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Polymorphism of FCGR3A gene in chronic beryllium disease.

Liu B, Maier LA, Hamzeh N, MacPhail K, Mroz MM, Liu H, Li L.

Genes Immun. 2018 Sep 24. doi: 10.1038/s41435-018-0046-8. [Epub ahead of print]


Activation of protein phosphatase 1 by a selective phosphatase disrupting peptide reduces sarcoplasmic reticulum Ca2+ leak in human heart failure.

Fischer TH, Eiringhaus J, Dybkova N, Saadatmand A, Pabel S, Weber S, Wang Y, Köhn M, Tirilomis T, Ljubojevic S, Renner A, Gummert J, Maier LS, Hasenfuß G, El-Armouche A, Sossalla S.

Eur J Heart Fail. 2018 Sep 7. doi: 10.1002/ejhf.1297. [Epub ahead of print]


One-Year Outcomes after PCI Strategies in Cardiogenic Shock.

Thiele H, Akin I, Sandri M, de Waha-Thiele S, Meyer-Saraei R, Fuernau G, Eitel I, Nordbeck P, Geisler T, Landmesser U, Skurk C, Fach A, Jobs A, Lapp H, Piek JJ, Noc M, Goslar T, Felix SB, Maier LS, Stepinska J, Oldroyd K, Serpytis P, Montalescot G, Barthelemy O, Huber K, Windecker S, Hunziker L, Savonitto S, Torremante P, Vrints C, Schneider S, Zeymer U, Desch S; CULPRIT-SHOCK Investigators.

N Engl J Med. 2018 Aug 25. doi: 10.1056/NEJMoa1808788. [Epub ahead of print]


DNA Methylation Changes in Lung Immune Cells are Associated with Granulomatous Lung Disease.

Yang IV, Konigsberg I, MacPhail K, Li L, Davidson EJ, Mroz PM, Hamzeh N, Gillespie M, Silveira LJ, Fingerlin TE, Maier LA.

Am J Respir Cell Mol Biol. 2018 Aug 24. doi: 10.1165/rcmb.2018-0177OC. [Epub ahead of print]


Empagliflozin reduces Ca/calmodulin-dependent kinase II activity in isolated ventricular cardiomyocytes.

Mustroph J, Wagemann O, Lücht CM, Trum M, Hammer KP, Sag CM, Lebek S, Tarnowski D, Reinders J, Perbellini F, Terracciano C, Schmid C, Schopka S, Hilker M, Zausig Y, Pabel S, Sossalla ST, Schweda F, Maier LS, Wagner S.

ESC Heart Fail. 2018 Aug;5(4):642-648. doi: 10.1002/ehf2.12336.


Unraveling mitotic protein networks by 3D multiplexed epitope drug screening.

Maier LJ, Kallenberger SM, Jechow K, Waschow M, Eils R, Conrad C.

Mol Syst Biol. 2018 Aug 13;14(8):e8238. doi: 10.15252/msb.20188238.


The detrimental potential of arrhythmia-induced cardiomyopathy.

Eiringhaus J, Hamer OW, Hollemann D, Brochhausen C, Vollmann D, Maier LS, Sossalla S.

ESC Heart Fail. 2018 Aug 6. doi: 10.1002/ehf2.12343. [Epub ahead of print]


The German CPU registry: Comparison of smokers and nonsmokers.

Bock D, Senges J, Pohlmann C, Hochadel M, Münzel T, Giannitsis E, Schmitt C, Heusch G, Voigtländer T, Mudra H, Schumacher B, Darius H, Maier LS, Hailer B, Haude M, Gohlke H, Hink U.

Herz. 2018 Jul 27. doi: 10.1007/s00059-018-4733-z. [Epub ahead of print]


Clinical care for patients with recurrent myocardial ischemia in Germany-the VOICES trial.

Berliner D, Maier LS, Wollenberg U, Limberg R, Schmitto JD, Westermann D, Bauersachs J.

J Thorac Dis. 2018 Jun;10(Suppl 15):S1777-S1784. doi: 10.21037/jtd.2017.10.123.


Is it time to scrap Scadding and adopt computed tomography for initial evaluation of sarcoidosis?

Levy A, Hamzeh N, Maier LA.

F1000Res. 2018 May 16;7. pii: F1000 Faculty Rev-600. doi: 10.12688/f1000research.11068.1. eCollection 2018. Review.


