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Items: 31

1.

Metabolomics of the Wolfram Syndrome 1 Gene (Wfs1) Deficient Mice.

Porosk R, Terasmaa A, Mahlapuu R, Soomets U, Kilk K.

OMICS. 2017 Dec;21(12):721-732. doi: 10.1089/omi.2017.0143.

PMID:
29257731
2.

Glutathione system in Wolfram syndrome 1‑deficient mice.

Porosk R, Kilk K, Mahlapuu R, Terasmaa A, Soomets U.

Mol Med Rep. 2017 Nov;16(5):7092-7097. doi: 10.3892/mmr.2017.7419. Epub 2017 Aug 31.

PMID:
28901522
3.

Inflammatory, cardio-metabolic and diabetic profiling of chronic schizophrenia.

Balõtšev R, Koido K, Vasar V, Janno S, Kriisa K, Mahlapuu R, Ljubajev U, Parksepp M, Veiksaar P, Volke V, Lang A, Haring L, Zilmer M, Vasar E.

Eur Psychiatry. 2017 Jan;39:1-10. doi: 10.1016/j.eurpsy.2016.05.010. Epub 2016 Nov 1.

PMID:
27810612
4.

Investigation of the surfactant type and concentration effect on the retention factors of glutathione and its analogues by micellar electrokinetic chromatography.

Kazarjan J, Mahlapuu R, Hansen M, Soomets U, Kaljurand M, Vaher M.

J Sep Sci. 2015 Oct;38(19):3461-8. doi: 10.1002/jssc.201500567. Epub 2015 Aug 21. Erratum in: J Sep Sci. 2016 Jan;39(1):234.

PMID:
26200325
5.

Impact of probiotic Lactobacillus plantarum TENSIA in different dairy products on anthropometric and blood biochemical indices of healthy adults.

Hütt P, Songisepp E, Rätsep M, Mahlapuu R, Kilk K, Mikelsaar M.

Benef Microbes. 2015;6(3):233-43. doi: 10.3920/BM2014.0035.

PMID:
25524863
6.

Wfs1-deficient animals have brain-region-specific changes of Na+, K+-ATPase activity and mRNA expression of α1 and β1 subunits.

Sütt S, Altpere A, Reimets R, Visnapuu T, Loomets M, Raud S, Salum T, Mahlapuu R, Kairane C, Zilmer M, Vasar E.

J Neurosci Res. 2015 Mar;93(3):530-7. doi: 10.1002/jnr.23508. Epub 2014 Nov 10.

PMID:
25385034
7.

Alterations of bronchial epithelial metabolome by cigarette smoke are reversible by an antioxidant, O-methyl-L-tyrosinyl-γ-L-glutamyl-L-cysteinylglycine.

Aug A, Altraja A, Altraja S, Laaniste L, Mahlapuu R, Soomets U, Kilk K.

Am J Respir Cell Mol Biol. 2014 Oct;51(4):586-94. doi: 10.1165/rcmb.2013-0377OC.

PMID:
24810251
8.

Male infertility: decreased levels of selenium, zinc and antioxidants.

Türk S, Mändar R, Mahlapuu R, Viitak A, Punab M, Kullisaar T.

J Trace Elem Med Biol. 2014 Apr;28(2):179-85. doi: 10.1016/j.jtemb.2013.12.005. Epub 2013 Dec 31.

PMID:
24462254
9.
10.

Separation of glutathione and its novel analogues and determination of their dissociation constants by capillary electrophoresis.

Kazarjan J, Vaher M, Mahlapuu R, Hansen M, Soomets U, Kaljurand M.

Electrophoresis. 2013 Jun;34(12):1820-7. doi: 10.1002/elps.201200611. Epub 2013 May 23.

PMID:
23580455
11.

Cigarette smoke-induced differential regulation of glutathione metabolism in bronchial epithelial cells is balanced by an antioxidant tetrapeptide UPF1.

Altraja S, Mahlapuu R, Soomets U, Altraja A.

