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Ribosomal Formation of Thioamide Bond in Polypeptide Synthesis.

Maini R, Kimura H, Takatsuji R, Katoh T, Goto Y, Suga H.

J Am Chem Soc. 2019 Dec 9. doi: 10.1021/jacs.9b11097. [Epub ahead of print]


Meta-Analysis Evaluating Outcomes of Surgical Left Atrial Appendage Occlusion During Cardiac Surgery.

Ibrahim AM, Tandan N, Koester C, Al-Akchar M, Bhandari B, Botchway A, Abdelkarim J, Maini R, Labedi M.

Am J Cardiol. 2019 Oct 15;124(8):1218-1225. doi: 10.1016/j.amjcard.2019.07.032. Epub 2019 Aug 1.


Refractive Laser-Assisted Cataract Surgery vs. Conventional Manual Surgery: Comparing Efficacy and Safety in 3144 Eyes.

Nithianandan H, Jegatheeswaran V, Dalal V, Arshinoff SA, Maini R, Nazemi F, Le T, Tam ES, Somani S.

Am J Ophthalmol. 2019 Apr 19. pii: S0002-9394(19)30185-0. doi: 10.1016/j.ajo.2019.04.010. [Epub ahead of print]


The juxtamembrane linker in neutral sphingomyelinase-2 functions as an intramolecular allosteric switch that activates the enzyme.

Shanbhogue P, Hoffmann RM, Airola MV, Maini R, Hamelin DJ, Garcia-Diaz M, Burke JE, Hannun YA.

J Biol Chem. 2019 May 3;294(18):7488-7502. doi: 10.1074/jbc.RA118.007288. Epub 2019 Mar 19.


Evaluation of a questionnaire to measure parent/carer and child/young person experience of NHS epilepsy services.

Maini R, Kirkpatrick M, McCafferty A, Dunkley C, Ogston S, Williams F.

Seizure. 2018 Dec;63:71-78. doi: 10.1016/j.seizure.2018.11.002. Epub 2018 Nov 2.


Persistent Underrepresentation of Kidney Disease in Randomized, Controlled Trials of Cardiovascular Disease in the Contemporary Era.

Maini R, Wong DB, Addison D, Chiang E, Weisbord SD, Jneid H.

J Am Soc Nephrol. 2018 Dec;29(12):2782-2786. doi: 10.1681/ASN.2018070674. Epub 2018 Nov 2. No abstract available.


Performance-based financing versus improving salary payments to workers: insights from the Democratic Republic of Congo.

Maini R, Mounier-Jack S, Borghi J.

BMJ Glob Health. 2018 Sep 25;3(5):e000958. doi: 10.1136/bmjgh-2018-000958. eCollection 2018. No abstract available.


Physiologic assessment of moderate coronary lesions: a step towards complete revascularization in coronary artery bypass grafting.

Moscona JC, Stencel JD, Milligan G, Salmon C, Maini R, Katigbak P, Saleh Q, Nelson R, Srivastav S, Mogabgab O, Samson R, Le Jemtel T.

Ann Transl Med. 2018 Aug;6(15):300. doi: 10.21037/atm.2018.06.31.


Knowing What We Know - Reflections on the Development of Technical Guidance for Loss Data for the Sendai Framework for Disaster Risk Reduction.

Clarke L, Blanchard K, Maini R, Radu A, Eltinay N, Zaidi Z, Murray V.

PLoS Curr. 2018 Aug 2;10. pii: ecurrents.dis.537bd80d1037a2ffde67d66c604d2a78. doi: 10.1371/currents.dis.537bd80d1037a2ffde67d66c604d2a78. Erratum in: PLoS Curr. 2018 Sep 24;10:.


Pooled diagnostic accuracy of resting distal to aortic coronary pressure referenced to fractional flow reserve: The importance of resting coronary physiology.

Maini R, Moscona J, Sidhu G, Katigbak P, Fernandez C, Irimpen A, Mogabgab O, Ward C, Samson R, LeJemtel T.

J Interv Cardiol. 2018 Oct;31(5):588-598. doi: 10.1111/joic.12517. Epub 2018 Apr 29. Review.


The Incidence, Risk Factors, and Chronobiology of Acute Myocardial Infarction Ten Years After Hurricane Katrina.

