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Items: 1 to 50 of 372

1.

Structure-Reactivity Relationships on Substrates and Inhibitors of the Lysine Deacylase Sirtuin 2 from Schistosoma mansoni (SmSirt2).

Monaldi D, Rotili D, Lancelot J, Marek M, Wössner N, Lucidi A, Tomaselli D, Ramos-Morales E, Romier C, Pierce RJ, Mai A, Jung M.

J Med Chem. 2019 Oct 10;62(19):8733-8759. doi: 10.1021/acs.jmedchem.9b00638. Epub 2019 Sep 20.

PMID:
31496251
2.

H19-Dependent Transcriptional Regulation of β3 and β4 Integrins Upon Estrogen and Hypoxia Favors Metastatic Potential in Prostate Cancer.

Bacci L, Aiello A, Ripoli C, Loria R, Pugliese D, Pierconti F, Rotili D, Strigari L, Pinto F, Bassi PF, Mai A, Grassi C, Pontecorvi A, Falcioni R, Farsetti A, Nanni S.

Int J Mol Sci. 2019 Aug 17;20(16). pii: E4012. doi: 10.3390/ijms20164012.

3.

Coastal zone use and migratory behaviour of the southern population of Mugil liza in Brazil.

Mai ACG, Albuquerque CQ, Lemos VM, Schwingel PR, Ceni GF, Saint'Pierre TD, Vieira JP.

J Fish Biol. 2019 Aug 9. doi: 10.1111/jfb.14120. [Epub ahead of print]

PMID:
31397887
4.

Epigenetic polypharmacology: A new frontier for epi-drug discovery.

Tomaselli D, Lucidi A, Rotili D, Mai A.

Med Res Rev. 2019 Jun 20. doi: 10.1002/med.21600. [Epub ahead of print] Review.

PMID:
31218726
5.

Child and adolescent psychiatry training and services in the Middle East region: a current status assessment.

Clausen CE, Bazaid K, Azeem MW, Abdelrahim F, Elgawad AAA, Alamiri B, AlAnsari AM, Alhamzawi A, Al Mai AM, Bakhiet AM, Bashtawi M, Çuhadaroğlu F, Hedar M, Holdar M, Jabr S, Jafri AS, Jumaian A, Moussa S, Osman AH, Razjouyan K, Yanes E, Guerrero A, Skokauskas N; Consortium on Academic Child, Adolescent Psychiatry in the Middle East (CACAP ME).

Eur Child Adolesc Psychiatry. 2019 Jun 12. doi: 10.1007/s00787-019-01360-2. [Epub ahead of print]

PMID:
31190178
6.

Histone Deacetylases Contribute to Excitotoxicity-Triggered Degeneration of Retinal Ganglion Cells In Vivo.

Schlüter A, Aksan B, Fioravanti R, Valente S, Mai A, Mauceri D.

Mol Neurobiol. 2019 Jun 3. doi: 10.1007/s12035-019-01658-x. [Epub ahead of print]

PMID:
31161423
7.

The impacts of dispersal on the competition outcome of multi-patch competition models.

Mai A, Sun GW, Wang L.

Math Biosci Eng. 2019 Mar 27;16(4):2697-2716. doi: 10.3934/mbe.2019134.

8.

Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells.

Zwergel C, Schnekenburger M, Sarno F, Battistelli C, Manara MC, Stazi G, Mazzone R, Fioravanti R, Gros C, Ausseil F, Florean C, Nebbioso A, Strippoli R, Ushijima T, Scotlandi K, Tripodi M, Arimondo PB, Altucci L, Diederich M, Mai A, Valente S.

Clin Epigenetics. 2019 May 6;11(1):68. doi: 10.1186/s13148-019-0663-8.

9.

In search of consciousness: Examining the temporal dynamics of conscious visual perception using MEG time-series data.

Mai AT, Grootswagers T, Carlson TA.

Neuropsychologia. 2019 Jun;129:310-317. doi: 10.1016/j.neuropsychologia.2019.04.015. Epub 2019 Apr 24.

PMID:
31028755
10.

α,γ-Diketocarboxylic Acids and Their Esters Act as Carbonic Anhydrase IX and XII Selective Inhibitors.

Nocentini A, Lucidi A, Perut F, Massa A, Tomaselli D, Gratteri P, Baldini N, Rotili D, Mai A, Supuran CT.

