Sort by
Items per page

Send to

Choose Destination

Search results

Items: 29


Disruption of TCF4 regulatory networks leads to abnormal cortical development and mental disabilities.

Li H, Zhu Y, Morozov YM, Chen X, Page SC, Rannals MD, Maher BJ, Rakic P.

Mol Psychiatry. 2019 Aug;24(8):1235-1246. doi: 10.1038/s41380-019-0353-0. Epub 2019 Jan 31.


Cortistatin-expressing interneurons require TrkB signaling to suppress neural hyper-excitability.

Hill JL, Jimenez DV, Mai Y, Ren M, Hallock HL, Maynard KR, Chen HY, Hardy NF, Schloesser RJ, Maher BJ, Yang F, Martinowich K.

Brain Struct Funct. 2019 Jan;224(1):471-483. doi: 10.1007/s00429-018-1783-1. Epub 2018 Oct 30.


Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis.

Jaffe AE, Straub RE, Shin JH, Tao R, Gao Y, Collado-Torres L, Kam-Thong T, Xi HS, Quan J, Chen Q, Colantuoni C, Ulrich WS, Maher BJ, Deep-Soboslay A; BrainSeq Consortium, Cross AJ, Brandon NJ, Leek JT, Hyde TM, Kleinman JE, Weinberger DR.

Nat Neurosci. 2018 Aug;21(8):1117-1125. doi: 10.1038/s41593-018-0197-y. Epub 2018 Jul 26.


The Intellectual Disability and Schizophrenia Associated Transcription Factor TCF4 Is Regulated by Neuronal Activity and Protein Kinase A.

Sepp M, Vihma H, Nurm K, Urb M, Page SC, Roots K, Hark A, Maher BJ, Pruunsild P, Timmusk T.

J Neurosci. 2017 Oct 25;37(43):10516-10527. doi: 10.1523/JNEUROSCI.1151-17.2017. Epub 2017 Sep 26.


The schizophrenia- and autism-associated gene, transcription factor 4 regulates the columnar distribution of layer 2/3 prefrontal pyramidal neurons in an activity-dependent manner.

Page SC, Hamersky GR, Gallo RA, Rannals MD, Calcaterra NE, Campbell MN, Mayfield B, Briley A, Phan BN, Jaffe AE, Maher BJ.

Mol Psychiatry. 2018 Feb;23(2):304-315. doi: 10.1038/mp.2017.37. Epub 2017 Mar 14.


Molecular Mechanisms of Transcription Factor 4 in Pitt Hopkins Syndrome.

Rannals MD, Maher BJ.

Curr Genet Med Rep. 2017 Mar;5(1):1-7. doi: 10.1007/s40142-017-0110-0. Epub 2017 Feb 11.


Using Induced Pluripotent Stem Cells to Investigate Complex Genetic Psychiatric Disorders.

Temme SJ, Maher BJ, Christian KM.

Curr Behav Neurosci Rep. 2016 Dec;3(4):275-284. doi: 10.1007/s40473-016-0100-7. Epub 2016 Oct 14.


Neurodevelopmental models of transcription factor 4 deficiency converge on a common ion channel as a potential therapeutic target for Pitt Hopkins syndrome.

Rannals MD, Page SC, Campbell MN, Gallo RA, Mayfield B, Maher BJ.

Rare Dis. 2016 Aug 5;4(1):e1220468. doi: 10.1080/21675511.2016.1220468. eCollection 2016.


Crucial roles of the Arp2/3 complex during mammalian corticogenesis.

Wang PS, Chou FS, Ramachandran S, Xia S, Chen HY, Guo F, Suraneni P, Maher BJ, Li R.

Development. 2016 Aug 1;143(15):2741-52. doi: 10.1242/dev.130542. Epub 2016 Jul 6.


A human-specific AS3MT isoform and BORCS7 are molecular risk factors in the 10q24.32 schizophrenia-associated locus.

Li M, Jaffe AE, Straub RE, Tao R, Shin JH, Wang Y, Chen Q, Li C, Jia Y, Ohi K, Maher BJ, Brandon NJ, Cross A, Chenoweth JG, Hoeppner DJ, Wei H, Hyde TM, McKay R, Kleinman JE, Weinberger DR.

Nat Med. 2016 Jun;22(6):649-56. doi: 10.1038/nm.4096. Epub 2016 May 9.


Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure.

Qian X, Nguyen HN, Song MM, Hadiono C, Ogden SC, Hammack C, Yao B, Hamersky GR, Jacob F, Zhong C, Yoon KJ, Jeang W, Lin L, Li Y, Thakor J, Berg DA, Zhang C, Kang E, Chickering M, Nauen D, Ho CY, Wen Z, Christian KM, Shi PY, Maher BJ, Wu H, Jin P, Tang H, Song H, Ming GL.

Cell. 2016 May 19;165(5):1238-1254. doi: 10.1016/j.cell.2016.04.032. Epub 2016 Apr 22.


Psychiatric Risk Gene Transcription Factor 4 Regulates Intrinsic Excitability of Prefrontal Neurons via Repression of SCN10a and KCNQ1.

Rannals MD, Hamersky GR, Page SC, Campbell MN, Briley A, Gallo RA, Phan BN, Hyde TM, Kleinman JE, Shin JH, Jaffe AE, Weinberger DR, Maher BJ.

Neuron. 2016 Apr 6;90(1):43-55. doi: 10.1016/j.neuron.2016.02.021. Epub 2016 Mar 10.


