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Items: 27

1.

Positioning High-Throughput CETSA in Early Drug Discovery through Screening against B-Raf and PARP1.

Shaw J, Dale I, Hemsley P, Leach L, Dekki N, Orme JP, Talbot V, Narvaez AJ, Bista M, Martinez Molina D, Dabrowski M, Main MJ, Gianni D.

SLAS Discov. 2019 Feb;24(2):121-132. doi: 10.1177/2472555218813332. Epub 2018 Dec 13.

2.

Randomized study of the safety and pharmacodynamics of inhaled interleukin-13 monoclonal antibody fragment VR942.

Burgess G, Boyce M, Jones M, Larsson L, Main MJ, Morgan F, Phillips P, Scrimgeour A, Strimenopoulou F, Vajjah P, Zamacona M, Palframan R.

EBioMedicine. 2018 Sep;35:67-75. doi: 10.1016/j.ebiom.2018.07.035. Epub 2018 Aug 23.

3.

Microwave-assisted activation and modulator removal in zirconium MOFs for buffer-free CWA hydrolysis.

Kalinovskyy Y, Cooper NJ, Main MJ, Holder SJ, Blight BA.

Dalton Trans. 2017 Nov 21;46(45):15704-15709. doi: 10.1039/c7dt03616g.

PMID:
29094739
4.

Poly High Internal Phase Emulsion for the Immobilization of Chemical Warfare Agents.

Wright AJ, Main MJ, Cooper NJ, Blight BA, Holder SJ.

ACS Appl Mater Interfaces. 2017 Sep 20;9(37):31335-31339. doi: 10.1021/acsami.7b09188. Epub 2017 Sep 5.

PMID:
28853538
5.

Functional expression of the voltage-gated Na⁺-channel Nav1.7 is necessary for EGF-mediated invasion in human non-small cell lung cancer cells.

Campbell TM, Main MJ, Fitzgerald EM.

J Cell Sci. 2013 Nov 1;126(Pt 21):4939-49. doi: 10.1242/jcs.130013. Epub 2013 Aug 28.

6.

Use of escin as a perforating agent on the IonWorks quattro automated electrophysiology platform.

Morton MJ, Main MJ.

J Biomol Screen. 2013 Jan;18(1):128-34. doi: 10.1177/1087057112456599. Epub 2012 Aug 24.

PMID:
22923788
7.

Heterologous expression and functional analysis of rat Nav1.8 (SNS) voltage-gated sodium channels in the dorsal root ganglion neuroblastoma cell line ND7-23.

John VH, Main MJ, Powell AJ, Gladwell ZM, Hick C, Sidhu HS, Clare JJ, Tate S, Trezise DJ.

Neuropharmacology. 2004 Mar;46(3):425-38.

PMID:
14975698
8.

An industrial perspective on utilizing functional ion channel assays for high throughput screening.

Worley JF 3rd, Main MJ.

Receptors Channels. 2002;8(5-6):269-82. Review.

PMID:
12690955
9.

Fecal calprotectin: validation as a noninvasive measure of bowel inflammation in childhood inflammatory bowel disease.

Bunn SK, Bisset WM, Main MJ, Gray ES, Olson S, Golden BE.

J Pediatr Gastroenterol Nutr. 2001 Jul;33(1):14-22.

PMID:
11479402
10.

Fecal calprotectin as a measure of disease activity in childhood inflammatory bowel disease.

Bunn SK, Bisset WM, Main MJ, Golden BE.

J Pediatr Gastroenterol Nutr. 2001 Feb;32(2):171-7.

PMID:
11321388
11.

The N-terminus of RAMPs is a critical determinant of the glycosylation state and ligand binding of calcitonin receptor-like receptor.

Foord SM, Wise A, Brown J, Main MJ, Fraser NJ.

Biochem Soc Trans. 1999 Aug;27(4):535-9. Review. No abstract available.

PMID:
10917636
12.

