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Items: 14


Intrinsically active MEK variants are differentially regulated by proteinases and phosphatases.

Ordan M, Pallara C, Maik-Rachline G, Hanoch T, Gervasio FL, Glaser F, Fernandez-Recio J, Seger R.

Sci Rep. 2018 Aug 7;8(1):11830. doi: 10.1038/s41598-018-30202-5.


The nuclear translocation of the kinases p38 and JNK promotes inflammation-induced cancer.

Maik-Rachline G, Zehorai E, Hanoch T, Blenis J, Seger R.

Sci Signal. 2018 Apr 10;11(525). pii: eaao3428. doi: 10.1126/scisignal.aao3428.


Combined inhibition of MEK and nuclear ERK translocation has synergistic antitumor activity in melanoma cells.

Arafeh R, Flores K, Keren-Paz A, Maik-Rachline G, Gutkind N, Rosenberg S, Seger R, Samuels Y.

Sci Rep. 2017 Nov 27;7(1):16345. doi: 10.1038/s41598-017-16558-0.


Activation of Signaling Cascades by Weak Extremely Low Frequency Electromagnetic Fields.

Kapri-Pardes E, Hanoch T, Maik-Rachline G, Murbach M, Bounds PL, Kuster N, Seger R.

Cell Physiol Biochem. 2017;43(4):1533-1546. doi: 10.1159/000481977. Epub 2017 Oct 16.


The ERK cascade inhibitors: Towards overcoming resistance.

Maik-Rachline G, Seger R.

Drug Resist Updat. 2016 Mar;25:1-12. doi: 10.1016/j.drup.2015.12.001. Epub 2016 Jan 2. Review.


G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination.

Yang HJ, Vainshtein A, Maik-Rachline G, Peles E.

Nat Commun. 2016 Mar 10;7:10884. doi: 10.1038/ncomms10884.


The nuclear translocation of ERK1/2 as an anticancer target.

Plotnikov A, Flores K, Maik-Rachline G, Zehorai E, Kapri-Pardes E, Berti DA, Hanoch T, Besser MJ, Seger R.

Nat Commun. 2015 Mar 30;6:6685. doi: 10.1038/ncomms7685.


Genetic deletion of Cadm4 results in myelin abnormalities resembling Charcot-Marie-Tooth neuropathy.

Golan N, Kartvelishvily E, Spiegel I, Salomon D, Sabanay H, Rechav K, Vainshtein A, Frechter S, Maik-Rachline G, Eshed-Eisenbach Y, Momoi T, Peles E.

J Neurosci. 2013 Jul 3;33(27):10950-61. doi: 10.1523/JNEUROSCI.0571-13.2013.


Induction of cell-cell fusion by ectromelia virus is not inhibited by its fusion inhibitory complex.

Erez N, Paran N, Maik-Rachline G, Politi B, Israely T, Schnider P, Fuchs P, Melamed S, Lustig S.

Virol J. 2009 Sep 29;6:151. doi: 10.1186/1743-422X-6-151.


Effective post-exposure protection against lethal orthopoxviruses infection by vaccinia immune globulin involves induction of adaptive immune response.

Lustig S, Maik-Rachline G, Paran N, Melamed S, Israely T, Erez N, Orr N, Reuveny S, Ordentlich A, Laub O, Shafferman A, Velan B.

Vaccine. 2009 Mar 10;27(11):1691-9. doi: 10.1016/j.vaccine.2009.01.038. Epub 2009 Feb 3.


Variable phosphorylation states of pigment-epithelium-derived factor differentially regulate its function.

Maik-Rachline G, Seger R.

Blood. 2006 Apr 1;107(7):2745-52. Epub 2005 Dec 1.


Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity.

Kochupurakkal BS, Harari D, Di-Segni A, Maik-Rachline G, Lyass L, Gur G, Kerber G, Citri A, Lavi S, Eilam R, Chalifa-Caspi V, Eshhar Z, Pikarsky E, Pinkas-Kramarski R, Bacus SS, Yarden Y.

J Biol Chem. 2005 Mar 4;280(9):8503-12. Epub 2004 Dec 17.


Extracellular phosphorylation converts pigment epithelium-derived factor from a neurotrophic to an antiangiogenic factor.

Maik-Rachline G, Shaltiel S, Seger R.

Blood. 2005 Jan 15;105(2):670-8. Epub 2004 Sep 16.


Truncated vitronectins: binding to immobilized fibrin and to fibrin clots, and their subsequent interaction with cells.

Schvartz I, Seger D, Maik-Rachline G, Kreizman T, Shaltiel S.

Biochem Biophys Res Commun. 2002 Jan 18;290(2):682-9.


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