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A new era in pediatric heart allocation: Keeping our house in order.

Mao CY, Mahle WT.

Am J Transplant. 2019 Sep 17. doi: 10.1111/ajt.15596. [Epub ahead of print]


Hospital readmission following pediatric heart transplantation.

Mahle WT, Mason KL, Dipchand AI, Richmond M, Feingold B, Canter CE, Hsu DT, Singh TP, Shaddy RE, Armstrong BD, Zeevi A, Iklé DN, Diop H, Odim J, Webber SA; CTOTC-04 Investigators.

Pediatr Transplant. 2019 Sep 4:e13561. doi: 10.1111/petr.13561. [Epub ahead of print]


Corticosteroid Therapy in Neonates Undergoing Cardiopulmonary Bypass: Randomized Controlled Trial.

Graham EM, Martin RH, Buckley JR, Zyblewski SC, Kavarana MN, Bradley SM, Alsoufi B, Mahle WT, Hassid M, Atz AM.

J Am Coll Cardiol. 2019 Aug 6;74(5):659-668. doi: 10.1016/j.jacc.2019.05.060.


Early outcomes for low-risk pediatric heart transplant recipients and steroid avoidance: A multicenter cohort study (Clinical Trials in Organ Transplantation in Children - CTOTC-04).

Lamour JM, Mason KL, Hsu DT, Feingold B, Blume ED, Canter CE, Dipchand AI, Shaddy RE, Mahle WT, Zuckerman WA, Bentlejewski C, Armstrong BD, Morrison Y, Diop H, Iklé DN, Odim J, Zeevi A, Webber SA; CTOTC-04 investigators.

J Heart Lung Transplant. 2019 Sep;38(9):972-981. doi: 10.1016/j.healun.2019.06.006. Epub 2019 Jun 20.


Commentary: Window of brain protection after congenital heart surgery-Is it still open?

Mahle WT.

J Thorac Cardiovasc Surg. 2019 Sep;158(3):880-881. doi: 10.1016/j.jtcvs.2019.03.070. Epub 2019 Apr 4. No abstract available.


The Bayley-III scale may underestimate neurodevelopmental disability after cardiac surgery in infants†.

Goldstone AB, Baiocchi M, Wypij D, Stopp C, Andropoulos DB, Atallah J, Atz AM, Beca J, Donofrio MT, Duncan K, Ghanayem NS, Goldberg CS, Hövels-Gürich H, Ichida F, Jacobs JP, Justo R, Latal B, Li JS, Mahle WT, McQuillen PS, Menon SC, Pike NA, Pizarro C, Shekerdemian LS, Synnes A, Williams IA, Bellinger DC, Newburger J, Gaynor JW.

Eur J Cardiothorac Surg. 2019 Apr 21. pii: ezz123. doi: 10.1093/ejcts/ezz123. [Epub ahead of print]


Association of intraoperative circulating-brain injury biomarker and neurodevelopmental outcomes at 1 year among neonates who have undergone cardiac surgery.

Graham EM, Martin RH, Atz AM, Hamlin-Smith K, Kavarana MN, Bradley SM, Alsoufi B, Mahle WT, Everett AD.

J Thorac Cardiovasc Surg. 2019 May;157(5):1996-2002. doi: 10.1016/j.jtcvs.2019.01.040. Epub 2019 Jan 23.


Variation in Implementation and Outcomes of Early Extubation Practices After Infant Cardiac Surgery.

Bates KE, Mahle WT, Bush L, Donohue J, Gaies MG, Nicolson SC, Shekerdemian L, Witte M, Wolf M, Shea JA, Likosky DS, Pasquali SK.

Ann Thorac Surg. 2019 May;107(5):1434-1440. doi: 10.1016/j.athoracsur.2018.11.031. Epub 2018 Dec 14.


Hospital Costs Related to Early Extubation After Infant Cardiac Surgery.

McHugh KE, Mahle WT, Hall MA, Scheurer MA, Moga MA, Triedman J, Nicolson SC, Amula V, Cooper DS, Schamberger M, Wolf M, Shekerdemian L, Burns KM, Ash KE, Hipp DM, Pasquali SK; Pediatric Heart Network Investigators.

Ann Thorac Surg. 2019 May;107(5):1421-1426. doi: 10.1016/j.athoracsur.2018.10.019. Epub 2018 Nov 17.


Sustainability of Infant Cardiac Surgery Early Extubation Practices After Implementation and Study.

