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Items: 26


The functional synergism of microRNA clustering provides therapeutically relevant epigenetic interference in glioblastoma.

Bhaskaran V, Nowicki MO, Idriss M, Jimenez MA, Lugli G, Hayes JL, Mahmoud AB, Zane RE, Passaro C, Ligon KL, Haas-Kogan D, Bronisz A, Godlewski J, Lawler SE, Chiocca EA, Peruzzi P.

Nat Commun. 2019 Jan 25;10(1):442. doi: 10.1038/s41467-019-08390-z.


NKR-P1B expression in gut-associated innate lymphoid cells is required for the control of gastrointestinal tract infections.

Abou-Samra E, Hickey Z, Aguilar OA, Scur M, Mahmoud AB, Pyatibrat S, Tu MM, Francispillai J, Mortha A, Carlyle JR, Rahim MMA, Makrigiannis AP.

Cell Mol Immunol. 2018 Oct 1. doi: 10.1038/s41423-018-0169-x. [Epub ahead of print]


Critical role for the Ly49 family of class I MHC receptors in adaptive natural killer cell responses.

Wight A, Mahmoud AB, Scur M, Tu MM, Rahim MMA, Sad S, Makrigiannis AP.

Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):11579-11584. doi: 10.1073/pnas.1722374115. Epub 2018 Sep 24.


Junctional ectopic tachycardia following tetralogy of fallot repair in children under 2 years.

Ismail MF, Arafat AA, Hamouda TE, El Tantawy AE, Edrees A, Bogis A, Badawy N, Mahmoud AB, Elmahrouk AF, Jamjoom AA.

J Cardiothorac Surg. 2018 Jun 5;13(1):60. doi: 10.1186/s13019-018-0749-y.


Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles.

Ricklefs FL, Alayo Q, Krenzlin H, Mahmoud AB, Speranza MC, Nakashima H, Hayes JL, Lee K, Balaj L, Passaro C, Rooj AK, Krasemann S, Carter BS, Chen CC, Steed T, Treiber J, Rodig S, Yang K, Nakano I, Lee H, Weissleder R, Breakefield XO, Godlewski J, Westphal M, Lamszus K, Freeman GJ, Bronisz A, Lawler SE, Chiocca EA.

Sci Adv. 2018 Mar 7;4(3):eaar2766. doi: 10.1126/sciadv.aar2766. eCollection 2018 Mar.


Immunosurveillance and Immunoediting of Breast Cancer via Class I MHC Receptors.

Tu MM, Rahim MMA, Sayed C, Mahmoud AB, Makrigiannis AP.

Cancer Immunol Res. 2017 Nov;5(11):1016-1028. doi: 10.1158/2326-6066.CIR-17-0056. Epub 2017 Sep 18.


A Viral Immunoevasin Controls Innate Immunity by Targeting the Prototypical Natural Killer Cell Receptor Family.

Aguilar OA, Berry R, Rahim MMA, Reichel JJ, Popović B, Tanaka M, Fu Z, Balaji GR, Lau TNH, Tu MM, Kirkham CL, Mahmoud AB, Mesci A, Krmpotić A, Allan DSJ, Makrigiannis AP, Jonjić S, Rossjohn J, Carlyle JR.

Cell. 2017 Mar 23;169(1):58-71.e14. doi: 10.1016/j.cell.2017.03.002.


NK-Cell Recruitment Is Necessary for Eradication of Peritoneal Carcinomatosis with an IL12-Expressing Maraba Virus Cellular Vaccine.

Alkayyal AA, Tai LH, Kennedy MA, de Souza CT, Zhang J, Lefebvre C, Sahi S, Ananth AA, Mahmoud AB, Makrigiannis AP, Cron GO, Macdonald B, Marginean EC, Stojdl DF, Bell JC, Auer RC.

Cancer Immunol Res. 2017 Mar;5(3):211-221. doi: 10.1158/2326-6066.CIR-16-0162. Epub 2017 Feb 3.


