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Adjunctive dexamethasone for the treatment of HIV-infected adults with tuberculous meningitis (ACT HIV): Study protocol for a randomised controlled trial.

Donovan J, Phu NH, Mai NTH, Dung LT, Imran D, Burhan E, Ngoc LHB, Bang ND, Giang DC, Ha DTM, Day J, Thao LTP, Thuong NT, Vien NN, Geskus RB, Wolbers M, Hamers RL, van Crevel R, Nursaya M, Maharani K, Hien TT, Baird K, Lan NH, Kestelyn E, Chau NVV, Thwaites GE.

Version 2. Wellcome Open Res. 2018 Jun 20 [revised 2018 Jan 1];3:31. doi: 10.12688/wellcomeopenres.14006.2. eCollection 2018.


Pre-treatment cerebrospinal fluid bacterial load correlates with inflammatory response and predicts neurological events during tuberculous meningitis treatment.

Thuong NTT, Vinh DN, Hai HT, Thu DDA, Nhat LTH, Heemskerk D, Bang ND, Caws M, Mai NTH, Thwaites GE.

J Infect Dis. 2018 Oct 9. doi: 10.1093/infdis/jiy588. [Epub ahead of print]


Improving the microbiological diagnosis of tuberculous meningitis: A prospective, international, multicentre comparison of conventional and modified Ziehl-Neelsen stain, GeneXpert, and culture of cerebrospinal fluid.

Heemskerk AD, Donovan J, Thu DDA, Marais S, Chaidir L, Dung VTM, Centner CM, Ha VTN, Annisa J, Dian S, Bovijn L, Mai NTH, Phu NH, Chau NVV, Ganiem AR, Van CT, Geskus RB, Thuong NTT, Ruslami R, Meintjes G, van Crevel R, Wilkinson RJ, Thwaites GE.

J Infect. 2018 Sep 12. pii: S0163-4453(18)30276-7. doi: 10.1016/j.jinf.2018.09.003. [Epub ahead of print]


OXA1L mutations cause mitochondrial encephalopathy and a combined oxidative phosphorylation defect.

Thompson K, Mai N, Oláhová M, Scialó F, Formosa LE, Stroud DA, Garrett M, Lax NZ, Robertson FM, Jou C, Nascimento A, Ortez C, Jimenez-Mallebrera C, Hardy SA, He L, Brown GK, Marttinen P, McFarland R, Sanz A, Battersby BJ, Bonnen PE, Ryan MT, Chrzanowska-Lightowlers ZM, Lightowlers RN, Taylor RW.

EMBO Mol Med. 2018 Sep 10. pii: e9060. doi: 10.15252/emmm.201809060. [Epub ahead of print]


Kynurenine pathway changes in late-life depression with memory deficit.

Wu Y, Mai N, Zhong X, Wen Y, Zhou Y, Li H, Shang D, Hu L, Chen X, Chen B, Zhang M, Ning Y.

Psychiatry Res. 2018 Aug 13;269:45-49. doi: 10.1016/j.psychres.2018.08.041. [Epub ahead of print]


A reliable global cognitive decline and cortisol as an associated risk factor for patients with late-life depression in the short term: A 1-year prospective study.

Zhong X, Ning Y, Gu Y, Wu Z, Ouyang C, Liang W, Chen B, Peng Q, Mai N, Wu Y, Chen X, Huang X, Pan S.

J Affect Disord. 2018 Nov;240:214-219. doi: 10.1016/j.jad.2018.07.052. Epub 2018 Jul 19.


Investigation into the environmental fate of the combined Insensitive High Explosive constituents 2,4-dinitroanisole (DNAN), 1-nitroguanidine (NQ) and nitrotriazolone (NTO) in soil.

Temple T, Ladyman M, Mai N, Galante E, Ricamora M, Shirazi R, Coulon F.

Sci Total Environ. 2018 Jun 1;625:1264-1271. doi: 10.1016/j.scitotenv.2017.12.264. Epub 2018 Jan 12.


A Pilot Study to Assess Safety and Feasibility of Intrathecal Immunoglobulin for the Treatment of Adults with Tetanus.

Loan HT, Yen LM, Kestelyn E, Hao NV, Mai NTH, Thuy DB, Duong HTH, Dung NTP, Phu NH, Lieu PT, Thanh TT, Geskus R, van Doorn HR, Tan LV, Wyncoll D, Day NPJ, Hien TT, Thwaites GE, Chau NVV, Thwaites CL.