Gaies M, Pasquali SK, Nicolson SC, Shekerdemian L, Witte M, Wolf M, Zhang W, Donohue JE, Mahle WT; Pediatric Heart Network Investigators.

Ann Thorac Surg. 2019 May;107(5):1427-1433. doi: 10.1016/j.athoracsur.2018.09.024. Epub 2018 Oct 31.


Posterior Cerebellar Volume and Executive Function in Young Adults With Congenital Heart Disease.

Semmel ES, Dotson VM, Burns TG, Mahle WT, King TZ.

J Int Neuropsychol Soc. 2018 Oct;24(9):939-948. doi: 10.1017/S1355617718000310. Epub 2018 May 30.


Association of Preoperative Cell Counts With Outcomes After Operation for Congenital Heart Disease.

Jones SM, McCracken C, Alsoufi B, Mahle WT, Oster ME.

Ann Thorac Surg. 2018 Oct;106(4):1234-1240. doi: 10.1016/j.athoracsur.2018.04.022. Epub 2018 May 16.


Heart failure after the Norwood procedure: An analysis of the Single Ventricle Reconstruction Trial.

Mahle WT, Hu C, Trachtenberg F, Menteer J, Kindel SJ, Dipchand AI, Richmond ME, Daly KP, Henderson HT, Lin KY, McCulloch M, Lal AK, Schumacher KR, Jacobs JP, Atz AM, Villa CR, Burns KM, Newburger JW; Pediatric Heart Network Investigators.

J Heart Lung Transplant. 2018 Jul;37(7):879-885. doi: 10.1016/j.healun.2018.02.009. Epub 2018 Feb 16.


New Paradigms for Pulmonary Vein Stenosis Treatment: When Surgery and Transcatheter Therapy Aren't Good Enough.

Kanaan UB, Mahle WT.

J Pediatr. 2018 Jul;198:12-13. doi: 10.1016/j.jpeds.2018.01.082. Epub 2018 Mar 15. No abstract available.


Neutropenia in pediatric heart transplant recipients.

Rose-Felker K, Mukhtar A, Kelleman MS, Deshpande SR, Mahle WT.

Pediatr Transplant. 2018 May;22(3):e13130. doi: 10.1111/petr.13130. Epub 2018 Feb 23.


Study rationale, design, and pretransplantation alloantibody status: A first report of Clinical Trials in Organ Transplantation in Children-04 (CTOTC-04) in pediatric heart transplantation.

Zuckerman WA, Zeevi A, Mason KL, Feingold B, Bentlejewski C, Addonizio LJ, Blume ED, Canter CE, Dipchand AI, Hsu DT, Shaddy RE, Mahle WT, Demetris AJ, Briscoe DM, Mohanakumar T, Ahearn JM, Iklé DN, Armstrong BD, Morrison Y, Diop H, Odim J, Webber SA.

Am J Transplant. 2018 Sep;18(9):2135-2147. doi: 10.1111/ajt.14695. Epub 2018 Mar 23.


Incidence, characterization, and impact of newly detected donor-specific anti-HLA antibody in the first year after pediatric heart transplantation: A report from the CTOTC-04 study.

Dipchand AI, Webber S, Mason K, Feingold B, Bentlejewski C, Mahle WT, Shaddy R, Canter C, Blume ED, Lamour J, Zuckerman W, Diop H, Morrison Y, Armstrong B, Ikle D, Odim J, Zeevi A; CTOTC-04 Investigators.

Am J Transplant. 2018 Sep;18(9):2163-2174. doi: 10.1111/ajt.14691. Epub 2018 Mar 24.


Transplant-Free Survival and Interventions at 6 Years in the SVR Trial.

Newburger JW, Sleeper LA, Gaynor JW, Hollenbeck-Pringle D, Frommelt PC, Li JS, Mahle WT, Williams IA, Atz AM, Burns KM, Chen S, Cnota J, Dunbar-Masterson C, Ghanayem NS, Goldberg CS, Jacobs JP, Lewis AB, Mital S, Pizarro C, Eckhauser A, Stark P, Ohye RG; Pediatric Heart Network Investigators.

Circulation. 2018 May 22;137(21):2246-2253. doi: 10.1161/CIRCULATIONAHA.117.029375. Epub 2018 Feb 1.


Biventricular support with HeartWare ventricular assist device in a pediatric patient.

Deshpande SR, Carroll MM, Mao C, Mahle WT, Kanter K.

Pediatr Transplant. 2018 Feb;22(1). doi: 10.1111/petr.13037. Epub 2017 Dec 1.


Utilisation of early intervention services in young children with hypoplastic left heart syndrome.