ACS Med Chem Lett. 2019 Feb 19;10(4):661-665. doi: 10.1021/acsmedchemlett.9b00023. eCollection 2019 Apr 11.

PMID:
30996814
11.

Histone deacetylases as an epigenetic pillar for the development of hybrid inhibitors in cancer.

Stazi G, Fioravanti R, Mai A, Mattevi A, Valente S.

Curr Opin Chem Biol. 2019 Jun;50:89-100. doi: 10.1016/j.cbpa.2019.03.002. Epub 2019 Apr 12. Review.

PMID:
30986654
12.

Comparison of the effects of synthetic and plant-derived mTOR regulators on healthy human ovarian cells.

Sirotkin AV, Adamcova E, Rotili D, Mai A, Mlyncek M, Mansour L, Alwasel S, Harrath AH.

Eur J Pharmacol. 2019 Jul 5;854:70-78. doi: 10.1016/j.ejphar.2019.03.048. Epub 2019 Apr 5.

PMID:
30959047
13.

Influence of reaction-induced convection on quorum sensing in enzyme-loaded agarose beads.

Markovic VM, Bánsági T Jr, McKenzie D, Mai A, Pojman JA, Taylor AF.

Chaos. 2019 Mar;29(3):033130. doi: 10.1063/1.5089295.

PMID:
30927847
14.

Non-Invasive Assays of Cochlear Synaptopathy - Candidates and Considerations.

Bharadwaj HM, Mai AR, Simpson JM, Choi I, Heinz MG, Shinn-Cunningham BG.

Neuroscience. 2019 May 21;407:53-66. doi: 10.1016/j.neuroscience.2019.02.031. Epub 2019 Mar 8.

PMID:
30853540
15.

The emerging role of epigenetics in human autoimmune disorders.

Mazzone R, Zwergel C, Artico M, Taurone S, Ralli M, Greco A, Mai A.

Clin Epigenetics. 2019 Feb 26;11(1):34. doi: 10.1186/s13148-019-0632-2. Review.

16.

Value of antigranulocyte scintigraphy with Tc-99m-sulesomab in diagnosing combat-related infections of the musculoskeletal system.

Loessel C, Mai A, Starke M, Vogt D, Stichling M, Willy C.

J R Army Med Corps. 2019 Feb 20. pii: jramc-2019-001172. doi: 10.1136/jramc-2019-001172. [Epub ahead of print]

PMID:
30787111
17.

Statins and Histone Deacetylase Inhibitors Affect Lamin A/C - Histone Deacetylase 2 Interaction in Human Cells.

Mattioli E, Andrenacci D, Mai A, Valente S, Robijns J, De Vos WH, Capanni C, Lattanzi G.

Front Cell Dev Biol. 2019 Jan 31;7:6. doi: 10.3389/fcell.2019.00006. eCollection 2019.

18.

Neisseria gonorrhoeae evades autophagic killing by downregulating CD46-cyt1 and remodeling lysosomes.

Kim WJ, Mai A, Weyand NJ, Rendón MA, Van Doorslaer K, So M.

PLoS Pathog. 2019 Feb 12;15(2):e1007495. doi: 10.1371/journal.ppat.1007495. eCollection 2019 Feb.

19.

Optical Biosensors Based on Silicon-On-Insulator Ring Resonators: A Review.

Steglich P, Hülsemann M, Dietzel B, Mai A.

Molecules. 2019 Jan 31;24(3). pii: E519. doi: 10.3390/molecules24030519. Review.

20.

Histone deacetylase inhibitors exert anti-tumor effects on human adherent and stem-like glioma cells.

Was H, Krol SK, Rotili D, Mai A, Wojtas B, Kaminska B, Maleszewska M.

Clin Epigenetics. 2019 Jan 17;11(1):11. doi: 10.1186/s13148-018-0598-5.

21.

Acute and chronic neurobehavioral effects of the designer drug and bath salt constituent 3,4-methylenedioxypyrovalerone in the rat.

Atehortua-Martinez LA, Masniere C, Campolongo P, Chasseigneaux S, Callebert J, Zwergel C, Mai A, Laplanche JL, Chen H, Etheve-Quelquejeu M, Mégarbane B, Benturquia N.

J Psychopharmacol. 2019 Mar;33(3):392-405. doi: 10.1177/0269881118822151. Epub 2019 Jan 15.

PMID:
30644332
22.

