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Items: 8


An oligoclonal antibody durably overcomes resistance of lung cancer to third-generation EGFR inhibitors.

Mancini M, Gal H, Gaborit N, Mazzeo L, Romaniello D, Salame TM, Lindzen M, Mahlknecht G, Enuka Y, Burton DG, Roth L, Noronha A, Marrocco I, Adreka D, Altstadter RE, Bousquet E, Downward J, Maraver A, Krizhanovsky V, Yarden Y.

EMBO Mol Med. 2018 Feb;10(2):294-308. doi: 10.15252/emmm.201708076.


Multimerization of ERBB2/HER2 specific aptamer leads to improved receptor binding.

Mahlknecht G, Maron R, Schechter B, Yarden Y, Sela M.

Biochem Biophys Res Commun. 2015 Sep 18;465(2):218-24. doi: 10.1016/j.bbrc.2015.07.157. Epub 2015 Aug 4.


Aptamer Targeting the ERBB2 Receptor Tyrosine Kinase for Applications in Tumor Therapy.

Mahlknecht G, Sela M, Yarden Y.

Methods Mol Biol. 2015;1317:3-15. doi: 10.1007/978-1-4939-2727-2_1.


Inhibition of pancreatic carcinoma by homo- and heterocombinations of antibodies against EGF-receptor and its kin HER2/ErbB-2.

Maron R, Schechter B, Mancini M, Mahlknecht G, Yarden Y, Sela M.

Proc Natl Acad Sci U S A. 2013 Sep 17;110(38):15389-94. doi: 10.1073/pnas.1313857110. Epub 2013 Sep 3.


Aptamer to ErbB-2/HER2 enhances degradation of the target and inhibits tumorigenic growth.

Mahlknecht G, Maron R, Mancini M, Schechter B, Sela M, Yarden Y.

Proc Natl Acad Sci U S A. 2013 May 14;110(20):8170-5. doi: 10.1073/pnas.1302594110. Epub 2013 Apr 29.


Simultaneous Inhibition of Estrogen Receptor and the HER2 Pathway in Breast Cancer: Effects of HER2 Abundance.

Emde A, Mahlknecht G, Maslak K, Ribba B, Sela M, Possinger K, Yarden Y.

Transl Oncol. 2011 Oct;4(5):293-300. Epub 2011 Oct 1.


Generation and characterization of peptide mimotopes specific for anti ErbB-2 monoclonal antibodies.

Witsch EJ, Mahlknecht G, Wakim J, Sertchook R, Bublil E, Yarden Y, Sela M.

Int Immunol. 2011 Jun;23(6):391-403. doi: 10.1093/intimm/dxr028. Epub 2011 May 19.


Measuring the osmotic water permeability of the plant protoplast plasma membrane: implication of the nonosmotic volume.

Sommer A, Mahlknecht G, Obermeyer G.

J Membr Biol. 2007 Feb;215(2-3):111-23. Epub 2007 Jun 14.

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