfahrt T, Duanmu J, Snider F, Moerman D, Au V, Li-Leger E, Flibotte S, Parker DM, Marshall CJ, Nishimura EO, Mains PE, McGhee JD.

G3 (Bethesda). 2018 May 4;8(5):1425-1437. doi: 10.1534/g3.118.200079.


Identification of ABC transporters acting in vitamin B12 metabolism in Caenorhabditis elegans.

McDonald MK, Fritz JA, Jia D, Scheuchner D, Snyder FF, Stanislaus A, Curle J, Li L, Stabler SP, Allen RH, Mains PE, Gravel RA.

Mol Genet Metab. 2017 Dec;122(4):160-171. doi: 10.1016/j.ymgme.2017.11.002. Epub 2017 Nov 11.


Regulation of the MEI-1/MEI-2 Microtubule-Severing Katanin Complex in Early Caenorhabditis elegans Development.

Beard SM, Smit RB, Chan BG, Mains PE.

G3 (Bethesda). 2016 Oct 13;6(10):3257-3268. doi: 10.1534/g3.116.031666.


The Rho guanine exchange factor RHGF-2 acts through the Rho-binding kinase LET-502 to mediate embryonic elongation in C. elegans.

Chan BG, Rocheleau SK, Smit RB, Mains PE.

Dev Biol. 2015 Sep 15;405(2):250-9. doi: 10.1016/j.ydbio.2015.07.010. Epub 2015 Jul 15.


The asymmetry of female meiosis reduces the frequency of inheritance of unpaired chromosomes.

Cortes DB, McNally KL, Mains PE, McNally FJ.

Elife. 2015 Apr 7;4:e06056. doi: 10.7554/eLife.06056.


The role of the formin gene fhod-1 in C. elegans embryonic morphogenesis.

Vanneste CA, Pruyne D, Mains PE.

Worm. 2013 Jul 1;2(3):e25040. doi: 10.4161/worm.25040. Epub 2013 May 16.


Caenorhabditis elegans oocyte meiotic spindle pole assembly requires microtubule severing and the calponin homology domain protein ASPM-1.

Connolly AA, Osterberg V, Christensen S, Price M, Lu C, Chicas-Cruz K, Lockery S, Mains PE, Bowerman B.

Mol Biol Cell. 2014 Apr;25(8):1298-311. doi: 10.1091/mbc.E13-11-0687. Epub 2014 Feb 19.


Katanin maintains meiotic metaphase chromosome alignment and spindle structure in vivo and has multiple effects on microtubules in vitro.

McNally K, Berg E, Cortes DB, Hernandez V, Mains PE, McNally FJ.

Mol Biol Cell. 2014 Apr;25(7):1037-49. doi: 10.1091/mbc.E13-12-0764. Epub 2014 Feb 5.


Extension of the Caenorhabditis elegans Pharyngeal M1 neuron axon is regulated by multiple mechanisms.

Refai O, Rohs P, Mains PE, Gaudet J.

G3 (Bethesda). 2013 Nov 6;3(11):2015-29. doi: 10.1534/g3.113.008466.


Microtubule severing by the katanin complex is activated by PPFR-1-dependent MEI-1 dephosphorylation.

Gomes JE, Tavernier N, Richaudeau B, Formstecher E, Boulin T, Mains PE, Dumont J, Pintard L.

J Cell Biol. 2013 Aug 5;202(3):431-9. doi: 10.1083/jcb.201304174.


UNC-89 (obscurin) binds to MEL-26, a BTB-domain protein, and affects the function of MEI-1 (katanin) in striated muscle of Caenorhabditis elegans.

Wilson KJ, Qadota H, Mains PE, Benian GM.

Mol Biol Cell. 2012 Jul;23(14):2623-34. doi: 10.1091/mbc.E12-01-0055. Epub 2012 May 23.


Levels of the ubiquitin ligase substrate adaptor MEL-26 are inversely correlated with MEI-1/katanin microtubule-severing activity during both meiosis and mitosis.

Johnson JL, Lu C, Raharjo E, McNally K, McNally FJ, Mains PE.

Dev Biol. 2009 Jun 15;330(2):349-57. doi: 10.1016/j.ydbio.2009.04.004. Epub 2009 Apr 8.


The role of protein phosphatase 4 in regulating microtubule severing in the Caenorhabditis elegans embryo.

Han X, Gomes JE, Birmingham CL, Pintard L, Sugimoto A, Mains PE.

Genetics. 2009 Mar;181(3):933-43. doi: 10.1534/genetics.108.096016. Epub 2008 Dec 15.


The Caenorhabditis elegans ing-3 gene regulates ionizing radiation-induced germ-cell apoptosis in a p53-associated pathway.

Luo J, Shah S, Riabowol K, Mains PE.

Genetics. 2009 Feb;181(2):473-82. doi: 10.1534/genetics.107.080515. Epub 2008 Nov 17.


The BTB protein MEL-26 promotes cytokinesis in C. elegans by a CUL-3-independent mechanism.

Luke-Glaser S, Pintard L, Lu C, Mains PE, Peter M.

Curr Biol. 2005 Sep 20;15(18):1605-15.


Squeezing an egg into a worm: C. elegans embryonic morphogenesis.

Piekny AJ, Mains PE.

ScientificWorldJournal. 2003 Dec 18;3:1370-81. Review.


The mbk-2 kinase is required for inactivation of MEI-1/katanin in the one-cell Caenorhabditis elegans embryo.

Quintin S, Mains PE, Zinke A, Hyman AA.

EMBO Rep. 2003 Dec;4(12):1175-81. Epub 2003 Nov 21.


The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase.

Pintard L, Willis JH, Willems A, Johnson JL, Srayko M, Kurz T, Glaser S, Mains PE, Tyers M, Bowerman B, Peter M.

Nature. 2003 Sep 18;425(6955):311-6. Epub 2003 Sep 3.


MEI-1/MEI-2 katanin-like microtubule severing activity is required for Caenorhabditis elegans meiosis.

Srayko M, Buster DW, Bazirgan OA, McNally FJ, Mains PE.

Genes Dev. 2000 May 1;14(9):1072-84.


Embryonic development in Caenorhabditis elegans.

Mains PE.

Results Probl Cell Differ. 1992;18:49-90. Review. No abstract available.


Mutations affecting the meiotic and mitotic divisions of the early Caenorhabditis elegans embryo.

Mains PE, Kemphues KJ, Sprunger SA, Sulston IA, Wood WB.

Genetics. 1990 Nov;126(3):593-605.


Nonhomologous pairing in mice heterozygous for a t haplotype can produce recombinant chromosomes with duplications and deletions.

Sarvetnick N, Fox HS, Mann E, Mains PE, Elliott RW, Silver LM.

Genetics. 1986 Jul;113(3):723-34.


Genetic analysis of the proximal portion of the mouse t complex: evidence for a second inversion within t haplotypes.

Herrmann B, Bućan M, Mains PE, Frischauf AM, Silver LM, Lehrach H.

Cell. 1986 Feb 14;44(3):469-76.


LPS-nonresponsive variants of mouse B cell lymphoma, 70Z/3: isolation and characterization.

Mains PE, Sibley CH.

Somatic Cell Genet. 1983 Nov;9(6):699-720.


Control of IgM synthesis in the murine pre-B cell line, 70Z/3'.

Mains PE, Sibley CH.

J Immunol. 1982 Apr;128(4):1664-70.


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