Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 60

1.

Isotope Tracing of Human Clear Cell Renal Cell Carcinomas Demonstrates Suppressed Glucose Oxidation In Vivo.

Courtney KD, Bezwada D, Mashimo T, Pichumani K, Vemireddy V, Funk AM, Wimberly J, McNeil SS, Kapur P, Lotan Y, Margulis V, Cadeddu JA, Pedrosa I, DeBerardinis RJ, Malloy CR, Bachoo RM, Maher EA.

Cell Metab. 2018 Aug 21. pii: S1550-4131(18)30463-7. doi: 10.1016/j.cmet.2018.07.020. [Epub ahead of print]

PMID:
30146487
2.

Measurement of 13 C turnover into glutamate and glutamine pools in brain tumor patients.

Pichumani K, Mashimo T, Vemireddy V, Ijare OB, Mickey BE, Malloy CR, Marin-Valencia I, Baskin DS, Bachoo RM, Maher EA.

FEBS Lett. 2017 Nov;591(21):3548-3554. doi: 10.1002/1873-3468.12867. Epub 2017 Oct 27.

PMID:
28963851
3.

Echo-planar spectroscopic imaging with dual-readout alternated gradients (DRAG-EPSI) at 7 T: Application for 2-hydroxyglutarate imaging in glioma patients.

An Z, Tiwari V, Ganji SK, Baxter J, Levy M, Pinho MC, Pan E, Maher EA, Patel TR, Mickey BE, Choi C.

Magn Reson Med. 2018 Apr;79(4):1851-1861. doi: 10.1002/mrm.26884. Epub 2017 Aug 22.

PMID:
28833542
4.

Measurement of glycine in healthy and tumorous brain by triple-refocusing MRS at 3 T in vivo.

Tiwari V, An Z, Ganji SK, Baxter J, Patel TR, Pan E, Mickey BE, Maher EA, Pinho MC, Choi C.

NMR Biomed. 2017 Sep;30(9). doi: 10.1002/nbm.3747. Epub 2017 May 26.

5.

Rapid progression to glioblastoma in a subset of IDH-mutated astrocytomas: a genome-wide analysis.

Richardson TE, Snuderl M, Serrano J, Karajannis MA, Heguy A, Oliver D, Raisanen JM, Maher EA, Pan E, Barnett S, Cai C, Habib AA, Bachoo RM, Hatanpaa KJ.

J Neurooncol. 2017 May;133(1):183-192. doi: 10.1007/s11060-017-2431-y. Epub 2017 Apr 18.

PMID:
28421459
6.

Noninvasive assessment of isocitrate dehydrogenase mutation status in cerebral gliomas by magnetic resonance spectroscopy in a clinical setting.

Tietze A, Choi C, Mickey B, Maher EA, Parm Ulhøi B, Sangill R, Lassen-Ramshad Y, Lukacova S, Østergaard L, von Oettingen G.

J Neurosurg. 2018 Feb;128(2):391-398. doi: 10.3171/2016.10.JNS161793. Epub 2017 Mar 3.

PMID:
28298040
7.

Prospective Longitudinal Analysis of 2-Hydroxyglutarate Magnetic Resonance Spectroscopy Identifies Broad Clinical Utility for the Management of Patients With IDH-Mutant Glioma.

Choi C, Raisanen JM, Ganji SK, Zhang S, McNeil SS, An Z, Madan A, Hatanpaa KJ, Vemireddy V, Sheppard CA, Oliver D, Hulsey KM, Tiwari V, Mashimo T, Battiste J, Barnett S, Madden CJ, Patel TR, Pan E, Malloy CR, Mickey BE, Bachoo RM, Maher EA.

J Clin Oncol. 2016 Nov 20;34(33):4030-4039. doi: 10.1200/JCO.2016.67.1222. Epub 2016 Oct 31.

8.

Oncogenes Activate an Autonomous Transcriptional Regulatory Circuit That Drives Glioblastoma.

Singh DK, Kollipara RK, Vemireddy V, Yang XL, Sun Y, Regmi N, Klingler S, Hatanpaa KJ, Raisanen J, Cho SK, Sirasanagandla S, Nannepaga S, Piccirillo S, Mashimo T, Wang S, Humphries CG, Mickey B, Maher EA, Zheng H, Kim RS, Kittler R, Bachoo RM.

Cell Rep. 2017 Jan 24;18(4):961-976. doi: 10.1016/j.celrep.2016.12.064.

9.

Selection of antigenically advanced variants of seasonal influenza viruses.