Intergenerational inheritance of high fat diet-induced cardiac lipotoxicity in Drosophila.

Guida MC, Birse RT, Dall'Agnese A, Toto PC, Diop SB, Mai A, Adams PD, Puri PL, Bodmer R.

Nat Commun. 2019 Jan 14;10(1):193. doi: 10.1038/s41467-018-08128-3.

23.

Impacts of the Dispersal Delay on the Stability of the Coexistence Equilibrium of a Two-Patch Predator-Prey Model with Random Predator Dispersal.

Mai A, Sun G, Wang L.

Bull Math Biol. 2019 May;81(5):1337-1351. doi: 10.1007/s11538-018-00568-8. Epub 2019 Jan 9.

PMID:
30627954
24.

Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells.

Stazi G, Battistelli C, Piano V, Mazzone R, Marrocco B, Marchese S, Louie SM, Zwergel C, Antonini L, Patsilinakos A, Ragno R, Viviano M, Sbardella G, Ciogli A, Fabrizi G, Cirilli R, Strippoli R, Marchetti A, Tripodi M, Nomura DK, Mattevi A, Mai A, Valente S.

Eur J Med Chem. 2019 Feb 1;163:722-735. doi: 10.1016/j.ejmech.2018.11.050. Epub 2018 Nov 28.

PMID:
30576903
25.

Application of Small Epigenetic Modulators in Pediatric Medulloblastoma.

Zwergel C, Romanelli A, Stazi G, Besharat ZM, Catanzaro G, Tafani M, Valente S, Mai A.

Front Pediatr. 2018 Dec 3;6:370. doi: 10.3389/fped.2018.00370. eCollection 2018. Review.

26.

The mTORC1/4E-BP/eIF4E Axis Promotes Antibody Class Switching in B Lymphocytes.

Chiu H, Jackson LV, Oh KI, Mai A, Ronai ZA, Ruggero D, Fruman DA.

J Immunol. 2019 Jan 15;202(2):579-590. doi: 10.4049/jimmunol.1800602. Epub 2018 Dec 10.

PMID:
30530594
27.

Effect of α-Methoxy Substitution on the Anti-HIV Activity of Dihydropyrimidin-4(3 H)-ones.

Nawrozkij MB, Forgione M, Yablokov AS, Lucidi A, Tomaselli D, Patsilinakos A, Panella C, Hailu GS, Kirillov IA, Badia R, Riveira-Muñoz E, Crespan E, Armijos Rivera JI, Cirilli R, Ragno R, Esté JA, Maga G, Mai A, Rotili D.

J Med Chem. 2019 Jan 24;62(2):604-621. doi: 10.1021/acs.jmedchem.8b01238. Epub 2018 Dec 20.

PMID:
30525601
28.

The joint impacts of dispersal delay and dispersal patterns on the stability of predator-prey metacommunities.

Mai A, Sun G, Zhang F, Wang L.

J Theor Biol. 2019 Feb 7;462:455-465. doi: 10.1016/j.jtbi.2018.11.035. Epub 2018 Nov 29.

PMID:
30502408
29.

EZH2, HIF-1, and Their Inhibitors: An Overview on Pediatric Cancers.

Papale M, Ferretti E, Battaglia G, Bellavia D, Mai A, Tafani M.

Front Pediatr. 2018 Nov 19;6:328. doi: 10.3389/fped.2018.00328. eCollection 2018. Review.

30.

Identification of novel quinazoline derivatives as potent antiplasmodial agents.

Bouchut A, Rotili D, Pierrot C, Valente S, Lafitte S, Schultz J, Hoglund U, Mazzone R, Lucidi A, Fabrizi G, Pechalrieu D, Arimondo PB, Skinner-Adams TS, Chua MJ, Andrews KT, Mai A, Khalife J.

Eur J Med Chem. 2019 Jan 1;161:277-291. doi: 10.1016/j.ejmech.2018.10.041. Epub 2018 Oct 17.

PMID:
30366254
31.

Six Years (2012-2018) of Researches on Catalytic EZH2 Inhibitors: The Boom of the 2-Pyridone Compounds.

Fioravanti R, Stazi G, Zwergel C, Valente S, Mai A.

Chem Rec. 2018 Dec;18(12):1818-1832. doi: 10.1002/tcr.201800091. Epub 2018 Oct 19. Review.

PMID:
30338896
32.

Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells.