Postoperative complications after elective coronary artery bypass grafting surgery in patients with sleep-disordered breathing.

Tafelmeier M, Weizenegger T, Ripfel S, Fauser M, Floerchinger B, Camboni D, Zausig Y, Wittmann S, Drzymalski MA, Zeman F, Schmid C, Maier LS, Wagner S, Arzt M.

Clin Res Cardiol. 2018 Jun 12. doi: 10.1007/s00392-018-1289-0. [Epub ahead of print]


Differential regulation of sodium channels as a novel proarrhythmic mechanism in the human failing heart.

Dybkova N, Ahmad S, Pabel S, Tirilomis P, Hartmann N, Fischer TH, Bengel P, Tirilomis T, Ljubojevic S, Renner A, Gummert J, Ellenberger D, Wagner S, Frey N, Maier LS, Streckfuss-Boemeke K, Hasenfuss G, Sossalla S.

Cardiovasc Res. 2018 Jun 20. doi: 10.1093/cvr/cvy152. [Epub ahead of print]


Pharmacological cognitive enhancement among non-ADHD individuals-A cross-sectional study in 15 countries.

Maier LJ, Ferris JA, Winstock AR.

Int J Drug Policy. 2018 Aug;58:104-112. doi: 10.1016/j.drugpo.2018.05.009. Epub 2018 Jun 11.


SCN10A-Dependent Late INa Current: Never Too Late for Cardiac Conduction?

Maier LS, Sossalla S, Schulze-Bahr E.

Circ Genom Precis Med. 2018 May;11(5):e002167. doi: 10.1161/CIRCGEN.118.002167. No abstract available.


Are ecstasy induced serotonergic alterations overestimated for the majority of users?

Szigeti B, Winstock AR, Erritzoe D, Maier LJ.

J Psychopharmacol. 2018 Jul;32(7):741-748. doi: 10.1177/0269881118767646. Epub 2018 May 7.


The impact of drug policy liberalisation on willingness to seek help for problem drug use: A comparison of 20 countries.

Benfer I, Zahnow R, Barratt MJ, Maier L, Winstock A, Ferris J.

Int J Drug Policy. 2018 Jun;56:162-175. doi: 10.1016/j.drugpo.2018.03.032. Epub 2018 May 3.


Drug-related police encounters across the globe: How do they compare?

Hughes CE, Barratt MJ, Ferris JA, Maier LJ, Winstock AR.

Int J Drug Policy. 2018 Jun;56:197-207. doi: 10.1016/j.drugpo.2018.03.005. Epub 2018 Apr 24.


Insights into RNA-processing pathways and associated RNA-degrading enzymes in Archaea.

Clouet-d'Orval B, Batista M, Bouvier M, Quentin Y, Fichant G, Marchfelder A, Maier LK.

FEMS Microbiol Rev. 2018 Sep 1;42(5):579-613. doi: 10.1093/femsre/fuy016.


Introduction to the 60th Annual Thomas L. Petty Aspen Lung Conference. Environment and Global Lung Health: Exposure, Susceptibility, and Intervention.

Maier LA, Brody AR, Schwartz DA.

Ann Am Thorac Soc. 2018 Apr;15(Supplement_2):S61-S63. doi: 10.1513/AnnalsATS.201707-576MG. No abstract available.


A Pilot Study Assessing the Ability of 5-Aminosalicylic Acid to Modulate the Immune Response in Chronic Beryllium Disease.

Day BJ, Huang J, Barkes BQ, Gillespie M, Li L, Maier LA.

Ann Am Thorac Soc. 2018 Apr;15(Supplement_2):S133. doi: 10.1513/AnnalsATS.201709-720MG.


The nuts and bolts of the Haloferax CRISPR-Cas system I-B.

Maier LK, Stachler AE, Brendel J, Stoll B, Fischer S, Haas KA, Schwarz TS, Alkhnbashi OS, Sharma K, Urlaub H, Backofen R, Gophna U, Marchfelder A.

RNA Biol. 2018 May 21:1-12. doi: 10.1080/15476286.2018.1460994. [Epub ahead of print]


Injecting drug use: Gendered risk.

Zahnow R, Winstock AR, Maier LJ, Levy J, Ferris J.

Int J Drug Policy. 2018 Jun;56:81-91. doi: 10.1016/j.drugpo.2018.03.018. Epub 2018 Mar 31.


