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Items: 1 to 50 of 100

1.

New concepts in C. difficile management.

Mahida YR.

Br Med Bull. 2019 Sep 19;131(1):109-118. doi: 10.1093/bmb/ldz029.

PMID:
31583398
2.

Slow cycling intestinal stem cell and Paneth cell responses to Trichinella spiralis infection.

Javkar T, Hughes KR, Sablitzky F, Behnke JM, Mahida YR.

Parasitol Int. 2020 Feb;74:101923. doi: 10.1016/j.parint.2019.05.001. Epub 2019 May 2.

PMID:
31054916
3.

Determination of Histone 2B-Green Fluorescent Protein (GFP) Retention in Intestinal Stem Cells.

Hughes KR, Mahida YR.

Methods Mol Biol. 2018;1686:79-89. doi: 10.1007/978-1-4939-7371-2_6.

PMID:
29030814
4.

Pathogenesis of Clostridium difficile Infection and Its Potential Role in Inflammatory Bowel Disease.

Monaghan TM, Cockayne A, Mahida YR.

Inflamm Bowel Dis. 2015 Aug;21(8):1957-66. doi: 10.1097/MIB.0000000000000461. Review.

PMID:
26199993
5.
6.

Circulating antibody and memory B-Cell responses to C. difficile toxins A and B in patients with C. difficile-associated diarrhoea, inflammatory bowel disease and cystic fibrosis.

Monaghan TM, Robins A, Knox A, Sewell HF, Mahida YR.

PLoS One. 2013 Sep 10;8(9):e74452. doi: 10.1371/journal.pone.0074452. eCollection 2013.

7.

Heterogeneity in histone 2B-green fluorescent protein-retaining putative small intestinal stem cells at cell position 4 and their absence in the colon.

Hughes KR, Gândara RM, Javkar T, Sablitzky F, Hock H, Potten CS, Mahida YR.

Am J Physiol Gastrointest Liver Physiol. 2012 Dec 1;303(11):G1188-201. doi: 10.1152/ajpgi.00080.2012. Epub 2012 Sep 20.

8.

Regional differences in stem and transit cell proliferation and apoptosis in the terminal ileum and colon of mice after 12 Gy.

Gândara RM, Mahida YR, Potten CS.

Int J Radiat Oncol Biol Phys. 2012 Mar 1;82(3):e521-8. doi: 10.1016/j.ijrobp.2011.07.015. Epub 2011 Dec 21.

PMID:
22196132
9.

Differential binding and internalization of Clostridium difficile toxin A by human peripheral blood monocytes, neutrophils and lymphocytes.

Modi N, Gulati N, Solomon K, Monaghan T, Robins A, Sewell HF, Mahida YR.

Scand J Immunol. 2011 Sep;74(3):264-271. doi: 10.1111/j.1365-3083.2011.02578.x.

10.

Primary human colonic myofibroblasts are resistant to Clostridium difficile toxin A-induced, but not toxin B-induced, cell death.

Mullan N, Hughes KR, Mahida YR.

Infect Immun. 2011 Apr;79(4):1623-30. doi: 10.1128/IAI.00686-10. Epub 2011 Jan 18.

11.
12.

The stem cells of small intestinal crypts: where are they?

Potten CS, Gandara R, Mahida YR, Loeffler M, Wright NA.

Cell Prolif. 2009 Dec;42(6):731-50. doi: 10.1111/j.1365-2184.2009.00642.x. Epub 2009 Sep 28.

PMID:
19788585
13.

Epithelial stem cell-related alterations in Trichinella spiralis-infected small intestine.

Walsh R, Seth R, Behnke J, Potten CS, Mahida YR.

Cell Prolif. 2009 Jun;42(3):394-403. doi: 10.1111/j.1365-2184.2009.00605.x. Epub 2009 Apr 9.

14.

Recent advances in Clostridium difficile-associated disease.

Monaghan T, Boswell T, Mahida YR.

Postgrad Med J. 2009 Mar;85(1001):152-62. doi: 10.1136/gut.2007.128157. Review.

PMID:
19351643
15.

Characterization of putative stem cells in isolated human colonic crypt epithelial cells and their interactions with myofibroblasts.

Samuel S, Walsh R, Webb J, Robins A, Potten C, Mahida YR.

