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Items: 1 to 50 of 67

1.

Plasma Proteome Signature of Sepsis: a Functionally Connected Protein Network.

Pimienta G, Heithoff DM, Rosa-Campos A, Tran M, Esko JD, Mahan MJ, Marth JD, Smith JW.

Proteomics. 2019 Mar;19(5):e1800389. doi: 10.1002/pmic.201800389. Epub 2019 Feb 20.

PMID:
30706660
2.

Accelerated Aging and Clearance of Host Anti-inflammatory Enzymes by Discrete Pathogens Fuels Sepsis.

Yang WH, Heithoff DM, Aziz PV, Haslund-Gourley B, Westman JS, Narisawa S, Pinkerton AB, Millán JL, Nizet V, Mahan MJ, Marth JD.

Cell Host Microbe. 2018 Oct 10;24(4):500-513.e5. doi: 10.1016/j.chom.2018.09.011.

PMID:
30308156
3.

Smartphone-based pathogen diagnosis in urinary sepsis patients.

Barnes L, Heithoff DM, Mahan SP, Fox GN, Zambrano A, Choe J, Fitzgibbons LN, Marth JD, Fried JC, Soh HT, Mahan MJ.

EBioMedicine. 2018 Oct;36:73-82. doi: 10.1016/j.ebiom.2018.09.001. Epub 2018 Sep 20.

4.

Recurrent infection progressively disables host protection against intestinal inflammation.

Yang WH, Heithoff DM, Aziz PV, Sperandio M, Nizet V, Mahan MJ, Marth JD.

Science. 2017 Dec 22;358(6370). pii: eaao5610. doi: 10.1126/science.aao5610.

5.

Correcting a Fundamental Flaw in the Paradigm for Antimicrobial Susceptibility Testing.

Ersoy SC, Heithoff DM, Barnes L 5th, Tripp GK, House JK, Marth JD, Smith JW, Mahan MJ.

EBioMedicine. 2017 Jun;20:173-181. doi: 10.1016/j.ebiom.2017.05.026. Epub 2017 May 29.

6.

Host-dependent Induction of Transient Antibiotic Resistance: A Prelude to Treatment Failure.

Kubicek-Sutherland JZ, Heithoff DM, Ersoy SC, Shimp WR, House JK, Marth JD, Smith JW, Mahan MJ.

EBioMedicine. 2015 Aug 11;2(9):1169-78. doi: 10.1016/j.ebiom.2015.08.012. eCollection 2015 Sep.

7.

An intrinsic mechanism of secreted protein aging and turnover.

Yang WH, Aziz PV, Heithoff DM, Mahan MJ, Smith JW, Marth JD.

Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):13657-62. doi: 10.1073/pnas.1515464112. Epub 2015 Oct 21.

8.

Pandemic influenza virus: tracking a three-headed monster.

Heithoff DM, Mahan MJ.

Virulence. 2015;6(5):405-6. doi: 10.1080/21505594.2015.1020275. Epub 2015 Mar 4. No abstract available.

9.

Development of a Salmonella cross-protective vaccine for food animal production systems.

Heithoff DM, House JK, Thomson PC, Mahan MJ.

Vaccine. 2015 Jan 1;33(1):100-7. doi: 10.1016/j.vaccine.2014.11.012. Epub 2014 Nov 20.

PMID:
25448106
10.

Immunization with a DNA adenine methylase over-producing Yersinia pseudotuberculosis vaccine confers robust cross-protection against heterologous pathogenic serotypes.

Kubicek-Sutherland JZ, Heithoff DM, Ersoy SC, Shimp WR, Mahan MJ.

Vaccine. 2014 Mar 14;32(13):1451-9. doi: 10.1016/j.vaccine.2014.01.036. Epub 2014 Feb 6.

PMID:
24508035
11.

Microfluidic chip-based detection and intraspecies strain discrimination of Salmonella serovars derived from whole blood of septic mice.

Patterson AS, Heithoff DM, Ferguson BS, Soh HT, Mahan MJ, Plaxco KW.

Appl Environ Microbiol. 2013 Apr;79(7):2302-11. doi: 10.1128/AEM.03882-12. Epub 2013 Jan 25.

12.

Rise of the microbes.

Mahan MJ, Kubicek-Sutherland JZ, Heithoff DM.

Virulence. 2013 Apr 1;4(3):213-22. doi: 10.4161/viru.23380. Epub 2013 Jan 18. Review.

13.

Salmonella cross-protective vaccines: fast-forward to the next generation of food safety.