Li C, Hatta M, Burke DF, Ping J, Zhang Y, Ozawa M, Taft AS, Das SC, Hanson AP, Song J, Imai M, Wilker PR, Watanabe T, Watanabe S, Ito M, Iwatsuki-Horimoto K, Russell CA, James SL, Skepner E, Maher EA, Neumann G, Klimov AI, Kelso A, McCauley J, Wang D, Shu Y, Odagiri T, Tashiro M, Xu X, Wentworth DE, Katz JM, Cox NJ, Smith DJ, Kawaoka Y.

Nat Microbiol. 2016 May 23;1(6):16058. doi: 10.1038/nmicrobiol.2016.58.

10.

Detection of 2-hydroxyglutarate in brain tumors by triple-refocusing MR spectroscopy at 3T in vivo.

An Z, Ganji SK, Tiwari V, Pinho MC, Patel T, Barnett S, Pan E, Mickey BE, Maher EA, Choi C.

Magn Reson Med. 2017 Jul;78(1):40-48. doi: 10.1002/mrm.26347. Epub 2016 Jul 25.

11.

Hepatic gluconeogenesis influences (13)C enrichment in lactate in human brain tumors during metabolism of [1,2-(13)C]acetate.

Pichumani K, Mashimo T, Vemireddy V, Kovacs Z, Ratnakar J, Mickey B, Malloy CR, DeBerardinis RJ, Bachoo RM, Maher EA.

Neurochem Int. 2016 Jul;97:133-6. doi: 10.1016/j.neuint.2016.03.015. Epub 2016 Mar 26.

12.

In vivo detection of 2-hydroxyglutarate in brain tumors by optimized point-resolved spectroscopy (PRESS) at 7T.

Ganji SK, An Z, Tiwari V, McNeil S, Pinho MC, Pan E, Mickey BE, Maher EA, Choi C.

Magn Reson Med. 2017 Mar;77(3):936-944. doi: 10.1002/mrm.26190. Epub 2016 Mar 16.

13.

Development of high-yield influenza A virus vaccine viruses.

Ping J, Lopes TJ, Nidom CA, Ghedin E, Macken CA, Fitch A, Imai M, Maher EA, Neumann G, Kawaoka Y.

Nat Commun. 2015 Sep 2;6:8148. doi: 10.1038/ncomms9148.

14.

Identification of mammalian-adapting mutations in the polymerase complex of an avian H5N1 influenza virus.

Taft AS, Ozawa M, Fitch A, Depasse JV, Halfmann PJ, Hill-Batorski L, Hatta M, Friedrich TC, Lopes TJ, Maher EA, Ghedin E, Macken CA, Neumann G, Kawaoka Y.

Nat Commun. 2015 Jun 17;6:7491. doi: 10.1038/ncomms8491.

15.

Conditions for (13)C NMR detection of 2-hydroxyglutarate in tissue extracts from isocitrate dehydrogenase-mutated gliomas.

Pichumani K, Mashimo T, Baek HM, Ratnakar J, Mickey B, DeBerardinis RJ, Maher EA, Bachoo RM, Malloy CR, Kovacs Z.

Anal Biochem. 2015 Jul 15;481:4-6. doi: 10.1016/j.ab.2015.04.017. Epub 2015 Apr 20.

16.

In vivo (1)H MRSI of glycine in brain tumors at 3T.

Ganji SK, Maher EA, Choi C.

Magn Reson Med. 2016 Jan;75(1):52-62. doi: 10.1002/mrm.25588. Epub 2015 Feb 4.

17.

Acetate is a bioenergetic substrate for human glioblastoma and brain metastases.

Mashimo T, Pichumani K, Vemireddy V, Hatanpaa KJ, Singh DK, Sirasanagandla S, Nannepaga S, Piccirillo SG, Kovacs Z, Foong C, Huang Z, Barnett S, Mickey BE, DeBerardinis RJ, Tu BP, Maher EA, Bachoo RM.

Cell. 2014 Dec 18;159(7):1603-14. doi: 10.1016/j.cell.2014.11.025.

18.

¹H MRS characterization of neurochemical profiles in orthotopic mouse models of human brain tumors.

Hulsey KM, Mashimo T, Banerjee A, Soesbe TC, Spence JS, Vemireddy V, Maher EA, Bachoo RM, Choi C.

NMR Biomed. 2015 Jan;28(1):108-15. doi: 10.1002/nbm.3231. Epub 2014 Nov 13.

PMID:
25394324
19.

Pandemic potential of avian influenza A (H7N9) viruses.

Watanabe T, Watanabe S, Maher EA, Neumann G, Kawaoka Y.

Trends Microbiol. 2014 Nov;22(11):623-31. doi: 10.1016/j.tim.2014.08.008. Epub 2014 Sep 25. Review.