Am J Physiol Cell Physiol. 2009 Feb;296(2):C296-305. doi: 10.1152/ajpcell.00383.2008. Epub 2008 Dec 10.

16.

Do non-immune cells have a role in IBD?

Mahida YR, Moran GW.

Inflamm Bowel Dis. 2008 Oct;14 Suppl 2:S123-4. doi: 10.1002/ibd.20680. No abstract available. Erratum in: Inflamm Bowel Dis. 2009 Sep;15(9):1438-47.

PMID:
18816764
17.

Essential role of toxin A in C. difficile 027 and reference strain supernatant-mediated disruption of Caco-2 intestinal epithelial barrier function.

Sutton PA, Li S, Webb J, Solomon K, Brazier J, Mahida YR.

Clin Exp Immunol. 2008 Sep;153(3):439-47. doi: 10.1111/j.1365-2249.2008.03690.x. Epub 2008 May 26.

18.

Impaired luminal processing of human defensin-5 in Crohn's disease: persistence in a complex with chymotrypsinogen and trypsin.

Elphick D, Liddell S, Mahida YR.

Am J Pathol. 2008 Mar;172(3):702-13. doi: 10.2353/ajpath.2008.070755. Epub 2008 Feb 7.

19.

Recent advances in Clostridium difficile-associated disease.

Monaghan T, Boswell T, Mahida YR.

Gut. 2008 Jun;57(6):850-60. doi: 10.1136/gut.2007.128157. Epub 2008 Feb 5. Review.

PMID:
18252748
20.

Alteration in human defensin-5 expression following gastric bypass surgery.

Sundbom M, Elphick DA, Mahida YR, Cunliffe RN, Midtvedt T, Engstrand L, Rubio C, Axelsson LG.

J Clin Pathol. 2007 Sep;60(9):1029-34. Epub 2007 Apr 5.

21.

Effects of Trichinella spiralis infection on intestinal pathology in mice lacking interleukin-4 (IL-4) or intestinal trefoil factor (ITF/TFF3).

Dehlawi MS, Mahida YR, Hughes K, Wakelin D.

Parasitol Int. 2006 Sep;55(3):207-11. Epub 2006 Jun 30.

PMID:
16814598
22.

Paneth cells: their role in innate immunity and inflammatory disease.

Elphick DA, Mahida YR.

Gut. 2005 Dec;54(12):1802-9. Review. No abstract available.

23.
24.

Monocytes are highly sensitive to clostridium difficile toxin A-induced apoptotic and nonapoptotic cell death.

Solomon K, Webb J, Ali N, Robins RA, Mahida YR.

Infect Immun. 2005 Mar;73(3):1625-34.

25.

Defensins and mucosal protection.

Mahida YR, Cunliffe RN.

Novartis Found Symp. 2004;263:71-7; discussion 77-84, 211-8. Review.

PMID:
15669635
26.

Colonic IgA producing cells and macrophages are reduced in recurrent and non-recurrent Clostridium difficile associated diarrhoea.

Johal SS, Lambert CP, Hammond J, James PD, Borriello SP, Mahida YR.

J Clin Pathol. 2004 Sep;57(9):973-9.

27.

Host-bacterial interactions in inflammatory bowel disease.

Mahida YR, Rolfe VE.

Clin Sci (Lond). 2004 Oct;107(4):331-41. Review.

PMID:
15212627
28.

Differential effects of varying concentrations of clostridium difficile toxin A on epithelial barrier function and expression of cytokines.

Johal SS, Solomon K, Dodson S, Borriello SP, Mahida YR.

J Infect Dis. 2004 Jun 1;189(11):2110-9. Epub 2004 Apr 30.

PMID:
15143480
29.

Microbial-gut interactions in health and disease. Epithelial cell responses.

Mahida YR.

Best Pract Res Clin Gastroenterol. 2004 Apr;18(2):241-53. Review.

PMID:
15123067
30.
31.

A pilot study to investigate the use of oxpentifylline (pentoxifylline) and thalidomide in portal hypertension secondary to alcoholic cirrhosis.

Austin AS, Mahida YR, Clarke D, Ryder SD, Freeman JG.

Aliment Pharmacol Ther. 2004 Jan 1;19(1):79-88.

32.

Expression and regulation of antimicrobial peptides in the gastrointestinal tract.

Cunliffe RN, Mahida YR.

J Leukoc Biol. 2004 Jan;75(1):49-58. Epub 2003 Oct 2. Review.