Correction: Influenza Virus Targets Class I MHC-Educated NK Cells for Immunoevasion.

Mahmoud AB, Tu MM, Wight A, Zein HS, Rahim MM, Lee SH, Sekhon HS, Brown EG, Makrigiannis AP.

PLoS Pathog. 2016 Nov 4;12(11):e1006021. doi: 10.1371/journal.ppat.1006021. eCollection 2016 Nov. Erratum in: PLoS Pathog. 2016 Dec 16;12 (12 ):e1006105.


Expansion and Protection by a Virus-Specific NK Cell Subset Lacking Expression of the Inhibitory NKR-P1B Receptor during Murine Cytomegalovirus Infection.

Rahim MM, Wight A, Mahmoud AB, Aguilar OA, Lee SH, Vidal SM, Carlyle JR, Makrigiannis AP.

J Immunol. 2016 Sep 15;197(6):2325-37. doi: 10.4049/jimmunol.1600776. Epub 2016 Aug 10.


Licensed and Unlicensed NK Cells: Differential Roles in Cancer and Viral Control.

Tu MM, Mahmoud AB, Makrigiannis AP.

Front Immunol. 2016 May 2;7:166. doi: 10.3389/fimmu.2016.00166. eCollection 2016. Review.


Influenza Virus Targets Class I MHC-Educated NK Cells for Immunoevasion.

Mahmoud AB, Tu MM, Wight A, Zein HS, Rahim MM, Lee SH, Sekhon HS, Brown EG, Makrigiannis AP.

PLoS Pathog. 2016 Feb 29;12(2):e1005446. doi: 10.1371/journal.ppat.1005446. eCollection 2016 Feb. Erratum in: PLoS Pathog. 2016 Nov 4;12 (11):e1006021.


The mouse NKR-P1B:Clr-b recognition system is a negative regulator of innate immune responses.

Rahim MM, Chen P, Mottashed AN, Mahmoud AB, Thomas MJ, Zhu Q, Brooks CG, Kartsogiannis V, Gillespie MT, Carlyle JR, Makrigiannis AP.

Blood. 2015 Apr 2;125(14):2217-27. doi: 10.1182/blood-2014-02-556142. Epub 2015 Jan 22.


Ly49 family receptors are required for cancer immunosurveillance mediated by natural killer cells.

Tu MM, Mahmoud AB, Wight A, Mottashed A, Bélanger S, Rahim MM, Abou-Samra E, Makrigiannis AP.

Cancer Res. 2014 Jul 15;74(14):3684-94. doi: 10.1158/0008-5472.CAN-13-3021. Epub 2014 May 6.


SPG7 variant escapes phosphorylation-regulated processing by AFG3L2, elevates mitochondrial ROS, and is associated with multiple clinical phenotypes.

Almontashiri NA, Chen HH, Mailloux RJ, Tatsuta T, Teng AC, Mahmoud AB, Ho T, Stewart NA, Rippstein P, Harper ME, Roberts R, Willenborg C, Erdmann J; CARDIoGRAM Consortium, Pastore A, McBride HM, Langer T, Stewart AF.

Cell Rep. 2014 May 8;7(3):834-47. doi: 10.1016/j.celrep.2014.03.051. Epub 2014 Apr 24.


Ly49 receptors: innate and adaptive immune paradigms.

Rahim MM, Tu MM, Mahmoud AB, Wight A, Abou-Samra E, Lima PD, Makrigiannis AP.

Front Immunol. 2014 Apr 2;5:145. doi: 10.3389/fimmu.2014.00145. eCollection 2014. Review.


Maraba MG1 virus enhances natural killer cell function via conventional dendritic cells to reduce postoperative metastatic disease.

Zhang J, Tai LH, Ilkow CS, Alkayyal AA, Ananth AA, de Souza CT, Wang J, Sahi S, Ly L, Lefebvre C, Falls TJ, Stephenson KB, Mahmoud AB, Makrigiannis AP, Lichty BD, Bell JC, Stojdl DF, Auer RC.

