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Items: 1 to 50 of 82

1.

Genome Sequences of Three Cluster C Mycobacteriophages, Bipolarisk, Bread, and FudgeTart.

Bowder DM, Gannon BW, Grint KJ, Iltz JT, Koch TM, Mahnke KS, Murnan BD, Osborn AM, Schreiber DM, Su GL, Troester JG, Doyle EL.

Microbiol Resour Announc. 2019 Jul 11;8(28). pii: e00290-19. doi: 10.1128/MRA.00290-19.

2.

Immunosuppressive therapy influences the accelerated age-dependent T-helper cell differentiation in systemic lupus erythematosus remission patients.

Schaier M, Gottschalk C, Uhlmann L, Speer C, Kälble F, Eckstein V, Müller-Tidow C, Meuer S, Mahnke K, Lorenz HM, Zeier M, Steinborn A.

Arthritis Res Ther. 2018 Dec 18;20(1):278. doi: 10.1186/s13075-018-1778-6.

3.

ATP and Its Metabolite Adenosine as Regulators of Dendritic Cell Activity.

Silva-Vilches C, Ring S, Mahnke K.

Front Immunol. 2018 Nov 9;9:2581. doi: 10.3389/fimmu.2018.02581. eCollection 2018. Review.

4.

Production of Extracellular Adenosine by CD73+ Dendritic Cells Is Crucial for Induction of Tolerance in Contact Hypersensitivity Reactions.

Silva-Vilches C, Ring S, Schrader J, Clausen BE, Probst HC, Melchior F, Schild H, Enk A, Mahnke K.

J Invest Dermatol. 2019 Mar;139(3):541-551. doi: 10.1016/j.jid.2018.10.016. Epub 2018 Oct 28.

PMID:
30393085
5.

Dermal CD207-Negative Migratory Dendritic Cells Are Fully Competent to Prime Protective, Skin Homing Cytotoxic T-Lymphocyte Responses.

Hain T, Melchior F, Kamenjarin N, Muth S, Weslati H, Clausen BE, Mahnke K, Silva-Vilches C, Schütze K, Sohl J, Radsak MP, Bündgen G, Bopp T, Danckwardt S, Schild H, Probst HC.

J Invest Dermatol. 2019 Feb;139(2):422-429. doi: 10.1016/j.jid.2018.08.022. Epub 2018 Oct 6.

PMID:
30296420
6.

End-stage renal disease, dialysis, kidney transplantation and their impact on CD4+ T-cell differentiation.

Schaier M, Leick A, Uhlmann L, Kälble F, Morath C, Eckstein V, Ho A, Mueller-Tidow C, Meuer S, Mahnke K, Sommerer C, Zeier M, Steinborn A.

Immunology. 2018 Oct;155(2):211-224. doi: 10.1111/imm.12947. Epub 2018 May 25.

7.

Allergen-Specific Low Zone Tolerance Is Independent of MRP8/14-, TLR4-, TLR7-, and TLR9-Mediated Immune Processes.

Schmidt T, Lorenz N, Raker VK, Schmidgen MI, Mahnke K, Enk A, Roth J, Steinbrink K.

J Invest Dermatol. 2018 Feb;138(2):452-455. doi: 10.1016/j.jid.2017.09.020. Epub 2017 Sep 22. No abstract available.

8.

Expression of CD73 slows down migration of skin dendritic cells, affecting the sensitization phase of contact hypersensitivity reactions in mice.

Neuberger A, Ring S, Silva-Vilches C, Schrader J, Enk A, Mahnke K.

J Dermatol Sci. 2017 Sep;87(3):292-299. doi: 10.1016/j.jdermsci.2017.07.002. Epub 2017 Jul 9.

PMID:
28743609
9.

The role of age-related T-cell differentiation in patients with renal replacement therapy.

Schaier M, Leick A, Uhlmann L, Kälble F, Eckstein V, Ho A, Meuer S, Mahnke K, Sommerer C, Zeier M, Steinborn A.

Immunol Cell Biol. 2017 Nov;95(10):895-905. doi: 10.1038/icb.2017.57. Epub 2017 Jul 19.

PMID:
28722017
10.

Immune Response After Radiofrequency Ablation and Surgical Resection in Nonsmall Cell Lung Cancer.

Schneider T, Hoffmann H, Dienemann H, Herpel E, Heussel CP, Enk AH, Ring S, Mahnke K.

Semin Thorac Cardiovasc Surg. 2016 Summer;28(2):585-592. doi: 10.1053/j.semtcvs.2016.02.008. Epub 2016 Feb 23.

PMID:
28043482
11.

Down-Regulation of CD62L Shedding in T Cells by CD39+ Regulatory T Cells Leads to Defective Sensitization in Contact Hypersensitivity Reactions.