Mahan MJ, Heithoff DM, House JK.

Future Microbiol. 2012 Jul;7(7):805-8. doi: 10.2217/fmb.12.60. No abstract available.

PMID:
22827301
14.

Intraspecies variation in the emergence of hyperinfectious bacterial strains in nature.

Heithoff DM, Shimp WR, House JK, Xie Y, Weimer BC, Sinsheimer RL, Mahan MJ.

PLoS Pathog. 2012;8(4):e1002647. doi: 10.1371/journal.ppat.1002647. Epub 2012 Apr 12.

15.

Development of a novel in-water vaccination protocol for DNA adenine methylase deficient Salmonella enterica serovar Typhimurium vaccine in adult sheep.

Mohler VL, Heithoff DM, Mahan MJ, Hornitzky MA, Thomson PC, House JK.

Vaccine. 2012 Feb 14;30(8):1481-91. doi: 10.1016/j.vaccine.2011.12.079. Epub 2011 Dec 31.

PMID:
22214887
16.

Protective immunity conferred by a DNA adenine methylase deficient Salmonella enterica serovar Typhimurium vaccine when delivered in-water to sheep challenged with Salmonella enterica serovar Typhimurium.

Mohler VL, Heithoff DM, Mahan MJ, Walker KH, Hornitzky MA, Gabor L, Thomson PC, Thompson A, House JK.

Vaccine. 2011 Apr 27;29(19):3571-82. doi: 10.1016/j.vaccine.2011.03.075. Epub 2011 Apr 5.

PMID:
21473951
17.

Conditions that diminish myeloid-derived suppressor cell activities stimulate cross-protective immunity.

Heithoff DM, Enioutina EY, Bareyan D, Daynes RA, Mahan MJ.

Infect Immun. 2008 Nov;76(11):5191-9. doi: 10.1128/IAI.00759-08. Epub 2008 Sep 2.

18.

Cross-protective immunity conferred by a DNA adenine methylase deficient Salmonella enterica serovar Typhimurium vaccine in calves challenged with Salmonella serovar Newport.

Mohler VL, Heithoff DM, Mahan MJ, Walker KH, Hornitzky MA, Shum LW, Makin KJ, House JK.

Vaccine. 2008 Mar 25;26(14):1751-8. doi: 10.1016/j.vaccine.2008.01.018. Epub 2008 Feb 4.

PMID:
18329764
19.

Human Salmonella clinical isolates distinct from those of animal origin.

Heithoff DM, Shimp WR, Lau PW, Badie G, Enioutina EY, Daynes RA, Byrne BA, House JK, Mahan MJ.

Appl Environ Microbiol. 2008 Mar;74(6):1757-66. doi: 10.1128/AEM.02740-07. Epub 2008 Feb 1.

20.
21.

In vivo-selected mutations in methyl-directed mismatch repair suppress the virulence attenuation of Salmonella dam mutant strains following intraperitoneal, but not oral, infection of naïve mice.

Heithoff DM, Badie G, Julio SM, Enioutina EY, Daynes RA, Sinsheimer RL, Mahan MJ.

J Bacteriol. 2007 Jul;189(13):4708-17. Epub 2007 Apr 27.

23.

Cross-protective immunity in calves conferred by a DNA adenine methylase deficient Salmonellaenterica serovar Typhimurium vaccine.

Mohler VL, Heithoff DM, Mahan MJ, Walker KH, Hornitzky MA, McConnell CS, Shum LW, House JK.

Vaccine. 2006 Feb 27;24(9):1339-45. Epub 2005 Oct 5.

PMID:
16300866
25.

Vibrio cholerae biofilms: stuck between a rock and a hard place.

Heithoff DM, Mahan MJ.

J Bacteriol. 2004 Aug;186(15):4835-7. No abstract available.

26.

Salmonella DNA adenine methylase mutants elicit early and late onset protective immune responses in calves.

Dueger EL, House JK, Heithoff DM, Mahan MJ.

Vaccine. 2003 Jul 4;21(23):3249-58.

PMID:
12804855
27.

Salmonella DNA adenine methylase mutants prevent colonization of newly hatched chickens by homologous and heterologous serovars.

Dueger EL, House JK, Heithoff DM, Mahan MJ.

Int J Food Microbiol. 2003 Jan 25;80(2):153-9.

PMID:
12381401
28.
29.
30.
31.

DNA adenine methylase is essential for viability and plays a role in the pathogenesis of Yersinia pseudotuberculosis and Vibrio cholerae.

