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Items: 20

1.

Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation.

Nagashima H, Mahlakõiv T, Shih HY, Davis FP, Meylan F, Huang Y, Harrison OJ, Yao C, Mikami Y, Urban JF Jr, Caron KM, Belkaid Y, Kanno Y, Artis D, O'Shea JJ.

Immunity. 2019 Jul 16. pii: S1074-7613(19)30279-1. doi: 10.1016/j.immuni.2019.06.009. [Epub ahead of print]

PMID:
31353223
2.

Stromal cells maintain immune cell homeostasis in adipose tissue via production of interleukin-33.

Mahlakõiv T, Flamar AL, Johnston LK, Moriyama S, Putzel GG, Bryce PJ, Artis D.

Sci Immunol. 2019 May 3;4(35). pii: eaax0416. doi: 10.1126/sciimmunol.aax0416.

PMID:
31053655
3.

IFN-λ prevents influenza virus spread from the upper airways to the lungs and limits virus transmission.

Klinkhammer J, Schnepf D, Ye L, Schwaderlapp M, Gad HH, Hartmann R, Garcin D, Mahlakõiv T, Staeheli P.

Elife. 2018 Apr 13;7. pii: e33354. doi: 10.7554/eLife.33354.

4.

Erratum: The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation.

Wallrapp A, Riesenfeld SJ, Burkett PR, Abdulnour RE, Nyman J, Dionne D, Hofree M, Cuoco MS, Rodman C, Farouq D, Haas BJ, Tickle TL, Trombetta JJ, Baral P, Klose CSN, Mahlakõiv T, Artis D, Rozenblatt-Rosen O, Chiu IM, Levy BD, Kowalczyk MS, Regev A, Kuchroo VK.

Nature. 2017 Nov 30;551(7682):658. doi: 10.1038/nature24480. Epub 2017 Nov 15.

PMID:
29143821
5.

The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation.

Wallrapp A, Riesenfeld SJ, Burkett PR, Abdulnour RE, Nyman J, Dionne D, Hofree M, Cuoco MS, Rodman C, Farouq D, Haas BJ, Tickle TL, Trombetta JJ, Baral P, Klose CSN, Mahlakõiv T, Artis D, Rozenblatt-Rosen O, Chiu IM, Levy BD, Kowalczyk MS, Regev A, Kuchroo VK.

Nature. 2017 Sep 21;549(7672):351-356. doi: 10.1038/nature24029. Epub 2017 Sep 13. Erratum in: Nature. 2017 Nov 15;:.

6.

The neuropeptide neuromedin U stimulates innate lymphoid cells and type 2 inflammation.

Klose CSN, Mahlakõiv T, Moeller JB, Rankin LC, Flamar AL, Kabata H, Monticelli LA, Moriyama S, Putzel GG, Rakhilin N, Shen X, Kostenis E, König GM, Senda T, Carpenter D, Farber DL, Artis D.

Nature. 2017 Sep 14;549(7671):282-286. doi: 10.1038/nature23676. Epub 2017 Sep 6.

7.

Allergen Exposure: When Timing Is Everything.

Mahlakõiv T, Artis D.

Immunity. 2016 Dec 20;45(6):1188-1190. doi: 10.1016/j.immuni.2016.12.007.

8.

Host microbiota constantly control maturation and function of microglia in the CNS.

Erny D, Hrabě de Angelis AL, Jaitin D, Wieghofer P, Staszewski O, David E, Keren-Shaul H, Mahlakoiv T, Jakobshagen K, Buch T, Schwierzeck V, Utermöhlen O, Chun E, Garrett WS, McCoy KD, Diefenbach A, Staeheli P, Stecher B, Amit I, Prinz M.

Nat Neurosci. 2015 Jul;18(7):965-77. doi: 10.1038/nn.4030. Epub 2015 Jun 1.

9.

Interferon-λ and interleukin 22 act synergistically for the induction of interferon-stimulated genes and control of rotavirus infection.

Hernández PP, Mahlakoiv T, Yang I, Schwierzeck V, Nguyen N, Guendel F, Gronke K, Ryffel B, Hoelscher C, Dumoutier L, Renauld JC, Suerbaum S, Staeheli P, Diefenbach A.

Nat Immunol. 2015 Jul;16(7):698-707. doi: 10.1038/ni.3180. Epub 2015 May 25.

10.

Intestinal intraepithelial lymphocyte activation promotes innate antiviral resistance.

