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Items: 17

1.

Organophosphorus Inhibition and Characterization of Recombinant Guinea Pig Acetylcholinesterase.

Ruark CD, Chapleau RR, Mahle DA, Gearhart JM.

Protein Pept Lett. 2015;22(10):862-8.

PMID:
26216268
2.

Predicting passive and active tissue:plasma partition coefficients: interindividual and interspecies variability.

Ruark CD, Hack CE, Robinson PJ, Mahle DA, Gearhart JM.

J Pharm Sci. 2014 Jul;103(7):2189-2198. doi: 10.1002/jps.24011. Epub 2014 May 15.

PMID:
24832575
3.

Age-dependent partition coefficients for a mixture of volatile organic solvents in Sprague-Dawley rats and humans.

Mahle DA, Gearhart JM, Grigsby CC, Mattie DR, Barton HA, Lipscomb JC, Cook RS.

J Toxicol Environ Health A. 2007 Oct;70(20):1745-51.

PMID:
17885931
4.

Predicting age-appropriate pharmacokinetics of six volatile organic compounds in the rat utilizing physiologically based pharmacokinetic modeling.

Rodriguez CE, Mahle DA, Gearhart JM, Mattie DR, Lipscomb JC, Cook RS, Barton HA.

Toxicol Sci. 2007 Jul;98(1):43-56. Epub 2007 Apr 10.

PMID:
17426107
5.

A quantitative description of suicide inhibition of dichloroacetic acid in rats and mice.

Keys DA, Schultz IR, Mahle DA, Fisher JW.

Toxicol Sci. 2004 Dec;82(2):381-93. Epub 2004 Sep 16.

PMID:
15375292
6.

Predicting neonatal perchlorate dose and inhibition of iodide uptake in the rat during lactation using physiologically-based pharmacokinetic modeling.

Clewell RA, Merrill EA, Yu KO, Mahle DA, Sterner TR, Fisher JW, Gearhart JM.

Toxicol Sci. 2003 Aug;74(2):416-36. Epub 2003 Jun 12.

PMID:
12805655
7.

Changes in cross-fostered Sprague-Dawley rat litters exposed to perchlorate.

Mahle DA, Yu KO, Narayanan L, Mattie DR, Fisher JW.

Int J Toxicol. 2003 Mar-Apr;22(2):87-94.

PMID:
12745989
8.

Predicting fetal perchlorate dose and inhibition of iodide kinetics during gestation: a physiologically-based pharmacokinetic analysis of perchlorate and iodide kinetics in the rat.

Clewell RA, Merrill EA, Yu KO, Mahle DA, Sterner TR, Mattie DR, Robinson PJ, Fisher JW, Gearhart JM.

Toxicol Sci. 2003 Jun;73(2):235-55. Epub 2003 Apr 15.

PMID:
12700398
9.

The pharmacokinetics of perchlorate and its effect on the hypothalamus-pituitary-thyroid axis in the male rat.

Yu KO, Narayanan L, Mattie DR, Godfrey RJ, Todd PN, Sterner TR, Mahle DA, Lumpkin MH, Fisher JW.

Toxicol Appl Pharmacol. 2002 Jul 15;182(2):148-59.

PMID:
12140178
10.

In vivo kinetics of trichloroacetate in male Fischer 344 rats.

Yu KO, Barton HA, Mahle DA, Frazier JM.

Toxicol Sci. 2000 Apr;54(2):302-11.

PMID:
10774812
11.

A species comparison of chloral hydrate metabolism in blood and liver.

Lipscomb JC, Mahle DA, Brashear WT, Garrett CM.

Biochem Biophys Res Commun. 1996 Oct 14;227(2):340-50.

PMID:
8878519
12.

Dichloroacetic acid: metabolism in cytosol.

Lipscomb JC, Mahle DA, Brashear WT, Barton HA.

Drug Metab Dispos. 1995 Nov;23(11):1202-5.

PMID:
8591719
13.

Gas uptake studies of deuterium isotope effects on dichloromethane metabolism in female B6C3F1 mice in vivo.

Andersen ME, Clewell HJ 3rd, Mahle DA, Gearhart JM.

Toxicol Appl Pharmacol. 1994 Sep;128(1):158-65.

PMID:
8079349
14.

A partition coefficient determination method for nonvolatile chemicals in biological tissues.

Jepson GW, Hoover DK, Black RK, McCafferty JD, Mahle DA, Gearhart JM.

Fundam Appl Toxicol. 1994 May;22(4):519-24.

PMID:
7520010
15.

Variability of physiologically based pharmacokinetic (PBPK) model parameters and their effects on PBPK model predictions in a risk assessment for perchloroethylene (PCE).

Gearhart JM, Mahle DA, Greene RJ, Seckel CS, Flemming CD, Fisher JW, Clewell HJ 3rd.

Toxicol Lett. 1993 May;68(1-2):131-44.

PMID:
8516760
16.

Structural determination of the carboxylic acid metabolites of polychlorotrifluoroethylene.

Brashear WT, Greene RJ, Mahle DA.

Xenobiotica. 1992 May;22(5):499-506. Erratum in: Xenobiotica 1992 Nov;22(11):1354.

PMID:
1413865
17.

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