Julio SM, Heithoff DM, Provenzano D, Klose KE, Sinsheimer RL, Low DA, Mahan MJ.

Infect Immun. 2001 Dec;69(12):7610-5.

32.

Roles of DNA adenine methylation in regulating bacterial gene expression and virulence.

Low DA, Weyand NJ, Mahan MJ.

Infect Immun. 2001 Dec;69(12):7197-204. Review. No abstract available.

33.

Salmonella DNA adenine methylase mutants confer cross-protective immunity.

Heithoff DM, Enioutina EY, Daynes RA, Sinsheimer RL, Low DA, Mahan MJ.

Infect Immun. 2001 Nov;69(11):6725-30.

34.

Assessment of bacterial pathogenesis by analysis of gene expression in the host.

Mahan MJ, Heithoff DM, Sinsheimer RL, Low DA.

Annu Rev Genet. 2000;34:139-164. Review.

PMID:
11092824
35.

In vivo gene expression and the adaptive response: from pathogenesis to vaccines and antimicrobials.

Heithoff DM, Sinsheimer RL, Low DA, Mahan MJ.

Philos Trans R Soc Lond B Biol Sci. 2000 May 29;355(1397):633-42. Review.

36.

In vivo-induced genes in Pseudomonas aeruginosa.

Handfield M, Lehoux DE, Sanschagrin F, Mahan MJ, Woods DE, Levesque RC.

Infect Immun. 2000 Apr;68(4):2359-62.

37.

ssrA (tmRNA) plays a role in Salmonella enterica serovar Typhimurium pathogenesis.

Julio SM, Heithoff DM, Mahan MJ.

J Bacteriol. 2000 Mar;182(6):1558-63.

38.

An essential role for DNA adenine methylation in bacterial virulence.

Heithoff DM, Sinsheimer RL, Low DA, Mahan MJ.

Science. 1999 May 7;284(5416):967-70.

39.

Coordinate intracellular expression of Salmonella genes induced during infection.

Heithoff DM, Conner CP, Hentschel U, Govantes F, Hanna PC, Mahan MJ.

J Bacteriol. 1999 Feb;181(3):799-807.

40.

Directed formation of chromosomal deletions in Salmonella typhimurium: targeting of specific genes induced during infection.

Julio SM, Conner CP, Heithoff DM, Mahan MJ.

Mol Gen Genet. 1998 Apr;258(1-2):178-81.

PMID:
9613587
41.

Differential patterns of acquired virulence genes distinguish Salmonella strains.

Conner CP, Heithoff DM, Julio SM, Sinsheimer RL, Mahan MJ.

Proc Natl Acad Sci U S A. 1998 Apr 14;95(8):4641-5.

42.

ASD-GFP vectors for in vivo expression technology in Pseudomonas aeruginosa and other gram-negative bacteria.

Handfield M, Schweizer HP, Mahan MJ, Sanschagrin F, Hoang T, Levesque RC.

Biotechniques. 1998 Feb;24(2):261-4.

43.

Dissecting the biology of a pathogen during infection.

Heithoff DM, Conner CP, Mahan MJ.

Trends Microbiol. 1997 Dec;5(12):509-13. Review.

PMID:
9447664
44.

In vivo gene expression: contributions to infection, virulence, and pathogenesis.

Conner CP, Heithoff DM, Mahan MJ.

Curr Top Microbiol Immunol. 1998;225:1-12. Review. No abstract available.

PMID:
9386325
45.

Single-step conjugative cloning of bacterial gene fusions involved in microbe-host interactions.

Rainey PB, Heithoff DM, Mahan MJ.

Mol Gen Genet. 1997 Sep;256(1):84-7.

PMID:
9341682
46.

Bacterial infection as assessed by in vivo gene expression.

Heithoff DM, Conner CP, Hanna PC, Julio SM, Hentschel U, Mahan MJ.

Proc Natl Acad Sci U S A. 1997 Feb 4;94(3):934-9.

48.

recB recJ mutants of Salmonella typhimurium are deficient in transductional recombination, DNA repair and plasmid maintenance.

Garzón A, Beuzón CR, Mahan MJ, Casadesús J.

Mol Gen Genet. 1996 Mar 20;250(5):570-80.

PMID:
8676860
49.
50.

Antibiotic-based selection for bacterial genes that are specifically induced during infection of a host.

Mahan MJ, Tobias JW, Slauch JM, Hanna PC, Collier RJ, Mekalanos JJ.

Proc Natl Acad Sci U S A. 1995 Jan 31;92(3):669-73.

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