Moscona JC, Peters MN, Maini R, Katigbak P, Deere B, Gonzales H, Westley C, Baydoun H, Yadav K, Ters P, Jabbar A, Boulad A, Mahata I, Gadiraju TV, Nelson R, Srivastav S, Irimpen A.

Disaster Med Public Health Prep. 2019 Apr;13(2):217-222. doi: 10.1017/dmp.2018.22. Epub 2018 Apr 12.


A Double Whammy: Severe Aortic Stenosis and Cocaine Overwhelm the Mitral Valve.

Maini R, Lim J, Liu J, Birnbaum I, Mirza F, Lakkis N, Hamzeh I.

Methodist Debakey Cardiovasc J. 2018 Jan-Mar;14(1):63-65. doi: 10.14797/mdcj-14-1-63.


How to and how not to develop a theory of change to evaluate a complex intervention: reflections on an experience in the Democratic Republic of Congo.

Maini R, Mounier-Jack S, Borghi J.

BMJ Glob Health. 2018 Jan 3;3(1):e000617. doi: 10.1136/bmjgh-2017-000617. eCollection 2018. Review.


Instantaneous wave-free ratio as an alternative to fractional flow reserve in assessment of moderate coronary stenoses: A meta-analysis of diagnostic accuracy studies.

Maini R, Moscona J, Katigbak P, Fernandez C, Sidhu G, Saleh Q, Irimpen A, Samson R, LeJemtel T.

Cardiovasc Revasc Med. 2018 Jul - Aug;19(5 Pt B):613-620. doi: 10.1016/j.carrev.2017.12.014. Epub 2017 Dec 27. Review.


Monitoring progress towards planetary health.

Maini R, Law R, Duque F 3rd, Balboa G, Noda H, Nakamura S, Murray V.

BMJ. 2017 Dec 7;359:j5279. doi: 10.1136/bmj.j5279. No abstract available.


Incorporation of Phosphorylated Tyrosine into Proteins: In Vitro Translation and Study of Phosphorylated IκB-α and Its Interaction with NF-κB.

Chen S, Maini R, Bai X, Nangreave RC, Dedkova LM, Hecht SM.

J Am Chem Soc. 2017 Oct 11;139(40):14098-14108. doi: 10.1021/jacs.7b05168. Epub 2017 Sep 27.


Structure of human nSMase2 reveals an interdomain allosteric activation mechanism for ceramide generation.

Airola MV, Shanbhogue P, Shamseddine AA, Guja KE, Senkal CE, Maini R, Bartke N, Wu BX, Obeid LM, Garcia-Diaz M, Hannun YA.

Proc Natl Acad Sci U S A. 2017 Jul 11;114(28):E5549-E5558. doi: 10.1073/pnas.1705134114. Epub 2017 Jun 26.


Cardiac MRI as a useful tool to differentiate tumor and thrombus.

Maini R, Gadiraju TV, Jabbar A, Danrad R, Sweeney A.

Int J Cardiovasc Imaging. 2017 Nov;33(11):1795-1796. doi: 10.1007/s10554-017-1172-5. Epub 2017 May 22. No abstract available.


A cross-sectional study of the income sources of primary care health workers in the Democratic Republic of Congo.

Maini R, Hotchkiss DR, Borghi J.

Hum Resour Health. 2017 Feb 20;15(1):17. doi: 10.1186/s12960-017-0185-4.


Ribosome-mediated synthesis of natural product-like peptides via cell-free translation.

Maini R, Umemoto S, Suga H.

Curr Opin Chem Biol. 2016 Oct;34:44-52. doi: 10.1016/j.cbpa.2016.06.006. Epub 2016 Jun 24. Review.


James Thomas (Tom) Scott 1926-2015.

Maini R.

Rheumatology (Oxford). 2016 Mar;55(3):592-3. No abstract available.


Synthesis of fluorescent dipeptidomimetics and their ribosomal incorporation into green fluorescent protein.

Roy Chowdhury S, Maini R, Dedkova LM, Hecht SM.

Bioorg Med Chem Lett. 2015 Nov 1;25(21):4715-4718. doi: 10.1016/j.bmcl.2015.08.073. Epub 2015 Aug 29.


Ribosome-Mediated Incorporation of Dipeptides and Dipeptide Analogues into Proteins in Vitro.

Maini R, Dedkova LM, Paul R, Madathil MM, Chowdhury SR, Chen S, Hecht SM.