Am J Trop Med Hyg. 2018 Aug;99(2):323-326. doi: 10.4269/ajtmh.18-0153. Epub 2018 Jun 14.


Population Pharmacokinetics and Cerebrospinal Fluid Penetration of Fluconazole in Adults with Cryptococcal Meningitis.

Stott KE, Beardsley J, Kolamunnage-Dona R, Castelazo AS, Kibengo FM, Mai NTH, Day J, Hope W.

Antimicrob Agents Chemother. 2018 Aug 27;62(9). pii: e00885-18. doi: 10.1128/AAC.00885-18. Print 2018 Sep.


Three novel mutations in the ATP7B gene of unrelated Vietnamese patients with Wilson disease.

Huong NTM, Lien NTK, Ngoc ND, Mai NTP, Hoa NPA, Hai LT, Van Chi P, Van TT, Van Khanh T, Hoang NH.

BMC Med Genet. 2018 Jun 18;19(1):104. doi: 10.1186/s12881-018-0619-4.


Population Pharmacokinetic Model and Meta-analysis of Outcomes of Amphotericin B Deoxycholate Use in Adults with Cryptococcal Meningitis.

Stott KE, Beardsley J, Whalley S, Kibengo FM, Mai NTH, Kolamunnage-Dona R, Hope W, Day J.

Antimicrob Agents Chemother. 2018 Jun 26;62(7). pii: e02526-17. doi: 10.1128/AAC.02526-17. Print 2018 Jul.


Kynurenine pathway changes in late-life depression.

Wu Y, Zhong X, Mai N, Wen Y, Shang D, Hu L, Chen B, Zhang M, Ning Y.

J Affect Disord. 2018 Aug 1;235:76-81. doi: 10.1016/j.jad.2018.04.007. Epub 2018 Apr 3.


Continuous versus intermittent endotracheal cuff pressure control for the prevention of ventilator-associated respiratory infections in Vietnam: study protocol for a randomised controlled trial.

Dat VQ, Geskus RB, Wolbers M, Loan HT, Yen LM, Binh NT, Chien LT, Mai NTH, Phu NH, Lan NPH, Hao NV, Long HB, Thuy TP, Kinh NV, Trung NV, Phu VD, Cap NT, Trinh DT, Campbell J, Kestelyn E, Wertheim HFL, Wyncoll D, Thwaites GE, van Doorn HR, Thwaites CL, Nadjm B.

Trials. 2018 Apr 4;19(1):217. doi: 10.1186/s13063-018-2587-6.


Cognitive Impairment and Structural Abnormalities in Late Life Depression with Olfactory Identification Impairment: an Alzheimer's Disease-Like Pattern.

Chen B, Zhong X, Mai N, Peng Q, Wu Z, Ouyang C, Zhang W, Liang W, Wu Y, Liu S, Chen L, Ning Y.

Int J Neuropsychopharmacol. 2018 Jul 1;21(7):640-648. doi: 10.1093/ijnp/pyy016.


A randomised double blind placebo controlled phase 2 trial of adjunctive aspirin for tuberculous meningitis in HIV-uninfected adults.

Mai NT, Dobbs N, Phu NH, Colas RA, Thao LT, Thuong NT, Nghia HD, Hanh NH, Hang NT, Heemskerk AD, Day JN, Ly L, Thu DD, Merson L, Kestelyn E, Wolbers M, Geskus R, Summers D, Chau NV, Dalli J, Thwaites GE.

Elife. 2018 Feb 27;7. pii: e33478. doi: 10.7554/eLife.33478.


Comparative Study of Hydrogel-Based Recyclable Photocatalysts.

Mai NXD, Park D, Yoon J, Hur J.

J Nanosci Nanotechnol. 2018 Feb 1;18(2):1361-1364. doi: 10.1166/jnn.2018.14929.


Aspergillus niger whole-cell catalyzed synthesis of caffeic acid phenethyl ester in ionic liquids.

Rajapriya G, Morya VK, Mai NL, Koo YM.

Enzyme Microb Technol. 2018 Apr;111:67-73. doi: 10.1016/j.enzmictec.2017.10.005. Epub 2017 Oct 16.


Dengue-Associated Posterior Reversible Encephalopathy Syndrome, Vietnam.

Mai NTH, Phu NH, Nghia HDT, Phuong TM, Duc DT, Chau NVV, Wills B, Lim CCT, Thwaites G, Simmons CP, Yacoub S.

Emerg Infect Dis. 2018 Feb;24(2):402-404. doi: 10.3201/eid2402.171634.