20.

Circulating avian influenza viruses closely related to the 1918 virus have pandemic potential.

Watanabe T, Zhong G, Russell CA, Nakajima N, Hatta M, Hanson A, McBride R, Burke DF, Takahashi K, Fukuyama S, Tomita Y, Maher EA, Watanabe S, Imai M, Neumann G, Hasegawa H, Paulson JC, Smith DJ, Kawaoka Y.

Cell Host Microbe. 2014 Jun 11;15(6):692-705. doi: 10.1016/j.chom.2014.05.006.

21.

In vivo chemical exchange saturation transfer imaging allows early detection of a therapeutic response in glioblastoma.

Sagiyama K, Mashimo T, Togao O, Vemireddy V, Hatanpaa KJ, Maher EA, Mickey BE, Pan E, Sherry AD, Bachoo RM, Takahashi M.

Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4542-7. doi: 10.1073/pnas.1323855111. Epub 2014 Mar 10.

22.

High expression of the stem cell marker nestin is an adverse prognostic factor in WHO grade II-III astrocytomas and oligoastrocytomas.

Hatanpaa KJ, Hu T, Vemireddy V, Foong C, Raisanen JM, Oliver D, Hiemenz MC, Burns DK, White CL 3rd, Whitworth LA, Mickey B, Stegner M, Habib AA, Fink K, Maher EA, Bachoo RM.

J Neurooncol. 2014 Mar;117(1):183-189. doi: 10.1007/s11060-014-1376-7. Epub 2014 Feb 12.

23.

In vivo detection of citrate in brain tumors by 1H magnetic resonance spectroscopy at 3T.

Choi C, Ganji SK, Madan A, Hulsey KM, An Z, Zhang S, Pinho MC, DeBerardinis RJ, Bachoo RM, Maher EA.

Magn Reson Med. 2014 Aug;72(2):316-23. doi: 10.1002/mrm.24946. Epub 2013 Oct 1.

24.

Characterization of H7N9 influenza A viruses isolated from humans.

Watanabe T, Kiso M, Fukuyama S, Nakajima N, Imai M, Yamada S, Murakami S, Yamayoshi S, Iwatsuki-Horimoto K, Sakoda Y, Takashita E, McBride R, Noda T, Hatta M, Imai H, Zhao D, Kishida N, Shirakura M, de Vries RP, Shichinohe S, Okamatsu M, Tamura T, Tomita Y, Fujimoto N, Goto K, Katsura H, Kawakami E, Ishikawa I, Watanabe S, Ito M, Sakai-Tagawa Y, Sugita Y, Uraki R, Yamaji R, Eisfeld AJ, Zhong G, Fan S, Ping J, Maher EA, Hanson A, Uchida Y, Saito T, Ozawa M, Neumann G, Kida H, Odagiri T, Paulson JC, Hasegawa H, Tashiro M, Kawaoka Y.

Nature. 2013 Sep 26;501(7468):551-5. doi: 10.1038/nature12392. Epub 2013 Jul 10.

25.

Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets.

Imai M, Watanabe T, Hatta M, Das SC, Ozawa M, Shinya K, Zhong G, Hanson A, Katsura H, Watanabe S, Li C, Kawakami E, Yamada S, Kiso M, Suzuki Y, Maher EA, Neumann G, Kawaoka Y.

Nature. 2012 May 2;486(7403):420-8. doi: 10.1038/nature10831.

26.

Analysis of tumor metabolism reveals mitochondrial glucose oxidation in genetically diverse human glioblastomas in the mouse brain in vivo.

Marin-Valencia I, Yang C, Mashimo T, Cho S, Baek H, Yang XL, Rajagopalan KN, Maddie M, Vemireddy V, Zhao Z, Cai L, Good L, Tu BP, Hatanpaa KJ, Mickey BE, Matés JM, Pascual JM, Maher EA, Malloy CR, Deberardinis RJ, Bachoo RM.

Cell Metab. 2012 Jun 6;15(6):827-37. doi: 10.1016/j.cmet.2012.05.001. Erratum in: Cell Metab. 2012 Nov 7;16(5):686.

27.

Metabolism of [U-13 C]glucose in human brain tumors in vivo.

Maher EA, Marin-Valencia I, Bachoo RM, Mashimo T, Raisanen J, Hatanpaa KJ, Jindal A, Jeffrey FM, Choi C, Madden C, Mathews D, Pascual JM, Mickey BE, Malloy CR, DeBerardinis RJ.

NMR Biomed. 2012 Nov;25(11):1234-44. doi: 10.1002/nbm.2794. Epub 2012 Mar 15.

