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Items: 24


A human liver cell atlas reveals heterogeneity and epithelial progenitors.

Aizarani N, Saviano A, Sagar, Mailly L, Durand S, Herman JS, Pessaux P, Baumert TF, Grün D.

Nature. 2019 Aug;572(7768):199-204. doi: 10.1038/s41586-019-1373-2. Epub 2019 Jul 10.


In vivo combination of human anti-envelope glycoprotein E2 and -Claudin-1 monoclonal antibodies for prevention of hepatitis C virus infection.

Mailly L, Wrensch F, Heydmann L, Fauvelle C, Brignon N, Zeisel MB, Pessaux P, Keck ZY, Schuster C, Fuerst TR, Foung SKH, Baumert TF.

Antiviral Res. 2019 Feb;162:136-141. doi: 10.1016/j.antiviral.2018.12.018. Epub 2018 Dec 30.


Hepatitis B Virus Evasion From Cyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase Sensing in Human Hepatocytes.

Verrier ER, Yim SA, Heydmann L, El Saghire H, Bach C, Turon-Lagot V, Mailly L, Durand SC, Lucifora J, Durantel D, Pessaux P, Manel N, Hirsch I, Zeisel MB, Pochet N, Schuster C, Baumert TF.

Hepatology. 2018 Nov;68(5):1695-1709. doi: 10.1002/hep.30054. Epub 2018 Jul 10.


A protein coevolution method uncovers critical features of the Hepatitis C Virus fusion mechanism.

Douam F, Fusil F, Enguehard M, Dib L, Nadalin F, Schwaller L, Hrebikova G, Mancip J, Mailly L, Montserret R, Ding Q, Maisse C, Carlot E, Xu K, Verhoeyen E, Baumert TF, Ploss A, Carbone A, Cosset FL, Lavillette D.

PLoS Pathog. 2018 Mar 5;14(3):e1006908. doi: 10.1371/journal.ppat.1006908. eCollection 2018 Mar.


Protein kinase D at the Golgi controls NLRP3 inflammasome activation.

Zhang Z, Meszaros G, He WT, Xu Y, de Fatima Magliarelli H, Mailly L, Mihlan M, Liu Y, Puig Gámez M, Goginashvili A, Pasquier A, Bielska O, Neven B, Quartier P, Aebersold R, Baumert TF, Georgel P, Han J, Ricci R.

J Exp Med. 2017 Sep 4;214(9):2671-2693. doi: 10.1084/jem.20162040. Epub 2017 Jul 17.


Detection of the hepatitis B virus (HBV) covalently-closed-circular DNA (cccDNA) in mice transduced with a recombinant AAV-HBV vector.

Lucifora J, Salvetti A, Marniquet X, Mailly L, Testoni B, Fusil F, Inchauspé A, Michelet M, Michel ML, Levrero M, Cortez P, Baumert TF, Cosset FL, Challier C, Zoulim F, Durantel D.

Antiviral Res. 2017 Sep;145:14-19. doi: 10.1016/j.antiviral.2017.07.006. Epub 2017 Jul 11.


Toward novel immunocompetent animal models for hepatitis B virus infection.

Mailly L, Zeisel MB, Baumert TF.

Hepatology. 2017 Sep;66(3):691-693. doi: 10.1002/hep.29249. Epub 2017 Jul 20. No abstract available.


Humanisation of a claudin-1-specific monoclonal antibody for clinical prevention and cure of HCV infection without escape.

Colpitts CC, Tawar RG, Mailly L, Thumann C, Heydmann L, Durand SC, Xiao F, Robinet E, Pessaux P, Zeisel MB, Baumert TF.

Gut. 2018 Apr;67(4):736-745. doi: 10.1136/gutjnl-2016-312577. Epub 2017 Mar 30.


Autotaxin-lysophosphatidic acid receptor signalling regulates hepatitis C virus replication.

Farquhar MJ, Humphreys IS, Rudge SA, Wilson GK, Bhattacharya B, Ciaccia M, Hu K, Zhang Q, Mailly L, Reynolds GM, Ashcroft M, Balfe P, Baumert TF, Roessler S, Wakelam MJO, McKeating JA.

J Hepatol. 2017 May;66(5):919-929. doi: 10.1016/j.jhep.2017.01.009. Epub 2017 Jan 23.


[Locked outside: cure of chronic hepatitis C using an entry inhibitor].

Mailly L, Zeisel MB, Baumert TF.

Med Sci (Paris). 2015 Dec;31(12):1075-7. doi: 10.1051/medsci/20153112009. Epub 2015 Dec 16. French. No abstract available.


