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Items: 6

1.

GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126.

Mahamud MR, Geng X, Ho YC, Cha B, Kim Y, Ma J, Chen L, Myers G, Camper S, Mustacich D, Witte M, Choi D, Hong YK, Chen H, Varshney G, Engel JD, Wang S, Kim TH, Lim KC, Srinivasan RS.

Development. 2019 Nov 5;146(21). pii: dev184218. doi: 10.1242/dev.184218.

2.

Complementary Wnt Sources Regulate Lymphatic Vascular Development via PROX1-Dependent Wnt/β-Catenin Signaling.

Cha B, Geng X, Mahamud MR, Zhang JY, Chen L, Kim W, Jho EH, Kim Y, Choi D, Dixon JB, Chen H, Hong YK, Olson L, Kim TH, Merrill BJ, Davis MJ, Srinivasan RS.

Cell Rep. 2018 Oct 16;25(3):571-584.e5. doi: 10.1016/j.celrep.2018.09.049.

3.

Epsin deficiency promotes lymphangiogenesis through regulation of VEGFR3 degradation in diabetes.

Wu H, Rahman HNA, Dong Y, Liu X, Lee Y, Wen A, To KH, Xiao L, Birsner AE, Bazinet L, Wong S, Song K, Brophy ML, Mahamud MR, Chang B, Cai X, Pasula S, Kwak S, Yang W, Bischoff J, Xu J, Bielenberg DR, Dixon JB, D'Amato RJ, Srinivasan RS, Chen H.

J Clin Invest. 2018 Aug 31;128(9):4025-4043. doi: 10.1172/JCI96063. Epub 2018 Aug 13.

4.

Intraluminal valves: development, function and disease.

Geng X, Cha B, Mahamud MR, Srinivasan RS.

Dis Model Mech. 2017 Nov 1;10(11):1273-1287. doi: 10.1242/dmm.030825. Review.

5.

Mechanotransduction activates canonical Wnt/β-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valves.

Cha B, Geng X, Mahamud MR, Fu J, Mukherjee A, Kim Y, Jho EH, Kim TH, Kahn ML, Xia L, Dixon JB, Chen H, Srinivasan RS.

Genes Dev. 2016 Jun 15;30(12):1454-69. doi: 10.1101/gad.282400.116. Epub 2016 Jun 16.

6.

Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development.

Geng X, Cha B, Mahamud MR, Lim KC, Silasi-Mansat R, Uddin MKM, Miura N, Xia L, Simon AM, Engel JD, Chen H, Lupu F, Srinivasan RS.

Dev Biol. 2016 Jan 1;409(1):218-233. doi: 10.1016/j.ydbio.2015.10.022. Epub 2015 Nov 2.

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