28.

Glucose metabolism via the pentose phosphate pathway, glycolysis and Krebs cycle in an orthotopic mouse model of human brain tumors.

Marin-Valencia I, Cho SK, Rakheja D, Hatanpaa KJ, Kapur P, Mashimo T, Jindal A, Vemireddy V, Good LB, Raisanen J, Sun X, Mickey B, Choi C, Takahashi M, Togao O, Pascual JM, Deberardinis RJ, Maher EA, Malloy CR, Bachoo RM.

NMR Biomed. 2012 Oct;25(10):1177-86. doi: 10.1002/nbm.2787. Epub 2012 Mar 1.

29.

Compressive sensing could accelerate 1H MR metabolic imaging in the clinic.

Geethanath S, Baek HM, Ganji SK, Ding Y, Maher EA, Sims RD, Choi C, Lewis MA, Kodibagkar VD.

Radiology. 2012 Mar;262(3):985-94. doi: 10.1148/radiol.11111098.

30.

2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas.

Choi C, Ganji SK, DeBerardinis RJ, Hatanpaa KJ, Rakheja D, Kovacs Z, Yang XL, Mashimo T, Raisanen JM, Marin-Valencia I, Pascual JM, Madden CJ, Mickey BE, Malloy CR, Bachoo RM, Maher EA.

Nat Med. 2012 Jan 26;18(4):624-9. doi: 10.1038/nm.2682.

31.

Replication-incompetent influenza A viruses that stably express a foreign gene.

Ozawa M, Victor ST, Taft AS, Yamada S, Li C, Hatta M, Das SC, Takashita E, Kakugawa S, Maher EA, Neumann G, Kawaoka Y.

J Gen Virol. 2011 Dec;92(Pt 12):2879-88. doi: 10.1099/vir.0.037648-0. Epub 2011 Aug 31.

32.

T2 measurement of J-coupled metabolites in the human brain at 3T.

Ganji SK, Banerjee A, Patel AM, Zhao YD, Dimitrov IE, Browning JD, Brown ES, Maher EA, Choi C.

NMR Biomed. 2012 Apr;25(4):523-9. doi: 10.1002/nbm.1767. Epub 2011 Aug 15.

33.

Measurement of glycine in the human brain in vivo by 1H-MRS at 3 T: application in brain tumors.

Choi C, Ganji SK, DeBerardinis RJ, Dimitrov IE, Pascual JM, Bachoo R, Mickey BE, Malloy CR, Maher EA.

Magn Reson Med. 2011 Sep;66(3):609-18. doi: 10.1002/mrm.22857. Epub 2011 Mar 9.

34.

Dedifferentiated adenoid cystic carcinoma of the lacrimal gland.

Panarelli JF, Zoumalan CI, Mukkamala K, Maher EA, Iacob C, Della Rocca DA.

Ophthalmic Plast Reconstr Surg. 2011 Sep-Oct;27(5):e119-21. doi: 10.1097/IOP.0b013e318201cb90.

PMID:
21283029
35.

Improvement of resolution for brain coupled metabolites by optimized (1)H MRS at 7T.

Choi C, Dimitrov IE, Douglas D, Patel A, Kaiser LG, Amezcua CA, Maher EA.

NMR Biomed. 2010 Nov;23(9):1044-52. doi: 10.1002/nbm.1529.

PMID:
20963800
36.

Balloon canaliculoplasty for acquired canalicular stenosis.

Zoumalan CI, Maher EA, Lelli GJ Jr, Lisman RD.

Ophthalmic Plast Reconstr Surg. 2010 Nov-Dec;26(6):459-61. doi: 10.1097/IOP.0b013e3181eea303.

PMID:
20871460
37.

The telomerase antagonist, imetelstat, efficiently targets glioblastoma tumor-initiating cells leading to decreased proliferation and tumor growth.

Marian CO, Cho SK, McEllin BM, Maher EA, Hatanpaa KJ, Madden CJ, Mickey BE, Wright WE, Shay JW, Bachoo RM.

Clin Cancer Res. 2010 Jan 1;16(1):154-63. doi: 10.1158/1078-0432.CCR-09-2850.

38.

Brain metastasis: opportunities in basic and translational research.

Maher EA, Mietz J, Arteaga CL, DePinho RA, Mohla S.

Cancer Res. 2009 Aug 1;69(15):6015-20. doi: 10.1158/0008-5472.CAN-08-4347. Epub 2009 Jul 28. No abstract available.

39.

Proboscis lateralis.

Lelli GJ Jr, Maher EA, Milite JP, Dyleski R.