The novel CaMKII inhibitor GS-680 reduces diastolic SR Ca leak and prevents CaMKII-dependent pro-arrhythmic activity.

Lebek S, Plößl A, Baier M, Mustroph J, Tarnowski D, Lücht CM, Schopka S, Flörchinger B, Schmid C, Zausig Y, Pagratis N, Marchand B, Koltun DO, Hung WK, Ahmadyar S, Belardinelli L, Maier LS, Wagner S.

J Mol Cell Cardiol. 2018 May;118:159-168. doi: 10.1016/j.yjmcc.2018.03.020. Epub 2018 Mar 31.


Do people with intersecting identities report more high-risk alcohol use and lifetime substance use?

Demant D, Oviedo-Trespalacios O, Carroll JA, Ferris JA, Maier L, Barratt MJ, Winstock AR.

Int J Public Health. 2018 Jun;63(5):621-630. doi: 10.1007/s00038-018-1095-5. Epub 2018 Mar 31.


Clinical and laboratory factors contributing to uninterpretable beryllium lymphocyte proliferation tests (BeLPT).

Smith DE, Golden AP, Stange AW, Barker E, Mroz M, Barón AE, Ghosh D, Maier L, Cragle D, Newman LS.

Am J Ind Med. 2018 Jul;61(7):592-604. doi: 10.1002/ajim.22842. Epub 2018 Mar 24.


Extensive impact of non-antibiotic drugs on human gut bacteria.

Maier L, Pruteanu M, Kuhn M, Zeller G, Telzerow A, Anderson EE, Brochado AR, Fernandez KC, Dose H, Mori H, Patil KR, Bork P, Typas A.

Nature. 2018 Mar 29;555(7698):623-628. doi: 10.1038/nature25979. Epub 2018 Mar 19.


Cardiac unloading by LVAD support differentially influences components of the cGMP-PKG signaling pathway in ischemic and dilated cardiomyopathy.

Persoon S, Paulus M, Hirt S, Jungbauer C, Dietl A, Luchner A, Schmid C, Maier LS, Birner C.

Heart Vessels. 2018 Aug;33(8):948-957. doi: 10.1007/s00380-018-1149-x. Epub 2018 Mar 15.


Guideline-adherence regarding critical time intervals in the German Chest Pain Unit registry.

Vafaie M, Hochadel M, Münzel T, Hailer B, Schumacher B, Heusch G, Voigtländer T, Mudra H, Haude M, Barth S, Schmitt C, Darius H, Maier LS, Katus HA, Senges J, Giannitsis E.

Eur Heart J Acute Cardiovasc Care. 2018 Mar 1:2048872618762639. doi: 10.1177/2048872618762639. [Epub ahead of print]


CaRMeN: a tool for analysing and deriving kinetics in the real world.

Gossler H, Maier L, Angeli S, Tischer S, Deutschmann O.

Phys Chem Chem Phys. 2018 Apr 25;20(16):10857-10876. doi: 10.1039/c7cp07777g.


Sleep-disordered breathing is associated with disturbed cardiac repolarization in patients with a coronary artery bypass graft surgery.

Schmidleitner C, Arzt M, Tafelmeier M, Ripfel S, Fauser M, Weizenegger T, Flörchinger B, Camboni D, Wittmann S, Zeman F, Schmid C, Maier LS, Wagner S, Fisser C.

Sleep Med. 2018 Feb;42:13-20. doi: 10.1016/j.sleep.2017.12.007. Epub 2018 Jan 8.


Effect of inhaled corticosteroids on lung function in chronic beryllium disease.

Mroz MM, Ferguson JH, Faino AV, Mayer A, Strand M, Maier LA.

Respir Med. 2018 May;138S:S14-S19. doi: 10.1016/j.rmed.2018.01.009. Epub 2018 Feb 5.


Impact of treatment delay on mortality in ST-segment elevation myocardial infarction (STEMI) patients presenting with and without haemodynamic instability: results from the German prospective, multicentre FITT-STEMI trial.

Scholz KH, Maier SKG, Maier LS, Lengenfelder B, Jacobshagen C, Jung J, Fleischmann C, Werner GS, Olbrich HG, Ott R, Mudra H, Seidl K, Schulze PC, Weiss C, Haimerl J, Friede T, Meyer T.

Eur Heart J. 2018 Apr 1;39(13):1065-1074. doi: 10.1093/eurheartj/ehy004.