A Qualitative Study With Women Living With HIV on Perceived Gender Norms and Experiences of Intimate Partner Violence in Northern Vietnam.

Hershow RB, Bhadra M, Mai NVT, Sripaipan T, Ha TV, Go VF.

J Interpers Violence. 2017 Aug 1:886260517724834. doi: 10.1177/0886260517724834. [Epub ahead of print]


Ventilator-associated respiratory infection in a resource-restricted setting: impact and etiology.

Phu VD, Nadjm B, Duy NHA, Co DX, Mai NTH, Trinh DT, Campbell J, Khiem DP, Quang TN, Loan HT, Binh HS, Dinh QD, Thuy DB, Lan HNP, Ha NH, Bonell A, Larsson M, Hoan HM, Tuan ĐQ, Hanberger H, Minh HNV, Yen LM, Van Hao N, Binh NG, Chau NVV, Van Kinh N, Thwaites GE, Wertheim HF, van Doorn HR, Thwaites CL.

J Intensive Care. 2017 Dec 19;5:69. doi: 10.1186/s40560-017-0266-4. eCollection 2017.


PD-L1 Immunohistochemistry Highlights Bone Marrow Involvement by Classic Hodgkin Lymphoma in Staging Biopsies: Implications for Diagnosis and Tumor Microenvironment Alterations.

Xing W, Mai N, Dresser K, Chen BJ.

Appl Immunohistochem Mol Morphol. 2017 Dec 21. doi: 10.1097/PAI.0000000000000628. [Epub ahead of print]


Optimizing Mechanical Ventilation in the Neonatal ICU.

Hulse JL, Mai NH.

Respir Care. 2017 Dec;62(12):1615-1616. doi: 10.4187/respcare.05899. No abstract available.


Prognostic Models for 9-Month Mortality in Tuberculous Meningitis.

Thao LTP, Heemskerk AD, Geskus RB, Mai NTH, Ha DTM, Chau TTH, Phu NH, Chau NVV, Caws M, Lan NH, Thu DDA, Thuong NTT, Day J, Farrar JJ, Torok ME, Bang ND, Thwaites GE, Wolbers M.

Clin Infect Dis. 2018 Feb 1;66(4):523-532. doi: 10.1093/cid/cix849.


Negative bias in expression-related mismatch negativity(MMN) in remitted late-life depression: An event-related potential study.

Wu Z, Zhong X, Peng Q, Chen B, Mai N, Ning Y.

J Psychiatr Res. 2017 Dec;95:224-230. doi: 10.1016/j.jpsychires.2017.08.019. Epub 2017 Aug 31.


Tuberculous meningitis.

Wilkinson RJ, Rohlwink U, Misra UK, van Crevel R, Mai NTH, Dooley KE, Caws M, Figaji A, Savic R, Solomons R, Thwaites GE; Tuberculous Meningitis International Research Consortium.

Nat Rev Neurol. 2017 Oct;13(10):581-598. doi: 10.1038/nrneurol.2017.120. Epub 2017 Sep 8. Review.


Weight Rich-Club Analysis in the White Matter Network of Late-Life Depression with Memory Deficits.

Mai N, Zhong X, Chen B, Peng Q, Wu Z, Zhang W, Ouyang C, Ning Y.

Front Aging Neurosci. 2017 Aug 23;9:279. doi: 10.3389/fnagi.2017.00279. eCollection 2017.


International Surviving Sepsis Campaign guidelines 2016: the perspective from low-income and middle-income countries.

Shrestha GS, Kwizera A, Lundeg G, Baelani JI, Azevedo LCP, Pattnaik R, Haniffa R, Gavrilovic S, Mai NTH, Kissoon N, Lodha R, Misango D, Neto AS, Schultz MJ, Dondorp AM, Thevanayagam J, Dünser MW, Alam AKMS, Mukhtar AM, Hashmi M, Ranjit S, Otu A, Gomersall C, Amito J, Vaeza NN, Nakibuuka J, Mujyarugamba P, Estenssoro E, Ospina-Tascón GA, Mohanty S, Mer M.

Lancet Infect Dis. 2017 Sep;17(9):893-895. doi: 10.1016/S1473-3099(17)30453-X. No abstract available.


Endotoxemia induces lung-brain coupling and multi-organ injury following cerebral ischemia-reperfusion.

Mai N, Prifti L, Rininger A, Bazarian H, Halterman MW.

Exp Neurol. 2017 Nov;297:82-91. doi: 10.1016/j.expneurol.2017.07.016. Epub 2017 Jul 28.


Mono-substitution effects on antimicrobial activity of stapled heptapeptides.