Exp Toxicol Pathol. 2013 Sep;65(6):711-7. doi: 10.1016/j.etp.2012.09.005. Epub 2012 Oct 11.

PMID:
23062287
12.

Mitochondrial oxidative stress index, activity of redox-sensitive aconitase and effects of endogenous anti- and pro-oxidants on its activity in control, Alzheimer's disease and Swedish Familial Alzheimer's disease brain.

Raukas M, Rebane R, Mahlapuu R, Jefremov V, Zilmer K, Karelson E, Bogdanovic N, Zilmer M.

Free Radic Res. 2012 Dec;46(12):1490-5. doi: 10.3109/10715762.2012.728286. Epub 2012 Sep 27.

PMID:
22962855
13.

Diverse Effects of Glutathione and UPF Peptides on Antioxidant Defense System in Human Erythroleukemia Cells K562.

Kairane C, Mahlapuu R, Ehrlich K, Kilk K, Zilmer M, Soomets U.

Int J Pept. 2012;2012:124163. doi: 10.1155/2012/124163. Epub 2012 Feb 15.

14.

Monitoring the redox cycle of low-molecular peptides using a modified target plate in MALDI-MS.

Borissova M, Mahlapuu R, Vaher M.

Talanta. 2010 Nov 15;83(1):274-80. doi: 10.1016/j.talanta.2010.08.022. Epub 2010 Aug 21.

PMID:
21035675
15.

Immunological, antioxidative, and morphological response in combined treatment of ofloxacin and Lactobacillus fermentum ME-3 probiotic in Salmonella Typhimurium murine model.

Truusalu K, Kullisaar T, Hütt P, Mahlapuu R, Aunapuu M, Arend A, Zilmer M, Mikelsaar RH, Mikelsaar M.

APMIS. 2010 Nov;118(11):864-72. doi: 10.1111/j.1600-0463.2010.02672.x. Epub 2010 Sep 14.

PMID:
20955459
16.

Temperature dependence of the sodium pump is altered in the cerebral cortex of CCK2 receptor-deficient mice.

Salum T, Kõks S, Kairane C, Mahlapuu R, Zilmer M, Vasar E.

Neurochem Res. 2010 May;35(5):688-92. doi: 10.1007/s11064-009-0119-1. Epub 2010 Jan 8.

PMID:
20058075
17.

Analysis of in vitro toxicity of five cell-penetrating peptides by metabolic profiling.

Kilk K, Mahlapuu R, Soomets U, Langel U.

Toxicology. 2009 Nov 30;265(3):87-95. doi: 10.1016/j.tox.2009.09.016. Epub 2009 Sep 30.

PMID:
19799958
18.

Mechanism and stoichiometry of 2,2-diphenyl-1-picrylhydrazyl radical scavenging by glutathione and its novel alpha-glutamyl derivative.

Viirlaid S, Mahlapuu R, Kilk K, Kuznetsov A, Soomets U, Järv J.

Bioorg Chem. 2009 Aug;37(4):126-32. doi: 10.1016/j.bioorg.2009.05.001. Epub 2009 May 12.

PMID:
19487009
19.

Characterization of UPF peptides, members of the glutathione analogues library, on the basis of their effects on oxidative stress-related enzymes.

Ehrlich K, Ida K, Mahlapuu R, Kairane C, Oit I, Zilmer M, Soomets U.

Free Radic Res. 2009 Jun;43(6):572-80. doi: 10.1080/10715760902918691.

PMID:
19424927
20.

Relation of exploratory behaviour to plasma corticosterone and Wfs1 gene expression in Wistar rats.

Sütt S, Raud S, Abramov U, Innos J, Luuk H, Plaas M, Kõks S, Zilmer K, Mahlapuu R, Zilmer M, Vasar E.

J Psychopharmacol. 2010 Jun;24(6):905-13. doi: 10.1177/0269881109102738. Epub 2009 Apr 3.

PMID:
19346280
21.

Oxidative stress due to (R)-styrene oxide exposure and the role of antioxidants in non-Swiss albino (NSA) mice.