Mussatto KA, Hollenbeck-Pringle D, Trachtenberg F, Sood E, Sananes R, Pike NA, Lambert LM, Mahle WT, Goldberg DJ, Goldberg CS, Dunbar-Masterson C, Otto M, Marino BS, Bartle BH, Williams IA, Jacobs JP, Zyblewski SC, Pemberton VL.

Cardiol Young. 2018 Jan;28(1):126-133. doi: 10.1017/S104795111700169X. Epub 2017 Aug 29.


Management of Cardiac Involvement Associated With Neuromuscular Diseases: A Scientific Statement From the American Heart Association.

Feingold B, Mahle WT, Auerbach S, Clemens P, Domenighetti AA, Jefferies JL, Judge DP, Lal AK, Markham LW, Parks WJ, Tsuda T, Wang PJ, Yoo SJ; American Heart Association Pediatric Heart Failure Committee of the Council on Cardiovascular Disease in the Young; Council on Clinical Cardiology; Council on Cardiovascular Radiology and Intervention; Council on Functional Genomics and Translational Biology; and Stroke Council.

Circulation. 2017 Sep 26;136(13):e200-e231. doi: 10.1161/CIR.0000000000000526. Epub 2017 Aug 24.


Adrenergic receptor genotypes influence postoperative outcomes in infants in the Single-Ventricle Reconstruction Trial.

Ramroop R, Manase G, Lu D, Manase D, Chen S, Kim R, Lee T, Mahle WT, McHugh K, Mitchell M, Tristani-Firouzi M, Wechsler SB, Wilder NS, Zak V, Lafreniere-Roula M, Newburger JW, Gaynor JW, Russell MW, Mital S.

J Thorac Cardiovasc Surg. 2017 Nov;154(5):1703-1710.e3. doi: 10.1016/j.jtcvs.2017.06.041. Epub 2017 Jun 24.


2017 ACC/AAP/AHA Health Policy Statement on Opportunities and Challenges in Pediatric Drug Development: Learning From Sildenafil.

Sable CA, Ivy DD, Beekman RH 3rd, Clayton-Jeter HD, Jenkins KJ, Mahle WT, Morrow WR, Murphy MD, Nelson RM, Rosenthal GL, Stockbridge N, Wessel DL.

J Am Coll Cardiol. 2017 Jul 25;70(4):495-503. doi: 10.1016/j.jacc.2017.04.007. Epub 2017 Jun 29. No abstract available. Erratum in: J Am Coll Cardiol. 2017 Sep 5;70(10):1309.


2017 ACC/AAP/AHA Health Policy Statement on Opportunities and Challenges in Pediatric Drug Development: Learning From Sildenafil.

Sable CA, Ivy DD, Beekman RH 3rd, Clayton-Jeter HD, Jenkins KJ, Mahle WT, Morrow WR, Murphy MD, Nelson RM, Rosenthal GL, Stockbridge N, Wessel DL.

Circ Cardiovasc Qual Outcomes. 2017 Jul;10(7). pii: e000026. doi: 10.1161/HCQ.0000000000000026. Review. No abstract available. Erratum in: Circ Cardiovasc Qual Outcomes. 2017 Nov;10(11):e000035.


Bacterial infections after pediatric heart transplantation: Epidemiology, risk factors and outcomes.

Rostad CA, Wehrheim K, Kirklin JK, Naftel D, Pruitt E, Hoffman TM, L'Ecuyer T, Berkowitz K, Mahle WT, Scheel JN.

J Heart Lung Transplant. 2017 Sep;36(9):996-1003. doi: 10.1016/j.healun.2017.05.009. Epub 2017 May 11.


Adult Chest Pain in the Pediatric Emergency Department: Treatment and Timeliness From Door In To Door Out.

Sacks JH, Flueckiger PB, Spandorfer PR, Mahle WT, Costello BE.

Pediatr Emerg Care. 2017 Nov;33(11):740-744. doi: 10.1097/PEC.0000000000001081.


The prevalence and effects of aspiration among neonates at the time of discharge.

Karsch E, Irving SY, Aylward BS, Mahle WT.

Cardiol Young. 2017 Sep;27(7):1241-1247. doi: 10.1017/S104795111600278X. Epub 2017 Feb 6.


Sickle Cell Disease with Cyanotic Congenital Heart Disease: Long-Term Outcomes in 5 Children.

Iannucci GJ, Adisa OA, Oster ME, McConnell M, Mahle WT.