Modulation of KCNQ2/3 potassium channels by the novel anticonvulsant retigabine.

Main MJ, Cryan JE, Dupere JR, Cox B, Clare JJ, Burbidge SA.

Mol Pharmacol. 2000 Aug;58(2):253-62.

PMID:
10908292
13.

The effects of oxidizing and cysteine-reactive reagents on the inward rectifier potassium channels Kir2.3 and Kir1.1.

Bannister JP, Young BA, Main MJ, Sivaprasadarao A, Wray D.

Pflugers Arch. 1999 Nov;438(6):868-78.

PMID:
10591077
14.

Calcium sensing properties of the GABA(B) receptor.

Wise A, Green A, Main MJ, Wilson R, Fraser N, Marshall FH.

Neuropharmacology. 1999 Nov;38(11):1647-56.

PMID:
10587080
15.

Multiple amylin receptors arise from receptor activity-modifying protein interaction with the calcitonin receptor gene product.

Christopoulos G, Perry KJ, Morfis M, Tilakaratne N, Gao Y, Fraser NJ, Main MJ, Foord SM, Sexton PM.

Mol Pharmacol. 1999 Jul;56(1):235-42.

PMID:
10385705
16.
17.

The CGRP receptor can couple via pertussis toxin sensitive and insensitive G proteins.

Main MJ, Brown J, Brown S, Fraser NJ, Foord SM.

FEBS Lett. 1998 Dec 11;441(1):6-10.

18.

Heterodimerization is required for the formation of a functional GABA(B) receptor.

White JH, Wise A, Main MJ, Green A, Fraser NJ, Disney GH, Barnes AA, Emson P, Foord SM, Marshall FH.

Nature. 1998 Dec 17;396(6712):679-82.

PMID:
9872316
19.

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor.

McLatchie LM, Fraser NJ, Main MJ, Wise A, Brown J, Thompson N, Solari R, Lee MG, Foord SM.

Nature. 1998 May 28;393(6683):333-9.

PMID:
9620797
21.

The roles of the sodium and calcium current in triggering calcium release from the sarcoplasmic reticulum.

Cannell MB, Grantham CJ, Main MJ, Evans AM.

Ann N Y Acad Sci. 1996 Apr 15;779:443-50. Review. No abstract available.

PMID:
8659860
22.

Comparison of IgG subclasses in foetal serum, maternal serum at delivery and milk in IgA-deficient and control women.

Thom H, Carter PE, Duffty P, Main MJ, Brown S.

Acta Paediatr. 1994 Jul;83(7):687-91.

PMID:
7949795
23.

Fluspirilene block of N-type calcium current in NGF-differentiated PC12 cells.

Grantham CJ, Main MJ, Cannell MB.

Br J Pharmacol. 1994 Feb;111(2):483-8.

24.

Differences in the effects of tachykinin NK1 receptor antagonists: neuronal versus smooth muscle tissues.

Seabrook GR, Main MJ, Razzaque Z, Longmore J.

Eur J Pharmacol. 1993 Nov 30;250(1):125-31.

PMID:
7509748
25.

IgG subclass concentrations and Gm allotypes in IgA-deficient and normal pregnant women.

Thom H, Main MJ, Duffy P, Carter PE.

Exp Clin Immunogenet. 1993;10(3):123-8.

PMID:
8286124
26.

On the change of cardiac action potential with age: a study in dogs.

Bosker H, Drake-Holland AJ, ter Keurs HE, Noble MI, Passingham JE, Pepper JR, Main MJ, Wanless RB.

Cardiovasc Res. 1985 Nov;19(11):674-8.

PMID:
4075357
27.

Mioflazine, a potentially protective drug against ischaemic damage: a study in dogs.

Wood AJ, Isted K, Hynd J, Main MJ, Noble MI, Parker J, Drake-Holland AJ.

Eur Heart J. 1985 Aug;6(8):695-701.

PMID:
4054139

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