Mahnke K, Useliene J, Ring S, Kage P, Jendrossek V, Robson SC, Bylaite-Bucinskiene M, Steinbrink K, Enk AH.

J Invest Dermatol. 2017 Jan;137(1):106-114. doi: 10.1016/j.jid.2016.08.023. Epub 2016 Sep 10.

12.

Antibody Targeting of "Steady-State" Dendritic Cells Induces Tolerance Mediated by Regulatory T Cells.

Mahnke K, Ring S, Enk AH.

Front Immunol. 2016 Feb 23;7:63. doi: 10.3389/fimmu.2016.00063. eCollection 2016. Review.

13.

TIGIT-CD155 Interactions in Melanoma: A Novel Co-Inhibitory Pathway with Potential for Clinical Intervention.

Mahnke K, Enk AH.

J Invest Dermatol. 2016 Jan;136(1):9-11. doi: 10.1016/j.jid.2015.10.048.

14.

IL-10 downregulates CXCR3 expression on Th1 cells and interferes with their migration to intestinal inflammatory sites.

Wadwa M, Klopfleisch R, Adamczyk A, Frede A, Pastille E, Mahnke K, Hansen W, Geffers R, Lang KS, Buer J, Büning J, Westendorf AM.

Mucosal Immunol. 2016 Sep;9(5):1263-77. doi: 10.1038/mi.2015.132. Epub 2016 Jan 6.

PMID:
26732675
15.

Differentiation of ICOS+ and ICOS- recent thymic emigrant regulatory T cells (RTE T regs) during normal pregnancy, pre-eclampsia and HELLP syndrome.

Wagner MI, Jöst M, Spratte J, Schaier M, Mahnke K, Meuer S, Zeier M, Steinborn A.

Clin Exp Immunol. 2016 Jan;183(1):129-42. doi: 10.1111/cei.12693. Epub 2015 Oct 12.

16.

The role of recent thymic emigrant-regulatory T-cell (RTE-Treg) differentiation during pregnancy.

Wagner MI, Mai C, Schmitt E, Mahnke K, Meuer S, Eckstein V, Ho AD, Schaier M, Zeier M, Spratte J, Fluhr H, Steinborn A.

Immunol Cell Biol. 2015 Nov;93(10):858-67. doi: 10.1038/icb.2015.51. Epub 2015 Apr 27.

PMID:
25915117
17.

Regulatory T cell-derived adenosine induces dendritic cell migration through the Epac-Rap1 pathway.

Ring S, Pushkarevskaya A, Schild H, Probst HC, Jendrossek V, Wirsdörfer F, Ledent C, Robson SC, Enk AH, Mahnke K.

J Immunol. 2015 Apr 15;194(8):3735-44. doi: 10.4049/jimmunol.1401434. Epub 2015 Mar 16.

18.

Opening a niche for therapy: local lymphodepletion helps the immune system to fight melanoma.

Mahnke K, Skorokhod A, Grabbe S, Enk AH.

J Invest Dermatol. 2014 Jul;134(7):1794-1796. doi: 10.1038/jid.2014.100.

19.

The role of regulatory T cell (Treg) subsets in gestational diabetes mellitus.

Schober L, Radnai D, Spratte J, Kisielewicz A, Schmitt E, Mahnke K, Fluhr H, Uhlmann L, Sohn C, Steinborn A.

Clin Exp Immunol. 2014 Jul;177(1):76-85. doi: 10.1111/cei.12300.

20.

Targeting of autoantigens to DEC205⁺ dendritic cells in vivo suppresses experimental allergic encephalomyelitis in mice.

Ring S, Maas M, Nettelbeck DM, Enk AH, Mahnke K.

J Immunol. 2013 Sep 15;191(6):2938-47. doi: 10.4049/jimmunol.1202592. Epub 2013 Aug 14.

21.

Term and preterm labor: decreased suppressive activity and changes in composition of the regulatory T-cell pool.

Schober L, Radnai D, Schmitt E, Mahnke K, Sohn C, Steinborn A.

Immunol Cell Biol. 2012 Nov;90(10):935-44. doi: 10.1038/icb.2012.33. Epub 2012 Jul 3.

PMID:
22751216
22.

Targeting of the hNC16A collagen domain to dendritic cells induces tolerance to human type XVII collagen.

Ettinger M, Gratz IK, Gruber C, Hauser-Kronberger C, Johnson TS, Mahnke K, Thalhamer J, Hintner H, Peckl-Schmid D, Bauer JW.

Exp Dermatol. 2012 May;21(5):395-8. doi: 10.1111/j.1600-0625.2012.01474.x.

PMID:
22509840
23.

Regulatory T cells stimulate B7-H1 expression in myeloid-derived suppressor cells in ret melanomas.

