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Items: 50

1.

An anti-αVβ3 antibody inhibits coronary artery atherosclerosis in diabetic pigs.

Maile LA, Busby WH, Xi G, Gollahan KP, Flowers W, Gafbacik N, Gafbacik S, Stewart K, Merricks EP, Nichols TC, Bellinger DA, Clemmons DR.

Atherosclerosis. 2017 Mar;258:40-50. doi: 10.1016/j.atherosclerosis.2017.01.030. Epub 2017 Jan 27.

PMID:
28189040
2.

Blocking αVβ3 integrin ligand occupancy inhibits the progression of albuminuria in diabetic rats.

Maile LA, Gollahon K, Wai C, Dunbar P, Busby W, Clemmons D.

J Diabetes Res. 2014;2014:421827. doi: 10.1155/2014/421827. Epub 2014 Oct 20.

3.

Blocking ligand occupancy of the αVβ3 integrin inhibits the development of nephropathy in diabetic pigs.

Maile LA, Busby WH, Gollahon KA, Flowers W, Garbacik N, Garbacik S, Stewart K, Nichols T, Bellinger D, Patel A, Dunbar P, Medlin M, Clemmons D.

Endocrinology. 2014 Dec;155(12):4665-75. doi: 10.1210/en.2014-1318. Epub 2014 Aug 29.

4.

Burn injury induces high levels of phosphorylated insulin-like growth factor binding protein-1.

Mendoza AE, Maile LA, Cairns BA, Maile R.

Int J Burns Trauma. 2013 Nov 1;3(4):180-9. eCollection 2013.

5.

The heparin-binding domains of IGFBP-2 mediate its inhibitory effect on preadipocyte differentiation and fat development in male mice.

Xi G, Solum MA, Wai C, Maile LA, Rosen CJ, Clemmons DR.

Endocrinology. 2013 Nov;154(11):4146-57. doi: 10.1210/en.2013-1236. Epub 2013 Aug 27.

6.
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8.

Hyperglycemia enhances IGF-I-stimulated Src activation via increasing Nox4-derived reactive oxygen species in a PKCζ-dependent manner in vascular smooth muscle cells.

Xi G, Shen X, Maile LA, Wai C, Gollahon K, Clemmons DR.

Diabetes. 2012 Jan;61(1):104-13. doi: 10.2337/db11-0990. Epub 2011 Dec 6.

9.

IGF-I stimulates cooperative interaction between the IGF-I receptor and CSK homologous kinase that regulates SHPS-1 phosphorylation in vascular smooth muscle cells.

Radhakrishnan Y, Shen X, Maile LA, Xi G, Clemmons DR.

Mol Endocrinol. 2011 Sep;25(9):1636-49. doi: 10.1210/me.2011-0035. Epub 2011 Jul 28.

10.

An essential role for the association of CD47 to SHPS-1 in skeletal remodeling.

Maile LA, DeMambro VE, Wai C, Lotinun S, Aday AW, Capps BE, Beamer WG, Rosen CJ, Clemmons DR.

J Bone Miner Res. 2011 Sep;26(9):2068-81. doi: 10.1002/jbmr.441. Erratum in: J Bone Miner Res. 2011 Nov;26(11):2792. Lotinun, Sutada [added].

11.

Aldosterone enhances IGF-I-mediated signaling and biological function in vascular smooth muscle cells.

Cascella T, Radhakrishnan Y, Maile LA, Busby WH Jr, Gollahon K, Colao A, Clemmons DR.

Endocrinology. 2010 Dec;151(12):5851-64. doi: 10.1210/en.2010-0350. Epub 2010 Sep 29.

12.

Glucose regulation of thrombospondin and its role in the modulation of smooth muscle cell proliferation.

Maile LA, Allen LB, Hanzaker CF, Gollahon KA, Dunbar P, Clemmons DR.

Exp Diabetes Res. 2010;2010. pii: 617052. doi: 10.1155/2010/617052. Epub 2010 Jun 20.

13.

IGF-I activation of the AKT pathway is impaired in visceral but not subcutaneous preadipocytes from obese subjects.

Cleveland-Donovan K, Maile LA, Tsiaras WG, Tchkonia T, Kirkland JL, Boney CM.

Endocrinology. 2010 Aug;151(8):3752-63. doi: 10.1210/en.2010-0043. Epub 2010 Jun 16.

14.