Iachettini S, Trisciuoglio D, Rotili D, Lucidi A, Salvati E, Zizza P, Di Leo L, Del Bufalo D, Ciriolo MR, Leonetti C, Steegborn C, Mai A, Rizzo A, Biroccio A.

Cell Death Dis. 2018 Sep 24;9(10):996. doi: 10.1038/s41419-018-1065-0.

33.

Altered modulation of lamin A/C-HDAC2 interaction and p21 expression during oxidative stress response in HGPS.

Mattioli E, Andrenacci D, Garofalo C, Prencipe S, Scotlandi K, Remondini D, Gentilini D, Di Blasio AM, Valente S, Scarano E, Cicchilitti L, Piaggio G, Mai A, Lattanzi G.

Aging Cell. 2018 Oct;17(5):e12824. doi: 10.1111/acel.12824. Epub 2018 Aug 15. Erratum in: Aging Cell. 2018 Dec;17(6):e12885.

34.

Nucleocytoplasmic export of HDAC5 and SIRT2 downregulation: two epigenetic mechanisms by which antidepressants enhance synaptic plasticity markers.

Muñoz-Cobo I, Erburu MM, Zwergel C, Cirilli R, Mai A, Valente S, Puerta E, Tordera RM.

Psychopharmacology (Berl). 2018 Oct;235(10):2831-2846. doi: 10.1007/s00213-018-4975-8. Epub 2018 Aug 8.

PMID:
30091005
35.

ProLIF - quantitative integrin protein-protein interactions and synergistic membrane effects on proteoliposomes.

De Franceschi N, Miihkinen M, Hamidi H, Alanko J, Mai A, Picas L, Guzmán C, Lévy D, Mattjus P, Goult BT, Goud B, Ivaska J.

J Cell Sci. 2018 Aug 20;132(4). pii: jcs214270. doi: 10.1242/jcs.214270.

36.

Quadratic electro-optic effect in silicon-organic hybrid slot-waveguides.

Steglich P, Mai C, Villringer C, Pulwer S, Casalboni M, Schrader S, Mai A.

Opt Lett. 2018 Aug 1;43(15):3598-3601. doi: 10.1364/OL.43.003598.

PMID:
30067633
37.

Identification of fukinolic acid from Cimicifuga heracleifolia and its derivatives as novel antiviral compounds against enterovirus A71 infection.

Ma Y, Cong W, Huang H, Sun L, Mai AH, Boonen K, Maryam W, De Borggraeve W, Luo G, Liu Q, Schoofs L, Van Kuppeveld F, Neyts J, Mirabelli C, Luyten W.

Int J Antimicrob Agents. 2019 Feb;53(2):128-136. doi: 10.1016/j.ijantimicag.2018.07.014. Epub 2018 Jul 29.

PMID:
30063999
38.

Correction to 'Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells'.

Mellini P, Marrocco B, Borovika D, Polletta L, Carnevale I, Saladini S, Stazi G, Zwergel C, Trapencieris P, Ferretti E, Tafani M, Valente S, Mai A.

Philos Trans R Soc Lond B Biol Sci. 2018 Sep 19;373(1755). pii: 20180305. doi: 10.1098/rstb.2018.0305. No abstract available.

39.

Bioassay-guided isolation of three anthelmintic compounds from Warburgia ugandensis Sprague subspecies ugandensis, and the mechanism of action of polygodial.

Liu M, Kipanga P, Mai AH, Dhondt I, Braeckman BP, De Borggraeve W, Luyten W.

Int J Parasitol. 2018 Sep;48(11):833-844. doi: 10.1016/j.ijpara.2017.11.009. Epub 2018 Jul 18.

PMID:
30031002
40.

Epigenetic Metalloenzymes.

Blanquart C, Linot C, Cartron PF, Tomaselli D, Mai A, Bertrand P.

Curr Med Chem. 2019;26(15):2748-2785. doi: 10.2174/0929867325666180706105903. Review.

PMID:
29984644
41.

A Quinoline-Based DNA Methyltransferase Inhibitor as a Possible Adjuvant in Osteosarcoma Therapy.

Manara MC, Valente S, Cristalli C, Nicoletti G, Landuzzi L, Zwergel C, Mazzone R, Stazi G, Arimondo PB, Pasello M, Guerzoni C, Picci P, Nanni P, Lollini PL, Mai A, Scotlandi K.