Swamy M, Abeler-Dörner L, Chettle J, Mahlakõiv T, Goubau D, Chakravarty P, Ramsay G, Reis E Sousa C, Staeheli P, Blacklaws BA, Heeney JL, Hayday AC.

Nat Commun. 2015 May 19;6:7090. doi: 10.1038/ncomms8090.

11.

Leukocyte-derived IFN-α/β and epithelial IFN-λ constitute a compartmentalized mucosal defense system that restricts enteric virus infections.

Mahlakõiv T, Hernandez P, Gronke K, Diefenbach A, Staeheli P.

PLoS Pathog. 2015 Apr 7;11(4):e1004782. doi: 10.1371/journal.ppat.1004782. eCollection 2015 Apr.

12.

Identification of continuous human B-cell epitopes in the VP35, VP40, nucleoprotein and glycoprotein of Ebola virus.

Becquart P, Mahlakõiv T, Nkoghe D, Leroy EM.

PLoS One. 2014 Jun 10;9(6):e96360. doi: 10.1371/journal.pone.0096360. eCollection 2014.

13.

STAT1β is not dominant negative and is capable of contributing to gamma interferon-dependent innate immunity.

Semper C, Leitner NR, Lassnig C, Parrini M, Mahlakõiv T, Rammerstorfer M, Lorenz K, Rigler D, Müller S, Kolbe T, Vogl C, Rülicke T, Staeheli P, Decker T, Müller M, Strobl B.

Mol Cell Biol. 2014 Jun;34(12):2235-48. doi: 10.1128/MCB.00295-14. Epub 2014 Apr 7.

14.

Human but not mouse hepatocytes respond to interferon-lambda in vivo.

Hermant P, Demarez C, Mahlakõiv T, Staeheli P, Meuleman P, Michiels T.

PLoS One. 2014 Jan 31;9(1):e87906. doi: 10.1371/journal.pone.0087906. eCollection 2014.

15.

Type I and type III interferons drive redundant amplification loops to induce a transcriptional signature in influenza-infected airway epithelia.

Crotta S, Davidson S, Mahlakoiv T, Desmet CJ, Buckwalter MR, Albert ML, Staeheli P, Wack A.

PLoS Pathog. 2013;9(11):e1003773. doi: 10.1371/journal.ppat.1003773. Epub 2013 Nov 21.

16.

Combined action of type I and type III interferon restricts initial replication of severe acute respiratory syndrome coronavirus in the lung but fails to inhibit systemic virus spread.

Mahlakõiv T, Ritz D, Mordstein M, DeDiego ML, Enjuanes L, Müller MA, Drosten C, Staeheli P.

J Gen Virol. 2012 Dec;93(Pt 12):2601-5. doi: 10.1099/vir.0.046284-0. Epub 2012 Sep 5.

PMID:
22956738
17.

Activation of type III interferon genes by pathogenic bacteria in infected epithelial cells and mouse placenta.

Bierne H, Travier L, Mahlakõiv T, Tailleux L, Subtil A, Lebreton A, Paliwal A, Gicquel B, Staeheli P, Lecuit M, Cossart P.

PLoS One. 2012;7(6):e39080. doi: 10.1371/journal.pone.0039080. Epub 2012 Jun 14.

18.

IFN-lambda determines the intestinal epithelial antiviral host defense.

Pott J, Mahlakõiv T, Mordstein M, Duerr CU, Michiels T, Stockinger S, Staeheli P, Hornef MW.

Proc Natl Acad Sci U S A. 2011 May 10;108(19):7944-9. doi: 10.1073/pnas.1100552108. Epub 2011 Apr 25.

19.

High prevalence of both humoral and cellular immunity to Zaire ebolavirus among rural populations in Gabon.

Becquart P, Wauquier N, Mahlakõiv T, Nkoghe D, Padilla C, Souris M, Ollomo B, Gonzalez JP, De Lamballerie X, Kazanji M, Leroy EM.

PLoS One. 2010 Feb 9;5(2):e9126. doi: 10.1371/journal.pone.0009126. Erratum in: PLoS One. 2010;5(2) doi: 10.1371/annotation/9bc62f9e-8386-4e9b-951c-1eeba930a41c.

20.

Acetylation of H3 K56 is required for RNA polymerase II transcript elongation through heterochromatin in yeast.

Värv S, Kristjuhan K, Peil K, Lõoke M, Mahlakõiv T, Paapsi K, Kristjuhan A.

Mol Cell Biol. 2010 Mar;30(6):1467-77. doi: 10.1128/MCB.01151-09. Epub 2010 Jan 11.

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