A monoclonal antibody against alphaVbeta3 integrin inhibits development of atherosclerotic lesions in diabetic pigs.

Maile LA, Busby WH, Nichols TC, Bellinger DA, Merricks EP, Rowland M, Veluvolu U, Clemmons DR.

Sci Transl Med. 2010 Feb 10;2(18):18ra11. doi: 10.1126/scitranslmed.3000476.

15.

Insulin-like growth factor-I-stimulated insulin receptor substrate-1 negatively regulates Src homology 2 domain-containing protein-tyrosine phosphatase substrate-1 function in vascular smooth muscle cells.

Radhakrishnan Y, Busby WH Jr, Shen X, Maile LA, Clemmons DR.

J Biol Chem. 2010 May 21;285(21):15682-95. doi: 10.1074/jbc.M109.092270. Epub 2010 Mar 5.

16.

Identification of compounds that inhibit IGF-I signaling in hyperglycemia.

Maile LA, Allen LB, Veluvolu U, Capps BE, Busby WH, Rowland M, Clemmons DR.

Exp Diabetes Res. 2009;2009:267107. doi: 10.1155/2009/267107. Epub 2010 Jan 6.

17.

Glucose-oxidized low-density lipoproteins enhance insulin-like growth factor I-stimulated smooth muscle cell proliferation by inhibiting integrin-associated protein cleavage.

Allen LB, Capps BE, Miller EC, Clemmons DR, Maile LA.

Endocrinology. 2009 Mar;150(3):1321-9. doi: 10.1210/en.2008-1090. Epub 2008 Oct 30. Erratum in: Endocrinology. 2010 Jun;151(6):2967.

18.

Integrin-associated protein association with SRC homology 2 domain containing tyrosine phosphatase substrate 1 regulates igf-I signaling in vivo.

Maile LA, Capps BE, Miller EC, Aday AW, Clemmons DR.

Diabetes. 2008 Oct;57(10):2637-43. doi: 10.2337/db08-0326. Epub 2008 Jul 15.

19.

Modulation of integrin antagonist signaling by ligand binding of the heparin-binding domain of vitronectin to the alphaVbeta3 integrin.

Maile LA, Aday AW, Busby WH, Sanghani R, Veluvolu U, Clemmons DR.

J Cell Biochem. 2008 Oct 1;105(2):437-46. doi: 10.1002/jcb.21841.

20.

Insulin-like growth factor-I stimulates Shc-dependent phosphatidylinositol 3-kinase activation via Grb2-associated p85 in vascular smooth muscle cells.

Radhakrishnan Y, Maile LA, Ling Y, Graves LM, Clemmons DR.

J Biol Chem. 2008 Jun 13;283(24):16320-31. doi: 10.1074/jbc.M801687200. Epub 2008 Apr 16.

21.

Glucose regulation of integrin-associated protein cleavage controls the response of vascular smooth muscle cells to insulin-like growth factor-I.

Maile LA, Capps BE, Miller EC, Allen LB, Veluvolu U, Aday AW, Clemmons DR.

Mol Endocrinol. 2008 May;22(5):1226-37. doi: 10.1210/me.2007-0552. Epub 2008 Feb 21.

22.

Regulation of igf-I signaling in retinal endothelial cells by hyperglycemia.

Miller EC, Capps BE, Sanghani RR, Clemmons DR, Maile LA.

Invest Ophthalmol Vis Sci. 2007 Aug;48(8):3878-87.

PMID:
17652764
23.
24.

Role of the integrin alphaVbeta3 in mediating increased smooth muscle cell responsiveness to IGF-I in response to hyperglycemic stress.

Clemmons DR, Maile LA, Ling Y, Yarber J, Busby WH.

Growth Horm IGF Res. 2007 Aug;17(4):265-70. Epub 2007 Apr 6. Review.

25.

Hyperglycemia alters the responsiveness of smooth muscle cells to insulin-like growth factor-I.

Maile LA, Capps BE, Ling Y, Xi G, Clemmons DR.

Endocrinology. 2007 May;148(5):2435-43. Epub 2007 Jan 25.

PMID:
17255202
26.

The heparin binding domain of vitronectin is the region that is required to enhance insulin-like growth factor-I signaling.

Maile LA, Busby WH, Sitko K, Capps BE, Sergent T, Badley-Clarke J, Ling Y, Clemmons DR.

Mol Endocrinol. 2006 Apr;20(4):881-92. Epub 2005 Dec 1.