A RAndomized Trial to compare the acute reconnection after pulmonary vein ISolation with Laser-BalloON versus radiofrequency Ablation: RATISBONA trial.

Ücer E, Janeczko Y, Seegers J, Fredersdorf S, Friemel S, Poschenrieder F, Maier LS, Jungbauer CG.

J Cardiovasc Electrophysiol. 2018 May;29(5):733-739. doi: 10.1111/jce.13465. Epub 2018 Mar 8.


Long-term outcomes and predictors of recurrence after pulmonary vein isolation with multielectrode ablation catheter in patients with atrial fibrillation.

Fredersdorf S, Fenzl C, Jungbauer C, Weber S, von Bary C, Dietl A, Seegers J, Maier LS, Ücer E.

J Cardiovasc Med (Hagerstown). 2018 Apr;19(4):148-154. doi: 10.2459/JCM.0000000000000631.


Invasive treatment of NSTEMI patients in German Chest Pain Units - Evidence for a treatment paradox.

Schmidt FP, Schmitt C, Hochadel M, Giannitsis E, Darius H, Maier LS, Schmitt C, Heusch G, Voigtländer T, Mudra H, Gori T, Senges J, Münzel T; German Chest Pain Unit Registry.

Int J Cardiol. 2018 Mar 15;255:15-19. doi: 10.1016/j.ijcard.2017.11.018.


SR Ca2+-leak and disordered excitation-contraction coupling as the basis for arrhythmogenic and negative inotropic effects of acute ethanol exposure.

Mustroph J, Wagemann O, Lebek S, Tarnowski D, Ackermann J, Drzymalski M, Pabel S, Schmid C, Wagner S, Sossalla S, Maier LS, Neef S.

J Mol Cell Cardiol. 2018 Mar;116:81-90. doi: 10.1016/j.yjmcc.2018.02.002. Epub 2018 Feb 3.


Adaptive servo-ventilation and sleep quality in treatment emergent central sleep apnea and central sleep apnea in patients with heart disease and preserved ejection fraction.

Heider K, Arzt M, Lerzer C, Kolb L, Pfeifer M, Maier LS, Gfüllner F, Malfertheiner MV.

Clin Res Cardiol. 2018 May;107(5):421-429. doi: 10.1007/s00392-018-1203-9. Epub 2018 Jan 25.


Nocturnal hypoxemic burden is associated with epicardial fat volume in patients with acute myocardial infarction.

Linz D, Colling S, Nußstein W, Debl K, Hohl M, Fellner C, Böhm M, Maier LS, Hamer OW, Buchner S, Arzt M.

Sleep Breath. 2018 Sep;22(3):703-711. doi: 10.1007/s11325-017-1616-0. Epub 2018 Jan 11.


Efficacy of Ranolazine in Patients With Symptomatic Hypertrophic Cardiomyopathy: The RESTYLE-HCM Randomized, Double-Blind, Placebo-Controlled Study.

Olivotto I, Camici PG, Merlini PA, Rapezzi C, Patten M, Climent V, Sinagra G, Tomberli B, Marin F, Ehlermann P, Maier LS, Fornaro A, Jacobshagen C, Ganau A, Moretti L, Hernandez Madrid A, Coppini R, Reggiardo G, Poggesi C, Fattirolli F, Belardinelli L, Gensini G, Mugelli A.

Circ Heart Fail. 2018 Jan;11(1):e004124. doi: 10.1161/CIRCHEARTFAILURE.117.004124.


3D vena contracta area after MitraClip© procedure: precise quantification of residual mitral regurgitation and identification of prognostic information.

Dietl A, Prieschenk C, Eckert F, Birner C, Luchner A, Maier LS, Buchner S.

Cardiovasc Ultrasound. 2018 Jan 9;16(1):1. doi: 10.1186/s12947-017-0120-9.


Improvement of cardiomyocyte function by a novel pyrimidine-based CaMKII-inhibitor.

Neef S, Steffens A, Pellicena P, Mustroph J, Lebek S, Ort KR, Schulman H, Maier LS.

J Mol Cell Cardiol. 2018 Feb;115:73-81. doi: 10.1016/j.yjmcc.2017.12.015. Epub 2017 Dec 30.


A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway.