PMID:
14525966
33.

Host-parasite interactions in rodent nematode infections.

Mahida YR.

J Helminthol. 2003 Jun;77(2):125-31. Review.

PMID:
12756066
35.

Selective reduction of intestinal trefoil factor in untreated coeliac disease.

Ciacci C, Di Vizio D, Seth R, Insabato G, Mazzacca G, Podolsky DK, Mahida YR.

Clin Exp Immunol. 2002 Dec;130(3):526-31.

36.

Expression of antimicrobial neutrophil defensins in epithelial cells of active inflammatory bowel disease mucosa.

Cunliffe RN, Kamal M, Rose FR, James PD, Mahida YR.

J Clin Pathol. 2002 Apr;55(4):298-304.

37.

Toxicity of mycophenolate mofetil in patients with inflammatory bowel disease.

Skelly MM, Logan RF, Jenkins D, Mahida YR, Hawkey CJ.

Inflamm Bowel Dis. 2002 Mar;8(2):93-7.

PMID:
11854606
38.

Differential expression of TGF-beta isoforms by normal and inflammatory bowel disease intestinal myofibroblasts.

McKaig BC, Hughes K, Tighe PJ, Mahida YR.

Am J Physiol Cell Physiol. 2002 Jan;282(1):C172-82.

39.

Mucosal T cells regulate Paneth and intermediate cell numbers in the small intestine of T. spiralis-infected mice.

Kamal M, Wakelin D, Ouellette AJ, Smith A, Podolsky DK, Mahida YR.

Clin Exp Immunol. 2001 Oct;126(1):117-25.

40.

Nocardia asteroides lung abscess in acute ulcerative colitis treated with cyclosporine.

Stack WA, Richardson PD, Logan RP, Mahida YR, Hawkey CJ.

Am J Gastroenterol. 2001 Jul;96(7):2255-6.

PMID:
11467663
41.

NF-kappa B may determine whether epithelial cell--microbial interactions in the intestine are hostile or friendly.

Mahida YR, Johal S.

Clin Exp Immunol. 2001 Mar;123(3):347-9. No abstract available.

43.

Cyclooxygenase (COX) 1 and 2 in normal, inflamed, and ulcerated human gastric mucosa.

Jackson LM, Wu KC, Mahida YR, Jenkins D, Hawkey CJ.

Gut. 2000 Dec;47(6):762-70.

44.

Antimicrobial peptides in innate intestinal host defence.

Cunliffe RN, Mahida YR.

Gut. 2000 Jul;47(1):16-7. Review. No abstract available.

45.

The key role of macrophages in the immunopathogenesis of inflammatory bowel disease.

Mahida YR.

Inflamm Bowel Dis. 2000 Feb;6(1):21-33. Review.

PMID:
10701146
46.

Bacteroides fragilis enterotoxin induces the expression of IL-8 and transforming growth factor-beta (TGF-beta) by human colonic epithelial cells.

Sanfilippo L, Li CK, Seth R, Balwin TJ, Menozzi MG, Mahida YR.

Clin Exp Immunol. 2000 Mar;119(3):456-63.

47.

Human colonic subepithelial myofibroblasts modulate transepithelial resistance and secretory response.

Beltinger J, McKaig BC, Makh S, Stack WA, Hawkey CJ, Mahida YR.

Am J Physiol. 1999 Aug;277(2):C271-9. doi: 10.1152/ajpcell.1999.277.2.C271.

PMID:
10444403
48.

Investigation of the expression of IL-1beta converting enzyme and apoptosis in normal and inflammatory bowel disease (IBD) mucosal macrophages.

McAlindon ME, Galvin A, McKaig B, Gray T, Sewell HF, Mahida YR.

Clin Exp Immunol. 1999 May;116(2):251-7.

49.

Normal human colonic subepithelial myofibroblasts enhance epithelial migration (restitution) via TGF-beta3.

McKaig BC, Makh SS, Hawkey CJ, Podolsky DK, Mahida YR.

Am J Physiol. 1999 May;276(5):G1087-93. doi: 10.1152/ajpgi.1999.276.5.G1087.

PMID:
10329998
50.

Clostridium difficile-associated diarrhoea.

Wight N, Curtis H, Hyde J, Borriello SP, Mahida YR.

Postgrad Med J. 1998 Nov;74(877):677-8.

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