Fujimura T, Ring S, Umansky V, Mahnke K, Enk AH.

J Invest Dermatol. 2012 Apr;132(4):1239-46. doi: 10.1038/jid.2011.416. Epub 2011 Dec 22.

24.

Pregnancy-associated diseases are characterized by the composition of the systemic regulatory T cell (Treg) pool with distinct subsets of Tregs.

Steinborn A, Schmitt E, Kisielewicz A, Rechenberg S, Seissler N, Mahnke K, Schaier M, Zeier M, Sohn C.

Clin Exp Immunol. 2012 Jan;167(1):84-98. doi: 10.1111/j.1365-2249.2011.04493.x.

25.

Non-small cell lung cancer induces an immunosuppressive phenotype of dendritic cells in tumor microenvironment by upregulating B7-H3.

Schneider T, Hoffmann H, Dienemann H, Schnabel PA, Enk AH, Ring S, Mahnke K.

J Thorac Oncol. 2011 Jul;6(7):1162-8. doi: 10.1097/JTO.0b013e31821c421d.

26.

Regulatory T cells from IL-10-deficient mice fail to suppress contact hypersensitivity reactions due to lack of adenosine production.

Ring S, Enk AH, Mahnke K.

J Invest Dermatol. 2011 Jul;131(7):1494-502. doi: 10.1038/jid.2011.50. Epub 2011 Mar 24.

27.

IL-27 renders DC immunosuppressive by induction of B7-H1.

Karakhanova S, Bedke T, Enk AH, Mahnke K.

J Leukoc Biol. 2011 Jun;89(6):837-45. doi: 10.1189/jlb.1209788. Epub 2011 Feb 23.

PMID:
21345970
28.

Myeloid derived suppressor cells and their role in tolerance induction in cancer.

Fujimura T, Mahnke K, Enk AH.

J Dermatol Sci. 2010 Jul;59(1):1-6. doi: 10.1016/j.jdermsci.2010.05.001. Review.

PMID:
20570112
29.

Endothelial cells augment the suppressive function of CD4+ CD25+ Foxp3+ regulatory T cells: involvement of programmed death-1 and IL-10.

Bedke T, Pretsch L, Karakhanova S, Enk AH, Mahnke K.

J Immunol. 2010 May 15;184(10):5562-70. doi: 10.4049/jimmunol.0902458. Epub 2010 Apr 9.

30.

ATP activates regulatory T Cells in vivo during contact hypersensitivity reactions.

Ring S, Enk AH, Mahnke K.

J Immunol. 2010 Apr 1;184(7):3408-16. doi: 10.4049/jimmunol.0901751. Epub 2010 Mar 5.

31.

Gap junctions between regulatory T cells and dendritic cells prevent sensitization of CD8(+) T cells.

Ring S, Karakhanova S, Johnson T, Enk AH, Mahnke K.

J Allergy Clin Immunol. 2010 Jan;125(1):237-46.e1-7. doi: 10.1016/j.jaci.2009.10.025.

PMID:
20109751
32.

Skin melanoma development in ret transgenic mice despite the depletion of CD25+Foxp3+ regulatory T cells in lymphoid organs.

Kimpfler S, Sevko A, Ring S, Falk C, Osen W, Frank K, Kato M, Mahnke K, Schadendorf D, Umansky V.

J Immunol. 2009 Nov 15;183(10):6330-7. doi: 10.4049/jimmunol.0900609. Epub 2009 Oct 19.

33.

Small for gestational age (SGA) neonates show reduced suppressive activity of their regulatory T cells.

Steinborn A, Engst M, Haensch GM, Mahnke K, Schmitt E, Meuer S, Sohn C.

Clin Immunol. 2010 Feb;134(2):188-97. doi: 10.1016/j.clim.2009.09.003. Epub 2009 Nov 26.

PMID:
19837002
34.

ERK/p38 MAP-kinases and PI3K are involved in the differential regulation of B7-H1 expression in DC subsets.

Karakhanova S, Meisel S, Ring S, Mahnke K, Enk AH.

Eur J Immunol. 2010 Jan;40(1):254-66. doi: 10.1002/eji.200939289.

35.

Extracorporeal photophoresis augments function of CD4+CD25+FoxP3+ regulatory T cells by triggering adenosine production.

Schmitt S, Johnson TS, Karakhanova S, Näher H, Mahnke K, Enk AH.

Transplantation. 2009 Aug 15;88(3):411-6. doi: 10.1097/TP.0b013e3181aed927.

PMID:
19667946
36.

CD4+CD25+ regulatory T cells suppress contact hypersensitivity reactions through a CD39, adenosine-dependent mechanism.

Ring S, Oliver SJ, Cronstein BN, Enk AH, Mahnke K.