Tex Heart Inst J. 2016 Dec 1;43(6):509-513. doi: 10.14503/THIJ-15-5610. eCollection 2016 Dec.


Use of sirolimus in pediatric heart transplant patients: A multi-institutional study from the Pediatric Heart Transplant Study Group.

Rossano JW, Jefferies JL, Pahl E, Naftel DC, Pruitt E, Lupton K, Dreyer WJ, Chinnock R, Boyle G, Mahle WT; Pediatric Heart Transplant Study Investigators.

J Heart Lung Transplant. 2017 Apr;36(4):427-433. doi: 10.1016/j.healun.2016.09.009. Epub 2016 Oct 4.


Closing in on the PumpKIN Trial of the Jarvik 2015 Ventricular Assist Device.

Baldwin JT, Adachi I, Teal J, Almond CA, Jaquiss RD, Massicotte MP, Dasse K, Siami FS, Zak V, Kaltman JR, Mahle WT, Jarvik R.

Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2017 Jan;20:9-15. doi: 10.1053/j.pcsu.2016.09.003. Review.


The Effect of Noncardiac and Genetic Abnormalities on Outcomes Following Neonatal Congenital Heart Surgery.

Alsoufi B, Gillespie S, Mahle WT, Deshpande S, Kogon B, Maher K, Kanter K.

Semin Thorac Cardiovasc Surg. 2016 Spring;28(1):105-14. doi: 10.1053/j.semtcvs.2015.10.016. Epub 2015 Nov 17.


Utilizing a Collaborative Learning Model to Promote Early Extubation Following Infant Heart Surgery.

Mahle WT, Nicolson SC, Hollenbeck-Pringle D, Gaies MG, Witte MK, Lee EK, Goldsworthy M, Stark PC, Burns KM, Scheurer MA, Cooper DS, Thiagarajan R, Sivarajan VB, Colan SD, Schamberger MS, Shekerdemian LS; Pediatric Heart Network Investigators.

Pediatr Crit Care Med. 2016 Oct;17(10):939-947. Erratum in: Pediatr Crit Care Med. 2018 Apr;19(4):386-387.


A multi-institutional evaluation of antibody-mediated rejection utilizing the Pediatric Heart Transplant Study database: Incidence, therapies and outcomes.

Thrush PT, Pahl E, Naftel DC, Pruitt E, Everitt MD, Missler H, Zangwill S, Burch M, Hoffman TM, Butts R, Mahle WT.

J Heart Lung Transplant. 2016 Dec;35(12):1497-1504. doi: 10.1016/j.healun.2016.06.014. Epub 2016 Jun 24.


Early Extubation After Repair of Tetralogy of Fallot and the Fontan Procedure: An Analysis of The Society of Thoracic Surgeons Congenital Heart Surgery Database.

Mahle WT, Jacobs JP, Jacobs ML, Kim S, Kirshbom PM, Pasquali SK, Austin EH, Kanter KR, Nicolson SC, Hill KD.

Ann Thorac Surg. 2016 Sep;102(3):850-858. doi: 10.1016/j.athoracsur.2016.03.013. Epub 2016 May 10.


Emerging Research Directions in Adult Congenital Heart Disease: A Report From an NHLBI/ACHA Working Group.

Gurvitz M, Burns KM, Brindis R, Broberg CS, Daniels CJ, Fuller SM, Honein MA, Khairy P, Kuehl KS, Landzberg MJ, Mahle WT, Mann DL, Marelli A, Newburger JW, Pearson GD, Starling RC, Tringali GR, Valente AM, Wu JC, Califf RM.

J Am Coll Cardiol. 2016 Apr 26;67(16):1956-64. doi: 10.1016/j.jacc.2016.01.062. Review.


Era effect on survival following paediatric heart transplantation.

Alsoufi B, Deshpande S, McCracken C, Kogon B, Vincent R, Mahle WT, Kanter K.

Eur J Cardiothorac Surg. 2016 Oct;50(4):742-751. Epub 2016 Mar 31.


Rationale and methodology of a collaborative learning project in congenital cardiac care.

Wolf MJ, Lee EK, Nicolson SC, Pearson GD, Witte MK, Huckaby J, Gaies M, Shekerdemian LS, Mahle WT; Pediatric Heart Network Investigators.

Am Heart J. 2016 Apr;174:129-37. doi: 10.1016/j.ahj.2016.01.013. Epub 2016 Jan 23. Review.


fMRI investigation of working memory in adolescents with surgically treated congenital heart disease.