J Am Chem Soc. 2015 Sep 9;137(35):11206-9. doi: 10.1021/jacs.5b03135. Epub 2015 Aug 31.


Clinical features of patients isolated for suspected Ebola virus disease at Connaught Hospital, Freetown, Sierra Leone: a retrospective cohort study.

Lado M, Walker NF, Baker P, Haroon S, Brown CS, Youkee D, Studd N, Kessete Q, Maini R, Boyles T, Hanciles E, Wurie A, Kamara TB, Johnson O, Leather AJM.

Lancet Infect Dis. 2015 Sep;15(9):1024-1033. doi: 10.1016/S1473-3099(15)00137-1. Epub 2015 Jul 23.


Perspectives From Masters in Rheumatology and Autoimmunity: Can We Get Closer to a Cure for Rheumatoid Arthritis?

Feldmann M, Maini RN.

Arthritis Rheumatol. 2015 Sep;67(9):2283-91. doi: 10.1002/art.39269. No abstract available.


Protein Synthesis with Ribosomes Selected for the Incorporation of β-Amino Acids.

Maini R, Chowdhury SR, Dedkova LM, Roy B, Daskalova SM, Paul R, Chen S, Hecht SM.

Biochemistry. 2015 Jun 16;54(23):3694-706. doi: 10.1021/acs.biochem.5b00389. Epub 2015 Jun 2.


Isolated perforation of left coronary cusp after blunt chest trauma.

Maini R, Dadu RT, Addison D, Cunningham L, Hamzeh I, Wall M Jr, Lakkis N, Tabbaa R.

Case Rep Cardiol. 2015;2015:235629. doi: 10.1155/2015/235629. Epub 2015 Feb 23.


Picking up the bill - improving health-care utilisation in the Democratic Republic of Congo through user fee subsidisation: a before and after study.

Maini R, Van den Bergh R, van Griensven J, Tayler-Smith K, Ousley J, Carter D, Mhatre S, Ho L, Zachariah R.

BMC Health Serv Res. 2014 Nov 5;14:504. doi: 10.1186/s12913-014-0504-6.


Increasing Pneumocystis pneumonia, England, UK, 2000-2010.

Maini R, Henderson KL, Sheridan EA, Lamagni T, Nichols G, Delpech V, Phin N.

Emerg Infect Dis. 2013 Mar;19(3):386-92. doi: 10.3201/eid1903.121151.


Incorporation of β-amino acids into dihydrofolate reductase by ribosomes having modifications in the peptidyltransferase center.

Maini R, Nguyen DT, Chen S, Dedkova LM, Chowdhury SR, Alcala-Torano R, Hecht SM.

Bioorg Med Chem. 2013 Mar 1;21(5):1088-96. doi: 10.1016/j.bmc.2013.01.002. Epub 2013 Jan 9.


Travel-associated Legionnaires disease in residents from England and Wales travelling to Corfu, Greece, August to October 2011.

Maini R, Naik F, Harrison Tg, Mentasti M, Spala G, Velonakis E, Hadjichristodoulou C, de Jong B, Vatopoulos A, Phin N.

Euro Surveill. 2012 Aug 9;17(32). pii: 20240.


Synthesis and biological activities of topopyrones.

Zaleski PA, Maini R, Leiris SJ, Elban MA, Hecht SM.

J Nat Prod. 2012 Apr 27;75(4):577-85. doi: 10.1021/np200777z. Epub 2012 Mar 30.


Outcome of cataract surgery in Nigeria: visual acuity, autorefraction, and optimal intraocular lens powers--results from the Nigeria national survey.

Imam AU, Gilbert CE, Sivasubramaniam S, Murthy GV, Maini R, Rabiu MM; Nigeria National Blindness and Visual Impairment Study Group.

Ophthalmology. 2011 Apr;118(4):719-24. doi: 10.1016/j.ophtha.2010.08.025. Epub 2010 Nov 4.


Anti-TNF therapy, from rationale to standard of care: what lessons has it taught us?

Feldmann M, Maini RN.

J Immunol. 2010 Jul 15;185(2):791-4. doi: 10.4049/jimmunol.1090051.


Anti-TNF therapy from the bench to the clinic: a paradigm of translational research.

Maini RN.

Clin Med (Lond). 2010 Apr;10(2):161-2. No abstract available.