Meszka-Jordan A, Mahlapuu R, Soomets U, Carlson GP.

J Toxicol Environ Health A. 2009;72(10):642-50. doi: 10.1080/15287390902769436.

PMID:
19308849
22.

17beta-Oestradiol stimulation of G-proteins in aged and Alzheimer's human brain: comparison with phytoestrogens.

Jefremov V, Rakitin A, Mahlapuu R, Zilmer K, Bogdanovic N, Zilmer M, Karelson E.

J Neuroendocrinol. 2008 May;20(5):587-96. doi: 10.1111/j.1365-2826.2008.01696.x. Epub 2008 Mar 15.

PMID:
18363809
23.

Design, synthesis and properties of novel powerful antioxidants, glutathione analogues.

Ehrlich K, Viirlaid S, Mahlapuu R, Saar K, Kullisaar T, Zilmer M, Langel U, Soomets U.

Free Radic Res. 2007 Jul;41(7):779-87.

PMID:
17577738
24.

Comparison of the stability of glutathione and related synthetic tetrapeptides by HPLC and capillary electrophoresis.

Mahlapuu R, Vaher M, Ehrlich K, Kaljurand M, Soomets U.

J Pept Sci. 2006 Dec;12(12):796-9.

PMID:
17131291
25.

Characterization of the antioxidative activity of novel nontoxic neuropeptides by using capillary electrophoresis.

Vaher M, Viirlaid S, Ehrlich K, Mahlapuu R, Jarvet J, Soomets U, Kaljurand M.

Electrophoresis. 2006 Jul;27(13):2582-9.

PMID:
16732619
26.

An antioxidant tetrapeptide UPF1 in rats has a neuroprotective effect in transient global brain ischemia.

Põder P, Zilmer M, Starkopf J, Kals J, Talonpoika A, Pulges A, Langel U, Kullisaar T, Viirlaid S, Mahlapuu R, Zarkovski A, Arend A, Soomets U.

Neurosci Lett. 2004 Nov 3;370(1):45-50.

PMID:
15489015
27.

Amyloid precursor protein carboxy-terminal fragments modulate G-proteins and adenylate cyclase activity in Alzheimer's disease brain.

Mahlapuu R, Viht K, Balaspiri L, Bogdanovic N, Saar K, Soomets U, Land T, Zilmer M, Karelson E, Langel U.

Brain Res Mol Brain Res. 2003 Sep 10;117(1):73-82.

PMID:
14499483
28.

Possible signaling by glutathione and its novel analogue through potent stimulation of fontocortical G proteins in normal aging and in Alzheimer's disease.

Karelson E, Mahlapuu R, Zilmer M, Soomets U, Bogdanovic N, Langel U.

Ann N Y Acad Sci. 2002 Nov;973:537-40.

PMID:
12485924
29.

Anticonvulsant activity of a nonpeptide galanin receptor agonist.

Saar K, Mazarati AM, Mahlapuu R, Hallnemo G, Soomets U, Kilk K, Hellberg S, Pooga M, Tolf BR, Shi TS, Hökfelt T, Wasterlain C, Bartfai T, Langel U.

Proc Natl Acad Sci U S A. 2002 May 14;99(10):7136-41.

30.

Characterisation of a new chimeric ligand for galanin receptors: galanin(1-13)-[D-Trp(32)]-neuropeptide Y(25-36)amide.

Saar K, Mahlapuu R, Laidmäe E, Valkna A, Kahl U, Karelson E, Langel U.

Regul Pept. 2001 Oct 15;102(1):15-9.

PMID:
11600206
31.

Regulation of GTPase and adenylate cyclase activity by amyloid beta-peptide and its fragments in rat brain tissue.

Soomets U, Mahlapuu R, Tehranian R, Jarvet J, Karelson E, Zilmer M, Iverfeldt K, Zorko M, Gräslund A, Langel U.

Brain Res. 1999 Dec 11;850(1-2):179-88.

PMID:
10629763

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