King TZ, Smith KM, Burns TG, Sun B, Shin J, Jones RA, Drossner D, Mahle WT.

Appl Neuropsychol Child. 2017 Jan-Mar;6(1):7-21. doi: 10.1080/21622965.2015.1065185. Epub 2016 Mar 17.


Late primary transplantation in complex congenital heart disease.

Deshpande SR, Shehata BM, Sallee D, Kogon BE, Mahle WT.

Pediatr Transplant. 2016 Mar;20(2):325-8. doi: 10.1111/petr.12676. Epub 2016 Jan 25.


Association of Digoxin With Interstage Mortality: Results From the Pediatric Heart Network Single Ventricle Reconstruction Trial Public Use Dataset.

Oster ME, Kelleman M, McCracken C, Ohye RG, Mahle WT.

J Am Heart Assoc. 2016 Jan 13;5(1). pii: e002566. doi: 10.1161/JAHA.115.002566.


Syncope Best Practices: A Syncope Clinical Practice Guideline to Improve Quality.

Phelps HM, Sachdeva R, Mahle WT, McCracken CE, Kelleman M, McConnell M, Fischbach PS, Cardis BM, Campbell RM, Oster ME.

Congenit Heart Dis. 2016 May;11(3):230-8. doi: 10.1111/chd.12324. Epub 2015 Dec 18.


Outcomes of heart transplantation in children with hypoplastic left heart syndrome previously palliated with the Norwood procedure.

Alsoufi B, Mahle WT, Manlhiot C, Deshpande S, Kogon B, McCrindle BW, Kanter K.

J Thorac Cardiovasc Surg. 2016 Jan;151(1):167-74, 175.e1-2. doi: 10.1016/j.jtcvs.2015.09.081. Epub 2015 Sep 28.


Selective management strategy of interrupted aortic arch mitigates left ventricular outflow tract obstruction risk.

Alsoufi B, Schlosser B, McCracken C, Sachdeva R, Kogon B, Border W, Mahle WT, Kanter K.

J Thorac Cardiovasc Surg. 2016 Feb;151(2):412-20. doi: 10.1016/j.jtcvs.2015.09.060. Epub 2015 Sep 28.


A Little Sugar Never Hurt Anyone: Hyperglycemia after Infant Heart Surgery.

Mahle WT.

J Pediatr. 2015 Dec;167(6):1185-6. doi: 10.1016/j.jpeds.2015.09.002. Epub 2015 Sep 26. No abstract available.


White Matter Integrity Dissociates Verbal Memory and Auditory Attention Span in Emerging Adults with Congenital Heart Disease.

Brewster RC, King TZ, Burns TG, Drossner DM, Mahle WT.

J Int Neuropsychol Soc. 2015 Jan;21(1):22-33. doi: 10.1017/S135561771400109X.


Congenital Heart Defects and Receipt of Special Education Services.

Riehle-Colarusso T, Autry A, Razzaghi H, Boyle CA, Mahle WT, Van Naarden Braun K, Correa A.

Pediatrics. 2015 Sep;136(3):496-504. doi: 10.1542/peds.2015-0259. Epub 2015 Aug 17.


Improved Detection of Cardiac Allograft Vasculopathy: A Multi-Institutional Analysis of Functional Parameters in Pediatric Heart Transplant Recipients.

Kindel SJ, Law YM, Chin C, Burch M, Kirklin JK, Naftel DC, Pruitt E, Carboni MP, Arens A, Atz AM, Dreyer WJ, Mahle WT, Pahl E.

J Am Coll Cardiol. 2015 Aug 4;66(5):547-57. doi: 10.1016/j.jacc.2015.05.063.


Extracorporeal Membrane Oxygenation as a Bridge to Pediatric Heart Transplantation: Effect on Post-Listing and Post-Transplantation Outcomes.

Dipchand AI, Mahle WT, Tresler M, Naftel DC, Almond C, Kirklin JK, Pruitt E, Webber SA; Pediatric Heart Transplant Study Investigators.

Circ Heart Fail. 2015 Sep;8(5):960-9. doi: 10.1161/CIRCHEARTFAILURE.114.001553. Epub 2015 Jul 23.


Impact of Leukocyte Function-Associated Antigen-1 Blockade on Endogenous Allospecific T Cells to Multiple Minor Histocompatibility Antigen Mismatched Cardiac Allograft.

Kwun J, Farris AB, Song H, Mahle WT, Burlingham WJ, Knechtle SJ.

Transplantation. 2015 Dec;99(12):2485-93. doi: 10.1097/TP.0000000000000805.


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