Introducing Arthritis Research & Therapy's 10th anniversary issue, 'The Scientific Basis of Rheumatology: A Decade of Progress'.

Hrynaszkiewicz I, Lipsky PE, Maini RN.

Arthritis Res Ther. 2008;10(5):119. doi: 10.1186/ar2522. Epub 2008 Oct 10. No abstract available.


Radiographic changes in rheumatoid arthritis patients attaining different disease activity states with methotrexate monotherapy and infliximab plus methotrexate: the impacts of remission and tumour necrosis factor blockade.

Smolen JS, Han C, van der Heijde DM, Emery P, Bathon JM, Keystone E, Maini RN, Kalden JR, Aletaha D, Baker D, Han J, Bala M, St Clair EW; Active-Controlled Study of Patients Receiving Infliximab for the Treatment of Rheumatoid Arthritis of Early Onset (ASPIRE) Study Group.

Ann Rheum Dis. 2009 Jun;68(6):823-7. doi: 10.1136/ard.2008.090019. Epub 2008 Jul 1. Erratum in: Ann Rheum Dis. 2011 Aug;70(8):1519.


Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha.

Elliot MJ, Maini RN, Feldmann M, Long-Fox A, Charles P, Katasikis P, Brennan FM, Bijl H, Ghrayeb J, Woody JN.

Arthritis Rheum. 2008 Feb;58(2 Suppl):S92-S101. doi: 10.1002/art.23362.


The pitfalls in the development of biologic therapy.

Maini RN, Feldmann M.

Nat Clin Pract Rheumatol. 2007 Jan;3(1):1. No abstract available.


Double-blind randomized controlled clinical trial of the interleukin-6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexate.

Maini RN, Taylor PC, Szechinski J, Pavelka K, Bröll J, Balint G, Emery P, Raemen F, Petersen J, Smolen J, Thomson D, Kishimoto T; CHARISMA Study Group.

Arthritis Rheum. 2006 Sep;54(9):2817-29. Erratum in: Arthritis Rheum. 2008 Mar;58(3):887.


Interleukin-6: a new therapeutic target.

Smolen JS, Maini RN.

Arthritis Res Ther. 2006;8 Suppl 2:S5. Epub 2006 Jul 28. Review. Erratum in: Arthritis Res Ther. 2006;8(6):407.


A survey of excimer laser use among consultant ophthalmologists in United Kingdom.

Kashani S, De Silva DJ, Aslam S, Maini R.

Eye (Lond). 2007 Feb;21(2):279-81. Epub 2006 Jul 21. No abstract available.


The management of severe sclerokeratitis following corneal transplantation surgery.

Maini R, Dart JK.

Br J Ophthalmol. 2006 Jul;90(7):918-20. No abstract available.


Topical steroid and antibiotic combination therapy in red eye conditions.

Bradshaw SE, Shankar P, Maini R.

Br J Gen Pract. 2006 Apr;56(525):304. No abstract available.


Ocular trauma caused by a loose slip-lock cannula during corneal hydration.

Bradshaw SE, Shankar P, Maini R, Ragheb S.

Eye (Lond). 2006 Dec;20(12):1432-4. Epub 2006 Mar 10. No abstract available.


Infliximab treatment maintains employability in patients with early rheumatoid arthritis.

Smolen JS, Han C, van der Heijde D, Emery P, Bathon JM, Keystone E, Kalden JR, Schiff M, Bala M, Baker D, Han J, Maini RN, St Clair EW.

Arthritis Rheum. 2006 Mar;54(3):716-22.


Predictors of joint damage in patients with early rheumatoid arthritis treated with high-dose methotrexate with or without concomitant infliximab: results from the ASPIRE trial.

Smolen JS, Van Der Heijde DM, St Clair EW, Emery P, Bathon JM, Keystone E, Maini RN, Kalden JR, Schiff M, Baker D, Han C, Han J, Bala M; Active-Controlled Study of Patients Receiving Infliximab for the Treatment of Rheumatoid Arthritis of Early Onset (ASPIRE) Study Group.

Arthritis Rheum. 2006 Mar;54(3):702-10.


Anti-TNF therapy: where have we got to in 2005?

Feldmann M, Brennan FM, Foxwell BM, Taylor PC, Williams RO, Maini RN.

J Autoimmun. 2005;25 Suppl:26-8. Epub 2005 Nov 2. Review.


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