Lehmann LH, Jebessa ZH, Kreusser MM, Horsch A, He T, Kronlage M, Dewenter M, Sramek V, Oehl U, Krebs-Haupenthal J, von der Lieth AH, Schmidt A, Sun Q, Ritterhoff J, Finke D, Völkers M, Jungmann A, Sauer SW, Thiel C, Nickel A, Kohlhaas M, Schäfer M, Sticht C, Maack C, Gretz N, Wagner M, El-Armouche A, Maier LS, Londoño JEC, Meder B, Freichel M, Gröne HJ, Most P, Müller OJ, Herzig S, Furlong EEM, Katus HA, Backs J.

Nat Med. 2018 Jan;24(1):62-72. doi: 10.1038/nm.4452. Epub 2017 Dec 11.


Systematically investigating the impact of medication on the gut microbiome.

Maier L, Typas A.

Curr Opin Microbiol. 2017 Oct;39:128-135. doi: 10.1016/j.mib.2017.11.001. Review.


Clinical tool for disease phenotyping in granulomatous lung disease.

Silveira LJ, Strand M, Van Dyke MV, Mroz MM, Faino AV, Dabelea DM, Maier LA, Fingerlin TE.

PLoS One. 2017 Nov 16;12(11):e0188119. doi: 10.1371/journal.pone.0188119. eCollection 2017.


Salt-responsive gut commensal modulates TH17 axis and disease.

Wilck N, Matus MG, Kearney SM, Olesen SW, Forslund K, Bartolomaeus H, Haase S, Mähler A, Balogh A, Markó L, Vvedenskaya O, Kleiner FH, Tsvetkov D, Klug L, Costea PI, Sunagawa S, Maier L, Rakova N, Schatz V, Neubert P, Frätzer C, Krannich A, Gollasch M, Grohme DA, Côrte-Real BF, Gerlach RG, Basic M, Typas A, Wu C, Titze JM, Jantsch J, Boschmann M, Dechend R, Kleinewietfeld M, Kempa S, Bork P, Linker RA, Alm EJ, Müller DN.

Nature. 2017 Nov 30;551(7682):585-589. doi: 10.1038/nature24628. Epub 2017 Nov 15.


Atropine augments cardiac contractility by inhibiting cAMP-specific phosphodiesterase type 4.

Perera RK, Fischer TH, Wagner M, Dewenter M, Vettel C, Bork NI, Maier LS, Conti M, Wess J, El-Armouche A, Hasenfuß G, Nikolaev VO.

Sci Rep. 2017 Nov 9;7(1):15222. doi: 10.1038/s41598-017-15632-x.


PCI Strategies in Patients with Acute Myocardial Infarction and Cardiogenic Shock.

Thiele H, Akin I, Sandri M, Fuernau G, de Waha S, Meyer-Saraei R, Nordbeck P, Geisler T, Landmesser U, Skurk C, Fach A, Lapp H, Piek JJ, Noc M, Goslar T, Felix SB, Maier LS, Stepinska J, Oldroyd K, Serpytis P, Montalescot G, Barthelemy O, Huber K, Windecker S, Savonitto S, Torremante P, Vrints C, Schneider S, Desch S, Zeymer U; CULPRIT-SHOCK Investigators.

N Engl J Med. 2017 Dec 21;377(25):2419-2432. doi: 10.1056/NEJMoa1710261. Epub 2017 Oct 30.


5-Aminosalicylic Acid Modulates the Immune Response in Chronic Beryllium Disease Subjects.

Day BJ, Huang J, Barkes BQ, Gillespie M, Li L, Maier LA.

Lung. 2018 Feb;196(1):103-114. doi: 10.1007/s00408-017-0062-x. Epub 2017 Oct 27.


Clinical Course of Sarcoidosis in World Trade Center-Exposed Firefighters.

Hena KM, Yip J, Jaber N, Goldfarb D, Fullam K, Cleven K, Moir W, Zeig-Owens R, Webber MP, Spevack DM, Judson MA, Maier L, Krumerman A, Aizer A, Spivack SD, Berman J, Aldrich TK, Prezant DJ; FDNY Sarcoidosis Clinical Research Group*.

Chest. 2018 Jan;153(1):114-123. doi: 10.1016/j.chest.2017.10.014. Epub 2017 Oct 21.


Application of "Omics" and Systems Biology to Sarcoidosis Research.

Crouser ED, Fingerlin TE, Yang IV, Maier LA, Nana-Sinkam P, Collman RG, Kaminski N.

Ann Am Thorac Soc. 2017 Dec;14(Supplement_6):S445-S451. doi: 10.1513/AnnalsATS.201707-567OT. Review.


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