Artificial microRNAs against the viral E6 protein provoke apoptosis in HPV positive cancer cells.

Bonetta AC, Mailly L, Robinet E, Travé G, Masson M, Deryckere F.

Biochem Biophys Res Commun. 2015 Oct 2;465(4):658-64. doi: 10.1016/j.bbrc.2015.07.144. Epub 2015 Aug 1.


Clearance of persistent hepatitis C virus infection in humanized mice using a claudin-1-targeting monoclonal antibody.

Mailly L, Xiao F, Lupberger J, Wilson GK, Aubert P, Duong FHT, Calabrese D, Leboeuf C, Fofana I, Thumann C, Bandiera S, Lütgehetmann M, Volz T, Davis C, Harris HJ, Mee CJ, Girardi E, Chane-Woon-Ming B, Ericsson M, Fletcher N, Bartenschlager R, Pessaux P, Vercauteren K, Meuleman P, Villa P, Kaderali L, Pfeffer S, Heim MH, Neunlist M, Zeisel MB, Dandri M, McKeating JA, Robinet E, Baumert TF.

Nat Biotechnol. 2015 May;33(5):549-554. doi: 10.1038/nbt.3179. Epub 2015 Mar 23.


A new HCV mouse model on the block.

Tawar RG, Mailly L, Baumert TF.

Cell Res. 2014 Oct;24(10):1153-4. doi: 10.1038/cr.2014.126. Epub 2014 Sep 26.


Synergy of entry inhibitors with direct-acting antivirals uncovers novel combinations for prevention and treatment of hepatitis C.

Xiao F, Fofana I, Thumann C, Mailly L, Alles R, Robinet E, Meyer N, Schaeffer M, Habersetzer F, Doffoël M, Leyssen P, Neyts J, Zeisel MB, Baumert TF.

Gut. 2015 Mar;64(3):483-94. doi: 10.1136/gutjnl-2013-306155. Epub 2014 May 21.


In vivo proof of concept of adoptive immunotherapy for hepatocellular carcinoma using allogeneic suicide gene-modified killer cells.

Leboeuf C, Mailly L, Wu T, Bour G, Durand S, Brignon N, Ferrand C, Borg C, Tiberghien P, Thimme R, Pessaux P, Marescaux J, Baumert TF, Robinet E.

Mol Ther. 2014 Mar;22(3):634-644. doi: 10.1038/mt.2013.277. Epub 2013 Dec 6.


Genetically humanized mice recapitulate the entire hepatitis C virus life cycle.

Mailly L, Zeisel MB, Baumert TF.

J Hepatol. 2014 Mar;60(3):671-3. doi: 10.1016/j.jhep.2013.10.005. Epub 2013 Oct 12. No abstract available.


Hepatitis C virus infection and related liver disease: the quest for the best animal model.

Mailly L, Robinet E, Meuleman P, Baumert TF, Zeisel MB.

Front Microbiol. 2013 Jul 26;4:213. doi: 10.3389/fmicb.2013.00212. eCollection 2013.


Generation of an adenovirus-parvovirus chimera with enhanced oncolytic potential.

El-Andaloussi N, Bonifati S, Kaufmann JK, Mailly L, Daeffler L, Deryckère F, Nettelbeck DM, Rommelaere J, Marchini A.

J Virol. 2012 Oct;86(19):10418-31. doi: 10.1128/JVI.00848-12. Epub 2012 Jul 11.


Genetically engineered T-cells expressing a ganciclovir-sensitive HSV-tk suicide gene for the prevention of GvHD.

Mailly L, Leboeuf C, Tiberghien P, Baumert T, Robinet E.

Curr Opin Investig Drugs. 2010 May;11(5):559-70. Review.


A novel adenovirus vector for easy cloning in the E3 region downstream of the CMV promoter.

Mailly L, Boulade-Ladame C, Orfanoudakis G, Deryckere F.

Virol J. 2008 Jun 6;5:73. doi: 10.1186/1743-422X-5-73.


Intracellular scFvs against the viral E6 oncoprotein provoke apoptosis in human papillomavirus-positive cancer cells.

Lagrange M, Boulade-Ladame C, Mailly L, Weiss E, Orfanoudakis G, Deryckere F.

Biochem Biophys Res Commun. 2007 Sep 21;361(2):487-92. Epub 2007 Jul 18.


Improved gene delivery to B lymphocytes using a modified adenovirus vector targeting CD21.

Mailly L, Renaut L, Rogée S, Grellier E, D'Halluin JC, Colin M.

Mol Ther. 2006 Aug;14(2):293-304. Epub 2006 Jun 2.


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