Mol Ther. 2014 Jul;22(7):1320-1332. doi: 10.1038/mt.2014.60. Epub 2014 Apr 3.


Optimized tetramer analysis reveals Ly49 promiscuity for MHC ligands.

McFall E, Tu MM, Al-Khattabi N, Tai LH, St-Laurent AS, Tzankova V, Hall CW, Belanger S, Troke AD, Wight A, Mahmoud AB, Zein HS, Rahim MM, Carlyle JR, Makrigiannis AP.

J Immunol. 2013 Dec 1;191(11):5722-9. doi: 10.4049/jimmunol.1300726. Epub 2013 Oct 23.


Perioperative influenza vaccination reduces postoperative metastatic disease by reversing surgery-induced dysfunction in natural killer cells.

Tai LH, Zhang J, Scott KJ, de Souza CT, Alkayyal AA, Ananth AA, Sahi S, Adair RA, Mahmoud AB, Sad S, Bell JC, Makrigiannis AP, Melcher AA, Auer RC.

Clin Cancer Res. 2013 Sep 15;19(18):5104-15. doi: 10.1158/1078-0432.CCR-13-0246. Epub 2013 Jul 23.


Ly49Q positively regulates type I IFN production by plasmacytoid dendritic cells in an immunoreceptor tyrosine-based inhibitory motif-dependent manner.

Rahim MM, Tai LH, Troke AD, Mahmoud AB, Abou-Samra E, Roy JG, Mottashed A, Ault N, Corbeil C, Goulet ML, Zein HS, Hamilton-Valensky M, Krystal G, Kerr WG, Toyama-Sorimachi N, Makrigiannis AP.

J Immunol. 2013 Apr 15;190(8):3994-4004. doi: 10.4049/jimmunol.1200873. Epub 2013 Mar 11.


Impaired natural killer cell self-education and "missing-self" responses in Ly49-deficient mice.

Bélanger S, Tu MM, Rahim MM, Mahmoud AB, Patel R, Tai LH, Troke AD, Wilhelm BT, Landry JR, Zhu Q, Tung KS, Raulet DH, Makrigiannis AP.

Blood. 2012 Jul 19;120(3):592-602. doi: 10.1182/blood-2012-02-408732. Epub 2012 Jun 1. Erratum in: Blood. 2013 Oct 3;122(14):2525.


Diagnostic value of hepatic intercellular adhesion molecule-1 expression in Egyptian infants with biliary atresia and other forms of neonatal cholestasis.

Ghoneim EM, Sira MM, Abd Elaziz AM, Khalil FO, Sultan MM, Mahmoud AB.

Hepatol Res. 2011 Aug;41(8):763-75. doi: 10.1111/j.1872-034X.2011.00832.x.


Venovenous malformation: a common finding after Kawashima operation.

Mahmoud AB, Zahrani S, Bahaidarah SA, Kouatli AA, Baslaim GM.

Eur J Cardiothorac Surg. 2011 Feb;39(2):222-7. doi: 10.1016/j.ejcts.2010.04.034. Epub 2010 Jun 11.


Hemolytic anemia: an unusual presentation of cor triatriatum sinistrum.

Mahmoud AB, Jamjoom AA, Kouatli AA, Bayoumy MS.

Interact Cardiovasc Thorac Surg. 2009 Aug;9(2):382-3. doi: 10.1510/icvts.2008.201293. Epub 2009 May 7.


Propranolol: a new indication for an old drug in preventing postoperative junctional ectopic tachycardia after surgical repair of tetralogy of Fallot.

Mahmoud AB, Tantawy AE, Kouatli AA, Baslaim GM.

Interact Cardiovasc Thorac Surg. 2008 Apr;7(2):184-7. Epub 2007 Dec 18.


Effect of modified ultrafiltration on pulmonary function after cardiopulmonary bypass.

Mahmoud AB, Burhani MS, Hannef AA, Jamjoom AA, Al-Githmi IS, Baslaim GM.

Chest. 2005 Nov;128(5):3447-53.


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