Luong HX, Kim DH, Mai NT, Lee BJ, Kim YW.

Arch Pharm Res. 2017 Jun;40(6):713-719. doi: 10.1007/s12272-017-0922-1. Epub 2017 May 25.


Neuropsychiatric Features of Neurosyphilis: Frequency, Relationship with the Severity of Cognitive Impairment and Comparison with Alzheimer Disease.

Zhong X, Shi H, Hou L, Chen B, Peng Q, Chen X, Wu Z, Wang Y, Mai N, Huang X, Ning Y.

Dement Geriatr Cogn Disord. 2017;43(5-6):308-319. doi: 10.1159/000476060. Epub 2017 May 25.


Central Nervous System Infection Diagnosis by Next-Generation Sequencing: A Glimpse Into the Future?

Mai NTH, Phu NH, Nhu LNT, Hong NTT, Hanh NHH, Nguyet LA, Phuong TM, McBride A, Ha DQ, Nghia HDT, Chau NVV, Thwaites G, Tan LV.

Open Forum Infect Dis. 2017 Mar 4;4(2):ofx046. doi: 10.1093/ofid/ofx046. eCollection 2017 Spring.


The SIGLEC14 null allele is associated with Mycobacterium tuberculosis- and BCG-induced clinical and immunologic outcomes.

Graustein AD, Horne DJ, Fong JJ, Schwarz F, Mefford HC, Peterson GJ, Wells RD, Musvosvi M, Shey M, Hanekom WA, Hatherill M, Scriba TJ, Thuong NTT, Mai NTH, Caws M, Bang ND, Dunstan SJ, Thwaites GE, Varki A, Angata T, Hawn TR.

Tuberculosis (Edinb). 2017 May;104:38-45. doi: 10.1016/ Epub 2017 Feb 21.


Progressive cutaneous Cryptococcosis complicated with meningitis in a myasthenia gravis patient on long-term immunosuppressive therapy - a case report.

Huong NTC, Altibi AMA, Hoa NM, Tuan LA, Salman S, Morsy S, Lien NTB, Truong NT, Mai NTH, Hoa PTL, Thang NB, Trung VT.

BMC Infect Dis. 2017 Apr 26;17(1):311. doi: 10.1186/s12879-017-2415-8.


Leukotriene A4 Hydrolase Genotype and HIV Infection Influence Intracerebral Inflammation and Survival From Tuberculous Meningitis.

Thuong NTT, Heemskerk D, Tram TTB, Thao LTP, Ramakrishnan L, Ha VTN, Bang ND, Chau TTH, Lan NH, Caws M, Dunstan SJ, Chau NVV, Wolbers M, Mai NTH, Thwaites GE.

J Infect Dis. 2017 Apr 1;215(7):1020-1028. doi: 10.1093/infdis/jix050.


Geraniol promotes functional recovery and attenuates neuropathic pain in rats with spinal cord injury.

Lv Y, Zhang L, Li N, Mai N, Zhang Y, Pan S.

Can J Physiol Pharmacol. 2017 Dec;95(12):1389-1395. doi: 10.1139/cjpp-2016-0528. Epub 2017 Mar 23.


Steroidal saponins from Datura metel.

Mai NT, Cuc NT, Anh HL, Nhiem NX, Tai BH, Minh CV, Quang TH, Kim KW, Kim YC, Oh H, Kiem PV.

Steroids. 2017 May;121:1-9. doi: 10.1016/j.steroids.2017.02.002. Epub 2017 Feb 22.


Zoonotic Transmission of mcr-1 Colistin Resistance Gene from Small-Scale Poultry Farms, Vietnam.

Trung NV, Matamoros S, Carrique-Mas JJ, Nghia NH, Nhung NT, Chieu TT, Mai HH, van Rooijen W, Campbell J, Wagenaar JA, Hardon A, Mai NT, Hieu TQ, Thwaites G, de Jong MD, Schultsz C, Hoa NT.

Emerg Infect Dis. 2017 Mar;23(3):529-532. doi: 10.3201/eid2303.161553.


Standardized Methods for Enhanced Quality and Comparability of Tuberculous Meningitis Studies.

Marais BJ, Heemskerk AD, Marais SS, van Crevel R, Rohlwink U, Caws M, Meintjes G, Misra UK, Mai NTH, Ruslami R, Seddon JA, Solomons R, van Toorn R, Figaji A, McIlleron H, Aarnoutse R, Schoeman JF, Wilkinson RJ, Thwaites GE; Tuberculous Meningitis International Research Consortium.