Ophthalmic Plast Reconstr Surg. 2008 Nov-Dec;24(6):499-501. doi: 10.1097/IOP.0b013e31818b6e57.

PMID:
19033859
40.

Marked genomic differences characterize primary and secondary glioblastoma subtypes and identify two distinct molecular and clinical secondary glioblastoma entities.

Maher EA, Brennan C, Wen PY, Durso L, Ligon KL, Richardson A, Khatry D, Feng B, Sinha R, Louis DN, Quackenbush J, Black PM, Chin L, DePinho RA.

Cancer Res. 2006 Dec 1;66(23):11502-13. Epub 2006 Nov 17.

41.

Phase I/II study of imatinib mesylate for recurrent malignant gliomas: North American Brain Tumor Consortium Study 99-08.

Wen PY, Yung WK, Lamborn KR, Dahia PL, Wang Y, Peng B, Abrey LE, Raizer J, Cloughesy TF, Fink K, Gilbert M, Chang S, Junck L, Schiff D, Lieberman F, Fine HA, Mehta M, Robins HI, DeAngelis LM, Groves MD, Puduvalli VK, Levin V, Conrad C, Maher EA, Aldape K, Hayes M, Letvak L, Egorin MJ, Capdeville R, Kaplan R, Murgo AJ, Stiles C, Prados MD.

Clin Cancer Res. 2006 Aug 15;12(16):4899-907.

42.

A rapid and sensitive enzymatic method for epidermal growth factor receptor mutation screening.

Jänne PA, Borras AM, Kuang Y, Rogers AM, Joshi VA, Liyanage H, Lindeman N, Lee JC, Halmos B, Maher EA, Distel RJ, Meyerson M, Johnson BE.

Clin Cancer Res. 2006 Feb 1;12(3 Pt 1):751-8.

43.

A novel yeast two-hybrid approach to identify CDPK substrates: characterization of the interaction between AtCPK11 and AtDi19, a nuclear zinc finger protein.

Rodriguez Milla MA, Uno Y, Chang IF, Townsend J, Maher EA, Quilici D, Cushman JC.

FEBS Lett. 2006 Feb 6;580(3):904-11. Epub 2006 Jan 18.

44.

Mouse Models of Human Cancers Consortium Workshop on Nervous System Tumors.

Gutmann DH, Maher EA, Van Dyke T.

Cancer Res. 2006 Jan 1;66(1):10-3.

45.

Hyperinsulinemic hypoglycemia in Beckwith-Wiedemann syndrome due to defects in the function of pancreatic beta-cell adenosine triphosphate-sensitive potassium channels.

Hussain K, Cosgrove KE, Shepherd RM, Luharia A, Smith VV, Kassem S, Gregory JW, Sivaprasadarao A, Christesen HT, Jacobsen BB, Brusgaard K, Glaser B, Maher EA, Lindley KJ, Hindmarsh P, Dattani M, Dunne MJ.

J Clin Endocrinol Metab. 2005 Jul;90(7):4376-82. Epub 2005 Apr 5.

PMID:
15811927
46.

Molecular diversity of astrocytes with implications for neurological disorders.

Bachoo RM, Kim RS, Ligon KL, Maher EA, Brennan C, Billings N, Chan S, Li C, Rowitch DH, Wong WH, DePinho RA.

Proc Natl Acad Sci U S A. 2004 Jun 1;101(22):8384-9. Epub 2004 May 21.

47.

Phase II trial of thalidomide and carmustine for patients with recurrent high-grade gliomas.

Fine HA, Wen PY, Maher EA, Viscosi E, Batchelor T, Lakhani N, Figg WD, Purow BW, Borkowf CB.

J Clin Oncol. 2003 Jun 15;21(12):2299-304.

PMID:
12805330
48.

Endoscopic and transconjunctival orbital decompression for thyroid-related orbital apex compression.

Schaefer SD, Soliemanzadeh P, Della Rocca DA, Yoo GP, Maher EA, Milite JP, Della Rocca RC.

Laryngoscope. 2003 Mar;113(3):508-13.

PMID:
12616205
49.

Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis.

Bachoo RM, Maher EA, Ligon KL, Sharpless NE, Chan SS, You MJ, Tang Y, DeFrances J, Stover E, Weissleder R, Rowitch DH, Louis DN, DePinho RA.

Cancer Cell. 2002 Apr;1(3):269-77.

50.

Malignant glioma: genetics and biology of a grave matter.

Maher EA, Furnari FB, Bachoo RM, Rowitch DH, Louis DN, Cavenee WK, DePinho RA.

Genes Dev. 2001 Jun 1;15(11):1311-33. Review. No abstract available.

Supplemental Content

Loading ...
Support Center