J Allergy Clin Immunol. 2009 Jun;123(6):1287-96.e2. doi: 10.1016/j.jaci.2009.03.022. Epub 2009 May 8.

PMID:
19427686
37.

Naturally occurring short splice variant of CYLD positively regulates dendritic cell function.

Srokowski CC, Masri J, Hövelmeyer N, Krembel AK, Tertilt C, Strand D, Mahnke K, Massoumi R, Waisman A, Schild H.

Blood. 2009 Jun 4;113(23):5891-5. doi: 10.1182/blood-2008-08-175489. Epub 2009 Apr 2.

PMID:
19342479
38.

Myeloid dendritic cell: From sentinel of immunity to key player of peripheral tolerance?

Steinbrink K, Mahnke K, Grabbe S, Enk AH, Jonuleit H.

Hum Immunol. 2009 May;70(5):289-93. doi: 10.1016/j.humimm.2009.02.003. Epub 2009 Feb 13. Review.

PMID:
19217922
39.

Inhibition of melanoma growth by targeting of antigen to dendritic cells via an anti-DEC-205 single-chain fragment variable molecule.

Johnson TS, Mahnke K, Storn V, Schönfeld K, Ring S, Nettelbeck DM, Haisma HJ, Le Gall F, Kontermann RE, Enk AH.

Clin Cancer Res. 2008 Dec 15;14(24):8169-77. doi: 10.1158/1078-0432.CCR-08-1474.

40.

Distinct subsets of regulatory T cells during pregnancy: is the imbalance of these subsets involved in the pathogenesis of preeclampsia?

Steinborn A, Haensch GM, Mahnke K, Schmitt E, Toermer A, Meuer S, Sohn C.

Clin Immunol. 2008 Dec;129(3):401-12. doi: 10.1016/j.clim.2008.07.032. Epub 2008 Sep 21.

PMID:
18805741
41.

Interaction of regulatory T cells with antigen-presenting cells in health and disease.

Mahnke K, Ring S, Bedke T, Karakhanova S, Enk A.

Chem Immunol Allergy. 2008;94:29-39. doi: 10.1159/000154854. Review.

PMID:
18802334
42.

Constitutive crosspresentation of tissue antigens by dendritic cells controls CD8+ T cell tolerance in vivo.

Luckashenak N, Schroeder S, Endt K, Schmidt D, Mahnke K, Bachmann MF, Marconi P, Deeg CA, Brocker T.

Immunity. 2008 Apr;28(4):521-32. doi: 10.1016/j.immuni.2008.02.018.

43.

Regulatory conversation between antigen presenting cells and regulatory T cells enhance immune suppression.

Mahnke K, Bedke T, Enk AH.

Cell Immunol. 2007 Nov-Dec;250(1-2):1-13. doi: 10.1016/j.cellimm.2008.01.004. Epub 2008 Mar 3. Review.

PMID:
18313653
44.

Expanded murine regulatory T cells: analysis of phenotype and function in contact hypersensitivity reactions.

Ring S, Thome M, Pretsch L, Enk AH, Mahnke K.

J Immunol Methods. 2007 Sep 30;326(1-2):10-21. Epub 2007 Jul 16.

PMID:
17689553
45.

Induction of immunosuppressive functions of dendritic cells in vivo by CD4+CD25+ regulatory T cells: role of B7-H3 expression and antigen presentation.

Mahnke K, Ring S, Johnson TS, Schallenberg S, Schönfeld K, Storn V, Bedke T, Enk AH.

Eur J Immunol. 2007 Aug;37(8):2117-26.

46.

Tolerogenic dendritic cells and regulatory T cells: a two-way relationship.

Mahnke K, Johnson TS, Ring S, Enk AH.

J Dermatol Sci. 2007 Jun;46(3):159-67. Epub 2007 Apr 10. Review.

PMID:
17428639
47.

Depletion of CD4+CD25+ human regulatory T cells in vivo: kinetics of Treg depletion and alterations in immune functions in vivo and in vitro.

Mahnke K, Schönfeld K, Fondel S, Ring S, Karakhanova S, Wiedemeyer K, Bedke T, Johnson TS, Storn V, Schallenberg S, Enk AH.

Int J Cancer. 2007 Jun 15;120(12):2723-33.

48.
49.

On the edge of autoimmunity: T-cell stimulation by steady-state dendritic cells prevents autoimmune diabetes.

Bruder D, Westendorf AM, Hansen W, Prettin S, Gruber AD, Qian Y, von Boehmer H, Mahnke K, Buer J.

Diabetes. 2005 Dec;54(12):3395-401.

50.

Targeting of antigens to activated dendritic cells in vivo cures metastatic melanoma in mice.

Mahnke K, Qian Y, Fondel S, Brueck J, Becker C, Enk AH.

Cancer Res. 2005 Aug 1;65(15):7007-12.

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