Clin Infect Dis. 2017 Feb 15;64(4):501-509. doi: 10.1093/cid/ciw757. Review.


Suboptimal Exposure to Anti-TB Drugs in a TBM/HIV+ Population Is Not Related to Antiretroviral Therapy.

Török ME, Aljayyoussi G, Waterhouse D, Chau T, Mai N, Phu NH, Hien TT, Hope W, Farrar JJ, Ward SA.

Clin Pharmacol Ther. 2018 Mar;103(3):449-457. doi: 10.1002/cpt.646. Epub 2017 Dec 6.


Angiostrongylus cantonensis Is an Important Cause of Eosinophilic Meningitis in Southern Vietnam.

McBride A, Chau TTH, Hong NTT, Mai NTH, Anh NT, Thanh TT, Van TTH, Xuan LT, Sieu TPM, Thai LH, Chuong LV, Sinh DX, Phong ND, Phu NH, Day J, Nghia HDT, Hien TT, Chau NVV, Thwaites G, Tan LV.

Clin Infect Dis. 2017 Jun 15;64(12):1784-1787. doi: 10.1093/cid/cix118.


Fate of Arsenic during Red River Water Infiltration into Aquifers beneath Hanoi, Vietnam.

Postma D, Mai NT, Lan VM, Trang PT, Sø HU, Nhan PQ, Larsen F, Viet PH, Jakobsen R.

Environ Sci Technol. 2017 Jan 17;51(2):838-845. doi: 10.1021/acs.est.6b05065. Epub 2016 Dec 29.


Release of 1,3,5-trinitroperhydro-1,3,5-triazine (RDX) from polymer-bonded explosives (PBXN-109) into water by artificial weathering.

Kumar M, Ladyman MK, Mai N, Temple T, Coulon F.

Chemosphere. 2017 Feb;169:604-608. doi: 10.1016/j.chemosphere.2016.11.107. Epub 2016 Nov 28.


Quality Improvement in the Neonatal ICU.

Hulse JL, Mai NH.

Respir Care. 2016 Dec;61(12):1704-1705. No abstract available.


A polymorphism in human MR1 is associated with mRNA expression and susceptibility to tuberculosis.

Seshadri C, Thuong NT, Mai NT, Bang ND, Chau TT, Lewinsohn DM, Thwaites GE, Dunstan SJ, Hawn TR.

Genes Immun. 2017 Jan;18(1):8-14. doi: 10.1038/gene.2016.41. Epub 2016 Nov 24.


Selectivity switch between FAK and Pyk2: Macrocyclization of FAK inhibitors improves Pyk2 potency.

Farand J, Mai N, Chandrasekhar J, Newby ZE, Van Veldhuizen J, Loyer-Drew J, Venkataramani C, Guerrero J, Kwok A, Li N, Zherebina Y, Wilbert S, Zablocki J, Phillips G, Watkins WJ, Mourey R, Notte GT.

Bioorg Med Chem Lett. 2016 Dec 15;26(24):5926-5930. doi: 10.1016/j.bmcl.2016.10.092. Epub 2016 Nov 2.


Infection control and tuberculosis among health care workers in Viet Nam, 2009-2013: a cross-sectional survey.

Tiemersma EW, Huong NT, Yen PH, Tinh BT, Thuy TT, Van Hung N, Mai NT, Verver S, Gebhard A, Nhung NV.

BMC Infect Dis. 2016 Nov 10;16(1):664.


Recent advances in the diagnosis and management of tuberculous meningitis.

Mai NT, Thwaites GE.

Curr Opin Infect Dis. 2017 Feb;30(1):123-128. doi: 10.1097/QCO.0000000000000331. Review.


Lower Doses of Fructose Extend Lifespan in Caenorhabditis elegans.

Zheng J, Gao C, Wang M, Tran P, Mai N, Finley JW, Heymsfield SB, Greenway FL, Li Z, Heber D, Burton JH, Johnson WD, Laine RA.

J Diet Suppl. 2017 May 4;14(3):264-277. Epub 2016 Sep 28.


Colonization of Enteroaggregative Escherichia coli and Shiga toxin-producing Escherichia coli in chickens and humans in southern Vietnam.

Trung NV, Nhung HN, Carrique-Mas JJ, Mai HH, Tuyen HT, Campbell J, Nhung NT, Van Minh P, Wagenaar JA, Mai NT, Hieu TQ, Schultsz C, Hoa NT.

BMC Microbiol. 2016 Sep 9;16:208. doi: 10.1186/s12866-016-0827-z.

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