Schizophrenia-Associated hERG channel Kv11.1-3.1 Exhibits a Unique Trafficking Deficit that is Rescued Through Proteasome Inhibition for High Throughput Screening.

Calcaterra NE, Hoeppner DJ, Wei H, Jaffe AE, Maher BJ, Barrow JC.

Sci Rep. 2016 Feb 16;6:19976. doi: 10.1038/srep19976.


Early postnatal GABAA receptor modulation reverses deficits in neuronal maturation in a conditional neurodevelopmental mouse model of DISC1.

Saito A, Taniguchi Y, Rannals MD, Merfeld EB, Ballinger MD, Koga M, Ohtani Y, Gurley DA, Sedlak TW, Cross A, Moss SJ, Brandon NJ, Maher BJ, Kamiya A.

Mol Psychiatry. 2016 Oct;21(10):1449-59. doi: 10.1038/mp.2015.203. Epub 2016 Jan 5.


Developmental regulation of human cortex transcription and its clinical relevance at single base resolution.

Jaffe AE, Shin J, Collado-Torres L, Leek JT, Tao R, Li C, Gao Y, Jia Y, Maher BJ, Hyde TM, Kleinman JE, Weinberger DR.

Nat Neurosci. 2015 Jan;18(1):154-161. doi: 10.1038/nn.3898. Epub 2014 Dec 15.


Expression of ZNF804A in human brain and alterations in schizophrenia, bipolar disorder, and major depressive disorder: a novel transcript fetally regulated by the psychosis risk variant rs1344706.

Tao R, Cousijn H, Jaffe AE, Burnet PW, Edwards F, Eastwood SL, Shin JH, Lane TA, Walker MA, Maher BJ, Weinberger DR, Harrison PJ, Hyde TM, Kleinman JE.

JAMA Psychiatry. 2014 Oct;71(10):1112-20. doi: 10.1001/jamapsychiatry.2014.1079.


piggyBac transposon-mediated cellular transgenesis in mammalian forebrain by in utero electroporation.

Chen F, Maher BJ, LoTurco JJ.

Cold Spring Harb Protoc. 2014 Jul 1;2014(7):741-9. doi: 10.1101/pdb.prot073650.


Knockdown of the dyslexia-associated gene Kiaa0319 impairs temporal responses to speech stimuli in rat primary auditory cortex.

Centanni TM, Booker AB, Sloan AM, Chen F, Maher BJ, Carraway RS, Khodaparast N, Rennaker R, LoTurco JJ, Kilgard MP.

Cereb Cortex. 2014 Jul;24(7):1753-66. doi: 10.1093/cercor/bht028. Epub 2013 Feb 8.


Olig2-dependent developmental fate switch of NG2 cells.

Zhu X, Zuo H, Maher BJ, Serwanski DR, LoTurco JJ, Lu QR, Nishiyama A.

Development. 2012 Jul;139(13):2299-307. doi: 10.1242/dev.078873. Epub 2012 May 23.


Disrupted-in-schizophrenia (DISC1) functions presynaptically at glutamatergic synapses.

Maher BJ, LoTurco JJ.

PLoS One. 2012;7(3):e34053. doi: 10.1371/journal.pone.0034053. Epub 2012 Mar 30.


ZNF804a regulates expression of the schizophrenia-associated genes PRSS16, COMT, PDE4B, and DRD2.

Girgenti MJ, LoTurco JJ, Maher BJ.

PLoS One. 2012;7(2):e32404. doi: 10.1371/journal.pone.0032404. Epub 2012 Feb 27.


Experience-dependent maturation of the glomerular microcircuit.

Maher BJ, McGinley MJ, Westbrook GL.

Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16865-70. doi: 10.1073/pnas.0808946106. Epub 2009 Sep 11.


Stop and go GABA.

Maher BJ, LoTurco JJ.

Nat Neurosci. 2009 Jul;12(7):817-8. doi: 10.1038/nn0709-817. No abstract available.


Direct actions of carbenoxolone on synaptic transmission and neuronal membrane properties.

Tovar KR, Maher BJ, Westbrook GL.

J Neurophysiol. 2009 Aug;102(2):974-8. doi: 10.1152/jn.00060.2009. Epub 2009 Jun 17.


Larval survival of fuller's rose weevil, Naupactus cervinus, on common groundcover species in orchards of New Zealand kiwifruit.

Logan DP, Maher BJ, Dobson SS, Connolly PG.

J Insect Sci. 2008;8:1-10. doi: 10.1673/031.008.5101.


Co-transmission of dopamine and GABA in periglomerular cells.

Maher BJ, Westbrook GL.

J Neurophysiol. 2008 Mar;99(3):1559-64. doi: 10.1152/jn.00636.2007. Epub 2008 Jan 23.


SK channel regulation of dendritic excitability and dendrodendritic inhibition in the olfactory bulb.

Maher BJ, Westbrook GL.

J Neurophysiol. 2005 Dec;94(6):3743-50. Epub 2005 Aug 17.


Postsynaptic IP3 receptor-mediated Ca2+ release modulates synaptic transmission in hippocampal neurons.

Kelly PT, Mackinnon RL 2nd, Dietz RV, Maher BJ, Wang J.

Brain Res Mol Brain Res. 2005 Apr 27;135(1-2):232-48.


Activation of postsynaptic Ca(2+) stores modulates glutamate receptor cycling in hippocampal neurons.

Maher BJ, Mackinnon RL 2nd, Bai J, Chapman ER, Kelly PT.

J Neurophysiol. 2005 Jan;93(1):178-88.

Supplemental Content

Loading ...
Support Center