Mol Cancer Ther. 2018 Sep;17(9):1881-1892. doi: 10.1158/1535-7163.MCT-17-0818. Epub 2018 Jun 29.

42.

Characterization of Mg-based bimetal treatment of insensitive munition 2,4-dinitroanisole.

Hadnagy E, Mai A, Smolinski B, Braida W, Koutsospyros A.

Environ Sci Pollut Res Int. 2018 Aug;25(24):24403-24416. doi: 10.1007/s11356-018-2493-1. Epub 2018 Jun 16.

PMID:
29909531
43.

Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia.

Singh AA, Petraglia F, Nebbioso A, Yi G, Conte M, Valente S, Mandoli A, Scisciola L, Lindeboom R, Kerstens H, Janssen-Megens EM, Pourfarzad F, Habibi E, Berentsen K, Kim B, Logie C, Heath S, Wierenga ATJ, Clarke L, Flicek P, Jansen JH, Kuijpers T, Yaspo ML, Valle VD, Bernard O, Gut I, Vellenga E, Stunnenberg HG, Mai A, Altucci L, Martens JHA.

Oncotarget. 2018 May 22;9(39):25647-25660. doi: 10.18632/oncotarget.25429. eCollection 2018 May 22.

44.

Combined HAT/EZH2 modulation leads to cancer-selective cell death.

Petraglia F, Singh AA, Carafa V, Nebbioso A, Conte M, Scisciola L, Valente S, Baldi A, Mandoli A, Petrizzi VB, Ingenito C, De Falco S, Cicatiello V, Apicella I, Janssen-Megens EM, Kim B, Yi G, Logie C, Heath S, Ruvo M, Wierenga ATJ, Flicek P, Yaspo ML, Della Valle V, Bernard O, Tomassi S, Novellino E, Feoli A, Sbardella G, Gut I, Vellenga E, Stunnenberg HG, Mai A, Martens JHA, Altucci L.

Oncotarget. 2018 May 22;9(39):25630-25646. doi: 10.18632/oncotarget.25428. eCollection 2018 May 22.

45.

HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal.

Rossi L, Battistelli C, de Turris V, Noce V, Zwergel C, Valente S, Moioli A, Manzione A, Palladino M, Bordoni V, Domenici A, Menè P, Mai A, Tripodi M, Strippoli R.

Sci Rep. 2018 May 31;8(1):8492. doi: 10.1038/s41598-018-26319-2.

46.

Trends of LSD1 inhibitors in viral infections.

Zwergel C, Stazi G, Mai A, Valente S.

Future Med Chem. 2018 May 1;10(10):1133-1136. doi: 10.4155/fmc-2018-0065. Epub 2018 May 22. No abstract available.

47.

Premature Spinal Bone Loss in Women Living with HIV is Associated with Shorter Leukocyte Telomere Length.

Kalyan S, Pick N, Mai A, Murray MCM, Kidson K, Chu J, Albert AYK, Côté HCF, Maan EJ, Goshtasebi A, Money DM, Prior JC.

Int J Environ Res Public Health. 2018 May 18;15(5). pii: E1018. doi: 10.3390/ijerph15051018.

48.

Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells.

Mellini P, Marrocco B, Borovika D, Polletta L, Carnevale I, Saladini S, Stazi G, Zwergel C, Trapencieris P, Ferretti E, Tafani M, Valente S, Mai A.

Philos Trans R Soc Lond B Biol Sci. 2018 Jun 5;373(1748). pii: 20170150. doi: 10.1098/rstb.2017.0150. Erratum in: Philos Trans R Soc Lond B Biol Sci. 2018 Sep 19;373(1755):.

49.

Lysine acetyltransferase inhibitors: structure-activity relationships and potential therapeutic implications.

Fiorentino F, Mai A, Rotili D.

Future Med Chem. 2018 May 1;10(9):1067-1091. doi: 10.4155/fmc-2017-0244. Epub 2018 Apr 20. Review.

PMID:
29676588
50.

KAT3B-p300 and H3AcK18/H3AcK14 levels are prognostic markers for kidney ccRCC tumor aggressiveness and target of KAT inhibitor CPTH2.

Cocco E, Leo M, Canzonetta C, Di Vito S, Mai A, Rotili D, Di Napoli A, Vecchione A, De Nunzio C, Filetici P, Stoppacciaro A.

Clin Epigenetics. 2018 Apr 4;10:44. doi: 10.1186/s13148-018-0473-4. eCollection 2018.

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