PMID:
16322097
28.

Insulin-like growth factor-I signaling in smooth muscle cells is regulated by ligand binding to the 177CYDMKTTC184 sequence of the beta3-subunit of alphaVbeta3.

Maile LA, Busby WH, Sitko K, Capps BE, Sergent T, Badley-Clarke J, Clemmons DR.

Mol Endocrinol. 2006 Feb;20(2):405-13. Epub 2005 Sep 29.

PMID:
16195248
29.

Role of SHPS-1 in the regulation of insulin-like growth factor I-stimulated Shc and mitogen-activated protein kinase activation in vascular smooth muscle cells.

Ling Y, Maile LA, Lieskovska J, Badley-Clarke J, Clemmons DR.

Mol Biol Cell. 2005 Jul;16(7):3353-64. Epub 2005 May 11.

30.

Insulin-like growth factor binding protein-5 (IGFBP-5) interacts with thrombospondin-1 to induce negative regulatory effects on IGF-I actions.

Moralez AM, Maile LA, Clarke J, Busby WH Jr, Clemmons DR.

J Cell Physiol. 2005 May;203(2):328-34.

PMID:
15700281
31.
33.
34.
38.

Regulation of insulin-like growth factor I receptor dephosphorylation by SHPS-1 and the tyrosine phosphatase SHP-2.

Maile LA, Clemmons DR.

J Biol Chem. 2002 Mar 15;277(11):8955-60. Epub 2002 Jan 4.

40.

Structural analysis of the role of the beta 3 subunit of the alpha V beta 3 integrin in IGF-I signaling.

Maile LA, Badley-Clarke J, Clemmons DR.

J Cell Sci. 2001 Apr;114(Pt 7):1417-25.

41.

Endogenous IGFBP-3 is protected from inducible IGFBP-3 protease activity in normal adult serum.

Maile LA, Whellams EJ, Holly JM.

Growth Horm IGF Res. 2000 Apr;10(2):71-7.

PMID:
10931744
42.

Alterations in insulin-like growth factor binding protein-3 proteolysis and complex formation in the arthritic joint.

Whellams EJ, Maile LA, Fernihough JK, Billingham ME, Holly JM.

J Endocrinol. 2000 Jun;165(3):545-56.

PMID:
10828838
44.

Insulin-like growth factor binding protein (IGFBP) proteolysis: occurrence, identification, role and regulation.

Maile LA, Holly JM.

Growth Horm IGF Res. 1999 Apr;9(2):85-95. Review. No abstract available.

PMID:
10373341
45.

Active and inhibitory components of the insulin-like growth factor binding protein-3 protease system in adult serum, interstitial, and synovial fluid.

Maile LA, Xu S, Cwyfan-Hughes SC, Fernihough JK, Pell JM, Holly JM.

Endocrinology. 1998 Dec;139(12):4772-81.

PMID:
9832413
46.

Ovarian dysfunction in endometriosis-associated and unexplained infertility.

Cahill DJ, Wardle PG, Maile LA, Harlow CR, Hull MG.

J Assist Reprod Genet. 1997 Nov;14(10):554-7.

47.

Antibiotic treatment based on seminal cultures from asymptomatic male partners in in-vitro fertilization is unnecessary and may be detrimental.

Liversedge NH, Jenkins JM, Keay SD, McLaughlin EA, Al-Sufyan H, Maile LA, Joels LA, Hull MG.

Hum Reprod. 1996 Jun;11(6):1227-31.

PMID:
8671429
48.

Reduced preovulatory granulosa cell steroidogenesis in women with endometriosis.

Harlow CR, Cahill DJ, Maile LA, Talbot WM, Mears J, Wardle PG, Hull MG.

J Clin Endocrinol Metab. 1996 Jan;81(1):426-9.

PMID:
8550788
49.

Pituitary-ovarian dysfunction as a cause for endometriosis-associated and unexplained infertility.

Cahill DJ, Wardle PG, Maile LA, Harlow CR, Hull MG.

Hum Reprod. 1995 Dec;10(12):3142-46.

PMID:
8822432
50.

Time-dependent effects of transforming growth factor alpha on aromatase activity in human granulosa cells.

Harlow CR, Cahill DJ, Maile LA, Wardle PG, Hull MG.

Hum Reprod. 1995 Oct;10(10):2554-9.

PMID:
8567769

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